JP2006523121A - 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 - Google Patents
閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 Download PDFInfo
- Publication number
- JP2006523121A JP2006523121A JP2006507427A JP2006507427A JP2006523121A JP 2006523121 A JP2006523121 A JP 2006523121A JP 2006507427 A JP2006507427 A JP 2006507427A JP 2006507427 A JP2006507427 A JP 2006507427A JP 2006523121 A JP2006523121 A JP 2006523121A
- Authority
- JP
- Japan
- Prior art keywords
- implant
- magnetic
- magnet
- tissue
- pharyngeal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 73
- 230000029058 respiratory gaseous exchange Effects 0.000 title claims abstract description 23
- 208000001797 obstructive sleep apnea Diseases 0.000 title description 16
- 210000000746 body region Anatomy 0.000 title description 5
- 239000007943 implant Substances 0.000 claims abstract description 276
- 239000000463 material Substances 0.000 claims abstract description 54
- 239000006249 magnetic particle Substances 0.000 claims abstract description 42
- 239000011159 matrix material Substances 0.000 claims abstract description 36
- 229920000249 biocompatible polymer Polymers 0.000 claims abstract description 33
- 230000004962 physiological condition Effects 0.000 claims abstract description 7
- 230000005291 magnetic effect Effects 0.000 claims description 223
- 210000001519 tissue Anatomy 0.000 claims description 153
- 230000004907 flux Effects 0.000 claims description 66
- 230000000087 stabilizing effect Effects 0.000 claims description 43
- 238000002513 implantation Methods 0.000 claims description 41
- 229920000642 polymer Polymers 0.000 claims description 36
- 210000003205 muscle Anatomy 0.000 claims description 29
- 239000003302 ferromagnetic material Substances 0.000 claims description 24
- 210000004877 mucosa Anatomy 0.000 claims description 18
- 210000000398 surgical flap Anatomy 0.000 claims description 18
- 210000003195 fascia Anatomy 0.000 claims description 16
- 210000004876 tela submucosa Anatomy 0.000 claims description 14
- 229920002379 silicone rubber Polymers 0.000 claims description 11
- 229920003023 plastic Polymers 0.000 claims description 9
- 239000004033 plastic Substances 0.000 claims description 9
- 239000002245 particle Substances 0.000 claims description 8
- 229920002635 polyurethane Polymers 0.000 claims description 8
- 239000004814 polyurethane Substances 0.000 claims description 8
- 229910000938 samarium–cobalt magnet Inorganic materials 0.000 claims description 7
- 229910001172 neodymium magnet Inorganic materials 0.000 claims description 6
- 239000004417 polycarbonate Substances 0.000 claims description 6
- 229920000515 polycarbonate Polymers 0.000 claims description 6
- 229910052761 rare earth metal Inorganic materials 0.000 claims description 6
- 150000002910 rare earth metals Chemical class 0.000 claims description 6
- 239000004945 silicone rubber Substances 0.000 claims description 6
- 230000001154 acute effect Effects 0.000 claims description 5
- 229910000828 alnico Inorganic materials 0.000 claims description 5
- 229910000859 α-Fe Inorganic materials 0.000 claims description 5
- 230000001737 promoting effect Effects 0.000 claims description 2
- 230000003213 activating effect Effects 0.000 claims 1
- 239000007779 soft material Substances 0.000 claims 1
- 238000009826 distribution Methods 0.000 description 21
- 230000006641 stabilisation Effects 0.000 description 17
- 238000011105 stabilization Methods 0.000 description 17
- 230000015572 biosynthetic process Effects 0.000 description 15
- 239000004568 cement Substances 0.000 description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 11
- 201000002859 sleep apnea Diseases 0.000 description 11
- 206010041235 Snoring Diseases 0.000 description 10
- 230000006870 function Effects 0.000 description 9
- 208000035475 disorder Diseases 0.000 description 8
- 239000003292 glue Substances 0.000 description 8
- 230000001681 protective effect Effects 0.000 description 8
- 208000008784 apnea Diseases 0.000 description 7
- 210000000214 mouth Anatomy 0.000 description 7
- 230000002829 reductive effect Effects 0.000 description 7
- 230000008901 benefit Effects 0.000 description 6
- 229910010293 ceramic material Inorganic materials 0.000 description 6
- 238000005520 cutting process Methods 0.000 description 6
- 239000004744 fabric Substances 0.000 description 6
- 230000005294 ferromagnetic effect Effects 0.000 description 6
- 210000003800 pharynx Anatomy 0.000 description 6
- 229920005989 resin Polymers 0.000 description 6
- 239000011347 resin Substances 0.000 description 6
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 5
- 239000002253 acid Substances 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000001356 surgical procedure Methods 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 229920001651 Cyanoacrylate Polymers 0.000 description 4
- 206010016654 Fibrosis Diseases 0.000 description 4
- MWCLLHOVUTZFKS-UHFFFAOYSA-N Methyl cyanoacrylate Chemical compound COC(=O)C(=C)C#N MWCLLHOVUTZFKS-UHFFFAOYSA-N 0.000 description 4
- 230000002745 absorbent Effects 0.000 description 4
- 239000002250 absorbent Substances 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 238000003491 array Methods 0.000 description 4
- 230000006378 damage Effects 0.000 description 4
- 230000000368 destabilizing effect Effects 0.000 description 4
- 238000006073 displacement reaction Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 230000004761 fibrosis Effects 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 230000000414 obstructive effect Effects 0.000 description 4
- 230000000241 respiratory effect Effects 0.000 description 4
- 239000000565 sealant Substances 0.000 description 4
- 238000002054 transplantation Methods 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 3
- 210000003484 anatomy Anatomy 0.000 description 3
