JP2006516532A5 - - Google Patents
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- Publication number
- JP2006516532A5 JP2006516532A5 JP2004533117A JP2004533117A JP2006516532A5 JP 2006516532 A5 JP2006516532 A5 JP 2006516532A5 JP 2004533117 A JP2004533117 A JP 2004533117A JP 2004533117 A JP2004533117 A JP 2004533117A JP 2006516532 A5 JP2006516532 A5 JP 2006516532A5
- Authority
- JP
- Japan
- Prior art keywords
- chemotherapeutic agent
- adjuvant
- chemotherapy
- agent
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002246 antineoplastic agent Substances 0.000 claims 36
- 229940127089 cytotoxic agent Drugs 0.000 claims 36
- 239000002671 adjuvant Substances 0.000 claims 18
- 238000011226 adjuvant chemotherapy Methods 0.000 claims 8
- 229940123237 Taxane Drugs 0.000 claims 7
- 239000012829 chemotherapy agent Substances 0.000 claims 7
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims 7
- 229940045799 anthracyclines and related substance Drugs 0.000 claims 6
- 238000002512 chemotherapy Methods 0.000 claims 5
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 claims 4
- 238000001802 infusion Methods 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 3
- -1 diphenyl compound Chemical class 0.000 claims 3
- AOJJSUZBOXZQNB-VTZDEGQISA-N 4'-epidoxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-VTZDEGQISA-N 0.000 claims 2
- HTIJFSOGRVMCQR-UHFFFAOYSA-N Epirubicin Natural products COc1cccc2C(=O)c3c(O)c4CC(O)(CC(OC5CC(N)C(=O)C(C)O5)c4c(O)c3C(=O)c12)C(=O)CO HTIJFSOGRVMCQR-UHFFFAOYSA-N 0.000 claims 2
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 2
- 229930012538 Paclitaxel Natural products 0.000 claims 2
- 235000010290 biphenyl Nutrition 0.000 claims 2
- 239000004305 biphenyl Substances 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 claims 2
- 229960004679 doxorubicin Drugs 0.000 claims 2
- 229960001904 epirubicin Drugs 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 229960001592 paclitaxel Drugs 0.000 claims 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 claims 2
- 229940063683 taxotere Drugs 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
- 208000005726 Inflammatory Breast Neoplasms Diseases 0.000 claims 1
- 206010021980 Inflammatory carcinoma of the breast Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 125000006267 biphenyl group Chemical group 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 229960001340 histamine Drugs 0.000 claims 1
- 201000004653 inflammatory breast carcinoma Diseases 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
- 125000002456 taxol group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40724202P | 2002-09-03 | 2002-09-03 | |
| PCT/CA2003/001335 WO2004022163A1 (en) | 2002-09-03 | 2003-09-02 | Neoadjuvant treatment of breast cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006516532A JP2006516532A (ja) | 2006-07-06 |
| JP2006516532A5 true JP2006516532A5 (https=) | 2006-08-17 |
Family
ID=31978443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004533117A Pending JP2006516532A (ja) | 2002-09-03 | 2003-09-02 | 乳癌の新補助的処置 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20060160755A1 (https=) |
| EP (1) | EP1545709B1 (https=) |
| JP (1) | JP2006516532A (https=) |
| KR (1) | KR20060039387A (https=) |
| AT (1) | ATE378089T1 (https=) |
| AU (1) | AU2003269621A1 (https=) |
| CA (1) | CA2497246A1 (https=) |
| DE (1) | DE60317537T8 (https=) |
| WO (1) | WO2004022163A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201121924D0 (en) * | 2011-12-20 | 2012-02-01 | Fahy Gurteen Labs Ltd | Detection of breast cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5798339A (en) * | 1990-12-17 | 1998-08-25 | University Of Manitoba | Treatment method for cancer |
| US5618846A (en) * | 1990-12-17 | 1997-04-08 | University Of Manitoba | Treatment method for cancer |
| US5616846A (en) * | 1994-10-27 | 1997-04-01 | Kwasnik; Joseph W. | Method and apparatus for current regulation and temperature compensation |
| PL369792A1 (en) * | 2001-11-01 | 2005-05-02 | Ym Biosciences, Inc. | Use of n,n-diethyl-2-[-4-(phenylmethyl)-phenoxy]ethanamine monohydrochloride (dppe) in cancer therapy |
| US20050119263A1 (en) * | 2001-11-09 | 2005-06-02 | Vincent Mark D. | Treatment of breast cancer |
-
2003
- 2003-09-02 AU AU2003269621A patent/AU2003269621A1/en not_active Abandoned
- 2003-09-02 WO PCT/CA2003/001335 patent/WO2004022163A1/en not_active Ceased
- 2003-09-02 AT AT03750185T patent/ATE378089T1/de not_active IP Right Cessation
- 2003-09-02 DE DE60317537T patent/DE60317537T8/de active Active
- 2003-09-02 JP JP2004533117A patent/JP2006516532A/ja active Pending
- 2003-09-02 KR KR1020057003704A patent/KR20060039387A/ko not_active Ceased
- 2003-09-02 US US10/526,535 patent/US20060160755A1/en not_active Abandoned
- 2003-09-02 CA CA002497246A patent/CA2497246A1/en not_active Abandoned
- 2003-09-02 EP EP03750185A patent/EP1545709B1/en not_active Expired - Lifetime
-
2008
- 2008-08-26 US US12/198,320 patent/US20080318880A1/en not_active Abandoned
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