JP2007508527A5 - - Google Patents
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- JP2007508527A5 JP2007508527A5 JP2006530040A JP2006530040A JP2007508527A5 JP 2007508527 A5 JP2007508527 A5 JP 2007508527A5 JP 2006530040 A JP2006530040 A JP 2006530040A JP 2006530040 A JP2006530040 A JP 2006530040A JP 2007508527 A5 JP2007508527 A5 JP 2007508527A5
- Authority
- JP
- Japan
- Prior art keywords
- organ damage
- end organ
- marker
- level
- risk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03078161A EP1522857A1 (en) | 2003-10-09 | 2003-10-09 | Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2 |
| EP03078161.1 | 2003-10-09 | ||
| PCT/EP2004/010879 WO2005040817A1 (en) | 2003-10-09 | 2004-09-27 | Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010167334A Division JP2010279378A (ja) | 2003-10-09 | 2010-07-26 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
| JP2011088342A Division JP5580774B2 (ja) | 2003-10-09 | 2011-04-12 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007508527A JP2007508527A (ja) | 2007-04-05 |
| JP2007508527A5 true JP2007508527A5 (enExample) | 2007-08-02 |
| JP4840744B2 JP4840744B2 (ja) | 2011-12-21 |
Family
ID=34306912
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006530040A Expired - Fee Related JP4840744B2 (ja) | 2003-10-09 | 2004-09-27 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
| JP2010167334A Withdrawn JP2010279378A (ja) | 2003-10-09 | 2010-07-26 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
| JP2011088342A Expired - Lifetime JP5580774B2 (ja) | 2003-10-09 | 2011-04-12 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
| JP2014021394A Expired - Lifetime JP5789009B2 (ja) | 2003-10-09 | 2014-02-06 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
| JP2015081540A Pending JP2015171365A (ja) | 2003-10-09 | 2015-04-13 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010167334A Withdrawn JP2010279378A (ja) | 2003-10-09 | 2010-07-26 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
| JP2011088342A Expired - Lifetime JP5580774B2 (ja) | 2003-10-09 | 2011-04-12 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
| JP2014021394A Expired - Lifetime JP5789009B2 (ja) | 2003-10-09 | 2014-02-06 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
| JP2015081540A Pending JP2015171365A (ja) | 2003-10-09 | 2015-04-13 | ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US7888137B2 (enExample) |
| EP (4) | EP1522857A1 (enExample) |
| JP (5) | JP4840744B2 (enExample) |
| CN (2) | CN1879022B (enExample) |
| AT (1) | ATE532073T1 (enExample) |
| AU (2) | AU2004284496C1 (enExample) |
| CA (2) | CA2542033C (enExample) |
| CY (2) | CY1112359T1 (enExample) |
| DK (2) | DK2317324T3 (enExample) |
| ES (2) | ES2530567T3 (enExample) |
| PL (2) | PL1682907T3 (enExample) |
| PT (2) | PT2317324E (enExample) |
| SI (2) | SI1682907T1 (enExample) |
| WO (1) | WO2005040817A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1522857A1 (en) * | 2003-10-09 | 2005-04-13 | Universiteit Maastricht | Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2 |
| AU2007301981A1 (en) * | 2006-09-25 | 2008-04-03 | Universiteit Maastricht | Means and methods for diagnosing and/or treating a subject at risk of developing heart failure |
| US20100055723A1 (en) * | 2007-01-23 | 2010-03-04 | University Of Virginia Patent Foundation | Galectin-3-Binding Protein as a Biomarker of Cardiovascular Disease |
| AU2008302489A1 (en) * | 2007-09-17 | 2009-03-26 | Bg Medicine, Inc. | Assessing congestive heart risk in patients treated or potentially to be treated with a peroxisome-proliferator-activator-receptor-gamma agonist or a thiazolidinedione |
| AU2009340423B2 (en) * | 2008-10-29 | 2014-07-24 | Bg Medicine, Inc. | Galectin-3 immunoassay |
