JP2006527380A5 - - Google Patents
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- Publication number
- JP2006527380A5 JP2006527380A5 JP2006516796A JP2006516796A JP2006527380A5 JP 2006527380 A5 JP2006527380 A5 JP 2006527380A5 JP 2006516796 A JP2006516796 A JP 2006516796A JP 2006516796 A JP2006516796 A JP 2006516796A JP 2006527380 A5 JP2006527380 A5 JP 2006527380A5
- Authority
- JP
- Japan
- Prior art keywords
- electrode
- surface substrate
- cell
- substrate according
- gate electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000758 substrate Substances 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 7
- 230000001737 promoting effect Effects 0.000 claims 4
- 102400001107 Secretory component Human genes 0.000 claims 2
- 210000000170 cell membrane Anatomy 0.000 claims 2
- 229910021420 polycrystalline silicon Inorganic materials 0.000 claims 2
- 229920005591 polysilicon Polymers 0.000 claims 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 230000021164 cell adhesion Effects 0.000 claims 1
- 230000023402 cell communication Effects 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 210000000078 claw Anatomy 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 238000005530 etching Methods 0.000 claims 1
- 210000002744 extracellular matrix Anatomy 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 238000001459 lithography Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47703703P | 2003-06-10 | 2003-06-10 | |
| US60/477,037 | 2003-06-10 | ||
| PCT/IL2004/000502 WO2004109282A1 (en) | 2003-06-10 | 2004-06-10 | Electronic device for communication with living cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006527380A JP2006527380A (ja) | 2006-11-30 |
| JP2006527380A5 true JP2006527380A5 (https=) | 2007-05-10 |
| JP4728956B2 JP4728956B2 (ja) | 2011-07-20 |
Family
ID=33511831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006516796A Expired - Lifetime JP4728956B2 (ja) | 2003-06-10 | 2004-06-10 | 生体細胞との通信のための電子装置 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US7795039B2 (https=) |
| EP (1) | EP1634075B1 (https=) |
| JP (1) | JP4728956B2 (https=) |
| WO (1) | WO2004109282A1 (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1634075B1 (en) | 2003-06-10 | 2015-01-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Electronic device for communication with living cells |
| GB0322010D0 (en) * | 2003-09-19 | 2003-10-22 | Univ Cambridge Tech | Detection of molecular interactions using field effect transistors |
| CA2643997A1 (en) * | 2006-03-15 | 2008-03-06 | President And Fellows Of Harvard College | Nanobioelectronics |
| US9102521B2 (en) | 2006-06-12 | 2015-08-11 | President And Fellows Of Harvard College | Nanosensors and related technologies |
| WO2008021758A1 (en) * | 2006-08-11 | 2008-02-21 | Home Diagnostics, Inc. | Methods for fabricating a biosensor with a surface texture |
| WO2008127314A1 (en) | 2006-11-22 | 2008-10-23 | President And Fellows Of Harvard College | High-sensitivity nanoscale wire sensors |
| US7948015B2 (en) | 2006-12-14 | 2011-05-24 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US11339430B2 (en) | 2007-07-10 | 2022-05-24 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US8349167B2 (en) | 2006-12-14 | 2013-01-08 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| WO2008111047A1 (en) * | 2007-03-09 | 2008-09-18 | Imec Vzw | Micro-nails for use in electrical interaction with cells |
