JP2007186470A5 - - Google Patents

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Publication number
JP2007186470A5
JP2007186470A5 JP2006007331A JP2006007331A JP2007186470A5 JP 2007186470 A5 JP2007186470 A5 JP 2007186470A5 JP 2006007331 A JP2006007331 A JP 2006007331A JP 2006007331 A JP2006007331 A JP 2006007331A JP 2007186470 A5 JP2007186470 A5 JP 2007186470A5
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JP
Japan
Prior art keywords
compression
preparation according
mass
bulk density
molded preparation
Prior art date
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Application number
JP2006007331A
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Japanese (ja)
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JP5021210B2 (en
JP2007186470A (en
Filing date
Publication date
Priority claimed from JP2006007331A external-priority patent/JP5021210B2/en
Priority to JP2006007331A priority Critical patent/JP5021210B2/en
Application filed filed Critical
Priority to TW095139056A priority patent/TWI414287B/en
Priority to KR1020060108839A priority patent/KR101364561B1/en
Priority to CN2006101564628A priority patent/CN101002765B/en
Publication of JP2007186470A publication Critical patent/JP2007186470A/en
Priority to HK07112670.5A priority patent/HK1104234A1/en
Publication of JP2007186470A5 publication Critical patent/JP2007186470A5/ja
Publication of JP5021210B2 publication Critical patent/JP5021210B2/en
Application granted granted Critical
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Anticipated expiration legal-status Critical

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Claims (7)

Ｌ−システイン若しくはその塩をＬ−システインに換算して２０〜４０質量％、アスコルビン酸若しくはその塩をアスコルビン酸に換算して３０〜７０質量％、複数の結晶セルロースを合計で７.５〜２５質量％および高膨潤性高分子を１〜２０質量％含有することを特徴とする圧縮成型製剤。   L-cysteine or a salt thereof is converted into L-cysteine, 20 to 40% by mass, ascorbic acid or a salt thereof is converted into ascorbic acid, 30 to 70% by mass, and a plurality of crystalline celluloses are added in a total of 7.5 to 25. A compression-molded preparation comprising 1 to 20% by mass of a mass% and a highly swellable polymer. 複数の結晶セルロースの一方が、嵩密度０.３ｇ/ｃｍ３以上の結晶セルロースであり、他方が嵩密度０.３ｇ/ｃｍ３未満の結晶セルロースである請求項第１項記載の圧縮成型製剤。 The compression-molded preparation according to claim 1, wherein one of the plurality of crystalline celluloses is crystalline cellulose having a bulk density of 0.3 g / cm 3 or more, and the other is crystalline cellulose having a bulk density of less than 0.3 g / cm 3 . 嵩密度０.３ｇ/ｃｍ３以上の結晶セルロースと、嵩密度０.３ｇ/ｃｍ３未満の結晶セルロースとの比率が、８：１〜１：４である請求項第１項または第２項記載の圧縮成型製剤。 The ratio between crystalline cellulose having a bulk density of 0.3 g / cm 3 or more and crystalline cellulose having a bulk density of less than 0.3 g / cm 3 is 8: 1 to 1: 4. Compression molding formulation. 高膨潤性高分子が、低置換度ヒドロキシプロピルセルロース、クロスカルメロースナトリウムまたはクロスポピドンから選ばれるものの１種または２種以上である請求項第１ないし３のいずれかの項記載の圧縮成型製剤。   The compression-molded preparation according to any one of claims 1 to 3, wherein the highly swellable polymer is one or more selected from low-substituted hydroxypropylcellulose, croscarmellose sodium or crospovidone. 更に、水溶性高分子、軽質無水ケイ酸、糖類、糖アルコール、澱粉、タルクおよびステアリン酸マグネシウムから選ばれる成分の１種または２種以上を含有することを特徴とする請求項第１ないし４のいずれかの項記載の圧縮成型製剤。   Furthermore, 1 type or 2 types or more of the component chosen from water-soluble polymer, a light silicic acid anhydride, saccharides, sugar alcohol, starch, talc, and magnesium stearate are contained, The 1st thru | or 4 characterized by the above-mentioned. A compression-molded preparation according to any one of the items. 更に製剤表面を水溶性フィルム基剤により被覆する請求項第１ないし５のいずれかの項記載の圧縮成型製剤。 The compression-molded preparation according to any one of claims 1 to 5, wherein the preparation surface is further coated with a water-soluble film base. 更に製剤表面を糖衣により被覆する請求項第１ないし６のいずれかの項記載の圧縮成型製剤。 The compression-molded preparation according to any one of claims 1 to 6, wherein the preparation surface is further coated with sugar coating.
JP2006007331A 2006-01-16 2006-01-16 Compression molding Active JP5021210B2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2006007331A JP5021210B2 (en) 2006-01-16 2006-01-16 Compression molding
TW095139056A TWI414287B (en) 2006-01-16 2006-10-23 Compression molded preparation
KR1020060108839A KR101364561B1 (en) 2006-01-16 2006-11-06 Compression molded preparation
CN2006101564628A CN101002765B (en) 2006-01-16 2006-12-31 Compressed formed preparation
HK07112670.5A HK1104234A1 (en) 2006-01-16 2007-11-20 Compression molded preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006007331A JP5021210B2 (en) 2006-01-16 2006-01-16 Compression molding

Publications (3)

Publication Number Publication Date
JP2007186470A JP2007186470A (en) 2007-07-26
JP2007186470A5 true JP2007186470A5 (en) 2009-02-05
JP5021210B2 JP5021210B2 (en) 2012-09-05

Family

ID=38341887

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006007331A Active JP5021210B2 (en) 2006-01-16 2006-01-16 Compression molding

Country Status (5)

Country Link
JP (1) JP5021210B2 (en)
KR (1) KR101364561B1 (en)
CN (1) CN101002765B (en)
HK (1) HK1104234A1 (en)
TW (1) TWI414287B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2407166B1 (en) 2009-03-13 2013-08-21 Toyama Chemical Co., Ltd. Tablet and granulated powder containing 6-fluoro-3-hydroxy-2-pyrazinecarboxamide
JP5733930B2 (en) * 2009-09-09 2015-06-10 武田薬品工業株式会社 Solid preparation
SI2946780T1 (en) * 2013-01-15 2017-05-31 Fujifilm Corporation Tablet containing 5-hydroxy-1h-imidazole-4-carboxamide
JP6327237B2 (en) * 2014-12-05 2018-05-23 大正製薬株式会社 Solid composition
JP7330716B2 (en) * 2019-02-21 2023-08-22 アサヒグループ食品株式会社 Method for suppressing discoloration of composition containing amino acid or its salt and vitamin C, powder composition, granules, and tablet
JP6676816B1 (en) * 2019-05-31 2020-04-08 シオノギヘルスケア株式会社 L-cysteine-containing vitamin C-rich compression molded preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001322927A (en) * 2000-05-12 2001-11-20 Shin Etsu Chem Co Ltd Solid preparation including hydroxypropyl cellulose of low substitution degree and method for preparation of the same
JP2002179559A (en) * 2000-10-06 2002-06-26 Takeda Chem Ind Ltd Thin-layer sugar-coated tablet and method for producing the same
JP2004026786A (en) * 2002-05-10 2004-01-29 Takeda Chem Ind Ltd Vitamin preparation
CN1593411A (en) * 2004-01-15 2005-03-16 范敏华 Speckle removing pharmaceutical composition

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