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 238000002224 dissection Methods 0.000 description 3
- 210000002409 epiglottis Anatomy 0.000 description 3
- 238000003384 imaging method Methods 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 210000002741 palatine tonsil Anatomy 0.000 description 3
- -1 polytetrafluoroethylene Polymers 0.000 description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 3
- 239000004810 polytetrafluoroethylene Substances 0.000 description 3
- 210000001584 soft palate Anatomy 0.000 description 3
- 230000001629 suppression Effects 0.000 description 3
- 239000003106 tissue adhesive Substances 0.000 description 3
- 210000002396 uvula Anatomy 0.000 description 3
- 229910000531 Co alloy Inorganic materials 0.000 description 2
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 206010061533 Myotonia Diseases 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 208000031737 Tissue Adhesions Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000000845 anti-microbial effect Effects 0.000 description 2
- 239000012984 antibiotic solution Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 210000000133 brain stem Anatomy 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 230000001413 cellular effect Effects 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 230000007797 corrosion Effects 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000003292 diminished effect Effects 0.000 description 2
- 230000004064 dysfunction Effects 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000000017 hydrogel Substances 0.000 description 2
- 210000003823 hyoid bone Anatomy 0.000 description 2
- 230000003100 immobilizing effect Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 210000000867 larynx Anatomy 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000035772 mutation Effects 0.000 description 2
- 230000003204 osmotic effect Effects 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 239000004633 polyglycolic acid Substances 0.000 description 2
- 230000001846 repelling effect Effects 0.000 description 2
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 2
- 210000004872 soft tissue Anatomy 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 210000005070 sphincter Anatomy 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 229940075469 tissue adhesives Drugs 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 description 1
- LCSKNASZPVZHEG-UHFFFAOYSA-N 3,6-dimethyl-1,4-dioxane-2,5-dione;1,4-dioxane-2,5-dione Chemical group O=C1COC(=O)CO1.CC1OC(=O)C(C)OC1=O LCSKNASZPVZHEG-UHFFFAOYSA-N 0.000 description 1
- 206010001497 Agitation Diseases 0.000 description 1
- 229910000521 B alloy Inorganic materials 0.000 description 1
- SPFYMRJSYKOXGV-UHFFFAOYSA-N Baytril Chemical compound C1CN(CC)CCN1C(C(=C1)F)=CC2=C1C(=O)C(C(O)=O)=CN2C1CC1 SPFYMRJSYKOXGV-UHFFFAOYSA-N 0.000 description 1
- 108010006654 Bleomycin Proteins 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 208000003417 Central Sleep Apnea Diseases 0.000 description 1
- 229920004934 Dacron® Polymers 0.000 description 1
- 208000007590 Disorders of Excessive Somnolence Diseases 0.000 description 1
- 229910000976 Electrical steel Inorganic materials 0.000 description 1
- 229910017061 Fe Co Inorganic materials 0.000 description 1
- 229910000640 Fe alloy Inorganic materials 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 229930182566 Gentamicin Natural products 0.000 description 1
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 229910001209 Low-carbon steel Inorganic materials 0.000 description 1
- 206010052437 Nasal discomfort Diseases 0.000 description 1
- 229910052779 Neodymium Inorganic materials 0.000 description 1
- 229910000990 Ni alloy Inorganic materials 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 206010050028 Pharyngeal stenosis Diseases 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 229920000153 Povidone-iodine Polymers 0.000 description 1
- 206010038731 Respiratory tract irritation Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 108010023197 Streptokinase Proteins 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 description 1
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 description 1
- QVYYOKWPCQYKEY-UHFFFAOYSA-N [Fe].[Co] Chemical compound [Fe].[Co] QVYYOKWPCQYKEY-UHFFFAOYSA-N 0.000 description 1
- 229920006243 acrylic copolymer Polymers 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 229940105596 baytril Drugs 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 229920000229 biodegradable polyester Polymers 0.000 description 1
- 239000004622 biodegradable polyester Substances 0.000 description 1
- 229960001561 bleomycin Drugs 0.000 description 1
- OYVAGSVQBOHSSS-UAPAGMARSA-O bleomycin A2 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-UAPAGMARSA-O 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 229940106164 cephalexin Drugs 0.000 description 1
- ZAIPMKNFIOOWCQ-UEKVPHQBSA-N cephalexin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C)C(O)=O)=CC=CC=C1 ZAIPMKNFIOOWCQ-UEKVPHQBSA-N 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- KPLQYGBQNPPQGA-UHFFFAOYSA-N cobalt samarium Chemical compound [Co].[Sm] KPLQYGBQNPPQGA-UHFFFAOYSA-N 0.000 description 1
- 238000000748 compression moulding Methods 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- CGMRCMMOCQYHAD-UHFFFAOYSA-J dicalcium hydroxide phosphate Chemical compound [OH-].[Ca++].[Ca++].[O-]P([O-])([O-])=O CGMRCMMOCQYHAD-UHFFFAOYSA-J 0.000 description 1
- 229960004679 doxorubicin Drugs 0.000 description 1
- 229960003722 doxycycline Drugs 0.000 description 1
- XQTWDDCIUJNLTR-CVHRZJFOSA-N doxycycline monohydrate Chemical compound O.O=C1C2=C(O)C=CC=C2[C@H](C)[C@@H]2C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]1[C@H]2O XQTWDDCIUJNLTR-CVHRZJFOSA-N 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 229960002518 gentamicin Drugs 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 229960000318 kanamycin Drugs 0.000 description 1
