JP2007500730A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007500730A5 JP2007500730A5 JP2006522145A JP2006522145A JP2007500730A5 JP 2007500730 A5 JP2007500730 A5 JP 2007500730A5 JP 2006522145 A JP2006522145 A JP 2006522145A JP 2006522145 A JP2006522145 A JP 2006522145A JP 2007500730 A5 JP2007500730 A5 JP 2007500730A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- mammal
- formula
- methoxy
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CN1Cc2cc(*)c(*)cc2CC1 Chemical compound CN1Cc2cc(*)c(*)cc2CC1 0.000 description 1
- LQOYFQQIZFEVDY-UHFFFAOYSA-N COc(c(cccc1)c1c(Br)c1)c1C(NCCN(CC1)Cc2c1cccc2)=O Chemical compound COc(c(cccc1)c1c(Br)c1)c1C(NCCN(CC1)Cc2c1cccc2)=O LQOYFQQIZFEVDY-UHFFFAOYSA-N 0.000 description 1
- UNYNHWPKQAKANT-UHFFFAOYSA-N COc1cc(CCN(CCCCNC(c2cc(Br)cc(OC)c2OC)=O)C2)c2cc1OC Chemical compound COc1cc(CCN(CCCCNC(c2cc(Br)cc(OC)c2OC)=O)C2)c2cc1OC UNYNHWPKQAKANT-UHFFFAOYSA-N 0.000 description 1
- XNWMOTJGVMWJLH-UHFFFAOYSA-N Cc(cc1)cc(C(NCCCCN(CC2)Cc(cc3C=O)c2cc3OC)=O)c1OCCF Chemical compound Cc(cc1)cc(C(NCCCCN(CC2)Cc(cc3C=O)c2cc3OC)=O)c1OCCF XNWMOTJGVMWJLH-UHFFFAOYSA-N 0.000 description 1
- KOEMMHBJOHMMBF-UHFFFAOYSA-N Cc(cc1C(NCCCCN(CCc2c3)Cc2cc(OC)c3OC)=O)ccc1OC Chemical compound Cc(cc1C(NCCCCN(CCc2c3)Cc2cc(OC)c3OC)=O)ccc1OC KOEMMHBJOHMMBF-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49158203P | 2003-07-31 | 2003-07-31 | |
| PCT/US2004/025304 WO2005048810A2 (en) | 2003-07-31 | 2004-07-30 | Sigma-2 receptor radiotracers for imaging the proliferative status of solid tumors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007500730A JP2007500730A (ja) | 2007-01-18 |
| JP2007500730A5 true JP2007500730A5 (enExample) | 2007-09-13 |
Family
ID=34619287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006522145A Pending JP2007500730A (ja) | 2003-07-31 | 2004-07-30 | 固形癌の増殖状態を画像化するためのシグマ−２受容体ラジオトレーサー |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US7390902B2 (enExample) |
| EP (1) | EP1660137A4 (enExample) |
| JP (1) | JP2007500730A (enExample) |
| WO (1) | WO2005048810A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7390902B2 (en) * | 2003-07-31 | 2008-06-24 | Washington University | Sigma-2 receptor radiotracers for imaging the proliferative status of solid tumors |
| US7659400B2 (en) * | 2003-07-31 | 2010-02-09 | Washington University | Radiolabelled benzamide analogues, their synthesis and use in diagnostic imaging |
| EP1904443A1 (en) * | 2005-07-12 | 2008-04-02 | Bayer Cropscience Sa | New benzoheterocyclylethylbenzamide derivatives |
| KR101608755B1 (ko) | 2005-11-29 | 2016-04-04 | 니혼 메디피직스 가부시키가이샤 | 방사성 할로겐 표식 유기 화합물의 전구체 화합물 |
| US8143222B2 (en) * | 2007-10-22 | 2012-03-27 | Washington University | Modular platform for targeted therapeutic delivery |
| US20090324496A1 (en) * | 2008-06-27 | 2009-12-31 | Tang I-Chung | Radioactive material for inhibiting cancer and preparation method thereof |
| US8506927B2 (en) | 2011-01-05 | 2013-08-13 | Washington University | Pegylated fluorobenzamide analogues, their synthesis and use in diagnostic imaging |
| GB201415573D0 (en) | 2014-09-03 | 2014-10-15 | Cancer Therapeutics Crc Pty Ltd | Compounds |
| US10494376B2 (en) | 2014-09-03 | 2019-12-03 | Ctxt Pty. Ltd. | Tetrahydroisoquinoline derived PRMT5-inhibitors |
| WO2016034671A1 (en) | 2014-09-03 | 2016-03-10 | Ctxt Pty Ltd | Aminoindane-, aminotetrahydronaphthalene- and aminobenzocyclobutane-derived prmt5-inhibitors |
| WO2016178852A1 (en) * | 2015-05-04 | 2016-11-10 | The Trustees Of The University Of Pennsylvania | 211-astatine containing radiotherapeutics for the treatment of cancer |
