JP2006514683A - ヒトzvenアンタゴニストの使用 - Google Patents

ヒトzvenアンタゴニストの使用 Download PDF

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Publication number
JP2006514683A
JP2006514683A JP2005501095A JP2005501095A JP2006514683A JP 2006514683 A JP2006514683 A JP 2006514683A JP 2005501095 A JP2005501095 A JP 2005501095A JP 2005501095 A JP2005501095 A JP 2005501095A JP 2006514683 A JP2006514683 A JP 2006514683A
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JP
Japan
Prior art keywords
seq
zven1
amino acid
zven2
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2005501095A
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English (en)
Japanese (ja)
Other versions
JP2006514683A5 (enExample
Inventor
ジェイ. トンプソン,ペニー
オー. シェパード,ポウル
Original Assignee
ザイモジェネティクス,インコーポレイティド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザイモジェネティクス,インコーポレイティド filed Critical ザイモジェネティクス,インコーポレイティド
Publication of JP2006514683A publication Critical patent/JP2006514683A/ja
Publication of JP2006514683A5 publication Critical patent/JP2006514683A5/ja
Pending legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
JP2005501095A 2002-10-07 2003-10-07 ヒトzvenアンタゴニストの使用 Pending JP2006514683A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US41671802P 2002-10-07 2002-10-07
US41671902P 2002-10-07 2002-10-07
US43411602P 2002-12-16 2002-12-16
US43391802P 2002-12-16 2002-12-16
US50860303P 2003-10-03 2003-10-03
US50861403P 2003-10-03 2003-10-03
PCT/US2003/031562 WO2004032850A2 (en) 2002-10-07 2003-10-07 Uses of human zven antagonists

Publications (2)

Publication Number Publication Date
JP2006514683A true JP2006514683A (ja) 2006-05-11
JP2006514683A5 JP2006514683A5 (enExample) 2006-11-16

Family

ID=32097184

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2005501095A Pending JP2006514683A (ja) 2002-10-07 2003-10-07 ヒトzvenアンタゴニストの使用

Country Status (6)

Country Link
US (16) US7291589B2 (enExample)
EP (1) EP1558287A4 (enExample)
JP (1) JP2006514683A (enExample)
AU (2) AU2003279841A1 (enExample)
CA (2) CA2500962A1 (enExample)
WO (2) WO2004031367A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7883872B2 (en) 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
CN1230546C (zh) 1998-10-06 2005-12-07 马克·阿龙·埃马尔法尔布 丝状真菌宿主领域的转化系统
US6485938B1 (en) * 1999-11-16 2002-11-26 Zymogenetics, Inc. Nucleic acid molecules that encodes human Zven1
US20040235732A1 (en) * 2000-11-03 2004-11-25 Qun-Yong Zhou Method for modulating angiogenesis using prokineticin receptor antagonists
EP1572099A4 (en) 2002-10-04 2007-01-03 Univ California SCREENING AND THERAPEUTIC METHODS RELATED TO THE NEUROGENESIS
AU2003279841A1 (en) * 2002-10-07 2004-05-04 Zymogenetics, Inc. Uses of human zven antagonists
EP2526960A1 (en) 2003-03-12 2012-11-28 Genentech, Inc. Use of BV8 and/or EG-VEGF to promote hematopoiesis
US7968710B2 (en) 2005-03-24 2011-06-28 Janssen Pharmaceutica Nv Prokineticin 1 receptor antagonists
JP2008537548A (ja) * 2005-03-24 2008-09-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ プロキネチシン1受容体
CA2622575A1 (en) * 2005-09-13 2007-03-22 Zymogenetics, Inc. Prok2 antagonists and methods of use
CN103396398A (zh) 2005-12-29 2013-11-20 詹森药业有限公司 激肽原1受体拮抗剂
EP2505651A3 (en) 2006-12-10 2013-01-09 Dyadic International, Inc. Isolated fungus with reduced protease activity
WO2008121046A1 (en) * 2007-03-29 2008-10-09 Forskarpatent I Syd Ab Improvement of gastric emptying in patients suffering from diabetes mellitus
US20100286021A1 (en) * 2007-09-25 2010-11-11 Qun-Yong Zhou Methods of Modulating Prokineticin 2 for Treatment of Stress Response and Anxiety-Related Disorders
US11650213B2 (en) * 2015-03-30 2023-05-16 Entvantage Diagnostics, Inc. Devices and assays for diagnosis of viral and bacterial infections

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998046620A1 (en) * 1997-04-17 1998-10-22 Millennium Pharmaceuticals, Inc. A novel human g-protein coupled receptor
WO2002036625A2 (en) * 2000-11-03 2002-05-10 The Regents Of The University Of California Prokineticin polypeptides, related compositions and methods

