DK2317324T3 - A method of identifying an individual at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2 - Google Patents

A method of identifying an individual at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2 Download PDF

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Publication number
DK2317324T3
DK2317324T3 DK10186331.4T DK10186331T DK2317324T3 DK 2317324 T3 DK2317324 T3 DK 2317324T3 DK 10186331 T DK10186331 T DK 10186331T DK 2317324 T3 DK2317324 T3 DK 2317324T3
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Prior art keywords
galectin
rats
heart failure
cardiac
level
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DK10186331.4T
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Danish (da)
English (en)
Inventor
Yigal M Pinto
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Univ Maastricht
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9453Cardioregulators, e.g. antihypotensives, antiarrhythmics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4703Regulators; Modulating activity
    • G01N2333/4704Inhibitors; Supressors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4724Lectins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4728Details alpha-Glycoproteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/321Arterial hypertension
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/325Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrotherapy Devices (AREA)
DK10186331.4T 2003-10-09 2004-09-27 A method of identifying an individual at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2 DK2317324T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03078161A EP1522857A1 (en) 2003-10-09 2003-10-09 Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2
EP04765681A EP1682907B1 (en) 2003-10-09 2004-09-27 Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2

Publications (1)

Publication Number Publication Date
DK2317324T3 true DK2317324T3 (en) 2015-02-16

Family

ID=34306912

Family Applications (2)

Application Number Title Priority Date Filing Date
DK10186331.4T DK2317324T3 (en) 2003-10-09 2004-09-27 A method of identifying an individual at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2
DK04765681.4T DK1682907T3 (da) 2003-10-09 2004-09-27 Fremgangsmåde til identificering af en person med risiko for udvikling af hjerteinsufficiens ved hjælp af bestemmelse af niveauet af galectin-3 eller thrombospondin-2

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK04765681.4T DK1682907T3 (da) 2003-10-09 2004-09-27 Fremgangsmåde til identificering af en person med risiko for udvikling af hjerteinsufficiens ved hjælp af bestemmelse af niveauet af galectin-3 eller thrombospondin-2

Country Status (14)

Country Link
US (5) US7888137B2 (enExample)
EP (4) EP1522857A1 (enExample)
JP (5) JP4840744B2 (enExample)
CN (2) CN1879022B (enExample)
AT (1) ATE532073T1 (enExample)
AU (2) AU2004284496C1 (enExample)
CA (2) CA2842308A1 (enExample)
CY (2) CY1112359T1 (enExample)
DK (2) DK2317324T3 (enExample)
ES (2) ES2530567T3 (enExample)
PL (2) PL1682907T3 (enExample)
PT (2) PT2317324E (enExample)
SI (2) SI1682907T1 (enExample)
WO (1) WO2005040817A1 (enExample)

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Publication number Publication date
US8084276B2 (en) 2011-12-27
JP5580774B2 (ja) 2014-08-27
EP1682907B1 (en) 2011-11-02
EP1682907A1 (en) 2006-07-26
CN102998458B (zh) 2015-07-22
US20120220532A1 (en) 2012-08-30
SI1682907T1 (sl) 2012-03-30
ES2530567T3 (es) 2015-03-03
JP4840744B2 (ja) 2011-12-21
ATE532073T1 (de) 2011-11-15
JP2010279378A (ja) 2010-12-16
EP2919012A1 (en) 2015-09-16
HK1184534A1 (zh) 2014-01-24
AU2004284496C1 (en) 2010-03-04
PL1682907T3 (pl) 2012-03-30
SI2317324T1 (sl) 2015-11-30
AU2004284496A1 (en) 2005-05-06
HK1101426A1 (en) 2007-10-18
ES2377012T3 (es) 2012-03-21
WO2005040817A1 (en) 2005-05-06
AU2009227844A1 (en) 2009-11-26
PL2317324T3 (pl) 2015-10-30
PT1682907E (pt) 2012-02-03
DK1682907T3 (da) 2012-08-13
US20150037353A1 (en) 2015-02-05
EP1522857A1 (en) 2005-04-13
AU2004284496B2 (en) 2009-08-06
CA2842308A1 (en) 2005-05-06
JP5789009B2 (ja) 2015-10-07
CN1879022A (zh) 2006-12-13
CA2542033A1 (en) 2005-05-06
US20130189716A1 (en) 2013-07-25
CA2542033C (en) 2014-04-29
US7888137B2 (en) 2011-02-15
CN102998458A (zh) 2013-03-27
EP2317324A1 (en) 2011-05-04
JP2015171365A (ja) 2015-10-01
EP2317324B1 (en) 2014-11-12
CN1879022B (zh) 2012-10-17
US20110104722A1 (en) 2011-05-05
US20080193954A1 (en) 2008-08-14
JP2011177184A (ja) 2011-09-15
PT2317324E (pt) 2015-02-17
AU2009227844B2 (en) 2012-07-19
CY1112359T1 (el) 2015-12-09
JP2007508527A (ja) 2007-04-05
JP2014115297A (ja) 2014-06-26
CY1116147T1 (el) 2017-02-08

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