| CN102576028A (zh) * | 2009-08-25 | 2012-07-11 | 保函医药公司 | 半乳凝集素-3和心脏再同步疗法 |
| JP2013536408A (ja) * | 2010-07-02 | 2013-09-19 | ビージー メディシン, インコーポレイテッド | ガレクチン−3測定によりモニタリングされるスタチン療法 |
| EP2631656B1 (en) * | 2010-10-18 | 2016-07-27 | Hideaki Hara | Marker for amyotrophic lateral sclerosis, and use thereof |
| EP2460890A1 (en) | 2010-12-01 | 2012-06-06 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | Gpnmb/Osteoactivin as a drug target and biomarker in cardiac diseases |
| CA2825954A1 (en) * | 2011-01-31 | 2012-08-09 | Bg Medicine, Inc. | Use of galectin-3 for detecting and prognosing heart failure after acute coronary syndrome |
| US8728742B2 (en) | 2011-03-17 | 2014-05-20 | Critical Care Diagnostics, Inc. | Methods predicting risk of an adverse clinical outcome |
| AR086543A1 (es) | 2011-05-25 | 2014-01-08 | Bg Medicine Inc | Inhibidores de galectina-3 y metodos de uso de los mismos, composicion farmaceutica |
| ES2669068T3 (es) * | 2011-12-08 | 2018-05-23 | Eliaz Therapeutics, Inc | Reducción de niveles de galectina-3 mediante plasmaféresis |
| ES2742291T3 (es) * | 2012-09-27 | 2020-02-13 | Siemens Healthcare Diagnostics Inc | Cistatina C y Galectina-3 como biomarcadores para la hipertensión arterial pulmonar |
| EP2919802A4 (en) * | 2012-11-15 | 2016-09-14 | Univ Tufts | METHOD, COMPOSITIONS AND KITS FOR TREATING, MODULATING OR PREVENTING ANGIOGENESIS OR FIBROSIS IN A PATIENT USING A GALECTINE PROTEIN HEMMER |
| WO2016113720A1 (en) | 2015-01-18 | 2016-07-21 | Diasorin S.P.A. | Use of 1,25-dihydroxyvitamin d values in ratio with pth as a prognostic biomarker |
| JP6612864B2 (ja) * | 2015-05-28 | 2019-11-27 | 京セラ株式会社 | 切削工具 |
| CN112553335A (zh) * | 2020-12-17 | 2021-03-26 | 核工业总医院 | 肾细胞癌生物标志物及其应用 |
| CN118524852A (zh) * | 2021-11-09 | 2024-08-20 | 真和制药有限公司 | 治疗或抑制心血管疾病的方法 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4632901A (en) | 1984-05-11 | 1986-12-30 | Hybritech Incorporated | Method and apparatus for immunoassays |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4704692A (en) | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| AU2684488A (en) | 1988-06-27 | 1990-01-04 | Carter-Wallace, Inc. | Test device and method for colored particle immunoassay |
| US6319676B1 (en) | 1995-05-02 | 2001-11-20 | Carter Wallace, Inc. | Diagnostic detection device and method |
| BE1010935A7 (nl) * | 1997-02-19 | 1999-03-02 | Delanghe Joris Richard Siegfri | Fenotypering van humaan haptoglobine in serum of plasma door middel van quantitatieve agglutinatie met streptococcus antigenen. |
| JP5264026B2 (ja) | 1997-06-10 | 2013-08-14 | エルパス・インコーポレイテッド | 心疾患の早期発見のための方法 |
| DK1018018T3 (da) * | 1997-09-05 | 2010-11-15 | Southern Medical Diagnostics Pty | Fremgangsmåde til diagnosticering |
| US20060166276A1 (en) * | 1997-09-05 | 2006-07-27 | Lung Health Diagnostics Pty Ltd | Method of diagnosis and agents useful for same |
| ES2244052T5 (es) * | 1997-10-24 | 2011-03-28 | SHIONOGI & CO., LTD. | Procedimiento de inhibición de la descomposición de péptidos natriuréticos y procedimento mejorado de dosificado de péptidos natriuréticos con la ayuda de los indicados péptidos. |
| JP5030329B2 (ja) * | 1998-04-02 | 2012-09-19 | ジェネンテック, インコーポレイテッド | 心臓肥大の処置 |
| PL204235B1 (pl) * | 1999-01-29 | 2009-12-31 | Roche Diagnostics Gmbh | Sposób wykrywania natywnego N-końcowego proBNP, zastosowanie tego sposobu, zastosowanie zrekombinowanego N-końcowego proBNP, przeciwciała przeciw zrekombinowanemu N-końcowemu proBNP, linie komórkowe i sposoby wytwarzania przeciwciał poliklonalnych i monoklonalnych |
| DE60031512T2 (de) * | 1999-02-19 | 2007-08-23 | University Of Iowa Research Foundation | Diagnostika und therapeutika für maculare degeneration |
