JP2007001977A5 - - Google Patents
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- Publication number
- JP2007001977A5 JP2007001977A5 JP2006170554A JP2006170554A JP2007001977A5 JP 2007001977 A5 JP2007001977 A5 JP 2007001977A5 JP 2006170554 A JP2006170554 A JP 2006170554A JP 2006170554 A JP2006170554 A JP 2006170554A JP 2007001977 A5 JP2007001977 A5 JP 2007001977A5
- Authority
- JP
- Japan
- Prior art keywords
- treatment
- extract
- pharmaceutical composition
- cell line
- diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000284 extract Substances 0.000 claims 28
- 239000008194 pharmaceutical composition Substances 0.000 claims 20
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 238000000034 method Methods 0.000 claims 10
- 125000004432 carbon atom Chemical group C* 0.000 claims 9
- 201000010099 disease Diseases 0.000 claims 8
- 241000196324 Embryophyta Species 0.000 claims 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 4
- 230000006378 damage Effects 0.000 claims 4
- 238000001914 filtration Methods 0.000 claims 4
- 208000033808 peripheral neuropathy Diseases 0.000 claims 4
- 241001519274 Ajuga reptans Species 0.000 claims 3
- 239000002028 Biomass Substances 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 239000011347 resin Substances 0.000 claims 3
- 229920005989 resin Polymers 0.000 claims 3
- 208000024827 Alzheimer disease Diseases 0.000 claims 2
- 206010003645 Atopy Diseases 0.000 claims 2
- 206010012335 Dependence Diseases 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 102000011782 Keratins Human genes 0.000 claims 2
- 108010076876 Keratins Proteins 0.000 claims 2
- 201000004681 Psoriasis Diseases 0.000 claims 2
- 208000026062 Tissue disease Diseases 0.000 claims 2
- 239000008346 aqueous phase Substances 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 150000002016 disaccharides Chemical class 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 238000010438 heat treatment Methods 0.000 claims 2
- 230000002779 inactivation Effects 0.000 claims 2
- 239000002207 metabolite Substances 0.000 claims 2
- 150000002772 monosaccharides Chemical group 0.000 claims 2
- 210000000653 nervous system Anatomy 0.000 claims 2
- 201000001119 neuropathy Diseases 0.000 claims 2
- 230000007823 neuropathy Effects 0.000 claims 2
- 229930015704 phenylpropanoid Natural products 0.000 claims 2
- 150000002995 phenylpropanoid derivatives Chemical class 0.000 claims 2
- 229930010796 primary metabolite Natural products 0.000 claims 2
- 230000000241 respiratory effect Effects 0.000 claims 2
- 229930000044 secondary metabolite Natural products 0.000 claims 2
- 230000009759 skin aging Effects 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 208000020431 spinal cord injury Diseases 0.000 claims 2
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical group OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 claims 2
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 claims 1
- 208000002874 Acne Vulgaris Diseases 0.000 claims 1
- 208000007848 Alcoholism Diseases 0.000 claims 1
- 201000004384 Alopecia Diseases 0.000 claims 1
- 206010002383 Angina Pectoris Diseases 0.000 claims 1
- 206010059245 Angiopathy Diseases 0.000 claims 1
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 201000006474 Brain Ischemia Diseases 0.000 claims 1
- 208000002177 Cataract Diseases 0.000 claims 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 claims 1
- 206010008120 Cerebral ischaemia Diseases 0.000 claims 1
- 230000010736 Chelating Activity Effects 0.000 claims 1
- 208000032544 Cicatrix Diseases 0.000 claims 1
- 229920000742 Cotton Polymers 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 241000701022 Cytomegalovirus Species 0.000 claims 1
- 206010011831 Cytomegalovirus infection Diseases 0.000 claims 1
- 208000020401 Depressive disease Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 206010019233 Headaches Diseases 0.000 claims 1
- 208000032843 Hemorrhage Diseases 0.000 claims 1
- 208000009889 Herpes Simplex Diseases 0.000 claims 1
- 208000007514 Herpes zoster Diseases 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 206010021143 Hypoxia Diseases 0.000 claims 1
- 208000012659 Joint disease Diseases 0.000 claims 1
- 208000029549 Muscle injury Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010029098 Neoplasm skin Diseases 0.000 claims 1
- 239000004677 Nylon Substances 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 208000004210 Pressure Ulcer Diseases 0.000 claims 1
- 206010036790 Productive cough Diseases 0.000 claims 1
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 1
