JP2007503847A5 - - Google Patents
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- Publication number
- JP2007503847A5 JP2007503847A5 JP2006532294A JP2006532294A JP2007503847A5 JP 2007503847 A5 JP2007503847 A5 JP 2007503847A5 JP 2006532294 A JP2006532294 A JP 2006532294A JP 2006532294 A JP2006532294 A JP 2006532294A JP 2007503847 A5 JP2007503847 A5 JP 2007503847A5
- Authority
- JP
- Japan
- Prior art keywords
- poxvirus
- insertion site
- open reading
- foreign gene
- reading frames
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000003780 insertion Methods 0.000 claims 4
- 230000037431 insertion Effects 0.000 claims 4
- 108700026244 Open Reading Frames Proteins 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 108091029795 Intergenic region Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44859103P | 2003-02-20 | 2003-02-20 | |
| US60/448,591 | 2003-02-20 | ||
| PCT/US2004/005077 WO2005048957A2 (en) | 2003-02-20 | 2004-02-20 | Novel insertion sites in pox vectors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010120319A Division JP5053420B2 (ja) | 2003-02-20 | 2010-05-26 | ポックスベクターにおける新規の挿入部位 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007503847A JP2007503847A (ja) | 2007-03-01 |
| JP2007503847A5 true JP2007503847A5 (enExample) | 2010-07-15 |
| JP5052893B2 JP5052893B2 (ja) | 2012-10-17 |
Family
ID=34619255
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006532294A Expired - Lifetime JP5052893B2 (ja) | 2003-02-20 | 2004-02-20 | ポックスベクターにおける新規の挿入部位 |
| JP2010120319A Expired - Lifetime JP5053420B2 (ja) | 2003-02-20 | 2010-05-26 | ポックスベクターにおける新規の挿入部位 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010120319A Expired - Lifetime JP5053420B2 (ja) | 2003-02-20 | 2010-05-26 | ポックスベクターにおける新規の挿入部位 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7638134B2 (enExample) |
| EP (2) | EP2363493B1 (enExample) |
| JP (2) | JP5052893B2 (enExample) |
| AU (1) | AU2004291024B2 (enExample) |
| CA (1) | CA2515890C (enExample) |
| WO (1) | WO2005048957A2 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9133478B2 (en) † | 2006-08-25 | 2015-09-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Modified vaccinia Ankara (MVA) virus recombinants comprising heterologous coding sequences inserted into the intergenic regions between essential genes |
| EP2426142A3 (en) | 2006-10-16 | 2012-06-13 | Genelux Corporation | Modified vaccinia virus strains for use in a diagnostic and therapeutic method |
| AU2009212787B2 (en) * | 2007-04-27 | 2015-03-26 | Bavarian Nordic A/S | Induction of dendritic cell development with macrophage-colony stimulating factor (M-CSF) |
| CA2676808C (en) * | 2007-04-27 | 2016-08-02 | Bavarian Nordic A/S | Induction of dendritic cell development with macrophage-colony stimulating factor (m-csf) |
| US8268327B2 (en) * | 2007-04-27 | 2012-09-18 | Bavarian Nordic A/S | Immediate protection against pathogens via MVA |
| US8691502B2 (en) | 2008-10-31 | 2014-04-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
| GB201006405D0 (en) | 2010-04-16 | 2010-06-02 | Isis Innovation | Poxvirus expression system |
| US10138271B2 (en) | 2012-01-03 | 2018-11-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Native and agonist CTL epitopes of the MUC1 tumor antigen |
| MX2015000789A (es) | 2012-07-19 | 2015-05-07 | Zoetis Llc | Composiciones de virus de la gripe bovina. |
| AU2013295770A1 (en) | 2012-07-27 | 2015-01-29 | Zoetis Services Llc | Tick toxin compositions |
