JP2006525333A - 高親水性で正電荷に帯電した薬剤を取り込んだ生分解性ナノ粒子 - Google Patents

高親水性で正電荷に帯電した薬剤を取り込んだ生分解性ナノ粒子 Download PDF

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JP2006525333A
JP2006525333A JP2006513310A JP2006513310A JP2006525333A JP 2006525333 A JP2006525333 A JP 2006525333A JP 2006513310 A JP2006513310 A JP 2006513310A JP 2006513310 A JP2006513310 A JP 2006513310A JP 2006525333 A JP2006525333 A JP 2006525333A
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polymer
composition
treatment
polysaccharide
aminoglycoside
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Japanese (ja)
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JP2006525333A5 (https=
Inventor
カルメン ポペスク，
ハヤト オニウクセル，
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ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ
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Publication of JP2006525333A publication Critical patent/JP2006525333A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006513310A 2003-05-02 2004-04-26 高親水性で正電荷に帯電した薬剤を取り込んだ生分解性ナノ粒子 Withdrawn JP2006525333A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46740003P 2003-05-02 2003-05-02
PCT/US2004/012755 WO2004098564A2 (en) 2003-05-02 2004-04-26 Biodegradable nanoparticles comprising an aminoglycoside and a polymer like a polysaccharide

Publications (2)

Publication Number Publication Date
JP2006525333A true JP2006525333A (ja) 2006-11-09
JP2006525333A5 JP2006525333A5 (https=) 2007-06-21

Family

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JP2006513310A Withdrawn JP2006525333A (ja) 2003-05-02 2004-04-26 高親水性で正電荷に帯電した薬剤を取り込んだ生分解性ナノ粒子

Country Status (5)

Country Link
US (2) US20040247683A1 (https=)
EP (1) EP1620078A2 (https=)
JP (1) JP2006525333A (https=)
CA (1) CA2524368A1 (https=)
WO (1) WO2004098564A2 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2226567B1 (es) * 2003-06-20 2006-07-01 Universidad De Santiago De Compostela Nanoparticulas de acido hialuronico.
WO2005027873A2 (en) * 2003-06-20 2005-03-31 Alnis Biosciences, Inc. Therapeutic aminoglycoside-containing hydrogel nanoparticles
US8628690B2 (en) * 2004-02-23 2014-01-14 The Texas A&M University System Nanoemulsion compositions and methods of use thereof
US7780873B2 (en) * 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
US9119782B2 (en) 2006-03-20 2015-09-01 Mary P. McCourt Drug delivery means
US20090061006A1 (en) * 2006-03-31 2009-03-05 Carola Leuschner Layered Nanoparticles for Sustained Release of Small Molecules
US20110135742A1 (en) * 2006-06-20 2011-06-09 The Regents Of The University Of California Controlled release encapsulated anti-bacterial and anti-inflammatory nanoparticles
US20080102127A1 (en) * 2006-10-26 2008-05-01 Gao Hai Y Hybrid lipid-polymer nanoparticulate delivery composition
CA2729582C (en) 2008-07-01 2017-09-19 University Of Chicago Particles containing an opioid receptor antagonist and methods of use
CN103221070B (zh) 2010-08-30 2019-07-12 哈佛大学校长及研究员协会 用于狭窄病变和溶解血栓疗法的切变控制释放
US20180028684A1 (en) 2010-11-01 2018-02-01 Nanoderm Sciences, Inc. Targeted nanoparticles
US9161962B2 (en) 2010-11-01 2015-10-20 Nanoderm Sciences, Inc. Targeted therapeutic nanoparticles
WO2012059936A1 (en) 2010-11-03 2012-05-10 Padma Venkitachalam Devarajan Pharmaceutical compositions for colloidal drug delivery
US10285943B2 (en) 2010-12-02 2019-05-14 Greenmark Biomedical Inc. Aptamer bioconjugate drug delivery device
MX384232B (es) 2013-03-14 2025-03-14 Jerome J Schentag Vesiculas colestosomicas para incorporacion de moleculas en quilomicrones.
JP6564369B2 (ja) 2013-12-09 2019-08-21 デュレクト コーポレイション 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法
CA3004363A1 (en) 2015-11-06 2017-05-11 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Composition comprising a biocompatible and biodegradable polymer, nanocarries and a drug and methods of making and using the same
CN105664259B (zh) * 2016-01-18 2018-09-14 铜仁学院 医用钛合金植入物表面药物缓释系统的构建方法
CN106596922B (zh) * 2016-12-06 2018-06-15 湖南大学 用于检测卡那霉素的检测试剂及其制备方法和应用
CA3090303A1 (en) 2018-03-28 2019-10-03 Greenmark Biomedical Inc. Phosphate crosslinked starch nanoparticle and dental treatments
US20230355540A1 (en) 2020-09-29 2023-11-09 Oxford University Innovation Limited Stroke treatment
CN113069554B (zh) * 2021-04-13 2022-10-21 河南中医药大学 一种齐墩果酸季铵盐-肝素-壳聚糖纳米粒的制备方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2594374A (en) * 1949-10-11 1952-04-29 Usa Streptomycin-polymyxin-bacitracin composition
FR2631826B1 (fr) * 1988-05-27 1992-06-19 Centre Nat Rech Scient Vecteur particulaire utile notamment pour le transport de molecules a activite biologique et procede pour sa preparation
CA2084194C (en) * 1991-04-02 2003-05-20 Gregory John Russell-Jones Oral delivery systems for microparticles

Also Published As

Publication number Publication date
CA2524368A1 (en) 2004-11-18
WO2004098564A3 (en) 2005-02-10
US20040247683A1 (en) 2004-12-09
US20080241257A1 (en) 2008-10-02
EP1620078A2 (en) 2006-02-01
WO2004098564A2 (en) 2004-11-18

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