- 229930027917 kanamycin Natural products 0.000 description 1
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 description 1
- 229930182823 kanamycin A Natural products 0.000 description 1
- 238000009940 knitting Methods 0.000 description 1
- 230000005415 magnetization Effects 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 229960004023 minocycline Drugs 0.000 description 1
- DYKFCLLONBREIL-KVUCHLLUSA-N minocycline Chemical compound C([C@H]1C2)C3=C(N(C)C)C=CC(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2[C@H](N(C)C)C(O)=C(C(N)=O)C1=O DYKFCLLONBREIL-KVUCHLLUSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004899 motility Effects 0.000 description 1
- 229910000595 mu-metal Inorganic materials 0.000 description 1
- 230000005405 multipole Effects 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- QEFYFXOXNSNQGX-UHFFFAOYSA-N neodymium atom Chemical compound [Nd] QEFYFXOXNSNQGX-UHFFFAOYSA-N 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 231100000822 oral exposure Toxicity 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 210000003254 palate Anatomy 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000006461 physiological response Effects 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920000052 poly(p-xylylene) Polymers 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 239000004626 polylactic acid Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229960001621 povidone-iodine Drugs 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004202 respiratory function Effects 0.000 description 1
- 210000003019 respiratory muscle Anatomy 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 229920005573 silicon-containing polymer Polymers 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 229910001961 silver nitrate Inorganic materials 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 229960000776 sodium tetradecyl sulfate Drugs 0.000 description 1
- UPUIQOIQVMNQAP-UHFFFAOYSA-M sodium;tetradecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCOS([O-])(=O)=O UPUIQOIQVMNQAP-UHFFFAOYSA-M 0.000 description 1
- 238000005476 soldering Methods 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 230000002966 stenotic effect Effects 0.000 description 1
- 229960005202 streptokinase Drugs 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 239000003894 surgical glue Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 238000003778 tissue fixation method Methods 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 238000007740 vapor deposition Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 238000009941 weaving Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
- A61F5/56—Devices for preventing snoring
- A61F5/566—Intra-oral devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
- A61F5/56—Devices for preventing snoring
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Transplantation (AREA)
- Nursing (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Prostheses (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Respiratory Apparatuses And Protective Means (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45616403P | 2003-03-20 | 2003-03-20 | |
| US10/656,861 US7188627B2 (en) | 2002-09-06 | 2003-09-06 | Magnetic force devices, systems, and methods for resisting tissue collapse within the pharyngeal conduit |
| US10/718,254 US7360542B2 (en) | 2002-09-06 | 2003-11-20 | Devices, systems, and methods to fixate tissue within the regions of body, such as the pharyngeal conduit |
| PCT/US2004/008635 WO2004084709A2 (en) | 2003-03-20 | 2004-03-22 | Devices, systems, and methods to fixate tissue within the regions of body, such as the pharyngeal conduit |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007075609A Division JP2007229485A (ja) | 2003-03-20 | 2007-03-22 | 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006523121A true JP2006523121A (ja) | 2006-10-12 |
| JP2006523121A5 JP2006523121A5 (enExample) | 2007-07-05 |
Family
ID=33102169
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507427A Pending JP2006523121A (ja) | 2003-03-20 | 2004-03-22 | 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 |
| JP2007075609A Pending JP2007229485A (ja) | 2003-03-20 | 2007-03-22 | 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007075609A Pending JP2007229485A (ja) | 2003-03-20 | 2007-03-22 | 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7360542B2 (enExample) |
| EP (1) | EP1613251B1 (enExample) |
| JP (2) | JP2006523121A (enExample) |
| AU (1) | AU2004224331A1 (enExample) |
| CA (1) | CA2519154A1 (enExample) |
| WO (1) | WO2004084709A2 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007229485A (ja) * | 2003-03-20 | 2007-09-13 | Apneon Inc | 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 |
| JP2010508889A (ja) * | 2006-11-03 | 2010-03-25 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 可動強磁性構造をもつ装置、システムおよび方法 |
| JP2010508893A (ja) * | 2006-11-03 | 2010-03-25 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 上気道における舌または舌骨筋に影響する磁力システムを使った装置、システムおよび方法 |
| JP2010530275A (ja) * | 2007-06-18 | 2010-09-09 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 目標組織領域における所望方向性を維持するための移植可能型デバイス、システム及び方法 |
Families Citing this family (175)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040267349A1 (en) * | 2003-06-27 | 2004-12-30 | Kobi Richter | Amorphous metal alloy medical devices |
| US8382821B2 (en) * | 1998-12-03 | 2013-02-26 | Medinol Ltd. | Helical hybrid stent |
| US7419949B2 (en) * | 2001-07-16 | 2008-09-02 | Novo Noridsk Healthcare A/G | Single-dose administration of factor VIIa |
| US7146981B2 (en) | 2002-02-04 | 2006-12-12 | Restore Medical, Inc. | Pharyngeal wall treatment |
| US7017582B2 (en) | 2002-02-04 | 2006-03-28 | Restore Medical Inc. | Stiffening pharyngeal wall treatment |
