JP2007504259A - エポチロンでの癌処置 - Google Patents
エポチロンでの癌処置 Download PDFInfo
- Publication number
- JP2007504259A JP2007504259A JP2006525704A JP2006525704A JP2007504259A JP 2007504259 A JP2007504259 A JP 2007504259A JP 2006525704 A JP2006525704 A JP 2006525704A JP 2006525704 A JP2006525704 A JP 2006525704A JP 2007504259 A JP2007504259 A JP 2007504259A
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- Prior art keywords
- epothilone
- pharmaceutical formulation
- treatment
- tumor
- manufacture
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49954803P | 2003-09-02 | 2003-09-02 | |
| PCT/EP2004/009737 WO2005020989A1 (en) | 2003-09-02 | 2004-09-01 | Cancer treatment with epothilones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007504259A true JP2007504259A (ja) | 2007-03-01 |
| JP2007504259A5 JP2007504259A5 (https=) | 2007-10-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006525704A Pending JP2007504259A (ja) | 2003-09-02 | 2004-09-01 | エポチロンでの癌処置 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20060235059A1 (https=) |
| EP (1) | EP1663214A1 (https=) |
| JP (1) | JP2007504259A (https=) |
| CN (1) | CN1870995A (https=) |
| AU (1) | AU2004268377B2 (https=) |
| BR (1) | BRPI0414043A (https=) |
| CA (1) | CA2537057A1 (https=) |
| MX (1) | MXPA06002393A (https=) |
| WO (1) | WO2005020989A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1640004A1 (en) * | 2004-09-24 | 2006-03-29 | Schering Aktiengesellschaft | Use of epothilones in the treatment of bone metastases and bone tumors or cancers |
| CN100384419C (zh) * | 2005-12-02 | 2008-04-30 | 菏泽睿鹰制药集团有限公司 | 一种埃坡霉素缓释植入组合物及应用 |
| EA020954B1 (ru) | 2008-06-16 | 2015-03-31 | Бинд Терапьютикс, Инк. | Загруженные лекарственным средством полимерные наночастицы, фармацевтическая композиция и способ лечения рака |
| WO2010005726A2 (en) | 2008-06-16 | 2010-01-14 | Bind Biosciences Inc. | Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same |
| US8318211B2 (en) | 2008-06-16 | 2012-11-27 | Bind Biosciences, Inc. | Therapeutic polymeric nanoparticles comprising vinca alkaloids and methods of making and using same |
| US8563041B2 (en) | 2008-12-12 | 2013-10-22 | Bind Therapeutics, Inc. | Therapeutic particles suitable for parenteral administration and methods of making and using same |
| JP2012512175A (ja) | 2008-12-15 | 2012-05-31 | バインド バイオサイエンシズ インコーポレイテッド | 治療薬を徐放するための長時間循環性ナノ粒子 |
| DK2509634T3 (en) | 2009-12-11 | 2019-04-23 | Pfizer | Stable formulations for lyophilization of therapeutic particles |
| EP2515942B1 (en) | 2009-12-15 | 2020-02-12 | Pfizer Inc. | Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers |
| WO2011084521A2 (en) * | 2009-12-15 | 2011-07-14 | Bind Biosciences, Inc. | Therapeutic polymeric nanoparticles comprising epothilone and methods of making and using same |
| WO2014043618A1 (en) | 2012-09-17 | 2014-03-20 | Bind Therapeutics, Inc. | Process for preparing therapeutic nanoparticles |
| PE20170312A1 (es) | 2014-03-14 | 2017-03-30 | Pfizer | Nanoparticulas terapeuticas que comprenden un agente terapeutico, y metodos para su elaboracion y uso |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4820269A (en) * | 1983-03-07 | 1989-04-11 | Vanderbilt University | Mixer apparatus for controlling intravenous drug infusion |
| US5968972A (en) * | 1995-10-26 | 1999-10-19 | Baker Norton Pharmaceuticals, Inc. | Method for increasing the oral bioactivity of pharmaceutical agents |
| US6302838B1 (en) * | 1998-02-25 | 2001-10-16 | Novartis Ag | Cancer treatment with epothilones |
| FR2775187B1 (fr) * | 1998-02-25 | 2003-02-21 | Novartis Ag | Utilisation de l'epothilone b pour la fabrication d'une preparation pharmaceutique antiproliferative et d'une composition comprenant l'epothilone b comme agent antiproliferatif in vivo |
| ES2304240T3 (es) * | 2001-01-25 | 2008-10-01 | Bristol-Myers Squibb Company | Procedimientos para la preparacion de preparaciones farmaceuticas que contienen analogos de epotilona para el tratamiento de cancer. |
| IL157443A0 (en) * | 2001-03-14 | 2004-03-28 | Bristol Myers Squibb Co | Pharmaceutical compositions for the treatment of cancer including an epothilone analog and a chemotherapeutic agent |
| TWI287986B (en) * | 2001-12-13 | 2007-10-11 | Novartis Ag | Use of Epothilones for the treatment of the carcinoid syndrome |
| MXPA04006822A (es) * | 2002-01-14 | 2004-12-08 | Novartis Ag | Combinaciones que comprenden epotilonas y anti-metabolitos. |
| EP1503756B1 (en) * | 2002-05-01 | 2009-08-12 | Novartis AG | Epothilone derivative for the treatment of hepatoma and other cancer diseases |
| CN101389334A (zh) * | 2002-05-20 | 2009-03-18 | 高山生物科学股份有限公司 | 埃坡霉素d的给药方法 |
| BR0313198A (pt) * | 2002-08-02 | 2005-07-12 | Novartis Ag | Derivados de epotilona |
| BR0317150A (pt) * | 2002-12-09 | 2005-11-01 | Novartis Ag | Estabilizadores de microtúbulos em stents para o tratamento de estenose |
| BRPI0412000A (pt) * | 2003-06-27 | 2006-08-15 | Novartis Ag | tratamento de cáncer com epotilonas |
-
2004
- 2004-09-01 AU AU2004268377A patent/AU2004268377B2/en not_active Ceased
- 2004-09-01 CN CNA2004800313316A patent/CN1870995A/zh active Pending
- 2004-09-01 JP JP2006525704A patent/JP2007504259A/ja active Pending
- 2004-09-01 MX MXPA06002393A patent/MXPA06002393A/es not_active Application Discontinuation
- 2004-09-01 WO PCT/EP2004/009737 patent/WO2005020989A1/en not_active Ceased
- 2004-09-01 EP EP04764699A patent/EP1663214A1/en not_active Ceased
- 2004-09-01 CA CA002537057A patent/CA2537057A1/en not_active Abandoned
- 2004-09-01 BR BRPI0414043-5A patent/BRPI0414043A/pt not_active IP Right Cessation
- 2004-09-01 US US10/570,850 patent/US20060235059A1/en not_active Abandoned
-
2008
- 2008-11-12 US US12/269,293 patent/US20090069394A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20060235059A1 (en) | 2006-10-19 |
| MXPA06002393A (es) | 2006-06-20 |
| EP1663214A1 (en) | 2006-06-07 |
| AU2004268377B2 (en) | 2008-06-26 |
| CA2537057A1 (en) | 2005-03-10 |
| US20090069394A1 (en) | 2009-03-12 |
| CN1870995A (zh) | 2006-11-29 |
| BRPI0414043A (pt) | 2006-10-24 |
| WO2005020989A1 (en) | 2005-03-10 |
| AU2004268377A1 (en) | 2005-03-10 |
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