JP2006514645A5 - - Google Patents

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Publication number
JP2006514645A5
JP2006514645A5 JP2004560488A JP2004560488A JP2006514645A5 JP 2006514645 A5 JP2006514645 A5 JP 2006514645A5 JP 2004560488 A JP2004560488 A JP 2004560488A JP 2004560488 A JP2004560488 A JP 2004560488A JP 2006514645 A5 JP2006514645 A5 JP 2006514645A5
Authority
JP
Japan
Prior art keywords
hydroxy tamoxifen
subject
transdermally
performing mammography
transdermally administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004560488A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006514645A (ja
JP4684655B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2003/015030 external-priority patent/WO2004054558A2/en
Publication of JP2006514645A publication Critical patent/JP2006514645A/ja
Publication of JP2006514645A5 publication Critical patent/JP2006514645A5/ja
Application granted granted Critical
Publication of JP4684655B2 publication Critical patent/JP4684655B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2004560488A 2002-12-18 2003-12-15 4−ヒドロキシタモキシフェンによる乳房密度低下 Expired - Lifetime JP4684655B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43395802P 2002-12-18 2002-12-18
PCT/EP2003/015030 WO2004054558A2 (en) 2002-12-18 2003-12-15 Reduction of breast density with 4-hydroxy tamoxifen

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010279107A Division JP2011052020A (ja) 2002-12-18 2010-12-15 4−ヒドロキシタモキシフェンによる乳房密度低下

Publications (3)

Publication Number Publication Date
JP2006514645A JP2006514645A (ja) 2006-05-11
JP2006514645A5 true JP2006514645A5 (https=) 2007-02-08
JP4684655B2 JP4684655B2 (ja) 2011-05-18

Family

ID=32595254

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2004560488A Expired - Lifetime JP4684655B2 (ja) 2002-12-18 2003-12-15 4−ヒドロキシタモキシフェンによる乳房密度低下
JP2010279107A Pending JP2011052020A (ja) 2002-12-18 2010-12-15 4−ヒドロキシタモキシフェンによる乳房密度低下

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010279107A Pending JP2011052020A (ja) 2002-12-18 2010-12-15 4−ヒドロキシタモキシフェンによる乳房密度低下

Country Status (6)

Country Link
US (1) US7485623B2 (https=)
EP (3) EP2050443B1 (https=)
JP (2) JP4684655B2 (https=)
AU (1) AU2003296757A1 (https=)
DE (1) DE60327363D1 (https=)
WO (1) WO2004054558A2 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005513080A (ja) * 2001-12-20 2005-05-12 フェムファーマ, インコーポレイテッド 薬物の膣送達
WO2004054557A2 (en) * 2002-12-18 2004-07-01 Laboratoires Besins International Treatment of mastalgia with 4-hydroxy tamoxifen
JP2006515026A (ja) * 2003-01-02 2006-05-18 フェムファーマ ホールディング カンパニー, インコーポレイテッド 乳房の疾患および障害の処置のための薬学的調製物
US9173836B2 (en) 2003-01-02 2015-11-03 FemmeParma Holding Company, Inc. Pharmaceutical preparations for treatments of diseases and disorders of the breast
CA2519980C (en) * 2003-04-01 2012-04-10 Laboratoires Besins International Prevention and treatment of breast cancer with 4-hydroxy tamoxifen
US7767717B2 (en) 2003-06-09 2010-08-03 Ascend Therapeutics, Inc. Treatment and prevention of excessive scarring with 4-hydroxy tamoxifen
US7968532B2 (en) * 2003-12-15 2011-06-28 Besins Healthcare Luxembourg Treatment of gynecomastia with 4-hydroxy tamoxifen
CN1946387B (zh) * 2004-03-22 2011-08-31 法国法杏大药厂 4-羟基三苯氧胺在制备治疗和预防良性乳房疾病的药物中的应用
EP1579856A1 (en) * 2004-03-22 2005-09-28 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
US7507769B2 (en) * 2004-03-22 2009-03-24 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP1579857A1 (en) * 2004-03-22 2005-09-28 Laboratoires Besins International Chemically stable compositions of 4-hydroxy tamoxifen
EP1799201B1 (en) * 2004-10-14 2008-11-26 Laboratoires Besins International 4-hydroxy tamoxifen gel formulations
EP1647271A1 (en) * 2004-10-14 2006-04-19 Laboratoires Besins International 4-Hydroxy tamoxifen gel formulations
GB0602739D0 (en) * 2006-02-10 2006-03-22 Ccbr As Breast tissue density measure
US20080153789A1 (en) * 2006-12-26 2008-06-26 Femmepharma Holding Company, Inc. Topical administration of danazol
CN101861142A (zh) * 2007-11-22 2010-10-13 诺沃-诺迪斯克保健股份有限公司 含醛化合物对液体配制因子VII(a)多肽的稳定化
US20110003000A1 (en) * 2009-07-06 2011-01-06 Femmepharma Holding Company, Inc. Transvaginal Delivery of Drugs
WO2015175561A1 (en) * 2014-05-12 2015-11-19 Quest Diagnostics Investments Incorporated Quantitation of tamoxifen and metabolites thereof by mass spectrometry
AU2017312499B2 (en) 2016-08-19 2023-02-02 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration
IL304863B2 (en) 2017-09-11 2025-08-01 Atossa Therapeutics Inc Methods for making and using endoxifen
JP7662204B2 (ja) 2019-07-03 2025-04-15 アトッサ・セラピューティクス・インコーポレイテッド エンドキシフェンの徐放性組成物
WO2023026139A1 (en) * 2021-08-23 2023-03-02 Singh Divya Dhananjay Pharmaceutical composition comprising 4- hydroxytamoxifen for the treatment of mastalgia

