JP2006514659A5 - - Google Patents
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- Publication number
- JP2006514659A5 JP2006514659A5 JP2004566776A JP2004566776A JP2006514659A5 JP 2006514659 A5 JP2006514659 A5 JP 2006514659A5 JP 2004566776 A JP2004566776 A JP 2004566776A JP 2004566776 A JP2004566776 A JP 2004566776A JP 2006514659 A5 JP2006514659 A5 JP 2006514659A5
- Authority
- JP
- Japan
- Prior art keywords
- leukemia
- ylmethyloxycarbamoyl
- diethylaminomethyl
- naphth
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 208000032839 leukemia Diseases 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 230000001225 therapeutic effect Effects 0.000 claims 3
- MTVFINVKLYDAFU-UHFFFAOYSA-N 4-n-[[6-(diethylaminomethyl)naphthalen-2-yl]methoxy]-1-n-hydroxybenzene-1,4-dicarboxamide Chemical compound C1=CC2=CC(CN(CC)CC)=CC=C2C=C1CONC(=O)C1=CC=C(C(=O)NO)C=C1 MTVFINVKLYDAFU-UHFFFAOYSA-N 0.000 claims 2
- 208000036762 Acute promyelocytic leukaemia Diseases 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 208000031637 Erythroblastic Acute Leukemia Diseases 0.000 claims 2
- 208000036566 Erythroleukaemia Diseases 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 206010029260 Neuroblastoma Diseases 0.000 claims 2
- 206010039491 Sarcoma Diseases 0.000 claims 2
- 208000021841 acute erythroid leukemia Diseases 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 229940041181 antineoplastic drug Drugs 0.000 claims 2
- VDEUYMSGMPQMIK-UHFFFAOYSA-N benzhydroxamic acid Chemical compound ONC(=O)C1=CC=CC=C1 VDEUYMSGMPQMIK-UHFFFAOYSA-N 0.000 claims 2
- 208000029742 colonic neoplasm Diseases 0.000 claims 2
- 125000006264 diethylaminomethyl group Chemical group [H]C([H])([H])C([H])([H])N(C([H])([H])*)C([H])([H])C([H])([H])[H] 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 201000001441 melanoma Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000064A ITMI20030064A1 (it) | 2003-01-17 | 2003-01-17 | Uso dei derivati dell'acido idrossamico per la preparazione |
| PCT/EP2003/014171 WO2004064824A1 (en) | 2003-01-17 | 2003-12-10 | Use of hydroxamic acid derivatives for the preparation of anti-tumour medicaments |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006514659A JP2006514659A (ja) | 2006-05-11 |
| JP2006514659A5 true JP2006514659A5 (https=) | 2007-01-11 |
| JP4495599B2 JP4495599B2 (ja) | 2010-07-07 |
Family
ID=32750476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004566776A Expired - Lifetime JP4495599B2 (ja) | 2003-01-17 | 2003-12-10 | 抗腫瘍薬の調製のためにヒドロキサム酸誘導体を使用する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8227515B2 (https=) |
| EP (1) | EP1583523B1 (https=) |
| JP (1) | JP4495599B2 (https=) |
| AU (1) | AU2003290034A1 (https=) |
| DE (1) | DE60311888T2 (https=) |
| ES (1) | ES2282705T3 (https=) |
| IT (1) | ITMI20030064A1 (https=) |
| WO (1) | WO2004064824A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1392908B1 (it) * | 2008-09-29 | 2012-04-02 | Italfarmaco Spa | Uso degli inibitori delle istone-deacetilasi per la cura di sindromi mieloproliferative philadelphia-negative |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1283637B1 (it) * | 1996-05-14 | 1998-04-23 | Italfarmaco Spa | Composti ad attivita' antinfiammatoria ed immunosoppressiva |
| KR20020070285A (ko) * | 1999-11-23 | 2002-09-05 | 메틸진, 인크. | 히스톤 디아세틸라제의 억제제 |
| JPWO2002074298A1 (ja) * | 2001-03-21 | 2004-07-08 | 小野薬品工業株式会社 | Ｉｌ−６産生阻害剤 |
| SE0101257D0 (sv) * | 2001-04-06 | 2001-04-06 | A & Science Invest Ab | Treatment of whiplash associated disorder |
| ITMI20011733A1 (it) | 2001-08-07 | 2003-02-07 | Italfarmaco Spa | Derivati dell'acido idrossamico inibitori degli enzimi istone deacetilasi, quali nuovi farmaci antiinfiammatori inibenti la sintesi di citoc |
| JPWO2003070691A1 (ja) * | 2002-02-21 | 2005-06-09 | 財団法人大阪産業振興機構 | Ｎ−ヒドロキシカルボキサミド誘導体 |
-
2003
- 2003-01-17 IT IT000064A patent/ITMI20030064A1/it unknown
- 2003-12-10 EP EP03782390A patent/EP1583523B1/en not_active Expired - Lifetime
- 2003-12-10 US US10/542,244 patent/US8227515B2/en not_active Expired - Lifetime
- 2003-12-10 ES ES03782390T patent/ES2282705T3/es not_active Expired - Lifetime
- 2003-12-10 AU AU2003290034A patent/AU2003290034A1/en not_active Abandoned
- 2003-12-10 DE DE60311888T patent/DE60311888T2/de not_active Expired - Lifetime
- 2003-12-10 JP JP2004566776A patent/JP4495599B2/ja not_active Expired - Lifetime
- 2003-12-10 WO PCT/EP2003/014171 patent/WO2004064824A1/en not_active Ceased
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