JP2007512842A - シュードモナスにおける組換え二十面体ウイルス様粒子の生産 - Google Patents

シュードモナスにおける組換え二十面体ウイルス様粒子の生産 Download PDF

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JP2007512842A
JP2007512842A JP2006542692A JP2006542692A JP2007512842A JP 2007512842 A JP2007512842 A JP 2007512842A JP 2006542692 A JP2006542692 A JP 2006542692A JP 2006542692 A JP2006542692 A JP 2006542692A JP 2007512842 A JP2007512842 A JP 2007512842A
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peptide
virus
cell
capsid
recombinant
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ラソコバ，ラダ
ダオ，フィリップ，フック
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ダウ グローバル テクノロジーズ インコーポレイティド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
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    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/03—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14311—Parvovirus, e.g. minute virus of mice
    • C12N2750/14322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2770/00011—Details
    • C12N2770/14011—Bromoviridae
    • C12N2770/14023—Virus like particles [VLP]
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2006542692A 2003-12-01 2004-12-01 シュードモナスにおける組換え二十面体ウイルス様粒子の生産 Pending JP2007512842A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52598203P 2003-12-01 2003-12-01
PCT/US2004/040117 WO2005067478A2 (en) 2003-12-01 2004-12-01 Recombinant icosahedral virus like particle production in pseudomonads

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JP2007512842A true JP2007512842A (ja) 2007-05-24
JP2007512842A5 JP2007512842A5 (enExample) 2008-01-17

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JP2006542692A Pending JP2007512842A (ja) 2003-12-01 2004-12-01 シュードモナスにおける組換え二十面体ウイルス様粒子の生産

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US (1) US20050214321A1 (enExample)
EP (1) EP1758925A4 (enExample)
JP (1) JP2007512842A (enExample)
KR (1) KR20060114340A (enExample)
CN (1) CN101151272A (enExample)
AU (1) AU2004313458B2 (enExample)
BR (1) BRPI0417159A (enExample)
CA (1) CA2547511A1 (enExample)
MX (1) MXPA06006221A (enExample)
WO (1) WO2005067478A2 (enExample)

Cited By (11)

* Cited by examiner, † Cited by third party
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WO2010101237A1 (ja) * 2009-03-06 2010-09-10 アンジェスＭｇ株式会社 ポリペプチド及びその抗菌または消毒用途
WO2015005500A1 (en) * 2013-07-12 2015-01-15 Vlp Therapeutics, Llc Virus like particle comprising pd-1 antigen or pd-1 ligand antigen
US8969311B2 (en) 2009-05-25 2015-03-03 Anges Mg, Inc. Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide
US9376470B2 (en) 2008-11-28 2016-06-28 Funpep Inc. Polypeptide having angiogenesis-inducing activity and antibacterial activity, and use thereof for medical purposes
US9969986B2 (en) 2014-08-08 2018-05-15 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
US10098943B2 (en) 2014-09-11 2018-10-16 Vlp Therapeutics, Llc Flavivirus virus like particle
US10385101B2 (en) 2014-08-08 2019-08-20 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
US11345726B2 (en) 2012-02-16 2022-05-31 VLP Theranentics. Inc. Chikungunya virus (CHIKV) or Venezuelan equine encephalitis virus (VEEV) virus-like particles comprising heterologous antigens inserted into the envelope protein
US12134777B2 (en) 2020-04-30 2024-11-05 Vlp Therapeutics, Inc. Alphavirus replicon vector and immunotherapy by administering same
US12227770B2 (en) 2017-12-20 2025-02-18 Vlp Therapeutics, Inc. Alphavirus replicon particle
US12280102B2 (en) 2020-04-17 2025-04-22 Vlp Therapeutics, Inc. Alphavirus replicon encoding chimeric SARS-CoV-2 receptor binding domains