| WO2001014581A2 (en) * | 1999-08-20 | 2001-03-01 | Board Of Regents, The University Of Texas System | Hdac4 and hdac5 in the regulation of cardiac gene expression |
| AU3087801A (en) | 2000-02-04 | 2001-08-14 | Molecular Dynamics Inc | Human genome-derived single exon nucleic acid probes useful for analysis of geneexpression in human breast and hbl 100 cells |
| AU2001251351A1 (en) | 2000-04-05 | 2001-10-23 | Incyte Genomics, Inc. | Genes expressed in foam cell differentiation |
| KR100395254B1 (ko) | 2000-10-30 | 2003-08-21 | (주)자리타 바이오텍 | 종양 발생 예측 키트 |
| AU2002218026A1 (en) * | 2000-11-09 | 2002-05-21 | The Brigham And Women's Hospital, Inc. | Cardiovascular disease diagnostic and therapeutic targets |
| US20030166017A1 (en) * | 2000-11-09 | 2003-09-04 | Millennium Pharmaceuticals, Inc. | Compositions and methods for the identification, assessment, prevention and therapy of cardiovascular disease |
| EP1385993B8 (en) * | 2000-12-08 | 2011-09-21 | Celldex Therapeutics, Inc. | Method of detecting and treating tuberous sclerosis complex associated disorders |
| JP4035562B2 (ja) * | 2001-01-31 | 2008-01-23 | 国立大学法人富山大学 | ガレクチン−3誘導能を利用した物質のスクリーニング方法、肝の状態の診断方法およびこれらの方法を利用したキット |
| US7041449B2 (en) | 2001-03-19 | 2006-05-09 | Wisconsin Alumni Research Foundation | Methods of screening for compounds that inhibit expression of biomarker sequences differentially expressed with age in mice |
| US20060019235A1 (en) | 2001-07-02 | 2006-01-26 | The Board Of Trustees Of The Leland Stanford Junior University | Molecular and functional profiling using a cellular microarray |
| US7447594B2 (en) | 2001-07-10 | 2008-11-04 | Ocimum Biosolutions, Inc. | Molecular cardiotoxicology modeling |
| US20030099958A1 (en) * | 2001-09-05 | 2003-05-29 | Vitivity, Inc. | Diagnosis and treatment of vascular disease |
| GB0124145D0 (en) | 2001-10-08 | 2001-11-28 | Bayer Ag | Genes and proteins for prevention,prediction,prognosis and therapy of cardiovascular disease |
| US20060141493A1 (en) | 2001-11-09 | 2006-06-29 | Duke University Office Of Science And Technology | Atherosclerotic phenotype determinative genes and methods for using the same |
| ATE405670T1 (de) * | 2002-05-13 | 2008-09-15 | Arexis Ab | Autoimmunerkrankungen und nadph-oxidase-defekte |
| AU2003290537A1 (en) | 2002-10-24 | 2004-05-13 | Duke University | Binary prediction tree modeling with many predictors and its uses in clinical and genomic applications |
| CA2505416A1 (en) | 2002-11-21 | 2004-06-10 | Wyeth | Methods for diagnosing rcc and other solid tumors |
| EP1431399A1 (en) * | 2002-12-20 | 2004-06-23 | Clinigenetics | Methods and composition for identifying therapeutic agents of atherosclerotic plaque lesions |
| US6889083B2 (en) | 2003-04-21 | 2005-05-03 | Medtronic, Inc. | Atrial tracking recovery to restore cardiac resynchronization therapy in dual chamber tracking modes |
| WO2005020784A2 (en) | 2003-05-23 | 2005-03-10 | Mount Sinai School Of Medicine Of New York University | Surrogate cell gene expression signatures for evaluating the physical state of a subject |
| WO2004111654A2 (en) | 2003-06-06 | 2004-12-23 | Ciphergen Biosystems, Inc. | Serum biomarkers in ischaemic heart disease |
| US20050106100A1 (en) | 2003-09-03 | 2005-05-19 | Harris Thomas D. | Compounds containing matrix metalloproteinase substrates and methods of their use |
| EP1560025A3 (en) * | 2003-10-03 | 2011-09-07 | F. Hoffmann-La Roche AG | Specific markers for diabetes |
| EP1522857A1 (en) * | 2003-10-09 | 2005-04-13 | Universiteit Maastricht | Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2 |
