JP2006522819A5 - - Google Patents
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- Publication number
- JP2006522819A5 JP2006522819A5 JP2006509866A JP2006509866A JP2006522819A5 JP 2006522819 A5 JP2006522819 A5 JP 2006522819A5 JP 2006509866 A JP2006509866 A JP 2006509866A JP 2006509866 A JP2006509866 A JP 2006509866A JP 2006522819 A5 JP2006522819 A5 JP 2006522819A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally
- peripheral opioid
- formulation
- opioid antagonist
- sustained release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46158503P | 2003-04-08 | 2003-04-08 | |
| PCT/US2004/010998 WO2004091665A1 (en) | 2003-04-08 | 2004-04-08 | Combination therapy for constipation comprising a laxative and a peripheral opioid antagonist |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006522819A JP2006522819A (ja) | 2006-10-05 |
| JP2006522819A5 true JP2006522819A5 (enExample) | 2007-05-31 |
Family
ID=33299838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509866A Pending JP2006522819A (ja) | 2003-04-08 | 2004-04-08 | 緩下薬および末梢オピオイドアンタゴニストを組み合わせた便秘の組み合わせ療法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040259899A1 (enExample) |
| EP (1) | EP1638607A1 (enExample) |
| JP (1) | JP2006522819A (enExample) |
| CN (1) | CN1767855A (enExample) |
| AU (1) | AU2004229464A1 (enExample) |
| BR (1) | BRPI0409125A (enExample) |
| CA (1) | CA2521420A1 (enExample) |
| MX (1) | MXPA05010821A (enExample) |
| RU (1) | RU2005134364A (enExample) |
| WO (1) | WO2004091665A1 (enExample) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6274591B1 (en) * | 1997-11-03 | 2001-08-14 | Joseph F. Foss | Use of methylnaltrexone and related compounds |
| US20030158220A1 (en) * | 1997-11-03 | 2003-08-21 | Foss Joseph F. | Use of methylnaltrexone and related compounds to treat chronic opioid use side effects |
| US20090149479A1 (en) * | 1998-11-02 | 2009-06-11 | Elan Pharma International Limited | Dosing regimen |
| BRPI0409133B8 (pt) | 2003-04-08 | 2021-05-25 | Progenics Pharm Inc | preparações farmacêuticas estavéis compreendendo metilnaltrexona |
| EP1617846A1 (en) * | 2003-04-08 | 2006-01-25 | Progenics Pharmaceuticals, Inc. | The use of peripheral opiois antagonists, especially methylnaltrexone to treat irritable bowel syndrome |
| US20040202717A1 (en) | 2003-04-08 | 2004-10-14 | Mehta Atul M. | Abuse-resistant oral dosage forms and method of use thereof |
| SG173326A1 (en) * | 2004-06-04 | 2011-08-29 | Camurus Ab | Liquid depot formulations |
| EP1845989A1 (en) * | 2005-01-20 | 2007-10-24 | Progenics Pharmaceuticals, Inc. | Use of methylnaltrexone and related compounds to treat post-operative gastrointestinal dysfunction |
| BRPI0608818A2 (pt) | 2005-03-07 | 2010-01-26 | Univ Chicago | uso de antagonista opióides para atenuação de proliferação e migração de células endoteliais |
| US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US8524731B2 (en) | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
| EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
| US8802183B2 (en) | 2005-04-28 | 2014-08-12 | Proteus Digital Health, Inc. | Communication system with enhanced partial power source and method of manufacturing same |
| AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| US20080194611A1 (en) * | 2005-06-03 | 2008-08-14 | Alverdy John C | Modulation of Cell Barrier Dysfunction |
| US20070185145A1 (en) * | 2006-02-03 | 2007-08-09 | Royds Robert B | Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same |