| US8590537B2 (en) | 2002-09-06 | 2013-11-26 | Koninklijke Philips N.V. | Devices, systems and methods using magnetic force systems in the tongue |
| US8047206B2 (en) | 2002-09-06 | 2011-11-01 | Koninklijke Philips Electronics N.V. | Magnetic devices, systems, and methods placed in or on a tongue |
| US8505539B2 (en) * | 2002-09-06 | 2013-08-13 | Koninklijke Philips N.V. | Devices, systems and methods using titrated magnetic force systems |
| CA2635955A1 (en) * | 2002-10-04 | 2004-04-22 | Pavad Medical, Inc. | System and method for preventing closure of passageways |
| US7965719B2 (en) * | 2002-12-11 | 2011-06-21 | Broadcom Corporation | Media exchange network supporting multiple broadband network and service provider infrastructures |
| US9039755B2 (en) | 2003-06-27 | 2015-05-26 | Medinol Ltd. | Helical hybrid stent |
| US9155639B2 (en) | 2009-04-22 | 2015-10-13 | Medinol Ltd. | Helical hybrid stent |
| US20050154412A1 (en) * | 2003-09-19 | 2005-07-14 | Restore Medical, Inc. | Airway implant and delivery tool |
| USD536792S1 (en) | 2003-09-19 | 2007-02-13 | Restore Medical, Inc. | Implant delivery tool |
| US7237554B2 (en) * | 2003-10-31 | 2007-07-03 | Restore Medical, Inc. | Airway implant |
| US7213599B2 (en) | 2003-10-31 | 2007-05-08 | Restore Medical, Inc. | Airway implant |
| AU2004289272A1 (en) * | 2003-11-05 | 2005-05-26 | Pavad Medical, Inc. | Altering the stiffness, size, and/or shape of tissues for breathing disorders and other conditions |
| EP2433593B1 (en) * | 2003-11-20 | 2020-07-15 | Koninklijke Philips N.V. | Devices, systems and methods to fixate tissue within the regions of body, such as the pharyngeal conduit |
| US8080014B2 (en) | 2004-12-15 | 2011-12-20 | Koninklijke Philips Electronics N.V. | System and method for hyoidplasty |
| US7955357B2 (en) | 2004-07-02 | 2011-06-07 | Ellipse Technologies, Inc. | Expandable rod system to treat scoliosis and method of using the same |
| US7285087B2 (en) * | 2004-07-15 | 2007-10-23 | Micardia Corporation | Shape memory devices and methods for reshaping heart anatomy |
| US7882842B2 (en) * | 2004-09-21 | 2011-02-08 | Pavad Medical, Inc. | Airway implant sensors and methods of making and using the same |
| US20090078275A1 (en) * | 2004-09-21 | 2009-03-26 | Pavad Medical, Inc. | Palatal Implant Fixation Devices and Methods |
| US8578937B2 (en) * | 2004-09-21 | 2013-11-12 | Medtronic Xomed, Inc. | Smart mandibular repositioning system |
| US8336553B2 (en) | 2004-09-21 | 2012-12-25 | Medtronic Xomed, Inc. | Auto-titration of positive airway pressure machine with feedback from implantable sensor |
| US7836888B2 (en) * | 2004-09-21 | 2010-11-23 | Pavad Medical, Incorporated | Airway implant and methods of making and using |
| US7980248B2 (en) * | 2004-09-21 | 2011-07-19 | Hegde Anant V | Delivery tools for sleep disorders treatment implant and methods of implantation |
| US20090038623A1 (en) * | 2004-09-21 | 2009-02-12 | Pavad Medical, Inc. | Inductive power transfer system for palatal implant |
| US8813753B2 (en) | 2004-09-21 | 2014-08-26 | Medtronic Xomed, Inc. | Implantable obstructive sleep apnea sensor |
| US20070144535A1 (en) * | 2004-09-21 | 2007-06-28 | Hegde Anant V | Implant for treatment of sleep disorders |
| US7997266B2 (en) * | 2004-10-04 | 2011-08-16 | Koninklijke Philips Electronics N.V. | System and method for airway manipulation |
| DE102005000702B4 (de) * | 2005-01-04 | 2007-08-23 | Klinikum Der Universität Regensburg | Vorrichtung zur mittigen Implantation in einen Zungenkörper |
| US7992567B2 (en) | 2005-02-08 | 2011-08-09 | Koninklijke Philips Electronics N.V. | System and method for percutaneous glossoplasty |
| US8096303B2 (en) | 2005-02-08 | 2012-01-17 | Koninklijke Philips Electronics N.V | Airway implants and methods and devices for insertion and retrieval |
| US8371307B2 (en) | 2005-02-08 | 2013-02-12 | Koninklijke Philips Electronics N.V. | Methods and devices for the treatment of airway obstruction, sleep apnea and snoring |
| US7322356B2 (en) * | 2005-02-24 | 2008-01-29 | Restore Medical, Inc. | Combination sleep apnea treatment |
| US7882840B2 (en) * | 2005-04-04 | 2011-02-08 | The Regents Of The University Of California | Passage expansion device for patients |
| US9265489B2 (en) | 2005-04-04 | 2016-02-23 | The Regents Of The University Of California | Swallow expansion device |
| US20060235380A1 (en) * | 2005-04-15 | 2006-10-19 | Restore Medical, Inc. | Tissue incision tool |
| US7337781B2 (en) * | 2005-04-15 | 2008-03-04 | Restore Medical, Inc. | Implant for tongue |
| US7644714B2 (en) | 2005-05-27 | 2010-01-12 | Apnex Medical, Inc. | Devices and methods for treating sleep disorders |
| US20070144534A1 (en) * | 2005-11-30 | 2007-06-28 | Carlos Mery | System to prevent airway obstruction |
| US20090173351A1 (en) * | 2006-04-20 | 2009-07-09 | Pavad Medical, Inc. | Control system for a tongue stabilization device |
| US7909037B2 (en) | 2006-04-20 | 2011-03-22 | Pavad Medical | Tethered airway implants and methods of using the same |
| US8256425B2 (en) | 2006-04-20 | 2012-09-04 | Medtronic Xomed, Inc. | Methods and devices for removal of a tongue stabilization device |
| US7909038B2 (en) | 2006-04-20 | 2011-03-22 | Pavad Medical, Inc. | Tongue stabilization device and methods of using the same |
| US7806900B2 (en) | 2006-04-26 | 2010-10-05 | Illuminoss Medical, Inc. | Apparatus and methods for delivery of reinforcing materials to bone |
| AU2007243353B2 (en) * | 2006-04-26 | 2012-05-31 | Illuminoss Medical, Inc. | Apparatus and methods for reinforcing bone |
| WO2007134005A1 (en) * | 2006-05-15 | 2007-11-22 | Mayo Foundation For Medical Education And Research | Devices and methods to treat nasal passages |
| US8517028B2 (en) * | 2006-06-23 | 2013-08-27 | Medtronic Xomed, Inc. | Stiffening procedure for sleep apnea |
