ZA200603781B - 7-[4-(4-chlorobenzyloxy) benzenesulfonyl]-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepinium maleate or tosylate as antipsychotics - Google Patents
7-[4-(4-chlorobenzyloxy) benzenesulfonyl]-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepinium maleate or tosylate as antipsychoticsInfo
- Publication number
- ZA200603781B ZA200603781B ZA200600378A ZA200603781A ZA200603781B ZA 200603781 B ZA200603781 B ZA 200603781B ZA 200600378 A ZA200600378 A ZA 200600378A ZA 200603781 A ZA200603781 A ZA 200603781A ZA 200603781 B ZA200603781 B ZA 200603781B
- Authority
- ZA
- South Africa
- Prior art keywords
- chlorobenzyloxy
- antipsychotics
- benzenesulfonyl
- tosylate
- tetrahydro
- Prior art date
Links
- 239000000164 antipsychotic agent Substances 0.000 title 1
- 229940005529 antipsychotics Drugs 0.000 title 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 title 1
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 title 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 title 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0327740.7A GB0327740D0 (en) | 2003-11-28 | 2003-11-28 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200603781B true ZA200603781B (en) | 2007-09-26 |
Family
ID=29798028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200600378A ZA200603781B (en) | 2003-11-28 | 2006-05-10 | 7-[4-(4-chlorobenzyloxy) benzenesulfonyl]-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepinium maleate or tosylate as antipsychotics |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20070275948A1 (https=) |
| EP (1) | EP1687279A1 (https=) |
| JP (1) | JP2007512285A (https=) |
| KR (1) | KR20060103322A (https=) |
| CN (1) | CN1906170A (https=) |
| AR (1) | AR046719A1 (https=) |
| AU (1) | AU2004293179A1 (https=) |
| BR (1) | BRPI0417029A (https=) |
| CA (1) | CA2547444A1 (https=) |
| GB (1) | GB0327740D0 (https=) |
| IL (1) | IL175663A0 (https=) |
| IS (1) | IS8500A (https=) |
| MA (1) | MA28177A1 (https=) |
| NO (1) | NO20062970L (https=) |
| RU (1) | RU2006122959A (https=) |
| TW (1) | TW200528433A (https=) |
| WO (1) | WO2005051916A1 (https=) |
| ZA (1) | ZA200603781B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0510599D0 (en) * | 2005-05-24 | 2005-06-29 | Glaxo Group Ltd | Novel compounds |
| GB0603087D0 (en) * | 2006-02-15 | 2006-03-29 | Glaxo Group Ltd | Novel use |
| KR101653548B1 (ko) * | 2008-01-08 | 2016-09-02 | 머크 샤프 앤드 돔 리미티드 | 2-｛4-［（3ｓ）-피페리딘-3-일］페닐｝-2ｈ-인다졸-7-카복스아미드의 약제학적으로 허용되는 염 |
| US20180228811A1 (en) * | 2014-12-12 | 2018-08-16 | The Schepens Eye Research Institute, Inc. | Gdnf induction for the treatment of retinal disorders |
| CN110446495B (zh) | 2017-02-17 | 2023-09-05 | 特维娜有限公司 | 含有7元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法 |
| JP2022504228A (ja) | 2018-10-03 | 2022-01-13 | テサロ， インコーポレイテッド | ニラパリブ遊離塩基の結晶形態 |
| WO2022093904A1 (en) * | 2020-10-27 | 2022-05-05 | Trevena, Inc. | Crystalline and amorphous forms of a delta-opioid modulator |
| CN115998724B (zh) * | 2023-03-28 | 2023-06-16 | 中国人民解放军军事科学院军事医学研究院 | 布洛芬在抗幻觉作用药物中的新用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005518414A (ja) * | 2001-12-21 | 2005-06-23 | スミスクライン ビーチャム パブリック リミテッド カンパニー | ドーパミン受容体のモジュレーターとしての７−スルホニル−３−ベンゾアゼピン誘導体およびｃｎｓ障害の治療のためのその使用 |
| MXPA04007920A (es) * | 2002-02-13 | 2004-11-26 | Glaxo Group Ltd | Derivados de bencensulfonamida como agentes antisicoticos. |
| AR040126A1 (es) * | 2002-05-29 | 2005-03-16 | Glaxo Group Ltd | Compuesto de fenilsulfonilo, composicion farmaceutica que lo comprende y su uso para la elaboracion de un medicamento |
-
2003
- 2003-11-28 GB GBGB0327740.7A patent/GB0327740D0/en not_active Ceased
-
2004
- 2004-11-25 BR BRPI0417029-6A patent/BRPI0417029A/pt not_active IP Right Cessation
- 2004-11-25 CN CNA2004800410778A patent/CN1906170A/zh active Pending
- 2004-11-25 CA CA002547444A patent/CA2547444A1/en not_active Abandoned
- 2004-11-25 WO PCT/EP2004/013416 patent/WO2005051916A1/en not_active Ceased
- 2004-11-25 JP JP2006540389A patent/JP2007512285A/ja active Pending
- 2004-11-25 US US10/580,640 patent/US20070275948A1/en not_active Abandoned
- 2004-11-25 RU RU2006122959/04A patent/RU2006122959A/ru not_active Application Discontinuation
- 2004-11-25 AU AU2004293179A patent/AU2004293179A1/en not_active Abandoned
- 2004-11-25 KR KR1020067010371A patent/KR20060103322A/ko not_active Withdrawn
- 2004-11-25 EP EP04819223A patent/EP1687279A1/en not_active Withdrawn
- 2004-11-26 AR ARP040104393A patent/AR046719A1/es not_active Application Discontinuation
- 2004-11-26 TW TW093136389A patent/TW200528433A/zh unknown
-
2006
- 2006-05-10 ZA ZA200600378A patent/ZA200603781B/xx unknown
- 2006-05-16 IL IL175663A patent/IL175663A0/en unknown
- 2006-05-24 MA MA29055A patent/MA28177A1/fr unknown
- 2006-06-08 IS IS8500A patent/IS8500A/xx unknown
- 2006-06-26 NO NO20062970A patent/NO20062970L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TW200528433A (en) | 2005-09-01 |
| IL175663A0 (en) | 2006-09-05 |
| KR20060103322A (ko) | 2006-09-28 |
| EP1687279A1 (en) | 2006-08-09 |
| RU2006122959A (ru) | 2008-01-10 |
| WO2005051916A1 (en) | 2005-06-09 |
| US20070275948A1 (en) | 2007-11-29 |
| CA2547444A1 (en) | 2005-06-09 |
| AR046719A1 (es) | 2005-12-21 |
| AU2004293179A1 (en) | 2005-06-09 |
| MA28177A1 (fr) | 2006-09-01 |
| GB0327740D0 (en) | 2003-12-31 |
| BRPI0417029A (pt) | 2007-02-06 |
| JP2007512285A (ja) | 2007-05-17 |
| IS8500A (is) | 2006-06-08 |
| NO20062970L (no) | 2006-08-21 |
| CN1906170A (zh) | 2007-01-31 |
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