| DE10347436B4 (de) | 2003-10-13 | 2007-08-02 | Johann Wolfgang Goethe-Universität Frankfurt am Main | In vitro Verfahren zur Diagnose der kardiovaskulären Funktionalität von Blut-abgeleiteter zirkulierender Vorläuferzellen (BDP) |
| EP1720562A4 (en) | 2004-01-15 | 2009-10-28 | Scios Inc | METHOD FOR TREATING CARDIAL REMODELING AFTER MYOCARDIAL DAMAGE |
| WO2006026074A2 (en) | 2004-08-04 | 2006-03-09 | Duke University | Atherosclerotic phenotype determinative genes and methods for using the same |
| EP1846576A4 (en) | 2005-02-01 | 2009-01-07 | Us Gov Health & Human Serv | BIOMARKERS OF TISSUE STATUS |
| WO2006102497A2 (en) | 2005-03-22 | 2006-09-28 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for diagnosis, monitoring and development of therapeutics for treatment of atherosclerotic disease |
| US7632634B2 (en) | 2005-04-15 | 2009-12-15 | University Of Maryland Biotechnology Institute | Method and assay for early diagnosis of prostate cancer |
| US9592970B2 (en) | 2008-07-17 | 2017-03-14 | Toby D. Henderson | Robotic gantry with end effector for product lifting |
| AU2009340423B2 (en) | 2008-10-29 | 2014-07-24 | Bg Medicine, Inc. | Galectin-3 immunoassay |
| CN102576028A (zh) | 2009-08-25 | 2012-07-11 | 保函医药公司 | 半乳凝集素-3和心脏再同步疗法 |
-
2003
- 2003-10-09 EP EP03078161A patent/EP1522857A1/en not_active Withdrawn
-
2004
- 2004-09-27 DK DK10186331.4T patent/DK2317324T3/en active
- 2004-09-27 ES ES10186331T patent/ES2530567T3/es not_active Expired - Lifetime
- 2004-09-27 PL PL04765681T patent/PL1682907T3/pl unknown
- 2004-09-27 EP EP04765681A patent/EP1682907B1/en not_active Expired - Lifetime
- 2004-09-27 PT PT101863314T patent/PT2317324E/pt unknown
- 2004-09-27 DK DK04765681.4T patent/DK1682907T3/da active
- 2004-09-27 CN CN2004800332637A patent/CN1879022B/zh not_active Expired - Fee Related
- 2004-09-27 EP EP10186331.4A patent/EP2317324B1/en not_active Expired - Lifetime
- 2004-09-27 EP EP14192739.2A patent/EP2919012A1/en not_active Withdrawn
- 2004-09-27 SI SI200431813T patent/SI1682907T1/sl unknown
- 2004-09-27 ES ES04765681T patent/ES2377012T3/es not_active Expired - Lifetime
- 2004-09-27 CN CN201210321227.7A patent/CN102998458B/zh not_active Expired - Fee Related
- 2004-09-27 AT AT04765681T patent/ATE532073T1/de active
- 2004-09-27 JP JP2006530040A patent/JP4840744B2/ja not_active Expired - Fee Related
- 2004-09-27 US US10/575,745 patent/US7888137B2/en active Active
- 2004-09-27 PT PT04765681T patent/PT1682907E/pt unknown
- 2004-09-27 WO PCT/EP2004/010879 patent/WO2005040817A1/en not_active Ceased
- 2004-09-27 AU AU2004284496A patent/AU2004284496C1/en not_active Ceased
- 2004-09-27 PL PL10186331T patent/PL2317324T3/pl unknown
- 2004-09-27 SI SI200432221T patent/SI2317324T1/sl unknown
- 2004-09-27 CA CA2542033A patent/CA2542033C/en not_active Expired - Lifetime
- 2004-09-27 CA CA2842308A patent/CA2842308A1/en not_active Abandoned
-
2009
- 2009-10-19 AU AU2009227844A patent/AU2009227844B2/en not_active Ceased
-
2010
- 2010-07-26 JP JP2010167334A patent/JP2010279378A/ja not_active Withdrawn
- 2010-10-28 US US12/914,329 patent/US8084276B2/en not_active Expired - Fee Related
-
2011
- 2011-04-12 JP JP2011088342A patent/JP5580774B2/ja not_active Expired - Lifetime
- 2011-11-23 US US13/304,145 patent/US20120220532A1/en not_active Abandoned
-
2012
- 2012-02-01 CY CY20121100108T patent/CY1112359T1/el unknown
-
2013
- 2013-03-08 US US13/791,350 patent/US20130189716A1/en not_active Abandoned
-
2014
- 2014-02-06 JP JP2014021394A patent/JP5789009B2/ja not_active Expired - Lifetime
- 2014-05-05 US US14/269,707 patent/US20150037353A1/en not_active Abandoned
-
2015
- 2015-02-12 CY CY20151100136T patent/CY1116147T1/el unknown
- 2015-04-13 JP JP2015081540A patent/JP2015171365A/ja active Pending
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