| US7877142B2 (en) * | 2006-07-05 | 2011-01-25 | Micardia Corporation | Methods and systems for cardiac remodeling via resynchronization |
| MX2009002195A (es) * | 2006-08-30 | 2009-05-28 | David William Smith | Metodo para impartir una rigidez mono-axial o multi-axial a materiales extruidos y productos que resultan de los mismos. |
| US20080078412A1 (en) * | 2006-10-03 | 2008-04-03 | Restore Medical, Inc. | Tongue implant |
| US20080078411A1 (en) * | 2006-10-03 | 2008-04-03 | Restore Medical, Inc. | Tongue implant for sleep apnea |
| US7862502B2 (en) | 2006-10-20 | 2011-01-04 | Ellipse Technologies, Inc. | Method and apparatus for adjusting a gastrointestinal restriction device |
| US20080097517A1 (en) | 2006-10-23 | 2008-04-24 | Webtec Converting, Llc. | External Nasal Dilator and Methods of Manufacture |
| US20080108860A1 (en) * | 2006-11-02 | 2008-05-08 | Bell Stephen G | Methods and Apparatus for Magnetic Manipulation or Retrieval |
| US7879041B2 (en) | 2006-11-10 | 2011-02-01 | Illuminoss Medical, Inc. | Systems and methods for internal bone fixation |
| AU2007322320B2 (en) * | 2006-11-10 | 2013-02-14 | Illuminoss Medical, Inc. | Systems and methods for internal bone fixation |
| US9757585B2 (en) * | 2007-06-05 | 2017-09-12 | P Tech, Llc | Magnetic joint implant |
| US7658192B2 (en) * | 2007-07-03 | 2010-02-09 | Douglas C. Harrington | Method and device for treatment of obstructive sleep apnea |
| ATE505164T1 (de) * | 2007-10-19 | 2011-04-15 | Juergen Schmitt-Bylandt | System für die unterkiefer-protrusion zur verhinderung von schnarchen und apnoe |
| US20090112263A1 (en) | 2007-10-30 | 2009-04-30 | Scott Pool | Skeletal manipulation system |
| WO2009059090A1 (en) | 2007-10-31 | 2009-05-07 | Illuminoss Medical, Inc. | Light source |
| US20090165803A1 (en) * | 2007-11-01 | 2009-07-02 | Pavad Medical | On-off implant for supporting the tongue |
| US20090173352A1 (en) * | 2007-11-01 | 2009-07-09 | Pavad Medical | On-off implant for supporting the airway |
| US8403968B2 (en) | 2007-12-26 | 2013-03-26 | Illuminoss Medical, Inc. | Apparatus and methods for repairing craniomaxillofacial bones using customized bone plates |
| US8167787B2 (en) * | 2008-01-03 | 2012-05-01 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US20090248148A1 (en) | 2008-03-25 | 2009-10-01 | Ellipse Technologies, Inc. | Systems and methods for adjusting an annuloplasty ring with an integrated magnetic drive |
| US11202707B2 (en) | 2008-03-25 | 2021-12-21 | Nuvasive Specialized Orthopedics, Inc. | Adjustable implant system |
| US7954494B1 (en) | 2008-03-26 | 2011-06-07 | Connor Robert A | Device with actively-moving members that hold or move the tongue |
| WO2009140197A1 (en) | 2008-05-12 | 2009-11-19 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US9439801B2 (en) | 2012-06-29 | 2016-09-13 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US8425527B2 (en) | 2008-07-07 | 2013-04-23 | Medtronic Xomed, Inc. | Cavitation depth, perforation confirmation and implant delivery tool |
| US8678008B2 (en) * | 2008-07-30 | 2014-03-25 | Ethicon, Inc | Methods and devices for forming an auxiliary airway for treating obstructive sleep apnea |
| US8556797B2 (en) * | 2008-07-31 | 2013-10-15 | Ethicon, Inc. | Magnetic implants for treating obstructive sleep apnea and methods therefor |
| US8413661B2 (en) * | 2008-08-14 | 2013-04-09 | Ethicon, Inc. | Methods and devices for treatment of obstructive sleep apnea |
| US11241257B2 (en) | 2008-10-13 | 2022-02-08 | Nuvasive Specialized Orthopedics, Inc. | Spinal distraction system |
| US8561616B2 (en) | 2008-10-24 | 2013-10-22 | Ethicon, Inc. | Methods and devices for the indirect displacement of the hyoid bone for treating obstructive sleep apnea |
| US8561617B2 (en) | 2008-10-30 | 2013-10-22 | Ethicon, Inc. | Implant systems and methods for treating obstructive sleep apnea |
| US8382756B2 (en) | 2008-11-10 | 2013-02-26 | Ellipse Technologies, Inc. | External adjustment device for distraction device |
| IT1394518B1 (it) * | 2008-11-11 | 2012-07-05 | Gemini Group S R L | Dispositivo combinato per la terapia con la tecnica dei magneti |
| US8783258B2 (en) | 2008-12-01 | 2014-07-22 | Ethicon, Inc. | Implant systems and methods for treating obstructive sleep apnea |
| US8800567B2 (en) | 2008-12-01 | 2014-08-12 | Ethicon, Inc. | Implant systems and methods for treating obstructive sleep apnea |
| CA2746218A1 (en) * | 2008-12-09 | 2010-06-17 | H-Medical | Apparatus, systems, and methods for constraining and/or supporting tissue structures along an airway |
| US8371308B2 (en) | 2009-02-17 | 2013-02-12 | Ethicon, Inc. | Magnetic implants and methods for treating an oropharyngeal condition |
| US8555891B2 (en) * | 2009-02-18 | 2013-10-15 | Medtronic Xomed, Inc. | Implant system for controlling airway passage |
| US8197490B2 (en) | 2009-02-23 | 2012-06-12 | Ellipse Technologies, Inc. | Non-invasive adjustable distraction system |
| US8307831B2 (en) | 2009-03-16 | 2012-11-13 | Ethicon, Inc. | Implant systems and methods for treating obstructive sleep apnea |
| US8210729B2 (en) | 2009-04-06 | 2012-07-03 | Illuminoss Medical, Inc. | Attachment system for light-conducting fibers |
| US8512338B2 (en) * | 2009-04-07 | 2013-08-20 | Illuminoss Medical, Inc. | Photodynamic bone stabilization systems and methods for reinforcing bone |
| US9622792B2 (en) | 2009-04-29 | 2017-04-18 | Nuvasive Specialized Orthopedics, Inc. | Interspinous process device and method |
| EP2467098A4 (en) | 2009-08-19 | 2015-07-08 | Illuminoss Medical Inc | DEVICES AND METHODS FOR BONE ALIGNMENT, STABILIZATION AND DISTRACTION |
| RU2016101629A (ru) | 2009-09-04 | 2018-12-04 | Нувэйсив Спешилайзд Ортопэдикс, Инк. | Устройство и способ для наращивания кости |
| US10172669B2 (en) | 2009-10-09 | 2019-01-08 | Ethicon Llc | Surgical instrument comprising an energy trigger lockout |
