JP2006526412A5 - - Google Patents

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Publication number
JP2006526412A5
JP2006526412A5 JP2006515008A JP2006515008A JP2006526412A5 JP 2006526412 A5 JP2006526412 A5 JP 2006526412A5 JP 2006515008 A JP2006515008 A JP 2006515008A JP 2006515008 A JP2006515008 A JP 2006515008A JP 2006526412 A5 JP2006526412 A5 JP 2006526412A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006515008A
Other languages
Japanese (ja)
Other versions
JP2006526412A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/016920 external-priority patent/WO2004108954A1/en
Publication of JP2006526412A publication Critical patent/JP2006526412A/ja
Publication of JP2006526412A5 publication Critical patent/JP2006526412A5/ja
Pending legal-status Critical Current

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JP2006515008A 2003-05-30 2004-05-28 イリノテカン毒性を推定する方法および組成物 Pending JP2006526412A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47482603P 2003-05-30 2003-05-30
PCT/US2004/016920 WO2004108954A1 (en) 2003-05-30 2004-05-28 Methods and compositions for predicting irinotecan toxicity

Publications (2)

Publication Number Publication Date
JP2006526412A JP2006526412A (ja) 2006-11-24
JP2006526412A5 true JP2006526412A5 (enExample) 2007-02-08

Family

ID=33511633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006515008A Pending JP2006526412A (ja) 2003-05-30 2004-05-28 イリノテカン毒性を推定する方法および組成物

Country Status (8)

Country Link
US (1) US7807350B2 (enExample)
EP (1) EP1629111B1 (enExample)
JP (1) JP2006526412A (enExample)
AT (1) ATE397091T1 (enExample)
CA (1) CA2527320A1 (enExample)
DE (1) DE602004014135D1 (enExample)
ES (1) ES2308208T3 (enExample)
WO (1) WO2004108954A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007055261A1 (ja) * 2005-11-10 2007-05-18 The New Industry Research Organization Ugt1a1遺伝子多型の検査法
KR101153058B1 (ko) 2006-11-30 2012-06-04 아크레이 가부시키가이샤 Ugt1a1 유전자 증폭용 프라이머 셋트, 그것을 포함하는 ugt1a1 유전자 증폭용 시약 및 그 용도
CN107858429A (zh) * 2017-11-10 2018-03-30 广州金域医学检验集团股份有限公司 用于检测ugt1a1基因启动子区ta重复多态性的扩增引物、方法及应用

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
WO1994022846A1 (en) 1993-03-30 1994-10-13 Pfizer Inc. Compounds enhancing antitumor activity of other cytotoxic agents
EP0721328A4 (en) 1993-09-27 1997-09-17 Smithkline Beecham Corp CAMPTOTHECIN FORMULATIONS
US5786344A (en) 1994-07-05 1998-07-28 Arch Development Corporation Camptothecin drug combinations and methods with reduced side effects
US5919816A (en) * 1994-11-14 1999-07-06 Bionumerik Pharmaceuticals, Inc. Formulations and methods of reducing toxicity of antineoplastic agents
US5972614A (en) * 1995-12-06 1999-10-26 Genaissance Pharmaceuticals Genome anthologies for harvesting gene variants
DE69734237T2 (de) 1996-03-01 2006-07-06 The University Court Of The University Of Dundee, Dundee Versuchsystem für einen Arzneimittelversuch
US6287834B1 (en) * 1996-05-17 2001-09-11 Endorecherche, Inc. Characterization and use of an isolated uridine diphospho-glucuronosyltransferase
DE19744676A1 (de) 1997-10-10 1999-04-15 Forschungszentrum Borstel Zent Kombinationspräparate für die Therapie von Tumoren
WO1999057322A2 (en) 1998-05-07 1999-11-11 Axys Pharmaceuticals, Inc. Genotyping the human udp-glucuronosyltransferase 1 (ugt1) gene
US6448003B1 (en) * 1998-06-10 2002-09-10 Dna Sciences Laboratories, Inc. Genotyping the human phenol sulfotransferbase 2 gene STP2
US6407117B1 (en) * 1998-06-18 2002-06-18 The George Washington University Method of administering camptothecin compounds for the treatment of cancer with reduced side effects
US6319678B1 (en) * 1998-06-26 2001-11-20 Panvera Corporation Process for glucuronidation screening
US6586175B1 (en) * 1998-07-28 2003-07-01 Dna Sciences Laboratories, Inc. Genotyping the human UDP-glucuronosyltransferase 2B7 (UGT2B7) gene
US6395481B1 (en) * 1999-02-16 2002-05-28 Arch Development Corp. Methods for detection of promoter polymorphism in a UGT gene promoter
AU2001255397A1 (en) 2000-04-18 2001-10-30 Genaissance Pharmaceuticals, Inc. Haplotypes of the ugt1a1 gene
EP1325152A2 (en) 2000-07-14 2003-07-09 F. Hoffmann-La Roche Ag Method for detecting pre-disposition to hepatotoxicity
AU2002245039A1 (en) 2000-11-28 2002-07-30 Dna Sciences Laboratories, Inc. Genetic typing of human genes and related materials and methods
EP1352970B1 (en) 2000-12-12 2010-06-02 Nagoya Industrial Science Research Institute Method of estimating the risk of expression of adverse drug reaction caused by the administration of a compound, which is either metabloized per se by ugt1a1 or whose intermediate is metabolized by the enzyme
DE10100238A1 (de) * 2001-01-05 2002-08-22 Hannover Med Hochschule Verfahren zur Vorhersage des Gefährdungspotentials für Karzinomerkrankungen und entzündliche Darmerkrankungen und zugehörige Tests
WO2002059375A2 (en) * 2001-01-26 2002-08-01 University Of Chicago Determination of ugt2b7 gene polymorphisms for predicting ugt2b7 substrate toxicity and for optimising drug dosage
WO2003013534A2 (en) 2001-07-23 2003-02-20 Epidauros Biotechnologie Ag Methods for the treatment of cancer with irinotecan based on cyp3a5
JP4096037B2 (ja) 2002-08-12 2008-06-04 国立大学法人滋賀医科大学 グルクロン酸転移酵素遺伝子の変異解析による薬剤代謝活性の予測方法
US20040203034A1 (en) * 2003-01-03 2004-10-14 The University Of Chicago Optimization of cancer treatment with irinotecan

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