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US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
CA2547511A1 (en) * 2003-12-01 2005-07-28 Dow Global Technolgies Inc. Recombinant icosahedral virus like particle production in pseudomonads
US7928290B2 (en) * 2004-02-27 2011-04-19 Dow Agrosciences Llc Viral capsid fusion peptide expressing plant cells
BRPI0513826A2 (pt) 2004-07-26 2010-06-22 Dow Global Technologies Inc processo para expressão de proteìna melhorada através de engenharia de cepa
BRPI0611336A2 (pt) * 2005-06-01 2010-08-31 Dow Global Technologies Inc método para produzir uma partìcula multivalente semelhante a vìrus, partìcula multivalente semelhante a vìrus, método de aumentar a solubilidade de uma partìcula multivalente semelhante a vìrus e vacina
CA2615658A1 (en) * 2005-07-19 2007-01-25 Dow Global Technolgies Inc. Recombinant flu vaccines
WO2008027099A2 (en) * 2006-05-30 2008-03-06 Dow Global Technologies Inc. Rpa optimization
AT503690A1 (de) * 2006-06-09 2007-12-15 Biomay Ag Hypoallergene moleküle
US7998487B2 (en) * 2007-02-16 2011-08-16 The Salk Institute For Biological Studies Antitoxin and vaccine platform based on nodavirus VLPs
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
IN2012DN00324A (enExample) * 2009-06-15 2015-05-08 Plant Bioscience Ltd
RU2525136C1 (ru) * 2012-12-14 2014-08-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ получения препаративных количеств антигенов флоэмно-ограниченных вирусов
RU2555534C2 (ru) * 2013-05-23 2015-07-10 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ получения препаративных количеств вирусных частиц флоэмно-органиченных вирусов
CN103409377B (zh) * 2013-08-28 2015-12-23 中国农业科学院兰州兽医研究所 犬细小病毒病毒样颗粒的制备及用途
CN103882047B (zh) * 2014-03-18 2016-06-29 杨霞 重组人酸性成纤维细胞生长因子蛋白的制备方法
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN113278622B (zh) * 2021-06-09 2023-09-19 集美大学 一种变形假单胞菌适配体及其筛选方法
WO2024006433A1 (en) * 2022-06-30 2024-01-04 Carnegie Mellon University Method for production of virus-like particles for gene delivery

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Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9376470B2 (en) 2008-11-28 2016-06-28 Funpep Inc. Polypeptide having angiogenesis-inducing activity and antibacterial activity, and use thereof for medical purposes
JPWO2010101237A1 (ja) * 2009-03-06 2012-09-10 アンジェスＭｇ株式会社 ポリペプチド及びその抗菌または消毒用途
US8470765B2 (en) 2009-03-06 2013-06-25 Anges Mg, Inc. Polypeptides and antibacterial or antiseptic use of same
JP2015038108A (ja) * 2009-03-06 2015-02-26 アンジェスＭｇ株式会社 ポリペプチド及びその抗菌または消毒用途
JP2016104726A (ja) * 2009-03-06 2016-06-09 株式会社ファンペップ ポリペプチド及びその抗菌または消毒用途
WO2010101237A1 (ja) * 2009-03-06 2010-09-10 アンジェスＭｇ株式会社 ポリペプチド及びその抗菌または消毒用途
US9695219B2 (en) 2009-05-25 2017-07-04 Funpep Inc. Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide
US8969311B2 (en) 2009-05-25 2015-03-03 Anges Mg, Inc. Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide
US11345726B2 (en) 2012-02-16 2022-05-31 VLP Theranentics. Inc. Chikungunya virus (CHIKV) or Venezuelan equine encephalitis virus (VEEV) virus-like particles comprising heterologous antigens inserted into the envelope protein
JP2016526374A (ja) * 2013-07-12 2016-09-05 ブイエルピー・セラピューティクス・リミテッド・ライアビリティ・カンパニーＶＬＰ Ｔｈｅｒａｐｅｕｔｉｃｓ， ＬＬＣ Ｐｄ−１抗原またはｐｄ−１リガンド抗原を含むウイルス様粒子
US9637532B2 (en) 2013-07-12 2017-05-02 Vlp Therapeutics, Llc Virus like particle comprising PD-1 antigen or PD-1 ligand antigen
US10464986B2 (en) 2013-07-12 2019-11-05 Vlp Therapeutics, Llc Virus like particle comprising PD-1 antigen or PD-1 ligand antigen
WO2015005500A1 (en) * 2013-07-12 2015-01-15 Vlp Therapeutics, Llc Virus like particle comprising pd-1 antigen or pd-1 ligand antigen
US9969986B2 (en) 2014-08-08 2018-05-15 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
US10385101B2 (en) 2014-08-08 2019-08-20 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
US10098943B2 (en) 2014-09-11 2018-10-16 Vlp Therapeutics, Llc Flavivirus virus like particle
US12227770B2 (en) 2017-12-20 2025-02-18 Vlp Therapeutics, Inc. Alphavirus replicon particle
US12280102B2 (en) 2020-04-17 2025-04-22 Vlp Therapeutics, Inc. Alphavirus replicon encoding chimeric SARS-CoV-2 receptor binding domains
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CA2547511A1 (en) 2005-07-28
AU2004313458B2 (en) 2010-07-22
WO2005067478A2 (en) 2005-07-28
BRPI0417159A (pt) 2007-03-06
EP1758925A4 (en) 2009-04-08
EP1758925A2 (en) 2007-03-07
WO2005067478A3 (en) 2007-11-22
AU2004313458A1 (en) 2005-07-28
US20050214321A1 (en) 2005-09-29
CN101151272A (zh) 2008-03-26
KR20060114340A (ko) 2006-11-06

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