| GB201604030D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604027D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604031D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604029D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604022D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604020D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| CN112898278B (zh) * | 2019-11-19 | 2022-05-13 | 广东医科大学 | Sigma-2荧光配体的制备及应用 |
| EP4202425A1 (en) * | 2021-12-23 | 2023-06-28 | King Faisal Specialist Hospital & Research Centre | Phantom for testing drug-cell interaction |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4197243A (en) * | 1975-04-02 | 1980-04-08 | Yamanouchi Pharmaceutical Co., Ltd. | N-1-Benzyl-3-pyrrolidinyl-4-dimethylamino benzamide derivatives |
| US5294621A (en) * | 1992-10-07 | 1994-03-15 | Ortho Pharmaceutical Corporation | Thieno tetrahydropyridines useful as class III antiarrhythmic agents |
| US5911970A (en) * | 1993-05-06 | 1999-06-15 | Research Corporation Technologies, Inc. | Methods for cancer imaging and therapy using benzamine compounds |
| DE69739869D1 (de) * | 1996-03-20 | 2010-06-17 | Univ Wake Forest Health Sciences | Sigma-2 rezeptoren als biomarkierer der tumorzellenproliferation |
| TR199802284T2 (xx) | 1996-05-11 | 2000-05-22 | Smithkline Beecham P.L.C. | Dopamin D3 resept�rlerinin mod�lat�rleri olarak tetrahidroizokuinolin t�revleri. |
| GB9717576D0 (en) * | 1997-08-19 | 1997-10-22 | Xenova Ltd | Pharmaceutical compounds |
| GB9708694D0 (en) * | 1997-04-30 | 1997-06-18 | Smithkline Beecham Plc | Compounds |
| US7390902B2 (en) * | 2003-07-31 | 2008-06-24 | Washington University | Sigma-2 receptor radiotracers for imaging the proliferative status of solid tumors |
| US7612085B2 (en) | 2006-07-11 | 2009-11-03 | Washington University | Sigma 2 receptor ligands and therapeutic uses therefor |
-
2004
- 2004-07-30 US US10/903,771 patent/US7390902B2/en not_active Expired - Fee Related
- 2004-07-30 WO PCT/US2004/025304 patent/WO2005048810A2/en not_active Ceased
- 2004-07-30 JP JP2006522145A patent/JP2007500730A/ja active Pending
- 2004-07-30 EP EP04817745A patent/EP1660137A4/en not_active Withdrawn
-
2008
- 2008-03-08 US US12/044,952 patent/US7612206B2/en not_active Expired - Fee Related
-
2009
- 2009-08-28 US US12/550,220 patent/US7893266B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2007500730A5 (enExample) | ||
| KR102527562B1 (ko) | 영상화제의 합성 및 사용을 위한 조성물, 방법 및 시스템 | |
| Kung et al. | Synthesis and biodistribution of neutral lipid-soluble Tc-99m complexes that cross the blood-brain barrier | |
| TWI549692B (zh) | 使心臟神經分布顯像之配位體 | |
| KR101155403B1 (ko) | 플루오린이 도입된 벤조타이아졸 유도체, 이의 제조방법 및 이를 이용한 알츠하이머 질환 진단용 영상화제 | |
| CN101555232B (zh) | 氟-18标记哒嗪酮类化合物及制备方法和应用 | |
| US8435489B2 (en) | Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma | |
| JP2010529088A5 (enExample) | ||
| EP2388017B1 (en) | Catalytic radiofluorination | |
| US8900550B2 (en) | Catalytic radiofluorination | |
| CN1950329B (zh) | 放射性酪氨酸衍生物、其制造方法、其使用、正电子成像用标识剂和肿瘤的恶性度评价药剂 | |
| JP2005523941A5 (enExample) | ||
| JP2009538894A5 (enExample) | ||
| JP2012504581A5 (enExample) | ||
| US8168786B2 (en) | Radiolabeled compounds and uses thereof | |
| US5407658A (en) | Analogs of cytochalasin B as radiopharmaceuticals for nuclear imaging of trans-membrane glucose transport | |
| JP2013507345A5 (enExample) | ||
| US20170334804A1 (en) | F-18 labeled tracer and methods of manufacture | |
| CN101293864B (zh) | 一种与脑Aβ斑块具有亲和力的化合物及其制备方法和应用 | |
| CN1046857C (zh) | 硫酸三异腈亚铜配合物及其制备方法 | |
| US20020099184A1 (en) | 4-Haloethenyphenyl tropane:serotonin transporter imaging agents | |
| JP5209299B2 (ja) | 放射性ハロゲン化ベンズアミド誘導体および腫瘍診断と腫瘍療法におけるそれらの利用 | |
| CN101486708B (zh) | 一类锝-99m标记的肿瘤乏氧显像剂及其制备方法和应用 | |
| CN101486707A (zh) | 2-甲基-5-硝基咪唑类化合物及其制备方法和应用 | |
| CN119841813A (zh) | 靶向成纤维细胞活化蛋白的化合物及其用途 |