| US10202711B2 (en) * | 2007-05-09 | 2019-02-12 | Massachusetts Institute Of Technology | Tunable surface |
| JP5712129B2 (ja) * | 2008-09-02 | 2015-05-07 | ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント | ナノ構造化微小電極およびそれを組み込んだバイオセンシング装置 |
| US20100137143A1 (en) | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| US20100301398A1 (en) | 2009-05-29 | 2010-12-02 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| WO2010121130A2 (en) | 2009-04-16 | 2010-10-21 | President And Fellows Of Harvard College | Molecular delivery with nanowires |
| US20120261274A1 (en) | 2009-05-29 | 2012-10-18 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
| US8776573B2 (en) | 2009-05-29 | 2014-07-15 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
| US9297796B2 (en) | 2009-09-24 | 2016-03-29 | President And Fellows Of Harvard College | Bent nanowires and related probing of species |
| US8487790B2 (en) | 2010-06-30 | 2013-07-16 | Life Technologies Corporation | Chemical detection circuit including a serializer circuit |
| EP2588850B1 (en) | 2010-06-30 | 2016-12-28 | Life Technologies Corporation | Method for dry testing isfet arrays |
| AU2011226767B1 (en) | 2010-06-30 | 2011-11-10 | Life Technologies Corporation | Ion-sensing charge-accumulation circuits and methods |
| US11307166B2 (en) | 2010-07-01 | 2022-04-19 | Life Technologies Corporation | Column ADC |
| CN103168341B (zh) | 2010-07-03 | 2016-10-05 | 生命科技公司 | 具有轻度掺杂的排出装置的化学敏感的传感器 |
| EP2617061B1 (en) | 2010-09-15 | 2021-06-30 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
| JP5913323B2 (ja) | 2010-09-24 | 2016-04-27 | ライフ テクノロジーズ コーポレーション | マッチドペアトランジスタ回路 |
| US9629995B2 (en) | 2011-05-26 | 2017-04-25 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Biomolecular electronic device and process of use |
| US9595685B2 (en) | 2011-06-10 | 2017-03-14 | President And Fellows Of Harvard College | Nanoscale wires, nanoscale wire FET devices, and nanotube-electronic hybrid devices for sensing and other applications |
| US9762233B2 (en) * | 2011-08-16 | 2017-09-12 | Erez Halahmi | System for a contactless control of a field effect transistor |
| KR101366391B1 (ko) * | 2011-10-05 | 2014-02-25 | 한양대학교 산학협력단 | 세포 계수용 칩 |
| US9970984B2 (en) | 2011-12-01 | 2018-05-15 | Life Technologies Corporation | Method and apparatus for identifying defects in a chemical sensor array |
| US8786331B2 (en) | 2012-05-29 | 2014-07-22 | Life Technologies Corporation | System for reducing noise in a chemical sensor array |
| US9080968B2 (en) | 2013-01-04 | 2015-07-14 | Life Technologies Corporation | Methods and systems for point of use removal of sacrificial material |
| US9841398B2 (en) | 2013-01-08 | 2017-12-12 | Life Technologies Corporation | Methods for manufacturing well structures for low-noise chemical sensors |
| US8963216B2 (en) | 2013-03-13 | 2015-02-24 | Life Technologies Corporation | Chemical sensor with sidewall spacer sensor surface |
| US9835585B2 (en) | 2013-03-15 | 2017-12-05 | Life Technologies Corporation | Chemical sensor with protruded sensor surface |
| CN105264366B (zh) | 2013-03-15 | 2019-04-16 | 生命科技公司 | 具有一致传感器表面区域的化学传感器 |
| US20140264471A1 (en) * | 2013-03-15 | 2014-09-18 | Life Technologies Corporation | Chemical device with thin conductive element |
| US20140336063A1 (en) | 2013-05-09 | 2014-11-13 | Life Technologies Corporation | Windowed Sequencing |