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 1
- 206010063837 Reperfusion injury Diseases 0.000 claims 1
- 201000007737 Retinal degeneration Diseases 0.000 claims 1
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 claims 1
- 241000700584 Simplexvirus Species 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 229910000831 Steel Inorganic materials 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000002847 Surgical Wound Diseases 0.000 claims 1
- 208000010641 Tooth disease Diseases 0.000 claims 1
- 208000025865 Ulcer Diseases 0.000 claims 1
- 208000036142 Viral infection Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 206010000496 acne Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- 201000007930 alcohol dependence Diseases 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 230000007815 allergy Effects 0.000 claims 1
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 230000001363 autoimmune Effects 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 230000003542 behavioural effect Effects 0.000 claims 1
- 238000004061 bleaching Methods 0.000 claims 1
- 230000000740 bleeding effect Effects 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 208000029028 brain injury Diseases 0.000 claims 1
- 229940074360 caffeic acid Drugs 0.000 claims 1
- 235000004883 caffeic acid Nutrition 0.000 claims 1
- 206010008118 cerebral infarction Diseases 0.000 claims 1
- 230000007882 cirrhosis Effects 0.000 claims 1
- 208000019425 cirrhosis of liver Diseases 0.000 claims 1
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 claims 1
- 239000000701 coagulant Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000007887 coronary angioplasty Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 238000010828 elution Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 229930182830 galactose Natural products 0.000 claims 1
- 210000001156 gastric mucosa Anatomy 0.000 claims 1
- 208000007565 gingivitis Diseases 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 230000005484 gravity Effects 0.000 claims 1
- 208000024963 hair loss Diseases 0.000 claims 1
- 230000003676 hair loss Effects 0.000 claims 1
- 231100000869 headache Toxicity 0.000 claims 1
- 208000019622 heart disease Diseases 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 210000004347 intestinal mucosa Anatomy 0.000 claims 1
- 230000000302 ischemic effect Effects 0.000 claims 1
- 230000000366 juvenile effect Effects 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 210000002200 mouth mucosa Anatomy 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 230000014508 negative regulation of coagulation Effects 0.000 claims 1
- 208000015122 neurodegenerative disease Diseases 0.000 claims 1
- 230000000926 neurological effect Effects 0.000 claims 1
- 229920001778 nylon Polymers 0.000 claims 1
- 208000028169 periodontal disease Diseases 0.000 claims 1
- 208000027232 peripheral nervous system disease Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000001782 photodegradation Methods 0.000 claims 1
- 238000006303 photolysis reaction Methods 0.000 claims 1
- 230000015843 photosynthesis, light reaction Effects 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 238000011085 pressure filtration Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 208000002815 pulmonary hypertension Diseases 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 230000004258 retinal degeneration Effects 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 206010039083 rhinitis Diseases 0.000 claims 1
- 231100000241 scar Toxicity 0.000 claims 1
- 230000037387 scars Effects 0.000 claims 1
- 201000000980 schizophrenia Diseases 0.000 claims 1
- 208000008742 seborrheic dermatitis Diseases 0.000 claims 1
- 230000001953 sensory effect Effects 0.000 claims 1
- 230000035939 shock Effects 0.000 claims 1
- 230000037380 skin damage Effects 0.000 claims 1
- 210000003802 sputum Anatomy 0.000 claims 1
- 208000024794 sputum Diseases 0.000 claims 1
- 239000010959 steel Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 230000000451 tissue damage Effects 0.000 claims 1
- 231100000827 tissue damage Toxicity 0.000 claims 1
- 230000008359 toxicosis Effects 0.000 claims 1
- 231100000397 ulcer Toxicity 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05425441 | 2005-06-20 | ||
| EP05425441.2 | 2005-06-20 | ||
| EP05425585.6A EP1736166B2 (en) | 2005-06-20 | 2005-08-08 | Extracts from Ajuga reptans cell lines, their preparation and use |
