JP2007505883A - 2−アルキリデン−19−ノル−ビタミンd誘導体及び副甲状腺ホルモンの組合せを含んでなる医薬組成物及び方法 - Google Patents

2−アルキリデン−19−ノル−ビタミンd誘導体及び副甲状腺ホルモンの組合せを含んでなる医薬組成物及び方法 Download PDF

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JP2007505883A
JP2007505883A JP2006526715A JP2006526715A JP2007505883A JP 2007505883 A JP2007505883 A JP 2007505883A JP 2006526715 A JP2006526715 A JP 2006526715A JP 2006526715 A JP2006526715 A JP 2006526715A JP 2007505883 A JP2007505883 A JP 2007505883A
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vitamin
parathyroid hormone
methylene
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osteoporosis
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トンプソン,デーヴィッド・デュアン
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ファイザー・プロダクツ・インク
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Endocrinology (AREA)
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  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
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  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
JP2006526715A 2003-09-19 2004-09-06 2−アルキリデン−19−ノル−ビタミンd誘導体及び副甲状腺ホルモンの組合せを含んでなる医薬組成物及び方法 Pending JP2007505883A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50450303P 2003-09-19 2003-09-19
PCT/IB2004/002902 WO2005027915A1 (en) 2003-09-19 2004-09-06 Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and parathyroid hormone

Publications (2)

Publication Number Publication Date
JP2007505883A true JP2007505883A (ja) 2007-03-15
JP2007505883A5 JP2007505883A5 (enExample) 2007-11-08

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JP2006526715A Pending JP2007505883A (ja) 2003-09-19 2004-09-06 2−アルキリデン−19−ノル−ビタミンd誘導体及び副甲状腺ホルモンの組合せを含んでなる医薬組成物及び方法

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Country Link
US (1) US20050065088A1 (enExample)
EP (1) EP1667689A1 (enExample)
JP (1) JP2007505883A (enExample)
KR (1) KR20060058133A (enExample)
CN (1) CN1852716A (enExample)
AU (1) AU2004273660B2 (enExample)
BR (1) BRPI0414518A (enExample)
CA (1) CA2539357A1 (enExample)
IL (1) IL174144A0 (enExample)
MX (1) MXPA06003064A (enExample)
NO (1) NO20061236L (enExample)
NZ (1) NZ545803A (enExample)
RU (1) RU2006108557A (enExample)
TW (1) TW200511999A (enExample)
WO (1) WO2005027915A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122533B2 (en) * 1999-11-29 2006-10-17 The United States Of America As Represented By The Department Of Health And Human Services Cosalane compounds and methods for their use
WO2005051323A2 (en) * 2003-11-25 2005-06-09 Wisconsin Alumni Research Foundation Vitamin d analogs for obesity prevention and treatment
WO2005051396A2 (en) * 2003-11-25 2005-06-09 Deltanoid Pharmaceuticals, Inc. Methods for reducing body fat using vitamin d compounds
CA2597624C (en) * 2005-02-11 2012-08-14 Wisconsin Alumni Research Foundation 2-methylene-19-nor-(20s-24s)-1.alpha.,25-dihydroxyvitamin-d2
US7511030B2 (en) * 2005-02-11 2009-03-31 Wisconsin Alumni Research Foundation 2-methylene-19-nor-(20S-24epi)-1α,25-dihydroxyvitamin D2
WO2006105221A1 (en) * 2005-03-29 2006-10-05 Wisconsin Alumni Research Foundation 2-METHYLENE-19-NOR-(23S)-25-DEHYDRO-1α-HYDROXYVITAMIN D3-26,23-LACTONE AND 2-METHYLENE-19-NOR-(23R)-25-DEHYDRO-1α-HYDROXYVITAMIN D3-26,23-LACTONE
US20110237557A1 (en) * 2010-03-23 2011-09-29 Deluca Hector F Diastereomers of 2-methylene-19-nor-22-methyl-1alpha,25-dihydroxyvitamin d3
US8664206B2 (en) 2010-03-23 2014-03-04 Wisconsin Alumni Research Foundation Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3
US8604009B2 (en) 2010-03-23 2013-12-10 Wisconsin Alumni Research Foundation (20S)-2-methylene-19-nor-22-dimethyl-1α,25-dihydroxyvitamin D3 and (20R)-2-methylene-19-nor-22-dimethyl-1α,25-hydroxyvitamin D3
WO2015050160A1 (ja) * 2013-10-03 2015-04-09 国立大学法人大阪大学 副甲状腺ホルモンまたはその誘導体を有効成分とする筋の老化防止用医薬組成物
WO2015064585A1 (ja) * 2013-10-29 2015-05-07 国立大学法人熊本大学 筋疾患の治療または予防のための医薬組成物
KR20200053069A (ko) * 2018-11-07 2020-05-18 주식회사 노브메타파마 시클로-히스프로를 유효성분으로 포함하는 비만 예방 또는 치료용 약제학적 조성물

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07179358A (ja) * 1985-04-04 1995-07-18 General Hospital Corp:The 骨質量増加用医薬複合剤の投与用キット
JP2001504135A (ja) * 1997-03-17 2001-03-27 ウイスコンシン・アルムニ・リサーチ・ファウンデーション 2−アルキリデン−19−ノル−ビタミンd化合物
JP2002523375A (ja) * 1998-08-19 2002-07-30 イーライ・リリー・アンド・カンパニー 骨の靭性、及び、剛性を増し、骨折を減少させる方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5086191A (en) * 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
JP2898882B2 (ja) * 1993-04-05 1999-06-02 ウイスコンシン アラムナイ リサーチ フオンデーシヨン 2−位に置換基を有する19−ノル−ビタミンd3 化合物
EP1295605A3 (en) * 1998-08-19 2003-10-29 Eli Lilly And Company Method of increasing bone toughness and stiffness and reducing fractures

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07179358A (ja) * 1985-04-04 1995-07-18 General Hospital Corp:The 骨質量増加用医薬複合剤の投与用キット
JP2001504135A (ja) * 1997-03-17 2001-03-27 ウイスコンシン・アルムニ・リサーチ・ファウンデーション 2−アルキリデン−19−ノル−ビタミンd化合物
JP2002523375A (ja) * 1998-08-19 2002-07-30 イーライ・リリー・アンド・カンパニー 骨の靭性、及び、剛性を増し、骨折を減少させる方法

Also Published As

Publication number Publication date
IL174144A0 (en) 2006-08-01
AU2004273660B2 (en) 2010-08-19
AU2004273660A1 (en) 2005-03-31
CA2539357A1 (en) 2005-03-31
MXPA06003064A (es) 2006-05-31
CN1852716A (zh) 2006-10-25
WO2005027915A1 (en) 2005-03-31
NZ545803A (en) 2008-03-28
KR20060058133A (ko) 2006-05-29
TW200511999A (en) 2005-04-01
RU2006108557A (ru) 2007-09-27
US20050065088A1 (en) 2005-03-24
NO20061236L (no) 2006-06-15
EP1667689A1 (en) 2006-06-14
BRPI0414518A (pt) 2006-11-07

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