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4756479A (en) * 1987-04-06 1988-07-12 Lazenby Iii George I Flush hydrant
US5294630A (en) 1992-07-07 1994-03-15 Eli Lilly And Company Treatment of inflammatory bowel disease
US6042821A (en) * 1995-11-21 2000-03-28 Smithkline Beecham Corporation Method of treating sepsis with chemokines
JP2001512013A (ja) 1997-08-01 2001-08-21 ジェンセット 前立腺に発現される分泌タンパク質の5’est
IL139686A0 (en) 1998-06-02 2002-02-10 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7264801B2 (en) 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
US20020172678A1 (en) * 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
US6284725B1 (en) * 1998-10-08 2001-09-04 Bionebraska, Inc. Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue
AU5151100A (en) * 1999-05-19 2000-12-05 Incyte Genomics, Inc. Extracellular signaling molecules
EP1230362A2 (en) * 1999-11-16 2002-08-14 ZymoGenetics, Inc. Human zven proteins
US6485938B1 (en) * 1999-11-16 2002-11-26 Zymogenetics, Inc. Nucleic acid molecules that encodes human Zven1
WO2001048015A2 (en) * 1999-12-28 2001-07-05 Pharmacia & Upjohn Company G protein-coupled receptors
US7045299B2 (en) 2000-07-18 2006-05-16 Takeda Pharmaceutical Company Limited Physiologically active peptide and use thereof
EP1506971A1 (en) * 2000-11-03 2005-02-16 The Regents of the University of California Prokineticin polypeptides, related compositions and methods
US6671555B2 (en) * 2001-04-27 2003-12-30 Medtronic, Inc. Closed loop neuromodulation for suppression of epileptic activity
AU2002359351A1 (en) 2001-11-02 2003-05-19 Nuvelo, Inc. Methods and materials relating to prokineticin-like polypeptides and polynucleotides
WO2004040000A2 (en) * 2002-09-09 2004-05-13 Nura, Inc G protein coupled receptors and uses thereof
AU2003279841A1 (en) * 2002-10-07 2004-05-04 Zymogenetics, Inc. Uses of human zven antagonists
EP1589033A4 (en) 2003-01-22 2006-04-12 Takeda Pharmaceutical ANTIBODY AND ITS USE
EP2526960A1 (en) 2003-03-12 2012-11-28 Genentech, Inc. Use of BV8 and/or EG-VEGF to promote hematopoiesis
US7115560B2 (en) * 2003-03-25 2006-10-03 The Regents Of The University Of California Methods for modulating gastric secretion using prokineticin receptor antagonists
WO2005037870A1 (ja) 2003-10-22 2005-04-28 Takeda Pharmaceutical Company Limited 抗体およびその用途
CA2622575A1 (en) * 2005-09-13 2007-03-22 Zymogenetics, Inc. Prok2 antagonists and methods of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998046620A1 (en) * 1997-04-17 1998-10-22 Millennium Pharmaceuticals, Inc. A novel human g-protein coupled receptor
WO2002036625A2 (en) * 2000-11-03 2002-05-10 The Regents Of The University Of California Prokineticin polypeptides, related compositions and methods

Also Published As

Publication number Publication date
US20070049526A1 (en) 2007-03-01
US20070078259A1 (en) 2007-04-05
US20070065404A1 (en) 2007-03-22
US20070065403A1 (en) 2007-03-22
AU2003295343A8 (en) 2004-04-23
US7592312B2 (en) 2009-09-22
US20070048258A1 (en) 2007-03-01
EP1558287A2 (en) 2005-08-03
AU2003295343A1 (en) 2004-04-23
US20070053908A1 (en) 2007-03-08
US7629445B2 (en) 2009-12-08
US20040156842A1 (en) 2004-08-12
CA2500772A1 (en) 2004-04-22
EP1558287A4 (en) 2009-07-08
US20090312256A1 (en) 2009-12-17
US7205110B2 (en) 2007-04-17
US20040162238A1 (en) 2004-08-19
WO2004032850A3 (en) 2005-03-17
WO2004032850A2 (en) 2004-04-22
US20090312258A1 (en) 2009-12-17
WO2004031367A2 (en) 2004-04-15
AU2003279841A8 (en) 2004-05-04
US20070092912A1 (en) 2007-04-26
US20070087414A1 (en) 2007-04-19
US20090312257A1 (en) 2009-12-17
US20070048778A1 (en) 2007-03-01
US7291589B2 (en) 2007-11-06
US20070053907A1 (en) 2007-03-08
AU2003279841A1 (en) 2004-05-04
CA2500962A1 (en) 2004-04-15
US7531311B2 (en) 2009-05-12
US20070065405A1 (en) 2007-03-22
WO2004031367A3 (en) 2004-07-22

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