| US9732325B2 (en) | 2012-09-28 | 2017-08-15 | Probiogen Ag | MVA virus and uses thereof |
| CA3205348A1 (en) | 2013-10-23 | 2015-04-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Hla-a24 agonist epitopes of muc1-c oncoprotein and compositions and methods of use |
| EP3244919A4 (en) | 2015-01-12 | 2018-06-27 | Geovax, Inc. | Compositions and methods for generating an immune response to a hemorrhagic fever virus |
| KR20160140075A (ko) * | 2015-05-29 | 2016-12-07 | 코오롱생명과학 주식회사 | 폭스바이러스 유래 프로모터 및 이를 포함하는 벡터 |
| KR102565284B1 (ko) | 2015-07-31 | 2023-08-08 | 버베리안 노딕 에이/에스 | 폭스바이러스에서 발현을 증강하기 위한 프로모터 |
| CN116196403A (zh) | 2015-08-03 | 2023-06-02 | 美国卫生和人力服务部 | Brachyury缺失突变体、编码该缺失突变体的非酵母载体及其用途 |
| CN108135989B (zh) | 2015-08-14 | 2022-08-09 | 硕腾服务有限责任公司 | 牛支原体组合物 |
| PL3402802T3 (pl) | 2016-01-08 | 2023-06-05 | Geovax, Inc. | Kompozycje i sposoby generowania odpowiedzi immunologicznej względem antygenu powiązanego z guzem nowotworowym |
| WO2017136419A1 (en) | 2016-02-03 | 2017-08-10 | Geovax Inc. | Compositions and methods for generating an immune response to a flavivirus |
| ES2883720T3 (es) | 2016-11-07 | 2021-12-09 | Us Health | Desarrollo de epítopos agonistas del virus del papiloma humano |
| US11311612B2 (en) | 2017-09-19 | 2022-04-26 | Geovax, Inc. | Compositions and methods for generating an immune response to treat or prevent malaria |
| CA3119736A1 (en) | 2018-11-14 | 2020-05-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Tp5, a peptide inhibitor of aberrant and hyperactive cdk5/p25 as treatment for cancer |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| EP4061405A1 (en) | 2019-11-18 | 2022-09-28 | Janssen Biotech, Inc. | Vaccines based on mutant calr and jak2 and their uses |
| WO2021150694A1 (en) | 2020-01-21 | 2021-07-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human immunogenic epitopes of hemo and hhla2 human endogenous retroviruses (hervs) |
| WO2021150713A2 (en) | 2020-01-21 | 2021-07-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human immunogenic epitopes of h, k, and e human endogenous retroviruses (hervs) |
| US20230097513A1 (en) * | 2020-02-03 | 2023-03-30 | City Of Hope | Poxvirus-based vectors produced by natural or synthetic dna and uses thereof |
| TW202144389A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在多發性骨髓瘤中表現之新抗原及其用途 |
| TW202144388A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在卵巢癌中表現之新抗原及其用途 |
| WO2021209897A1 (en) | 2020-04-13 | 2021-10-21 | Janssen Biotech, Inc. | Psma and steap1 vaccines and their uses |
| AU2021267163B2 (en) | 2020-05-06 | 2024-05-23 | Vaccinex, Inc. | Integral membrane protein display on poxvirus extracellular enveloped virions |
| EP4175721A1 (en) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| EP4175664A2 (en) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| US20230035403A1 (en) | 2020-07-06 | 2023-02-02 | Janssen Biotech, Inc. | Method For Determining Responsiveness To Prostate Cancer Treatment |
| KR20250048615A (ko) | 2022-07-08 | 2025-04-09 | 바이로미슬, 인크. | 종양용해 백시니아 바이러스 및 재조합 바이러스 및 그의 사용 방법 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364773A (en) | 1991-03-07 | 1994-11-15 | Virogenetics Corporation | Genetically engineered vaccine strain |
| US4514506A (en) | 1982-02-23 | 1985-04-30 | The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services | Method for the identification and purification of human lung tumor-associated antigens (hLTAA) and clinical detection and determination of these antigens |