| US10458942B2 (en) | 2013-06-10 | 2019-10-29 | Life Technologies Corporation | Chemical sensor array having multiple sensors per well |
| TWI647842B (zh) * | 2013-08-22 | 2019-01-11 | 美商生命技術公司 | 具薄導電元件之化學裝置 |
| US10077472B2 (en) | 2014-12-18 | 2018-09-18 | Life Technologies Corporation | High data rate integrated circuit with power management |
| CN111505087A (zh) | 2014-12-18 | 2020-08-07 | 生命科技公司 | 使用大规模 fet 阵列测量分析物的方法和装置 |
| EP3234576B1 (en) | 2014-12-18 | 2023-11-22 | Life Technologies Corporation | High data rate integrated circuit with transmitter configuration |
| US20180169403A1 (en) | 2015-01-09 | 2018-06-21 | President And Fellows Of Harvard College | Nanowire arrays for neurotechnology and other applications |
| GB201512600D0 (en) * | 2015-07-17 | 2015-08-26 | Koniku Ltd | Cell culture, transport and investigation |
| US11474103B2 (en) | 2017-02-17 | 2022-10-18 | Koniku Inc. | Systems for detection |
| CN107085097B (zh) * | 2017-05-14 | 2020-08-28 | 浙江达普生物科技有限公司 | 一种血检芯片及其制作方法 |
| KR20250125660A (ko) * | 2024-02-15 | 2025-08-22 | 서울대학교산학협력단 | 수직 나노구조체가 적용된 전계 효과 트랜지스터를 포함하는 세포 신호 측정 소자와 그 제조 및 동작 방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4546083A (en) * | 1983-04-22 | 1985-10-08 | Stolle Research & Development Corporation | Method and device for cell culture growth |
| US6846654B1 (en) * | 1983-11-29 | 2005-01-25 | Igen International, Inc. | Catalytic antibodies as chemical sensors |
| CA2157388C (en) * | 1993-03-01 | 1998-12-15 | Daniel P. Witt | Analogs for specific oligosaccharide-protein interactions and uses thereof |
| DE19841337C1 (de) | 1998-05-27 | 1999-09-23 | Micronas Intermetall Gmbh | Verfahren und Vorrichtung zur intrazellulären Manipulation einer biologischen Zelle |
| JP3515908B2 (ja) | 1998-09-24 | 2004-04-05 | エヌ・ティ・ティ・アドバンステクノロジ株式会社 | 微少量オンラインバイオセンサー及びその製造方法 |
| IL145020A0 (en) * | 1999-02-22 | 2002-06-30 | Yissum Res Dev Co | A hybrid electrical device with biological components |
| JP2001156398A (ja) | 1999-05-19 | 2001-06-08 | Canon Inc | 半導体素子の製造方法、半導体素子、及びジャイロ |
| NZ518057A (en) | 1999-10-01 | 2004-01-30 | Sophion Bioscience As | A substrate and a method for determining and/or monitoring electrophysiological properties of ion channels |
| JP2004514417A (ja) * | 2000-07-07 | 2004-05-20 | ブリストル−マイヤーズ スクイブ カンパニー | 薬品発見用化合物の高速処理スクリーニングに適した電気生理学的配置 |
| US6465331B1 (en) * | 2000-08-31 | 2002-10-15 | Micron Technology, Inc. | DRAM fabricated on a silicon-on-insulator (SOI) substrate having bi-level digit lines |
| AU2003240561A1 (en) | 2002-06-06 | 2003-12-22 | Rutgers, The State University Of New Jersey | MULTIFUNCTIONAL BIOSENSOR BASED ON ZnO NANOSTRUCTURES |
| IL152746A0 (en) | 2002-11-11 | 2003-06-24 | Yissum Res Dev Co | Biosensor for molecules |
| EP1634075B1 (en) | 2003-06-10 | 2015-01-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Electronic device for communication with living cells |
| US7270973B2 (en) * | 2003-12-23 | 2007-09-18 | The United States Of America As Represented By The Secretary Of The Navy | Catalytic enzyme-modified textiles for active protection from toxins |
-
2004
- 2004-06-10 EP EP04736573.9A patent/EP1634075B1/en not_active Expired - Lifetime
- 2004-06-10 WO PCT/IL2004/000502 patent/WO2004109282A1/en not_active Ceased
- 2004-06-10 US US10/560,315 patent/US7795039B2/en not_active Expired - Fee Related
- 2004-06-10 JP JP2006516796A patent/JP4728956B2/ja not_active Expired - Lifetime
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