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558373B1 (fr) * 1984-01-20 1987-07-03 Mauvais Jarvis Pierre Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee
ATE80152T1 (de) 1987-04-21 1992-09-15 Heumann Pharma Gmbh & Co Stabile loesungsmitteladdukte von z-1-(p-betadimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl) 2-phenylbut-1-en.
US5045553A (en) * 1987-06-24 1991-09-03 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
US5002938A (en) * 1988-03-21 1991-03-26 Bristol-Myers Squibb Company Antifungal gel formulations
DE3836862A1 (de) 1988-10-27 1990-05-03 Schering Ag Mittel zur transdermalen applikation von steroidhormonen
TW218849B (https=) 1991-05-17 1994-01-11 Bristol Myers Squibb Co
JPH0679002A (ja) * 1993-12-14 1994-03-22 Hisamitsu Pharmaceut Co Inc 経皮投与用パッチシステム
US5613958A (en) 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
DE4407742C1 (de) * 1994-03-08 1995-06-22 Hexal Pharma Gmbh Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat
US5720963A (en) 1994-08-26 1998-02-24 Mary Kay Inc. Barrier disruption treatments for structurally deteriorated skin
DE4434165A1 (de) * 1994-09-24 1996-03-28 Cassella Ag Haarfärbemittel
US6083996A (en) * 1997-11-05 2000-07-04 Nexmed Holdings, Inc. Topical compositions for NSAI drug delivery
US6013270A (en) 1998-04-20 2000-01-11 The Procter & Gamble Company Skin care kit
DE10033853A1 (de) 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
PT1317921E (pt) 2001-12-07 2009-11-06 Besins Mfg Belgium Composição farmacêutica sob a forma de gel ou de solução à base de di-hidrotestosterona, seu processo de preparação e suas utilizações
WO2004054557A2 (en) 2002-12-18 2004-07-01 Laboratoires Besins International Treatment of mastalgia with 4-hydroxy tamoxifen
CA2519980C (en) 2003-04-01 2012-04-10 Laboratoires Besins International Prevention and treatment of breast cancer with 4-hydroxy tamoxifen
US7767717B2 (en) 2003-06-09 2010-08-03 Ascend Therapeutics, Inc. Treatment and prevention of excessive scarring with 4-hydroxy tamoxifen
US7968532B2 (en) 2003-12-15 2011-06-28 Besins Healthcare Luxembourg Treatment of gynecomastia with 4-hydroxy tamoxifen
EP1579857A1 (en) 2004-03-22 2005-09-28 Laboratoires Besins International Chemically stable compositions of 4-hydroxy tamoxifen
US7507769B2 (en) 2004-03-22 2009-03-24 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP1647271A1 (en) 2004-10-14 2006-04-19 Laboratoires Besins International 4-Hydroxy tamoxifen gel formulations

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