JP2006514627A5 - - Google Patents
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- Publication number
- JP2006514627A5 JP2006514627A5 JP2004552884A JP2004552884A JP2006514627A5 JP 2006514627 A5 JP2006514627 A5 JP 2006514627A5 JP 2004552884 A JP2004552884 A JP 2004552884A JP 2004552884 A JP2004552884 A JP 2004552884A JP 2006514627 A5 JP2006514627 A5 JP 2006514627A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- hapten
- enzyme
- target
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42637902P | 2002-11-15 | 2002-11-15 | |
| PCT/GB2003/004994 WO2004045642A1 (en) | 2002-11-15 | 2003-11-17 | Use of multi-specific, non-covalent complexes for targeted delivery of therapeutics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514627A JP2006514627A (ja) | 2006-05-11 |
| JP2006514627A5 true JP2006514627A5 (https=) | 2006-09-28 |
Family
ID=32326341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004552884A Pending JP2006514627A (ja) | 2002-11-15 | 2003-11-17 | 治療薬の標的化送達のための多重特異的非共有結合複合体の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040166115A1 (https=) |
| EP (1) | EP1560596A1 (https=) |
| JP (1) | JP2006514627A (https=) |
| AU (1) | AU2003283599C1 (https=) |
| CA (1) | CA2505717A1 (https=) |
| WO (1) | WO2004045642A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7591994B2 (en) | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| KR20060041205A (ko) * | 2003-07-01 | 2006-05-11 | 이뮤노메딕스, 인코오포레이티드 | 양특이성 항체들의 다가 담체들 |
| US20050261170A1 (en) * | 2004-01-22 | 2005-11-24 | Immunomedics, Inc. | Folate conjugates and complexes |
| US20060057062A1 (en) * | 2004-09-10 | 2006-03-16 | Trotter Dinko G | Compositions and methods useful in pretargeted imaging |
| ES2665422T3 (es) | 2005-03-03 | 2018-04-25 | Immunomedics Inc. | Anticuerpos L243 humanizados |
| ES3000111T3 (en) | 2009-02-13 | 2025-02-27 | Immunomedics Inc | Intermediates for preparing conjugates with an intracellularly-cleavable linkage |
| WO2011003780A1 (en) | 2009-07-06 | 2011-01-13 | F. Hoffmann-La Roche Ag | Bi-specific digoxigenin binding antibodies |
| SG10201501803YA (en) | 2010-03-12 | 2015-05-28 | Immunogen Inc | Cd37-binding molecules and immunoconjugates thereof |
| AU2012236210B2 (en) | 2011-04-01 | 2016-02-04 | Immunogen, Inc. | CD37-binding molecules and immunoconjugates thereof |
| EP2870180B1 (en) | 2012-07-04 | 2024-08-28 | F. Hoffmann-La Roche AG | Anti-biotin antibodies and methods of use |
| RU2684595C2 (ru) | 2012-07-04 | 2019-04-09 | Ф.Хоффманн-Ля Рош Аг | Ковалентно связанные конъюгаты антиген-антитело |
| DK2869837T3 (en) | 2012-07-04 | 2016-09-26 | Hoffmann La Roche | Anti-theophylline antibodies and methods of use |
| AU2014368696A1 (en) | 2013-12-20 | 2016-06-02 | F. Hoffmann-La Roche Ag | Humanized anti-Tau(pS422) antibodies and methods of use |
| EP3089758B1 (en) | 2014-01-03 | 2021-01-27 | F.Hoffmann-La Roche Ag | Covalently linked helicar-anti-helicar antibody conjugates and uses thereof |
| CN105899540B (zh) | 2014-01-03 | 2020-02-07 | 豪夫迈·罗氏有限公司 | 双特异性抗-半抗原/抗-血脑屏障受体的抗体、其复合物及它们作为血脑屏障穿梭物的应用 |
| BR112016014945A2 (pt) | 2014-01-03 | 2018-01-23 | F. Hoffmann-La Roche Ag | conjugado, formulação farmacêutica e uso |
| EP3129065A4 (en) | 2014-03-12 | 2018-01-24 | Invictus Oncology Pvt. Ltd. | Targeted drug delivery through affinity based linkers |
| AR100978A1 (es) * | 2014-06-26 | 2016-11-16 | Hoffmann La Roche | LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS |
| EP3302561A4 (en) | 2015-06-08 | 2019-02-06 | Debiopharm International SA | COMBINATIONS OF ANTI-CD37 IMMUNOCONJUGATE AND ANTI-CD20 ANTIBODIES |
| WO2016207245A1 (en) | 2015-06-24 | 2016-12-29 | F. Hoffmann-La Roche Ag | Humanized anti-tau(ps422) antibodies and methods of use |
| KR102766022B1 (ko) | 2015-08-28 | 2025-02-10 | 데비오팜 인터네셔날 에스 에이 | Cd37 의 검출을 위한 항체 및 검정 |
| EP3535297B1 (en) | 2016-11-02 | 2022-08-10 | Debiopharm International, S.A. | Methods for improving anti-cd37 immunoconjugate therapy |
| US12144818B2 (en) | 2018-05-30 | 2024-11-19 | Debiopharm International, S.A. | Method for treating cancer in a human patient by administering an anti-CD37 immunoconjugate using various dosing regimens |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2604092B1 (fr) * | 1986-09-19 | 1990-04-13 | Immunotech Sa | Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo |
| US6962702B2 (en) * | 1998-06-22 | 2005-11-08 | Immunomedics Inc. | Production and use of novel peptide-based agents for use with bi-specific antibodies |
| US7074405B1 (en) * | 1998-06-22 | 2006-07-11 | Immunomedics, Inc. | Use of bi-specific antibodies for pre-targeting diagnosis and therapy |
| ATE499115T1 (de) * | 1998-09-18 | 2011-03-15 | Immunomedics Inc | Antikörper verwiesene enzymprodrugtherapie mit glukuronidase |
-
2003
- 2003-11-17 EP EP03775576A patent/EP1560596A1/en not_active Ceased
- 2003-11-17 US US10/714,391 patent/US20040166115A1/en not_active Abandoned
- 2003-11-17 JP JP2004552884A patent/JP2006514627A/ja active Pending
- 2003-11-17 AU AU2003283599A patent/AU2003283599C1/en not_active Ceased
- 2003-11-17 CA CA002505717A patent/CA2505717A1/en not_active Abandoned
- 2003-11-17 WO PCT/GB2003/004994 patent/WO2004045642A1/en not_active Ceased
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