| EP05425585.6 | 2005-08-08 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013173952A Division JP5788936B2 (ja) | 2005-06-20 | 2013-08-23 | アジュガ・レプタンス細胞株由来の抽出物、その製造及び使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007001977A JP2007001977A (ja) | 2007-01-11 |
| JP2007001977A5 true JP2007001977A5 (enExample) | 2009-08-06 |
| JP5443664B2 JP5443664B2 (ja) | 2014-03-19 |
Family
ID=37025252
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006170554A Active JP5443664B2 (ja) | 2005-06-20 | 2006-06-20 | アジュガ・レプタンス細胞株由来の抽出物、その製造及び使用 |
| JP2013173952A Active JP5788936B2 (ja) | 2005-06-20 | 2013-08-23 | アジュガ・レプタンス細胞株由来の抽出物、その製造及び使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013173952A Active JP5788936B2 (ja) | 2005-06-20 | 2013-08-23 | アジュガ・レプタンス細胞株由来の抽出物、その製造及び使用 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US9623063B2 (enExample) |
| EP (2) | EP1736166B2 (enExample) |
| JP (2) | JP5443664B2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101526303B1 (ko) * | 2008-03-31 | 2015-06-05 | (주)아모레퍼시픽 | 항노화용 화장료 조성물 |
| EP2319914A1 (en) * | 2009-11-09 | 2011-05-11 | I.R.B. Istituto Di Ricerche Biotecnologiche S.r.l. | Preparation and use of plant meristem cells with a high content of caffeic acid derivatives |
| EP2340808A1 (en) | 2009-12-21 | 2011-07-06 | I.R.B. Istituto Di Ricerche Biotecnologiche S.r.l. | Synergic combination of phenylpropanoids, such as verbascoside or teupolioside, and mesalamine |
| IT1400234B1 (it) * | 2010-05-07 | 2013-05-24 | I R B Istituto Di Ricerche Biotecnologiche S R L | Derivati esterei di fenilpropanoidi |
| WO2013156858A1 (en) * | 2012-04-20 | 2013-10-24 | Purapharm Company Limited | Materials and methods for prevention and treatment of viral infections |
| US9289374B2 (en) * | 2014-04-23 | 2016-03-22 | Lifevantage Corporation | Topical compositions and methods for reducing oxidative stress |
| ITUB20159551A1 (it) * | 2015-12-21 | 2017-06-21 | Purytra Farm S P A | Composizione farmaceutica per il trattamento dell?iperplasia prostatica |
| EP3624763A1 (en) * | 2017-05-18 | 2020-03-25 | Medena AG | Use of naturally glycosylated polyphenols as protective agents against the effects of ultraviolet irradiation |
| CN110117301B (zh) * | 2018-02-06 | 2021-05-04 | 上海东西智荟生物医药有限公司 | 用于防治神经退行性疾病的新化合物及其应用 |
| CN108776121B (zh) * | 2018-04-08 | 2021-07-30 | 广州卡马生物科技有限公司 | 一种基于荧光猝灭原理对药材中抗氧剂的高通量筛选方法 |
| WO2020008117A1 (fr) * | 2018-07-06 | 2020-01-09 | Laboratoires De Biologie Vegetale Yves Rocher | Utilisation cosmetique de hrgp (hydroxyprolin rich glycoproteins) issues de cellules d'ajuga reptans pour prevenir et/ou lutter contre les effets du vieillissement de la peau |
| CN115466248B (zh) * | 2022-02-08 | 2024-10-29 | 厦门稀土材料研究所 | 二萜类化合物及其提取方法和用途 |
| CN115840019B (zh) * | 2022-12-27 | 2025-01-07 | 贵州百灵企业集团制药股份有限公司 | 一种艾纳香药材质量检测方法 |
| IT202300017805A1 (it) * | 2023-08-30 | 2025-03-02 | Idi Integratori Dietetici Italiani S R L | Nuova composizione comprendente teupolioside e inositolo |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3926390A1 (de) * | 1989-08-10 | 1991-02-14 | Bayer Ag | Verwendung von lysozym genen in pflanzen zur resistenzerhoehung |
| JPH07223962A (ja) * | 1994-02-14 | 1995-08-22 | Pola Chem Ind Inc | 血栓抑制剤及びそれを含む組成物 |
| CN1244317C (zh) * | 1996-08-02 | 2006-03-08 | 株式会社资生堂 | 用于提高透明质酸产率的组合物及其制备方法 |
| IT1317732B1 (it) * | 2000-01-20 | 2003-07-15 | Giuliani Spa | Composti ad attivita' antiossidante, composizioni utili qualiintegratori alimentari che li contengono e procedimento per |
| JP3448006B2 (ja) * | 2000-03-29 | 2003-09-16 | 独立行政法人食品総合研究所 | 機能性エマルション |
| JP3430132B2 (ja) * | 2000-08-22 | 2003-07-28 | 株式会社東洋新薬 | イネ若葉中のγ−アミノ酪酸含量を高める方法 |
| WO2004033673A2 (en) † | 2002-10-10 | 2004-04-22 | I.R.B. Istituto Di Ricerche Biotecnologiche S.R.L. | Production process for plant biomass and its use |
| MXPA06009979A (es) * | 2004-03-02 | 2007-03-01 | Giuliani Spa | Composicion para regular el trofismo de foliculos pilosos y la produccion cutanea de sebo y el uso del mismo en alopecia androgenica. |
| ITMI20050498A1 (it) | 2005-03-24 | 2006-09-25 | Giuliani Spa | Composizione a base di estratti vegetali di ajuga reptans per prevenire la caduta dei capelli stimolare la crescita dei capelli regolare la produzione di sebo |
-
2005
- 2005-08-08 EP EP05425585.6A patent/EP1736166B2/en not_active Expired - Lifetime
- 2005-08-08 EP EP08162332.4A patent/EP1997501B1/en not_active Expired - Lifetime
-
2006
- 2006-06-19 US US11/455,505 patent/US9623063B2/en active Active
- 2006-06-20 JP JP2006170554A patent/JP5443664B2/ja active Active
-
2013
- 2013-08-23 JP JP2013173952A patent/JP5788936B2/ja active Active
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