| US9326886B2 (en) | 2009-10-29 | 2016-05-03 | Ethicon, Inc. | Fluid filled implants for treating obstructive sleep apnea |
| US9877862B2 (en) | 2009-10-29 | 2018-01-30 | Ethicon, Inc. | Tongue suspension system with hyoid-extender for treating obstructive sleep apnea |
| US9974683B2 (en) * | 2009-10-30 | 2018-05-22 | Ethicon, Inc. | Flexible implants having internal volume shifting capabilities for treating obstructive sleep apnea |
| US8632488B2 (en) * | 2009-12-15 | 2014-01-21 | Ethicon, Inc. | Fluid filled implants for treating medical conditions |
| EP2547297A4 (en) | 2010-03-19 | 2014-08-06 | Revent Medical Inc | SYSTEMS AND METHODS FOR TREATING SLEEP APNEA |
| CA2793213A1 (en) | 2010-03-19 | 2011-09-22 | Revent Medical Inc. | Systems and methods for treatment of sleep apnea |
| JP2013526392A (ja) | 2010-05-21 | 2013-06-24 | レベント メディカル インコーポレイテッド | 睡眠時無呼吸を治療するためのシステム及び方法 |
| GB2480498A (en) | 2010-05-21 | 2011-11-23 | Ethicon Endo Surgery Inc | Medical device comprising RF circuitry |
| US8684965B2 (en) | 2010-06-21 | 2014-04-01 | Illuminoss Medical, Inc. | Photodynamic bone stabilization and drug delivery systems |
| US9248043B2 (en) | 2010-06-30 | 2016-02-02 | Ellipse Technologies, Inc. | External adjustment device for distraction device |
| JP2013538075A (ja) | 2010-07-26 | 2013-10-10 | レベント メディカル インコーポレイテッド | 睡眠時無呼吸を治療するためのシステム及び方法 |
| US8734488B2 (en) | 2010-08-09 | 2014-05-27 | Ellipse Technologies, Inc. | Maintenance feature in magnetic implant |
| US8844537B1 (en) | 2010-10-13 | 2014-09-30 | Michael T. Abramson | System and method for alleviating sleep apnea |
| WO2012088432A1 (en) | 2010-12-22 | 2012-06-28 | Illuminoss Medical, Inc. | Systems and methods for treating conditions and diseases of the spine |
| US8715282B2 (en) | 2011-02-14 | 2014-05-06 | Ellipse Technologies, Inc. | System and method for altering rotational alignment of bone sections |
| WO2013010169A1 (en) | 2011-07-14 | 2013-01-17 | Cook Medical Technologies Llc | A sling to be used in the treatment of obstructive sleep apnea |
| BR112014001078A2 (pt) | 2011-07-19 | 2017-02-21 | Illuminoss Medical Inc | dispositivos e métodos para reestruturação e estabilização óssea |
| US8905033B2 (en) | 2011-09-28 | 2014-12-09 | Ethicon, Inc. | Modular tissue securement systems |
| US10743794B2 (en) | 2011-10-04 | 2020-08-18 | Nuvasive Specialized Orthopedics, Inc. | Devices and methods for non-invasive implant length sensing |
| WO2013059609A1 (en) | 2011-10-19 | 2013-04-25 | Illuminoss Medical, Inc. | Systems and methods for joint stabilization |
| US9161855B2 (en) | 2011-10-24 | 2015-10-20 | Ethicon, Inc. | Tissue supporting device and method |
| US20130123776A1 (en) | 2011-10-24 | 2013-05-16 | Ethicon Endo-Surgery, Inc. | Battery shut-off algorithm in a battery powered device |
| US10016220B2 (en) | 2011-11-01 | 2018-07-10 | Nuvasive Specialized Orthopedics, Inc. | Adjustable magnetic devices and methods of using same |
| US8973582B2 (en) | 2011-11-30 | 2015-03-10 | Ethicon, Inc. | Tongue suspension device and method |
| US10470760B2 (en) | 2011-12-08 | 2019-11-12 | Ethicon, Inc. | Modified tissue securement fibers |
| US9173766B2 (en) | 2012-06-01 | 2015-11-03 | Ethicon, Inc. | Systems and methods to treat upper pharyngeal airway of obstructive sleep apnea patients |
| US20130338714A1 (en) | 2012-06-15 | 2013-12-19 | Arvin Chang | Magnetic implants with improved anatomical compatibility |
| US8939977B2 (en) | 2012-07-10 | 2015-01-27 | Illuminoss Medical, Inc. | Systems and methods for separating bone fixation devices from introducer |
| WO2014189540A1 (en) | 2012-10-16 | 2014-11-27 | Catalano Peter J | Method and apparatus for treating obstructive sleep apnea (osa) |
| US9044281B2 (en) | 2012-10-18 | 2015-06-02 | Ellipse Technologies, Inc. | Intramedullary implants for replacing lost bone |
| US10130405B2 (en) | 2012-10-29 | 2018-11-20 | Nuvasive Specialized Orthopedics, Inc. | Adjustable devices for treating arthritis of the knee |
| US9687281B2 (en) | 2012-12-20 | 2017-06-27 | Illuminoss Medical, Inc. | Distal tip for bone fixation devices |
| US9179938B2 (en) | 2013-03-08 | 2015-11-10 | Ellipse Technologies, Inc. | Distraction devices and method of assembling the same |
| US10123900B2 (en) | 2013-03-15 | 2018-11-13 | Cook Medical Technologies Llc | Devices, kits, and methods for the treatment of obstructive sleep apnea |
| US10226242B2 (en) | 2013-07-31 | 2019-03-12 | Nuvasive Specialized Orthopedics, Inc. | Noninvasively adjustable suture anchors |
| CA2919504A1 (en) | 2013-08-01 | 2015-02-05 | Christine BRONIKOWSKI | Tissue adjustment implant |
| AU2014306232B2 (en) | 2013-08-05 | 2018-12-06 | C2Dx, Inc. | Medical devices having a releasable tubular member and methods of using the same |
| US9801734B1 (en) | 2013-08-09 | 2017-10-31 | Nuvasive, Inc. | Lordotic expandable interbody implant |
| US10751094B2 (en) | 2013-10-10 | 2020-08-25 | Nuvasive Specialized Orthopedics, Inc. | Adjustable spinal implant |
| US9956384B2 (en) | 2014-01-24 | 2018-05-01 | Cook Medical Technologies Llc | Articulating balloon catheter and method for using the same |
| EP3137000B1 (en) | 2014-04-28 | 2023-08-23 | NuVasive Specialized Orthopedics, Inc. | System for informational magnetic feedback in adjustable implants |
| US9974563B2 (en) | 2014-05-28 | 2018-05-22 | Cook Medical Technologies Llc | Medical devices having a releasable member and methods of using the same |
| US9913661B2 (en) | 2014-08-04 | 2018-03-13 | Cook Medical Technologies Llc | Medical devices having a releasable tubular member and methods of using the same |
| EP3209226B1 (en) | 2014-10-23 | 2020-11-25 | NuVasive Specialized Orthopedics, Inc. | Remotely adjustable interactive bone reshaping implant |
| CN105748187B (zh) * | 2014-12-19 | 2017-12-01 | 张湘民 | 咽侧壁牵引装置和植入方法 |
| US10159524B2 (en) | 2014-12-22 | 2018-12-25 | Ethicon Llc | High power battery powered RF amplifier topology |
