JP2007510757A5 - - Google Patents

Info

Publication number

JP2007510757A5

JP2007510757A5 JP2006539968A JP2006539968A JP2007510757A5 JP 2007510757 A5 JP2007510757 A5 JP 2007510757A5 JP 2006539968 A JP2006539968 A JP 2006539968A JP 2006539968 A JP2006539968 A JP 2006539968A JP 2007510757 A5 JP2007510757 A5 JP 2007510757A5

Authority

JP

Japan

Prior art keywords

cmt

eczema

pharmaceutical composition

composition according

antibacterial

Prior art date

2004-11-04

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 239000008194 pharmaceutical composition Substances 0.000 claims 14
• 230000000844 anti-bacterial effect Effects 0.000 claims 12
• 239000004098 Tetracycline Substances 0.000 claims 11
• 229960002180 tetracycline Drugs 0.000 claims 11
• 229930101283 tetracycline Natural products 0.000 claims 11
• 235000019364 tetracycline Nutrition 0.000 claims 11
• 150000003522 tetracyclines Chemical class 0.000 claims 11
• 208000010668 atopic eczema Diseases 0.000 claims 10
• 201000004624 Dermatitis Diseases 0.000 claims 8
• 239000000203 mixture Substances 0.000 claims 6
• 206010012442 Dermatitis contact Diseases 0.000 claims 4
• 241000124008 Mammalia Species 0.000 claims 4
• 208000010247 contact dermatitis Diseases 0.000 claims 4
• 238000009472 formulation Methods 0.000 claims 3
• NBRQRXRBIHVLGI-OWXODZSWSA-N (4as,5ar,12ar)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1C2=CC=CC(O)=C2C(O)=C(C2=O)[C@@H]1C[C@@H]1[C@@]2(O)C(O)=C(C(=O)N)C(=O)C1 NBRQRXRBIHVLGI-OWXODZSWSA-N 0.000 claims 2
• SGKRLCUYIXIAHR-AKNGSSGZSA-N (4s,4ar,5s,5ar,6r,12ar)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1=CC=C2[C@H](C)[C@@H]([C@H](O)[C@@H]3[C@](C(O)=C(C(N)=O)C(=O)[C@H]3N(C)C)(O)C3=O)C3=C(O)C2=C1O SGKRLCUYIXIAHR-AKNGSSGZSA-N 0.000 claims 2
• FFTVPQUHLQBXQZ-KVUCHLLUSA-N (4s,4as,5ar,12ar)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1C2=C(N(C)C)C=CC(O)=C2C(O)=C2[C@@H]1C[C@H]1[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]1(O)C2=O FFTVPQUHLQBXQZ-KVUCHLLUSA-N 0.000 claims 2
• 208000002874 Acne Vulgaris Diseases 0.000 claims 2
• 206010012434 Dermatitis allergic Diseases 0.000 claims 2
• 206010012438 Dermatitis atopic Diseases 0.000 claims 2
• 201000009053 Neurodermatitis Diseases 0.000 claims 2
• 206010039793 Seborrhoeic dermatitis Diseases 0.000 claims 2
• 206010000496 acne Diseases 0.000 claims 2
• 230000000172 allergic effect Effects 0.000 claims 2
• 201000008937 atopic dermatitis Diseases 0.000 claims 2
• BVFDLIAWTKFZQD-JXVDNWKRSA-N cmt-8 Chemical compound O=C1C2=C(O)C=CC=C2C(C)[C@@H]2C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)C[C@@H]1C2O BVFDLIAWTKFZQD-JXVDNWKRSA-N 0.000 claims 2
• 229960003722 doxycycline Drugs 0.000 claims 2
• 229960004023 minocycline Drugs 0.000 claims 2
• 208000008742 seborrheic dermatitis Diseases 0.000 claims 2
• 230000000845 anti-microbial effect Effects 0.000 claims 1