JP2006525994A - 非膵島組織における調節された膵ホルモンの産生を誘導する方法 - Google Patents

非膵島組織における調節された膵ホルモンの産生を誘導する方法 Download PDF

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JP2006525994A
JP2006525994A JP2006506631A JP2006506631A JP2006525994A JP 2006525994 A JP2006525994 A JP 2006525994A JP 2006506631 A JP2006506631 A JP 2006506631A JP 2006506631 A JP2006506631 A JP 2006506631A JP 2006525994 A JP2006525994 A JP 2006525994A
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サラ ファーバー，
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • C—CHEMISTRY; METALLURGY
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
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  • Physics & Mathematics (AREA)
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  • Microbiology (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006506631A 2003-05-12 2004-05-12 非膵島組織における調節された膵ホルモンの産生を誘導する方法 Pending JP2006525994A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46971503P 2003-05-12 2003-05-12
PCT/IB2004/001973 WO2004098646A1 (en) 2003-05-12 2004-05-12 Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues

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JP2010261850A Division JP2011068660A (ja) 2003-05-12 2010-11-24 非膵島組織における調節された膵ホルモンの産生を誘導する方法

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JP2006525994A true JP2006525994A (ja) 2006-11-16

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JP2006506631A Pending JP2006525994A (ja) 2003-05-12 2004-05-12 非膵島組織における調節された膵ホルモンの産生を誘導する方法
JP2010261850A Pending JP2011068660A (ja) 2003-05-12 2010-11-24 非膵島組織における調節された膵ホルモンの産生を誘導する方法

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EP (1) EP1624898A1 (enExample)
JP (2) JP2006525994A (enExample)
AU (1) AU2004236573B2 (enExample)
WO (1) WO2004098646A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019530439A (ja) * 2016-08-29 2019-10-24 ハッケンサック ユニヴァーシティ メディカル センター ヒトにおける血小板様細胞を含有する血液の血小板に富む画分の幹細胞性により成体細胞を再プログラミングするための組成物および方法

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774120B1 (en) 1999-06-01 2004-08-10 Sarah Ferber Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
US8778899B2 (en) 1999-06-01 2014-07-15 Sarah Ferber Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
CA2634510C (en) 2005-12-21 2018-01-09 Universite Catholique De Louvain Isolated liver stem cells
CN101573445A (zh) * 2006-09-22 2009-11-04 贝勒研究院 由胰腺腺泡细胞向胰岛素生成细胞的体内转化
CA2904198A1 (en) * 2013-03-15 2014-09-18 Universite De Geneve Use of insulin signaling antagonists, optionally in combination of transfection of non-beta cells, for inducing insulin production
KR102181336B1 (ko) 2013-06-13 2020-11-24 오르제네시스 엘티디. 세포 집단, 이의 전환분화 방법 및 이용 방법
JP6474394B2 (ja) 2013-07-05 2019-02-27 ユニベルシテ カトリック ドゥ ルーベン ヒト成体肝臓幹細胞由来の馴化培地および肝臓障害の治療におけるその使用
MA41296A (fr) * 2014-12-30 2017-11-07 Orgenesis Ltd Procédés de transdifférenciation et procédés d'utilisation de ceux-ci
US9957287B2 (en) 2016-05-26 2018-05-01 Cornell University Methods and compositions to treat type-1 and type-2 diabetes
WO2018044795A1 (en) 2016-08-29 2018-03-08 Yong Zhao Compositions and methods for programming adult cells with platelet rich fraction of blood containing platelet-like cells
WO2018207179A1 (en) 2017-05-08 2018-11-15 Orgenesis Ltd. Transdifferentiated cell populations and methods of use thereof
US11788062B2 (en) * 2017-07-27 2023-10-17 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Functional feline pancreatic cells from adipose tissue
CN112899351B (zh) * 2021-02-03 2022-08-26 东华大学 一种双重荧光定量pcr检测pdx模型小鼠细胞浸润状态试剂盒

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003500457A (ja) * 1999-06-01 2003-01-07 サラ ファーバー， 非ランゲルハンス島組織における調節された膵臓ホルモンを誘導する方法
WO2003033697A1 (en) * 2001-10-18 2003-04-24 Ixion Biotechnology, Inc. Conversion of liver stem and progenitor cells to pancreatic functional cells
JP2003304878A (ja) * 2002-04-17 2003-10-28 Susumu Kiyono インスリン産生細胞の誘導

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0206357D0 (en) * 2002-03-18 2002-05-01 Univ Bath Cells

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003500457A (ja) * 1999-06-01 2003-01-07 サラ ファーバー， 非ランゲルハンス島組織における調節された膵臓ホルモンを誘導する方法
WO2003033697A1 (en) * 2001-10-18 2003-04-24 Ixion Biotechnology, Inc. Conversion of liver stem and progenitor cells to pancreatic functional cells
JP2003304878A (ja) * 2002-04-17 2003-10-28 Susumu Kiyono インスリン産生細胞の誘導

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6010028021, ＫＯＪＩＭＡ，Ｈ． ｅｔ ａｌ, "Ｃｏｍｂｉｎｅｄ ｅｘｐｒｅｓｓｉｏｎ ｏｆ ｐａｎｃｒｅａｔｉｃ ｄｕｏｄｅｎａｌ ｈｏｍｅｏｂｏｘ １ ａｎｄ ｉｓｌｅｔ ｆａｃｔｏｒ １ ｉｎｄｕｃｅｓ ｉｍｍａｔｕｒｅ ｅｎｔｅｒｏｃｙｔｅ", Ｄｉａｂｅｔｅｓ, 2002, Ｖｏｌ．５１， Ｎｏ．５, ｐ．１３９８−４０８ *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019530439A (ja) * 2016-08-29 2019-10-24 ハッケンサック ユニヴァーシティ メディカル センター ヒトにおける血小板様細胞を含有する血液の血小板に富む画分の幹細胞性により成体細胞を再プログラミングするための組成物および方法
JP7219211B2 (ja) 2016-08-29 2023-02-07 ハッケンサック ユニヴァーシティ メディカル センター ヒトにおける血小板様細胞を含有する血液の血小板に富む画分の幹細胞性により成体細胞を再プログラミングするための組成物および方法

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WO2004098646A1 (en) 2004-11-18
AU2004236573B2 (en) 2009-10-22
EP1624898A1 (en) 2006-02-15
AU2004236573A1 (en) 2004-11-18
JP2011068660A (ja) 2011-04-07
WO2004098646B1 (en) 2005-04-28

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