| GB0613925D0 (en) * | 2006-07-13 | 2006-08-23 | Unilever Plc | Improvements relating to nanodispersions |
| TWI489984B (zh) | 2006-08-04 | 2015-07-01 | Wyeth Corp | 用於非經腸道傳輸化合物之配方及其用途 |
| DE102006044694A1 (de) * | 2006-09-22 | 2008-03-27 | Krewel Meuselbach Gmbh | Perorale feste Schmerzmittelzubereitung |
| JP5916277B2 (ja) | 2006-10-25 | 2016-05-11 | プロテウス デジタル ヘルス, インコーポレイテッド | 摂取可能な制御活性化識別子 |
| PT2139890E (pt) | 2007-03-29 | 2014-09-03 | Wyeth Llc | Antagonistas do receptor opióide periférico e respectivas utilizações |
| CA2682125C (en) | 2007-03-29 | 2015-06-16 | Progenics Pharmaceuticals, Inc. | Peripheral opioid receptor antagonists and uses thereof |
| EP2134718A2 (en) | 2007-03-29 | 2009-12-23 | Progenics Pharmaceuticals, Inc. | Crystal forms of (r)-n-methylnaltrexone bromide and uses thereof |
| MX2010001629A (es) | 2007-08-10 | 2010-08-09 | Alessandro Sannino | Hidrogeles de polimero y metodos de preparacion de los mismos. |
| US8623418B2 (en) * | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
| CA2713568C (en) | 2008-02-06 | 2016-09-20 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
| AU2009225434B2 (en) | 2008-03-21 | 2014-05-22 | The University Of Chicago | Treatment with opioid antagonists and mTOR inhibitors |
| EP2306829B1 (en) * | 2008-07-01 | 2017-01-04 | University of Chicago | Particles containing a peripheral opioid receptor antagonist |
| SG195535A1 (en) | 2008-07-08 | 2013-12-30 | Proteus Digital Health Inc | Ingestible event marker data framework |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| TWI449685B (zh) * | 2008-12-10 | 2014-08-21 | Theravance Inc | 3-羧基丙基-胺基四氫化萘化合物之結晶型 |
| BR122013009559A2 (pt) | 2009-04-28 | 2019-08-06 | Proteus Digital Health, Inc. | Marcadores de evento de ingerível altamente confiável e métodos para usar os mesmos |
| US20100317682A1 (en) * | 2009-06-11 | 2010-12-16 | Richard Fuisz | Single Dosage Unit Including Opioid and Methylnaltrexone or Methylnaltrexone Salt |
| US8829020B2 (en) | 2009-07-16 | 2014-09-09 | Mallinckrodt Llc | Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers |
| TWI517050B (zh) | 2009-11-04 | 2016-01-11 | 普羅托斯數位健康公司 | 供應鏈管理之系統 |
| AU2016200133B2 (en) * | 2010-03-11 | 2017-09-07 | Wyeth Llc | Oral formulations and lipophilic salts of methylnaltrexone |
| KR101982482B1 (ko) * | 2010-03-11 | 2019-05-27 | 와이어쓰 엘엘씨 | 메틸날트렉손의 경구 제형 및 친유성 염 |
| AU2013203559B2 (en) * | 2010-03-11 | 2015-12-03 | Wyeth Llc | Oral formulations and lipophilic salts of methylnaltrexone |
| RU2012143791A (ru) | 2010-04-07 | 2014-05-20 | Проутьюс Диджитал Хэлс, Инк. | Миниатюрное проглатываемое устройство |
| JP5840201B2 (ja) | 2010-05-10 | 2016-01-06 | ユーロ−セルティーク エス.エイ. | 活性剤を負荷した顆粒と追加の活性剤の組合せ |
| NZ700732A (en) | 2010-05-10 | 2015-08-28 | Euro Celtique Sa | Pharmaceutical compositions comprising hydromorphone and naloxone |
| ES2642788T3 (es) | 2010-05-10 | 2017-11-20 | Euro-Celtique S.A. | Fabricación de gránulos sin principio activo y de comprimidos que comprenden los mismos |
| EP2632578A4 (en) * | 2010-10-29 | 2014-12-03 | Msd Consumer Care Inc | CONCENTRATED THERAPEUTIC SOLUTION |
| JP2014504902A (ja) | 2010-11-22 | 2014-02-27 | プロテウス デジタル ヘルス, インコーポレイテッド | 医薬品を有する摂取可能なデバイス |
| AU2011342368B2 (en) * | 2010-12-13 | 2016-11-17 | Rite-Prep Pty Ltd | Gastric and colonic formulations and methods for making and using them |
| CN102641496A (zh) | 2011-02-16 | 2012-08-22 | 辛绍祺 | 高分子聚合物的新用途及其组成物 |
