JP2007509946A5 - - Google Patents
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- Publication number
- JP2007509946A5 JP2007509946A5 JP2006538169A JP2006538169A JP2007509946A5 JP 2007509946 A5 JP2007509946 A5 JP 2007509946A5 JP 2006538169 A JP2006538169 A JP 2006538169A JP 2006538169 A JP2006538169 A JP 2006538169A JP 2007509946 A5 JP2007509946 A5 JP 2007509946A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutical composition
- acid
- methylenebis
- phenoxyisobutyric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51447603P | 2003-10-27 | 2003-10-27 | |
| US60/514,476 | 2003-10-27 | ||
| PCT/US2004/035440 WO2005044251A2 (en) | 2003-10-27 | 2004-10-27 | Methods of lowering lipid levels in a mammal |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007509946A JP2007509946A (ja) | 2007-04-19 |
| JP2007509946A5 true JP2007509946A5 (https=) | 2007-11-22 |
| JP4976851B2 JP4976851B2 (ja) | 2012-07-18 |
Family
ID=34572758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006538169A Expired - Fee Related JP4976851B2 (ja) | 2003-10-27 | 2004-10-27 | 脂質レベルを哺乳動物において低下させる方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7320988B2 (https=) |
| EP (2) | EP2269601A1 (https=) |
| JP (1) | JP4976851B2 (https=) |
| AU (1) | AU2004287434B2 (https=) |
| CA (1) | CA2543611A1 (https=) |
| WO (1) | WO2005044251A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4976851B2 (ja) * | 2003-10-27 | 2012-07-18 | シティ・オブ・ホープ | 脂質レベルを哺乳動物において低下させる方法 |
| WO2007044309A2 (en) * | 2005-10-05 | 2007-04-19 | Vasix Corporation | Device and method for inhibiting age complex formation |
| US8580854B2 (en) * | 2005-11-09 | 2013-11-12 | City Of Hope | Methods of suppression of rage gene expression and rage triggered inflammatory genes by selected age-inhibitors |
| US8124655B2 (en) * | 2007-06-15 | 2012-02-28 | City Of Hope | Use of LR-90 and LR-102 to overcome insulin resistance |
| US9808434B2 (en) | 2011-01-27 | 2017-11-07 | City Of Hope | Compound for treating cancer and diabetes |
| WO2012103523A2 (en) | 2011-01-27 | 2012-08-02 | Samuel Rahbar | Novel modulators of development of adipocyte and cancer cells |
| US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
| WO2020190984A1 (en) * | 2019-03-19 | 2020-09-24 | City Of Hope | Compounds for the treatment of neuropathic pain |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US514476A (en) | 1894-02-13 | Minnow-bucket | ||
| JPS57500432A (https=) | 1980-03-20 | 1982-03-11 | ||
| US5700447A (en) * | 1992-05-21 | 1997-12-23 | The Picowder Institute For Medical Research | Methods and materials for the diagnosis and treatment of conditions such as stroke |
| US5100919A (en) | 1984-03-19 | 1992-03-31 | The Rockefeller University | Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein |
| US5272176A (en) | 1984-03-19 | 1993-12-21 | The Rockefeller University | Advanced glycation inhibitors containing amino-benzoic acids and derivatives, and methods of use |
| DE3410927A1 (de) | 1984-03-24 | 1985-10-03 | Hoechst Ag, 6230 Frankfurt | Vollaromatische polyester, verfahren zu ihrer herstellung und entsprechende formkoerper |
| US4801610A (en) | 1984-05-21 | 1989-01-31 | G. D. Searle & Co. | Phenolic ester derivatives as elastase inhibitors |
| US4603144A (en) | 1984-08-16 | 1986-07-29 | G. D. Searle & Co. | Kojic acid ether-ester derivatives |
| US5268500A (en) | 1987-06-15 | 1993-12-07 | Montefiore Medical Center | Compound, composition and method for the reduction of lipids the modification of the affinity of hemoblogin for oxygen and the prevention of platelet aggregation |
