JP2007512285A5 - - Google Patents
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- Publication number
- JP2007512285A5 JP2007512285A5 JP2006540389A JP2006540389A JP2007512285A5 JP 2007512285 A5 JP2007512285 A5 JP 2007512285A5 JP 2006540389 A JP2006540389 A JP 2006540389A JP 2006540389 A JP2006540389 A JP 2006540389A JP 2007512285 A5 JP2007512285 A5 JP 2007512285A5
- Authority
- JP
- Japan
- Prior art keywords
- chemical substance
- chlorobenzyloxy
- benzenesulfonyl
- tetrahydro
- methoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000126 substance Substances 0.000 claims 7
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 claims 3
- HIBWHHQXUSKNOV-UHFFFAOYSA-N 7-[4-[(4-chlorophenyl)methoxy]phenyl]sulfonyl-8-methoxy-3-methyl-1,2,4,5-tetrahydro-3-benzazepine Chemical compound COC1=CC=2CCN(C)CCC=2C=C1S(=O)(=O)C(C=C1)=CC=C1OCC1=CC=C(Cl)C=C1 HIBWHHQXUSKNOV-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 claims 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 1
- 208000028017 Psychotic disease Diseases 0.000 claims 1
- 239000011976 maleic acid Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0327740.7A GB0327740D0 (en) | 2003-11-28 | 2003-11-28 | Novel compounds |
| PCT/EP2004/013416 WO2005051916A1 (en) | 2003-11-28 | 2004-11-25 | 7-[4-(4-chlorobenzyloxy) benzenesulfonyl]-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepinium maleate or tosylate as antipsychotics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007512285A JP2007512285A (ja) | 2007-05-17 |
| JP2007512285A5 true JP2007512285A5 (https=) | 2008-01-17 |
Family
ID=29798028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006540389A Pending JP2007512285A (ja) | 2003-11-28 | 2004-11-25 | 抗精神病薬としての７−［４−（４−クロロベンジルオキシ）ベンゼンスルホニル］−８−メトキシ−３−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンゾアゼピニウムマレエートもしくはトシレート |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20070275948A1 (https=) |
| EP (1) | EP1687279A1 (https=) |
| JP (1) | JP2007512285A (https=) |
| KR (1) | KR20060103322A (https=) |
| CN (1) | CN1906170A (https=) |
| AR (1) | AR046719A1 (https=) |
| AU (1) | AU2004293179A1 (https=) |
| BR (1) | BRPI0417029A (https=) |
| CA (1) | CA2547444A1 (https=) |
| GB (1) | GB0327740D0 (https=) |
| IL (1) | IL175663A0 (https=) |
| IS (1) | IS8500A (https=) |
| MA (1) | MA28177A1 (https=) |
| NO (1) | NO20062970L (https=) |
| RU (1) | RU2006122959A (https=) |
| TW (1) | TW200528433A (https=) |
| WO (1) | WO2005051916A1 (https=) |
| ZA (1) | ZA200603781B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0510599D0 (en) * | 2005-05-24 | 2005-06-29 | Glaxo Group Ltd | Novel compounds |
| GB0603087D0 (en) * | 2006-02-15 | 2006-03-29 | Glaxo Group Ltd | Novel use |
| KR101653548B1 (ko) * | 2008-01-08 | 2016-09-02 | 머크 샤프 앤드 돔 리미티드 | 2-｛4-［（3ｓ）-피페리딘-3-일］페닐｝-2ｈ-인다졸-7-카복스아미드의 약제학적으로 허용되는 염 |
| US20180228811A1 (en) * | 2014-12-12 | 2018-08-16 | The Schepens Eye Research Institute, Inc. | Gdnf induction for the treatment of retinal disorders |
| CN110446495B (zh) | 2017-02-17 | 2023-09-05 | 特维娜有限公司 | 含有7元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法 |
| JP2022504228A (ja) | 2018-10-03 | 2022-01-13 | テサロ， インコーポレイテッド | ニラパリブ遊離塩基の結晶形態 |
| WO2022093904A1 (en) * | 2020-10-27 | 2022-05-05 | Trevena, Inc. | Crystalline and amorphous forms of a delta-opioid modulator |
| CN115998724B (zh) * | 2023-03-28 | 2023-06-16 | 中国人民解放军军事科学院军事医学研究院 | 布洛芬在抗幻觉作用药物中的新用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005518414A (ja) * | 2001-12-21 | 2005-06-23 | スミスクライン ビーチャム パブリック リミテッド カンパニー | ドーパミン受容体のモジュレーターとしての７−スルホニル−３−ベンゾアゼピン誘導体およびｃｎｓ障害の治療のためのその使用 |
| MXPA04007920A (es) * | 2002-02-13 | 2004-11-26 | Glaxo Group Ltd | Derivados de bencensulfonamida como agentes antisicoticos. |
| AR040126A1 (es) * | 2002-05-29 | 2005-03-16 | Glaxo Group Ltd | Compuesto de fenilsulfonilo, composicion farmaceutica que lo comprende y su uso para la elaboracion de un medicamento |
-
2003
- 2003-11-28 GB GBGB0327740.7A patent/GB0327740D0/en not_active Ceased
-
2004
- 2004-11-25 BR BRPI0417029-6A patent/BRPI0417029A/pt not_active IP Right Cessation
- 2004-11-25 CN CNA2004800410778A patent/CN1906170A/zh active Pending
- 2004-11-25 CA CA002547444A patent/CA2547444A1/en not_active Abandoned
- 2004-11-25 WO PCT/EP2004/013416 patent/WO2005051916A1/en not_active Ceased
- 2004-11-25 JP JP2006540389A patent/JP2007512285A/ja active Pending
- 2004-11-25 US US10/580,640 patent/US20070275948A1/en not_active Abandoned
- 2004-11-25 RU RU2006122959/04A patent/RU2006122959A/ru not_active Application Discontinuation
- 2004-11-25 AU AU2004293179A patent/AU2004293179A1/en not_active Abandoned
- 2004-11-25 KR KR1020067010371A patent/KR20060103322A/ko not_active Withdrawn
- 2004-11-25 EP EP04819223A patent/EP1687279A1/en not_active Withdrawn
- 2004-11-26 AR ARP040104393A patent/AR046719A1/es not_active Application Discontinuation
- 2004-11-26 TW TW093136389A patent/TW200528433A/zh unknown
-
2006
- 2006-05-10 ZA ZA200600378A patent/ZA200603781B/xx unknown
- 2006-05-16 IL IL175663A patent/IL175663A0/en unknown
- 2006-05-24 MA MA29055A patent/MA28177A1/fr unknown
- 2006-06-08 IS IS8500A patent/IS8500A/xx unknown
- 2006-06-26 NO NO20062970A patent/NO20062970L/no not_active Application Discontinuation
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