| JP6847341B2 (ja) | 2014-12-26 | 2021-03-24 | ニューベイシブ スペシャライズド オーソペディックス,インコーポレイテッド | 伸延のためのシステム及び方法 |
| US10238427B2 (en) | 2015-02-19 | 2019-03-26 | Nuvasive Specialized Orthopedics, Inc. | Systems and methods for vertebral adjustment |
| US10314638B2 (en) | 2015-04-07 | 2019-06-11 | Ethicon Llc | Articulating radio frequency (RF) tissue seal with articulating state sensing |
| JP6833808B2 (ja) * | 2015-08-03 | 2021-02-24 | オーベンタス・メディカル・リミテッドOventus Medical Limited | 呼吸補助装置 |
| US10959771B2 (en) | 2015-10-16 | 2021-03-30 | Ethicon Llc | Suction and irrigation sealing grasper |
| WO2017066774A1 (en) | 2015-10-16 | 2017-04-20 | Nuvasive Specialized Orthopedics, Inc. | Adjustable devices for treating arthritis of the knee |
| AU2016368167B2 (en) | 2015-12-10 | 2021-04-22 | Nuvasive Specialized Orthopedics, Inc. | External adjustment device for distraction device |
| US10959806B2 (en) | 2015-12-30 | 2021-03-30 | Ethicon Llc | Energized medical device with reusable handle |
| CN108882953B (zh) | 2016-01-28 | 2021-09-03 | 诺威适骨科专科公司 | 骨搬移用的系统 |
| WO2017139548A1 (en) | 2016-02-10 | 2017-08-17 | Nuvasive Specialized Orthopedics, Inc. | Systems and methods for controlling multiple surgical variables |
| US10856934B2 (en) | 2016-04-29 | 2020-12-08 | Ethicon Llc | Electrosurgical instrument with electrically conductive gap setting and tissue engaging members |
| US10987156B2 (en) | 2016-04-29 | 2021-04-27 | Ethicon Llc | Electrosurgical instrument with electrically conductive gap setting member and electrically insulative tissue engaging members |
| US10751117B2 (en) | 2016-09-23 | 2020-08-25 | Ethicon Llc | Electrosurgical instrument with fluid diverter |
| US11033325B2 (en) | 2017-02-16 | 2021-06-15 | Cilag Gmbh International | Electrosurgical instrument with telescoping suction port and debris cleaner |
| US10799284B2 (en) | 2017-03-15 | 2020-10-13 | Ethicon Llc | Electrosurgical instrument with textured jaws |
| US11497546B2 (en) | 2017-03-31 | 2022-11-15 | Cilag Gmbh International | Area ratios of patterned coatings on RF electrodes to reduce sticking |
| US10603117B2 (en) | 2017-06-28 | 2020-03-31 | Ethicon Llc | Articulation state detection mechanisms |
| AU2018294247A1 (en) | 2017-06-29 | 2020-01-23 | Cook Biotech Incorporated | Implantable medical devices for tissue repositioning |
| US11490951B2 (en) | 2017-09-29 | 2022-11-08 | Cilag Gmbh International | Saline contact with electrodes |
| US11484358B2 (en) | 2017-09-29 | 2022-11-01 | Cilag Gmbh International | Flexible electrosurgical instrument |
| US11033323B2 (en) | 2017-09-29 | 2021-06-15 | Cilag Gmbh International | Systems and methods for managing fluid and suction in electrosurgical systems |
| WO2020006239A1 (en) | 2018-06-27 | 2020-01-02 | Illuminoss Medical, Inc. | Systems and methods for bone stabilization and fixation |
| EP3884162B1 (de) * | 2018-11-23 | 2023-12-20 | HNP Mikrosysteme GmbH | Dichtstruktur für eine transportvorrichtung mit formgedächtnislegierung |
| WO2020163792A1 (en) | 2019-02-07 | 2020-08-13 | 171Nuvasive Specialized Orthopedics, Inc. | Ultrasonic communication in medical devices |
| US11589901B2 (en) | 2019-02-08 | 2023-02-28 | Nuvasive Specialized Orthopedics, Inc. | External adjustment device |
| WO2021115562A1 (de) | 2019-12-10 | 2021-06-17 | Medartis Holding Ag | Vorrichtung und verfahren zum stechen eines weichteilkanals in einem körperteil und implantat zum einsetzen in einen weichteilkanal in einem körperteil |
| US12478488B2 (en) | 2020-02-19 | 2025-11-25 | Medinol Ltd. | Helical stent with enhanced crimping |
| WO2022055678A1 (en) | 2020-09-08 | 2022-03-17 | Nuvasive Specialized Orthopedics, Inc. | Remote control module for adjustable implants |
| US12471982B2 (en) | 2020-12-02 | 2025-11-18 | Cilag Gmbh International | Method for tissue treatment by surgical instrument |
| US12004784B2 (en) | 2021-02-23 | 2024-06-11 | Nuvasive Specialized Orthopedics, Inc. | Adjustable implant, system and methods |
| US11737787B1 (en) | 2021-05-27 | 2023-08-29 | Nuvasive, Inc. | Bone elongating devices and methods of use |
| EP4380480A1 (en) | 2021-08-03 | 2024-06-12 | NuVasive Specialized Orthopedics, Inc. | Adjustable implant |
| US11957342B2 (en) | 2021-11-01 | 2024-04-16 | Cilag Gmbh International | Devices, systems, and methods for detecting tissue and foreign objects during a surgical operation |
| US12458417B2 (en) | 2022-08-15 | 2025-11-04 | Nuvasive Specialized Orthopedics Inc. | Intermedullary lengthening implant with integrated load sensor |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4978323A (en) * | 1989-08-10 | 1990-12-18 | George Freedman | System and method for preventing closure of passageways |
| US5019372A (en) * | 1986-06-27 | 1991-05-28 | The Children's Medical Center Corporation | Magnetically modulated polymeric drug release system |
| JPH03188601A (ja) * | 1989-12-18 | 1991-08-16 | Shin Etsu Polymer Co Ltd | Nd―Fe―B系プラスチック磁石組成物 |
| JP2007229485A (ja) * | 2003-03-20 | 2007-09-13 | Apneon Inc | 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4304227A (en) | 1978-03-03 | 1981-12-08 | Samelson Charles F | Device for treatment of snoring, bruxism or for avoidance of sleep apnea |
| US5220918A (en) | 1988-11-16 | 1993-06-22 | Smith & Nephew Richards, Inc. | Trans-tympanic connector for magnetic induction hearing aid |
| US5176618A (en) * | 1989-08-10 | 1993-01-05 | George Freedman | System for preventing closure of passageways |
| US5284161A (en) | 1992-11-12 | 1994-02-08 | Karell Manuel L | Snopper-the snoring stopper anti-snoring mouth device |
| DE4307262A1 (de) * | 1993-03-02 | 1994-09-08 | Christian Bergemann | Magnetisches polymeres Siliciumdioxid |
| US5373859A (en) | 1993-04-19 | 1994-12-20 | Forney; Leroy S. | Tongue positioning device |
| US5649540A (en) | 1994-01-12 | 1997-07-22 | Snorex, Inc. | Tongue positioning device for medical procedures |
