JP2006520397A5 - - Google Patents
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- Publication number
- JP2006520397A5 JP2006520397A5 JP2006507956A JP2006507956A JP2006520397A5 JP 2006520397 A5 JP2006520397 A5 JP 2006520397A5 JP 2006507956 A JP2006507956 A JP 2006507956A JP 2006507956 A JP2006507956 A JP 2006507956A JP 2006520397 A5 JP2006520397 A5 JP 2006520397A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- heterocycle
- nhc
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000000623 heterocyclic group Chemical group 0.000 claims 11
- 229910052757 nitrogen Inorganic materials 0.000 claims 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 6
- 125000003107 substituted aryl group Chemical group 0.000 claims 5
- 125000005346 substituted cycloalkyl group Chemical group 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 4
- 125000005017 substituted alkenyl group Chemical group 0.000 claims 4
- 125000005415 substituted alkoxy group Chemical group 0.000 claims 4
- 125000000547 substituted alkyl group Chemical group 0.000 claims 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- 125000000392 cycloalkenyl group Chemical group 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 239000001301 oxygen Substances 0.000 claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 125000004426 substituted alkynyl group Chemical group 0.000 claims 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 150000002989 phenols Chemical class 0.000 claims 2
- 125000000304 alkynyl group Chemical group 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45507303P | 2003-03-14 | 2003-03-14 | |
| US46769003P | 2003-05-02 | 2003-05-02 | |
| US53634304P | 2004-01-14 | 2004-01-14 | |
| PCT/SE2004/000351 WO2004081008A1 (en) | 2003-03-14 | 2004-03-10 | Novel fused triazolones and the uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006520397A JP2006520397A (ja) | 2006-09-07 |
| JP2006520397A5 true JP2006520397A5 (cg-RX-API-DMAC7.html) | 2007-05-10 |
Family
ID=32995996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507956A Pending JP2006520397A (ja) | 2003-03-14 | 2004-03-10 | 新規融合トリアゾロン類及びその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20070149560A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1613625A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2006520397A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20050119647A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2004220176A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0408256A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2519107A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA05009885A (cg-RX-API-DMAC7.html) |
| NO (1) | NO20054083L (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004081008A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7576085B2 (en) * | 2002-09-23 | 2009-08-18 | Schering Corporation | Imidazopyrazines as cyclin dependent kinase inhibitors |
| JPWO2005063222A1 (ja) * | 2003-12-26 | 2007-07-19 | 協和醗酵工業株式会社 | Ｈｓｐ９０ファミリー蛋白質阻害剤 |
| KR101337045B1 (ko) | 2005-02-16 | 2013-12-05 | 아나코르 파마슈티칼스 인코포레이티드 | 보론함유 소분자 |
| WO2006087557A1 (en) * | 2005-02-18 | 2006-08-24 | Astrazeneca Ab | METHOD FOR DETERMINING RESPONSIVENESS TO CHKl INHIBITORS |
| US20070117804A1 (en) * | 2005-11-10 | 2007-05-24 | Schering Corporation | Imidazopyrazines as protein kinase inhibitors |
| CN102532180B (zh) * | 2005-12-30 | 2016-06-29 | 安纳考尔医药公司 | 含硼的小分子 |
| EP1976536A4 (en) | 2005-12-30 | 2011-03-02 | Anacor Pharmaceuticals Inc | SMALL MOLECULES CONTAINING BORON |
| CA2636043A1 (en) * | 2006-01-23 | 2007-08-02 | Amira Pharmaceuticals, Inc. | Tricyclic inhibitors of 5-lipoxygenase |
| TW200806670A (en) * | 2006-04-25 | 2008-02-01 | Merck & Co Inc | Inhibitors of checkpoint kinases |