| PL395069A1 (pl) * | 2011-05-31 | 2012-12-03 | Warszawski Uniwersytet Medyczny | Przeciwbólowa kompozycja farmaceutyczna do podawania doustnego |
| WO2015112603A1 (en) | 2014-01-21 | 2015-07-30 | Proteus Digital Health, Inc. | Masticable ingestible product and communication system therefor |
| US20180326069A1 (en) * | 2011-10-24 | 2018-11-15 | Bayer Healthcare Llc | Therapeutic solution concentrate |
| PL2877155T3 (pl) | 2012-07-26 | 2021-05-17 | Camurus Ab | Formulacje opioidowe |
| LT2877155T (lt) | 2012-07-26 | 2021-02-25 | Camurus Ab | Opioidų vaisto formos |
| US10166219B2 (en) | 2012-07-27 | 2019-01-01 | Redhill Bipharma Ltd. | Formulations and methods of manufacturing formulations for use in colonic evacuation |
| TWI659994B (zh) | 2013-01-29 | 2019-05-21 | 美商普羅托斯數位健康公司 | 高度可膨脹之聚合型薄膜及包含彼之組成物 |
| US10175376B2 (en) | 2013-03-15 | 2019-01-08 | Proteus Digital Health, Inc. | Metal detector apparatus, system, and method |
| WO2014197402A1 (en) | 2013-06-04 | 2014-12-11 | Proteus Digital Health, Inc. | System, apparatus and methods for data collection and assessing outcomes |
| US20160151296A1 (en) * | 2013-05-22 | 2016-06-02 | Empire Technology Development Llc | Long delayed release laxative |
| US9796576B2 (en) | 2013-08-30 | 2017-10-24 | Proteus Digital Health, Inc. | Container with electronically controlled interlock |
| US10084880B2 (en) | 2013-11-04 | 2018-09-25 | Proteus Digital Health, Inc. | Social media networking based on physiologic information |
| EP3068397A1 (en) | 2013-11-13 | 2016-09-21 | Euro-Celtique S.A. | Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome |
| US20160256451A1 (en) * | 2015-03-06 | 2016-09-08 | Develco Pharma Schweiz Ag | Dosage of naloxone |
| WO2016193456A2 (en) * | 2015-06-03 | 2016-12-08 | Develco Pharma Schweiz Ag | Opioid receptor antagonist for use in treating patients with severe constipation |
| US11051543B2 (en) | 2015-07-21 | 2021-07-06 | Otsuka Pharmaceutical Co. Ltd. | Alginate on adhesive bilayer laminate film |
| EP3448365A4 (en) * | 2016-04-25 | 2019-12-25 | Gelesis, LLC. | METHOD FOR TREATING CONSTRUCTION |
| WO2018018034A1 (en) | 2016-07-22 | 2018-01-25 | Proteus Digital Health, Inc. | Electromagnetic sensing and detection of ingestible event markers |
| JP2019535377A (ja) | 2016-10-26 | 2019-12-12 | プロテウス デジタル ヘルス, インコーポレイテッド | 摂取可能なイベントマーカを有するカプセルの製造方法 |
| MX2021013488A (es) * | 2019-05-07 | 2021-12-10 | Bausch Health Ireland Ltd | Formulaciones liquidas de dosis oral de metilnaltrexona. |
| CN115040512B (zh) * | 2022-07-28 | 2023-06-20 | 苏州中化药品工业有限公司 | 一种药物组合物及其制备方法 |
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| US4176186A (en) * | 1978-07-28 | 1979-11-27 | Boehringer Ingelheim Gmbh | Quaternary derivatives of noroxymorphone which relieve intestinal immobility |
| JPS5535031A (en) * | 1978-09-04 | 1980-03-11 | Shin Etsu Chem Co Ltd | Enteric coating composition |
| US4311833A (en) * | 1979-03-06 | 1982-01-19 | Daicel Chemical Industries Ltd. | Process for preparing ethylcarboxymethylcellulose |
| US4322426A (en) * | 1980-04-28 | 1982-03-30 | E. I. Du Pont De Nemours And Company | 17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists |
| US4377568A (en) * | 1981-08-12 | 1983-03-22 | Merck Sharp & Dohme (I.A.) Corp. | Preparation of aqueous alcoholic dispersions of pH sensitive polymers and plasticizing agents and a method of enteric coating dosage forms using same |
| DK150008C (da) * | 1981-11-20 | 1987-05-25 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat |
| US4987136A (en) * | 1982-03-16 | 1991-01-22 | The Rockefeller University | Method for controlling gastrointestinal dysmotility |
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| EP0143949B1 (en) * | 1983-11-01 | 1988-10-12 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Pharmaceutical composition containing urokinase |
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| JPS6229515A (ja) * | 1985-07-30 | 1987-02-07 | Shinjiro Tsuji | 硬カプセル剤のフイルムコ−テイング方法 |
| US4861781A (en) * | 1986-03-07 | 1989-08-29 | The University Of Chicago | Quaternary derivatives of noroxymorphone which relieve nausea and emesis |
| US4719215A (en) * | 1986-03-07 | 1988-01-12 | University Of Chicago | Quaternary derivatives of noroxymorphone which relieve nausea and emesis |
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| US4888346A (en) * | 1986-10-07 | 1989-12-19 | Bernard Bihari | Method for the treatment of persons infected with HTLV-III (AIDS) virus |
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| US6274591B1 (en) * | 1997-11-03 | 2001-08-14 | Joseph F. Foss | Use of methylnaltrexone and related compounds |
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| US6194382B1 (en) * | 1999-03-03 | 2001-02-27 | Albert Einstein College Of Medicine Of Yeshiva University | Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists |
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| EP1404323B1 (en) * | 2001-06-05 | 2009-10-28 | The University of Chicago | Use of methylnaltrexone to treat immune suppression |
| PT2939696E (pt) * | 2001-10-18 | 2016-06-17 | Nektar Therapeutics | Conjugados poliméricos de antagonistas de opióides |
| US20030191147A1 (en) * | 2002-04-09 | 2003-10-09 | Barry Sherman | Opioid antagonist compositions and dosage forms |
| US6986901B2 (en) * | 2002-07-15 | 2006-01-17 | Warner-Lambert Company Llc | Gastrointestinal compositions |
| BRPI0409133B8 (pt) * | 2003-04-08 | 2021-05-25 | Progenics Pharm Inc | preparações farmacêuticas estavéis compreendendo metilnaltrexona |
| EP1617846A1 (en) * | 2003-04-08 | 2006-01-25 | Progenics Pharmaceuticals, Inc. | The use of peripheral opiois antagonists, especially methylnaltrexone to treat irritable bowel syndrome |
| US7066888B2 (en) * | 2003-10-29 | 2006-06-27 | Allez Physionix Ltd | Method and apparatus for determining an ultrasound fluid flow centerline |
| EP1845989A1 (en) * | 2005-01-20 | 2007-10-24 | Progenics Pharmaceuticals, Inc. | Use of methylnaltrexone and related compounds to treat post-operative gastrointestinal dysfunction |
| AR057325A1 (es) * | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| AR057035A1 (es) * | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
-
2004
- 2004-04-08 RU RU2005134364/14A patent/RU2005134364A/ru not_active Application Discontinuation
- 2004-04-08 MX MXPA05010821A patent/MXPA05010821A/es unknown
- 2004-04-08 AU AU2004229464A patent/AU2004229464A1/en not_active Abandoned
- 2004-04-08 EP EP04759350A patent/EP1638607A1/en not_active Withdrawn
- 2004-04-08 WO PCT/US2004/010998 patent/WO2004091665A1/en not_active Ceased
- 2004-04-08 JP JP2006509866A patent/JP2006522819A/ja active Pending
- 2004-04-08 BR BRPI0409125-6A patent/BRPI0409125A/pt not_active IP Right Cessation
- 2004-04-08 US US10/821,809 patent/US20040259899A1/en not_active Abandoned
- 2004-04-08 CA CA002521420A patent/CA2521420A1/en not_active Abandoned
- 2004-04-08 CN CNA2004800091912A patent/CN1767855A/zh active Pending
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