| CA1340203C (en) | 1987-09-16 | 1998-12-15 | Noboru Yanagida | Recombinant apivoxvirus |
| FR2632863B2 (fr) * | 1987-10-29 | 1990-08-31 | Transgene Sa | Virus du fowlpox recombinant et vaccins derives de ces virus |
| CA1341245C (en) * | 1988-01-12 | 2001-06-05 | F. Hoffmann-La Roche Ag | Recombinant vaccinia virus mva |
| US5093258A (en) | 1988-08-26 | 1992-03-03 | Therion Biologics Corporation | Recombinant fowlpox virus and recombination vector |
| BE1004877A3 (fr) * | 1991-05-27 | 1993-02-16 | Solvay | Virus de l'avipox recombinant, culture de cellules infectees par ce virus et vaccins pour la volaille derives de ce virus. |
| DE69133333T2 (de) * | 1991-08-26 | 2004-07-29 | Baxter Healthcare S.A. | Ein intaktes FPV-tk-Gen enthaltender rekombinanter Virus der Vogelpocken |
| US5445953A (en) * | 1991-08-26 | 1995-08-29 | Immuno Aktiengesellschaft | Direct molecular cloning of a modified poxvirus genome |
| EP0651805B1 (en) | 1992-07-17 | 2006-12-13 | Dana Farber Cancer Institute | Method of intracellular binding of target molecules |
| US5851829A (en) | 1993-07-16 | 1998-12-22 | Dana-Farber Cancer Institute | Method of intracellular binding of target molecules |
| US5656465A (en) | 1994-05-04 | 1997-08-12 | Therion Biologics Corporation | Methods of in vivo gene delivery |
| US6045802A (en) | 1994-10-03 | 2000-04-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule |
| UA68327C2 (en) | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
| US5990091A (en) * | 1997-03-12 | 1999-11-23 | Virogenetics Corporation | Vectors having enhanced expression, and methods of making and uses thereof |
| AUPP380598A0 (en) * | 1998-05-29 | 1998-06-25 | Commonwealth Scientific And Industrial Research Organisation | Genetically manipulated entomopoxvirus |
| US6682742B1 (en) * | 1999-05-28 | 2004-01-27 | Gsf Forschungszentrum Fur Unwelt Und Gesundheit Gmbh | Vector for integration of heterologous sequences into poxviral genomes |
| NZ521270A (en) | 2000-03-14 | 2003-06-30 | Bavarian Nordic As | Altered strain of the Modified Vaccinia virus Ankara (MVA) for growth in a continuous vero cell line |
| CU23235A1 (es) * | 2001-02-28 | 2007-09-26 | Ct Ingenieria Genetica Biotech | POXVIRUS RECOMBINANTES PARA PROTEINAS QUIMéRICAS DEL VIRUS DE LA INMUNODEFICIENCIA HUMANA Y SU APLICACION EN LA TERAPéUTICA Y LA PREVENCION DEL SIDA |
| EP2253709B1 (en) * | 2002-05-16 | 2018-04-11 | Bavarian Nordic A/S | Recombinant poxvirus expressing homologous genes inserted into the poxviral genome |
| WO2004098534A2 (en) | 2003-02-24 | 2004-11-18 | Therion Biologics Corporation | Methods for delivering angiogenic modulators using pox viruses |
-
2004
- 2004-02-20 WO PCT/US2004/005077 patent/WO2005048957A2/en not_active Ceased
- 2004-02-20 EP EP11158563A patent/EP2363493B1/en not_active Expired - Lifetime
- 2004-02-20 AU AU2004291024A patent/AU2004291024B2/en not_active Expired
- 2004-02-20 CA CA2515890A patent/CA2515890C/en not_active Expired - Lifetime
- 2004-02-20 JP JP2006532294A patent/JP5052893B2/ja not_active Expired - Lifetime
- 2004-02-20 US US10/543,944 patent/US7638134B2/en not_active Expired - Lifetime
- 2004-02-20 EP EP04817689A patent/EP1601333B1/en not_active Expired - Lifetime
-
2009
- 2009-12-16 US US12/639,781 patent/US20100136056A1/en not_active Abandoned
-
2010
- 2010-05-26 JP JP2010120319A patent/JP5053420B2/ja not_active Expired - Lifetime
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