JP2006514627A5 - - Google Patents
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- Publication number
- JP2006514627A5 JP2006514627A5 JP2004552884A JP2004552884A JP2006514627A5 JP 2006514627 A5 JP2006514627 A5 JP 2006514627A5 JP 2004552884 A JP2004552884 A JP 2004552884A JP 2004552884 A JP2004552884 A JP 2004552884A JP 2006514627 A5 JP2006514627 A5 JP 2006514627A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- hapten
- enzyme
- target
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42637902P | 2002-11-15 | 2002-11-15 | |
| PCT/GB2003/004994 WO2004045642A1 (en) | 2002-11-15 | 2003-11-17 | Use of multi-specific, non-covalent complexes for targeted delivery of therapeutics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514627A JP2006514627A (ja) | 2006-05-11 |
| JP2006514627A5 true JP2006514627A5 (https=) | 2006-09-28 |
Family
ID=32326341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004552884A Pending JP2006514627A (ja) | 2002-11-15 | 2003-11-17 | 治療薬の標的化送達のための多重特異的非共有結合複合体の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040166115A1 (https=) |
| EP (1) | EP1560596A1 (https=) |
| JP (1) | JP2006514627A (https=) |
| AU (1) | AU2003283599C1 (https=) |
| CA (1) | CA2505717A1 (https=) |
| WO (1) | WO2004045642A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7591994B2 (en) | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| KR20060041205A (ko) * | 2003-07-01 | 2006-05-11 | 이뮤노메딕스, 인코오포레이티드 | 양특이성 항체들의 다가 담체들 |
| AU2005207026A1 (en) * | 2004-01-22 | 2005-08-04 | Immunomedics, Inc. | Folate conjugates and complexes |
| US20060057062A1 (en) * | 2004-09-10 | 2006-03-16 | Trotter Dinko G | Compositions and methods useful in pretargeted imaging |
| ES2665422T3 (es) | 2005-03-03 | 2018-04-25 | Immunomedics Inc. | Anticuerpos L243 humanizados |
| EP3912643B8 (en) | 2009-02-13 | 2023-08-23 | Immunomedics, Inc. | Immunoconjugates with an intracellularly-cleavable linkage |
| SG177560A1 (en) | 2009-07-06 | 2012-03-29 | Hoffmann La Roche | Bi-specific digoxigenin binding antibodies |
| SG183542A1 (en) | 2010-03-12 | 2012-10-30 | Immunogen Inc | Cd37-binding molecules and immunoconjugates thereof |
| EP2694105A4 (en) | 2011-04-01 | 2015-04-29 | Immunogen Inc | CD37 BINDING MOLECULES AND IMMUNOCONJUGATES THEREOF |
| EP3138578B1 (en) | 2012-07-04 | 2022-01-12 | F. Hoffmann-La Roche AG | Anti-theophylline antibodies and methods of use |
| JP6247287B2 (ja) | 2012-07-04 | 2017-12-13 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 抗ビオチン抗体および使用方法 |
| ES2604012T3 (es) | 2012-07-04 | 2017-03-02 | F. Hoffmann-La Roche Ag | Conjugados de antígeno-anticuerpo unidos covalentemente |
| HRP20200384T1 (hr) | 2013-12-20 | 2020-06-12 | F. Hoffmann - La Roche Ag | Humanizirana anti-tau(ps422) protutijela i načini uporabe |
| CA2933384A1 (en) | 2014-01-03 | 2015-07-09 | F. Hoffmann-La Roche Ag | Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles |
| MX373856B (es) | 2014-01-03 | 2020-03-25 | Hoffmann La Roche | Conjugados helicoidales-anticuerpo anti-helicoidal unidos covalentemente y usos de los mismos. |
| BR112016014945A2 (pt) | 2014-01-03 | 2018-01-23 | F. Hoffmann-La Roche Ag | conjugado, formulação farmacêutica e uso |
| EP3129065A4 (en) | 2014-03-12 | 2018-01-24 | Invictus Oncology Pvt. Ltd. | Targeted drug delivery through affinity based linkers |
| AR100978A1 (es) * | 2014-06-26 | 2016-11-16 | Hoffmann La Roche | LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS |
| SG10202108116SA (en) | 2015-06-08 | 2021-08-30 | Debiopharm International S A | Anti-cd37 immunoconjugate and anti-cd20 antibody combinations |
| CN107810196B (zh) | 2015-06-24 | 2021-11-05 | 豪夫迈·罗氏有限公司 | 人源化的抗-Tau(pS422)抗体和使用方法 |
| US11104740B2 (en) | 2015-08-28 | 2021-08-31 | Debiopharm International, S.A. | Antibodies and assays for detection of CD37 |
| US11278629B2 (en) | 2016-11-02 | 2022-03-22 | Debiopharm International, S.A. | Methods for improving anti-CD37 immunoconjugate therapy |
| US12144818B2 (en) | 2018-05-30 | 2024-11-19 | Debiopharm International, S.A. | Method for treating cancer in a human patient by administering an anti-CD37 immunoconjugate using various dosing regimens |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2604092B1 (fr) * | 1986-09-19 | 1990-04-13 | Immunotech Sa | Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo |
| WO1999066951A2 (en) * | 1998-06-22 | 1999-12-29 | Immunomedics, Inc. | Use of bi-specific antibodies for pre-targeting diagnosis and therapy |
| US6962702B2 (en) * | 1998-06-22 | 2005-11-08 | Immunomedics Inc. | Production and use of novel peptide-based agents for use with bi-specific antibodies |
| JP4616991B2 (ja) * | 1998-09-18 | 2011-01-19 | イミューノメディクス、インコーポレイテッド | 化学療法剤の標的特異的な毒性を増加させるための方法および組成物 |
-
2003
- 2003-11-17 JP JP2004552884A patent/JP2006514627A/ja active Pending
- 2003-11-17 AU AU2003283599A patent/AU2003283599C1/en not_active Ceased
- 2003-11-17 EP EP03775576A patent/EP1560596A1/en not_active Ceased
- 2003-11-17 WO PCT/GB2003/004994 patent/WO2004045642A1/en not_active Ceased
- 2003-11-17 US US10/714,391 patent/US20040166115A1/en not_active Abandoned
- 2003-11-17 CA CA002505717A patent/CA2505717A1/en not_active Abandoned
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