| JO3598B1 (ar) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| EP2094276A4 (en) * | 2006-12-20 | 2011-01-05 | Abbott Lab | ANTIVIRAL COMPOUNDS |
| US8012965B2 (en) | 2006-12-29 | 2011-09-06 | Rigel Pharmaceuticals, Inc. | Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| WO2009002955A1 (en) * | 2007-06-27 | 2008-12-31 | Sanofi-Aventis U.S. Llc | Process for the preparation of (2r)-2-[4-(7-bromo-2-quinolyloxy)phenoxy]propanoic acid |
| EP2282742A1 (en) * | 2008-04-09 | 2011-02-16 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| CL2009001152A1 (es) | 2008-05-13 | 2009-10-16 | Array Biopharma Inc | Compuestos derivados de n-(4-(cicloalquilo nitrogenado-1-il)-1h-pirrolo[2,3-b]piridin-3-il)amida, inhibidores de cinasa; proceso de preparacion; composicion farmaceutica; y su uso para el tratamiento de una enfermedad proliferativa. |
| WO2010004319A1 (en) * | 2008-07-07 | 2010-01-14 | Astrazeneca Ab | Combination comprising 6-flu0r0-n- ((1s, 4s) - 4- (6-fluoro-2, 4-di0x0-1- (4'- (piperazin-1- ylmethyl) biphenyl- 3-yl) -1, 2-dihydropyrido [2, 3-d] pyrimidin-3 (4h) - yl) cyclohexyl) imidazo [1,2-a] pyridine -2- carboxamide or a salt |
| JP5858789B2 (ja) | 2009-01-16 | 2016-02-10 | ライジェル ファーマシューティカルズ， インコーポレイテッド | 転移性癌の予防、治療、または管理のための併用療法に用いるためのａｘｌ阻害薬 |
| US8614221B2 (en) | 2009-03-11 | 2013-12-24 | Merck Sharp & Dohme Corp. | Inhibitors of Akt activity |
| JP2012523425A (ja) | 2009-04-07 | 2012-10-04 | インフイニトイ プハルマセウトイカルス インコーポレイテッド | 脂肪酸アミドヒドロラーゼの阻害薬 |
| EP2416660B1 (en) | 2009-04-07 | 2014-07-02 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| RU2569061C2 (ru) | 2010-02-03 | 2015-11-20 | Инфинити Фармасьютикалз, Инк. | Ингибиторы амид-гидролазы жирных кислот |
| WO2014060381A1 (de) | 2012-10-18 | 2014-04-24 | Bayer Cropscience Ag | Heterocyclische verbindungen als schädlingsbekämpfungsmittel |
| JP2016503395A (ja) | 2012-10-31 | 2016-02-04 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 病害生物防除剤としての複素環化合物 |
| KR102164612B1 (ko) * | 2014-04-24 | 2020-10-12 | 동아에스티 주식회사 | 아졸계 화합물 및 이를 포함하는 선택적 안드로겐 수용체 효능제 |
| EP3461480A1 (en) | 2017-09-27 | 2019-04-03 | Onxeo | Combination of a dna damage response cell cycle checkpoint inhibitors and belinostat for treating cancer |
| CN118871438A (zh) | 2022-03-01 | 2024-10-29 | 英矽智能科技知识产权有限公司 | 二酰基甘油激酶(DGK)α抑制剂及其用途 |
| WO2023165528A1 (en) * | 2022-03-01 | 2023-09-07 | Insilico Medicine Ip Limited | Diacylglycerol kinase (dgk) alpha inhibitors and uses thereof |
| US20240199608A1 (en) * | 2022-11-15 | 2024-06-20 | Eli Lilly And Company | Ahr agonists |
| CN119874716B (zh) * | 2025-03-27 | 2025-07-15 | 上海隆盛化工有限公司 | 1-氯-6,8-二氟-7-异丙基苯并呋喃并[2,3-c]吡啶及其合成方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3953457A (en) * | 1972-07-28 | 1976-04-27 | Eli Lilly And Company | Agent for the control of plant-pathogenic organisms |
| US4252806A (en) * | 1979-09-24 | 1981-02-24 | Mead Johnson & Company | Triazoloquinolones |
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2004
- 2004-03-10 US US10/549,053 patent/US20070149560A1/en not_active Abandoned
- 2004-03-10 AU AU2004220176A patent/AU2004220176A1/en not_active Abandoned
- 2004-03-10 KR KR1020057017122A patent/KR20050119647A/ko not_active Withdrawn
- 2004-03-10 WO PCT/SE2004/000351 patent/WO2004081008A1/en not_active Ceased
- 2004-03-10 EP EP04719172A patent/EP1613625A1/en not_active Withdrawn
- 2004-03-10 MX MXPA05009885A patent/MXPA05009885A/es not_active Application Discontinuation
- 2004-03-10 JP JP2006507956A patent/JP2006520397A/ja active Pending
- 2004-03-10 CA CA002519107A patent/CA2519107A1/en not_active Abandoned
- 2004-03-10 BR BRPI0408256-7A patent/BRPI0408256A/pt not_active Application Discontinuation
-
2005
- 2005-09-02 NO NO20054083A patent/NO20054083L/no not_active Application Discontinuation