JP2007297460A5 - - Google Patents
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- JP2007297460A5 JP2007297460A5 JP2006125139A JP2006125139A JP2007297460A5 JP 2007297460 A5 JP2007297460 A5 JP 2007297460A5 JP 2006125139 A JP2006125139 A JP 2006125139A JP 2006125139 A JP2006125139 A JP 2006125139A JP 2007297460 A5 JP2007297460 A5 JP 2007297460A5
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- sample
- intrinsic viscosity
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- formula
- sample concentration
- Prior art date
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- 235000019749 Dry matter Nutrition 0.000 description 1
- 238000004164 analytical calibration Methods 0.000 description 1
- 238000011088 calibration curve Methods 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- MAKUBRYLFHZREJ-JWBQXVCJSA-M sodium;(2S,3S,4R,5R,6R)-3-[(2S,3R,5S,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylate Chemical group [Na+].CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C([O-])=O)O[C@@H](O)[C@H](O)[C@H]1O MAKUBRYLFHZREJ-JWBQXVCJSA-M 0.000 description 1
Description
次いで、各試料溶液について、得られた還元粘度を縦軸に、乾燥物換算の試料濃度を横軸にプロットして検量線を作成し、前記試料濃度を０に外挿することにより、試料の極限粘度を得る。試料がヒアルロン酸および／またはその塩である場合、下記式（３）に基づいて、試料の極限粘度から平均分子量Ｍを求めることができる。
式３
極限粘度（ｃｍ ３ ／ｇ）＝ｋ’Ｍα ・・・・・（３）
（上記式（３）において、ｋ’＝０．０３６，α＝０．７８である。）
Next, for each sample solution, the reduced viscosity obtained is plotted on the vertical axis and the sample concentration in terms of dry matter is plotted on the horizontal axis to create a calibration curve, and the sample concentration is extrapolated to 0, Get intrinsic viscosity. When the sample is hyaluronic acid and / or a salt thereof, the average molecular weight M can be determined from the intrinsic viscosity of the sample based on the following formula (3).
Formula 3
Intrinsic viscosity ( cm 3 / g) = k′M α (3)
(In the above formula (3), k ′ = 0.036 and α = 0.78.)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006125139A JP5066342B2 (en) | 2006-04-28 | 2006-04-28 | Novel hyaluronic acid and / or salt thereof, and cosmetics, pharmaceutical compositions, food compositions, and cosmetic kits using the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006125139A JP5066342B2 (en) | 2006-04-28 | 2006-04-28 | Novel hyaluronic acid and / or salt thereof, and cosmetics, pharmaceutical compositions, food compositions, and cosmetic kits using the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007297460A JP2007297460A (en) | 2007-11-15 |
| JP2007297460A5 true JP2007297460A5 (en) | 2009-09-17 |
| JP5066342B2 JP5066342B2 (en) | 2012-11-07 |
Family
ID=38767232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006125139A Active JP5066342B2 (en) | 2006-04-28 | 2006-04-28 | Novel hyaluronic acid and / or salt thereof, and cosmetics, pharmaceutical compositions, food compositions, and cosmetic kits using the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5066342B2 (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006352358B2 (en) * | 2006-12-26 | 2014-03-13 | Bomi Patel Framroze | Skin lightening composition for hyperpigmented skin |
| KR101449687B1 (en) * | 2008-03-13 | 2014-10-14 | 주식회사 바이오랜드 | Anti-aging Composition for external Use comprising low and high molecular weight hyaluronic acids and the polysaccharides extracted from roots of Ulmus davidiana var. japonica |
| JP5561636B2 (en) * | 2009-03-03 | 2014-07-30 | 東洋紡株式会社 | Improved method for producing hyaluronic acid |
| JP5089650B2 (en) * | 2009-05-20 | 2012-12-05 | キユーピー株式会社 | Acid gel food |
| JP5193131B2 (en) * | 2009-06-19 | 2013-05-08 | キユーピー株式会社 | Acid transparent gel food |
| JP5140636B2 (en) * | 2009-06-19 | 2013-02-06 | キユーピー株式会社 | Acid transparent gel food |
| TWI383796B (en) * | 2009-08-14 | 2013-02-01 | Holy Stone Healthcare Co Ltd | Use of hyaluronic acid mixture for the treatment and prevention of peptic ulcer and duodenal ulcer |
| JP2011057607A (en) * | 2009-09-09 | 2011-03-24 | Toshitsu Kagaku Kenkyusho:Kk | Composition containing hyaluronic acid and hyaluronic acid oligo-saccharide |
| JP5887072B2 (en) * | 2010-06-04 | 2016-03-16 | ロート製薬株式会社 | Hyaluronic acid-containing emulsion composition |
| JP5578955B2 (en) * | 2010-06-16 | 2014-08-27 | キユーピー株式会社 | Hyaluronic acid and glucosamine-containing tablets |
| JP2012153614A (en) * | 2011-01-24 | 2012-08-16 | Unitika Ltd | Collagen production promoter |
| JP5840107B2 (en) | 2012-06-17 | 2016-01-06 | コスメディ製薬株式会社 | Hyaluronic acid gel and method for producing the same |
| JP6348776B2 (en) * | 2013-06-04 | 2018-06-27 | キッコーマンバイオケミファ株式会社 | Skin quality improving oral composition, food and oral medicine |
| US9956190B2 (en) | 2014-04-15 | 2018-05-01 | Vizuri Health Sciences Llc | Topical compositions for pain relief, manufacture and use |
| CN105168238A (en) * | 2015-08-13 | 2015-12-23 | 南京天纵易康生物科技股份有限公司 | Hyaluronic temperature-sensitive gel and preparation method and application thereof |
| JP6743382B2 (en) * | 2015-12-18 | 2020-08-19 | 味の素株式会社 | External skin preparation |
| JP6974952B2 (en) * | 2016-04-28 | 2021-12-01 | ロート製薬株式会社 | External composition |
| GB201703674D0 (en) * | 2017-03-08 | 2017-04-19 | Givaudan Sa | Chemical composition |
| JP6912327B2 (en) * | 2017-09-04 | 2021-08-04 | 大日精化工業株式会社 | Manufacturing method of medical / beauty materials and medical / beauty materials |
| CN107950924B (en) * | 2017-11-27 | 2021-10-22 | 武汉梁子湖水产品加工有限公司 | Method for keeping taste of frozen Wuchang fish |
| KR102215559B1 (en) * | 2019-10-08 | 2021-02-15 | 주식회사 제네웰 | Preparing method of dry hyaluronic acid based composition and dry hyaluronic acid based composition |
| CN114848520B (en) * | 2022-06-20 | 2023-08-01 | 上海新高姿化妆品有限公司 | Whitening and repairing composition and application thereof |
| WO2024034159A1 (en) * | 2022-08-09 | 2024-02-15 | 株式会社 資生堂 | Cosmetic material and beauty care method |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57212108A (en) * | 1981-06-17 | 1982-12-27 | Balazs Endre A | Hyaluronate composition and cosmetic blend containing same |
| JPS62292710A (en) * | 1986-06-12 | 1987-12-19 | Lion Corp | Skin cosmetic |
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2006
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