| US5465734A (en) | 1994-01-12 | 1995-11-14 | Snorex, Inc. | Adjustable tongue positioning device and method |
| US5792067A (en) | 1995-11-21 | 1998-08-11 | Karell; Manuel L. | Apparatus and method for mitigating sleep and other disorders through electromuscular stimulation |
| US5979456A (en) * | 1996-04-22 | 1999-11-09 | Magovern; George J. | Apparatus and method for reversibly reshaping a body part |
| US5988171A (en) | 1997-06-26 | 1999-11-23 | Influence Medical Technologies, Ltd. | Methods and devices for the treatment of airway obstruction, sleep apnea and snoring |
| US6231496B1 (en) | 1999-07-07 | 2001-05-15 | Peter J. Wilk | Medical treatment method |
| US6415796B1 (en) | 1999-09-17 | 2002-07-09 | Pi Medical, Inc. | Placement tool for snoring treatment |
| US6450169B1 (en) | 1999-09-17 | 2002-09-17 | Pi Medical, Inc. | Braided implant for snoring treatment |
| US6431174B1 (en) | 2000-08-10 | 2002-08-13 | Pi Medical, Inc. | Method and apparatus to treat conditions of the naso-pharyngeal area |
| US6390096B1 (en) | 1999-09-17 | 2002-05-21 | Pi Medical, Inc. | Needle with pre-loaded implant for snoring treatment |
| US6250307B1 (en) * | 1999-09-17 | 2001-06-26 | Pi Medical, Inc. | Snoring treatment |
| US6523541B2 (en) | 1999-09-17 | 2003-02-25 | Pi Medical, Inc. | Delivery system for snoring treatment implant and method |
| US6636767B1 (en) | 1999-09-29 | 2003-10-21 | Restore Medical, Inc. | Implanatable stimulation device for snoring treatment |
| US6408851B1 (en) | 1999-10-01 | 2002-06-25 | Manuel L. Karell | Method and device for holding a tongue in a forward position |
| US6244865B1 (en) | 1999-12-06 | 2001-06-12 | Sensormedics Corporation | Tongue positioning device with optional filter |
| US6877513B2 (en) | 2000-01-21 | 2005-04-12 | Respironics, Inc. | Intraoral apparatus for enhancing airway patency |
| US6490885B1 (en) | 2000-05-16 | 2002-12-10 | Jjk Industries, L.P. | Energized body jewelry and accessories |
| US7073505B2 (en) | 2002-09-06 | 2006-07-11 | Apneon, Inc. | Systems and methods for moving and/or restraining tissue in the oral cavity |
| US6955172B2 (en) | 2002-09-06 | 2005-10-18 | Apneon, Inc. | Systems and methods for moving and/or restraining the tongue in the oral cavity |
| CA2635955A1 (en) | 2002-10-04 | 2004-04-22 | Pavad Medical, Inc. | System and method for preventing closure of passageways |
| US7237554B2 (en) | 2003-10-31 | 2007-07-03 | Restore Medical, Inc. | Airway implant |
-
2003
- 2003-11-20 US US10/718,254 patent/US7360542B2/en not_active Expired - Lifetime
-
2004
- 2004-03-22 JP JP2006507427A patent/JP2006523121A/ja active Pending
- 2004-03-22 WO PCT/US2004/008635 patent/WO2004084709A2/en not_active Ceased
- 2004-03-22 CA CA002519154A patent/CA2519154A1/en not_active Abandoned
- 2004-03-22 EP EP04757970A patent/EP1613251B1/en not_active Expired - Lifetime
- 2004-03-22 AU AU2004224331A patent/AU2004224331A1/en not_active Abandoned
-
2007
- 2007-03-22 JP JP2007075609A patent/JP2007229485A/ja active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5019372A (en) * | 1986-06-27 | 1991-05-28 | The Children's Medical Center Corporation | Magnetically modulated polymeric drug release system |
| US4978323A (en) * | 1989-08-10 | 1990-12-18 | George Freedman | System and method for preventing closure of passageways |
| JPH03188601A (ja) * | 1989-12-18 | 1991-08-16 | Shin Etsu Polymer Co Ltd | Nd―Fe―B系プラスチック磁石組成物 |
| JP2007229485A (ja) * | 2003-03-20 | 2007-09-13 | Apneon Inc | 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007229485A (ja) * | 2003-03-20 | 2007-09-13 | Apneon Inc | 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 |
| JP2010508889A (ja) * | 2006-11-03 | 2010-03-25 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 可動強磁性構造をもつ装置、システムおよび方法 |
| JP2010508893A (ja) * | 2006-11-03 | 2010-03-25 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 上気道における舌または舌骨筋に影響する磁力システムを使った装置、システムおよび方法 |
| JP2010530275A (ja) * | 2007-06-18 | 2010-09-09 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 目標組織領域における所望方向性を維持するための移植可能型デバイス、システム及び方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2519154A1 (en) | 2004-10-07 |
| AU2004224331A1 (en) | 2004-10-07 |
| WO2004084709A2 (en) | 2004-10-07 |
| EP1613251B1 (en) | 2010-01-13 |
| US20050284485A9 (en) | 2005-12-29 |
| EP1613251A4 (en) | 2006-12-13 |
| WO2004084709A3 (en) | 2005-01-27 |
| US20040149290A1 (en) | 2004-08-05 |
| JP2007229485A (ja) | 2007-09-13 |
| EP1613251A2 (en) | 2006-01-11 |
| US7360542B2 (en) | 2008-04-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006523121A (ja) | 閉塞型睡眠時無呼吸を含む睡眠時呼吸障害の治療のために目標身体部域内たとえば咽頭管内の組織を固定もしくは支持する装置、システムならびに方法 | |
| US7441559B2 (en) | Devices, systems, and methods to fixate tissue within the regions of body, such as the pharyngeal conduit | |
| JP5266360B2 (ja) | 咽頭管内の組織崩壊に抵抗する磁力デバイス、システム、および方法 | |
| EP2363102B1 (en) | Magnetic force devices, systems, and methods for resisting tissue collapse within the pharyngeal conduit | |
| US7958895B2 (en) | Magnetic force devices, systems, and methods for resisting tissue collapse within the pharyngeal conduit | |
| US7481224B2 (en) | Magnetic force device, systems, and methods for resisting tissue collapse within the pharyngeal conduit | |
| CN100435761C (zh) | 治疗打鼾的植入物和方法 | |
| US7047979B2 (en) | Soft palate implant with fiber construction | |
| JP2006508708A5 (enExample) | ||
| JP2004529690A (ja) | いびき治療のための編まれた口蓋用埋め込み物 | |
| CA2545651A1 (en) | Devices systems, and methods to fixate tissue within the regions of the body, such as the pharyngeal conduit | |
| CN101528163A (zh) | 稳定的磁力设备、系统和方法 | |
| JP2009517131A (ja) | 体内または身体上で使用される磁力デバイスの安定または固定のためのデバイス、システムおよび方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070322 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20070517 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090805 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20100930 |