| US4921997A (en) | 1988-06-15 | 1990-05-01 | Montefiore Medical Center | Method of synthesis and novel compounds for pharmaceutical uses |
| US5093367A (en) | 1988-06-15 | 1992-03-03 | Montefiore Medical Center | Method of synthesis and novel compounds for pharmaceutical uses |
| US5677330A (en) * | 1990-02-12 | 1997-10-14 | The Center For Innovative Technology | Medical uses of allosteric hemoglobin modifier compounds in patient care |
| US6046222A (en) | 1993-09-15 | 2000-04-04 | Warner-Lambert Company | Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
| US5833700A (en) | 1995-03-15 | 1998-11-10 | Ethicon Endo-Surgery, Inc. | Sterile occlusion fasteners and instrument and method for their placement |
| WO1995031192A1 (en) | 1994-05-16 | 1995-11-23 | Thomas Jefferson University | Method and use of agents to inhibit protein polymerization and methods of identifying these agents |
| US5661139A (en) | 1995-01-13 | 1997-08-26 | Alteon Inc. | Bis-(2-aryl) hydrazones |
| US5962651A (en) | 1995-01-27 | 1999-10-05 | Montefiore Medical Center | Modified hemoglobin and its use as a component of an artificial blood substitute |
| US5602277A (en) | 1995-03-30 | 1997-02-11 | Biocryst Pharmaceuticals, Inc. | Substituted benzene derivatives useful as neuraminidase inhibitors |
| US5667330A (en) | 1995-11-28 | 1997-09-16 | Case Corporation | Quick-connect mechanism for releasably retaining a power take-off shaft within an output shaft hub |
| US5716987A (en) | 1996-06-21 | 1998-02-10 | Bristol-Myers Squibb Company | Prophylactic and therapeutic treatment of skin sensitization and irritation |
| ES2197689T3 (es) * | 1998-10-22 | 2004-01-01 | University Of South Carolina | Procedimientos para inhibir complicaciones diabeticas. |
| US6605642B2 (en) | 1999-04-05 | 2003-08-12 | City Of Hope | Inhibitors of formation of advanced glycation endproducts (AGES) |
| US6787566B2 (en) | 1999-04-05 | 2004-09-07 | City Of Hope | Breakers of advanced glycation endproducts |
| WO2000059875A2 (en) | 1999-04-05 | 2000-10-12 | City Of Hope | Novel inhibitors of formation of advanced glycation endproducts (age's) |
| US6589944B1 (en) * | 1999-04-05 | 2003-07-08 | City Of Hope | Breakers of advanced glycation endproducts |
| US7030133B2 (en) | 1999-04-05 | 2006-04-18 | City Of Hope | Inhibitors of formation of advanced glycation endproducts (AGEs) |
| WO2000066102A2 (en) | 1999-04-29 | 2000-11-09 | City Of Hope | Pentoxifylline, pioglitazone and metformin are inhibitors of formation of advanced glycation endproducts (age's) |
| CA2393722A1 (en) | 1999-12-13 | 2002-06-14 | President And Fellows Of Harvard College | Methods for treating cell death diseases and inflammation |
| FR2836474B1 (fr) | 2002-02-22 | 2004-12-24 | Synt Em | Composes, compositions et methode pour le transport des molecules de cyclosporine a travers la barriere hemato-encephalique |
| JP4976851B2 (ja) * | 2003-10-27 | 2012-07-18 | シティ・オブ・ホープ | 脂質レベルを哺乳動物において低下させる方法 |
-
2004
- 2004-10-27 JP JP2006538169A patent/JP4976851B2/ja not_active Expired - Fee Related
- 2004-10-27 US US10/974,028 patent/US7320988B2/en not_active Expired - Lifetime
- 2004-10-27 CA CA002543611A patent/CA2543611A1/en not_active Abandoned
- 2004-10-27 EP EP20100183235 patent/EP2269601A1/en not_active Withdrawn
- 2004-10-27 EP EP04796420A patent/EP1682114A2/en not_active Ceased
- 2004-10-27 AU AU2004287434A patent/AU2004287434B2/en not_active Ceased
- 2004-10-27 WO PCT/US2004/035440 patent/WO2005044251A2/en not_active Ceased
-
2007
- 2007-11-30 US US11/948,574 patent/US7652037B2/en not_active Expired - Lifetime
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