JP2006514068A - 局所安定化プロスタグランジンｅ化合物剤形 - Google Patents

局所安定化プロスタグランジンｅ化合物剤形 Download PDF

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Publication number
JP2006514068A
JP2006514068A JP2004566647A JP2004566647A JP2006514068A JP 2006514068 A JP2006514068 A JP 2006514068A JP 2004566647 A JP2004566647 A JP 2004566647A JP 2004566647 A JP2004566647 A JP 2004566647A JP 2006514068 A JP2006514068 A JP 2006514068A
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JP
Japan
Prior art keywords
dosage form
prostaglandin
compound
group
solid dosage
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2004566647A
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English (en)
Japanese (ja)
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JP2006514068A5 (US06841574-20050111-C00009.png
Inventor
モー・ワイ，ジヨージフ
フランク，ダニエル・ダブリユ
Original Assignee
ネクスメツド・ホールデイングス・インコーポレイテツド
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Publication of JP2006514068A publication Critical patent/JP2006514068A/ja
Publication of JP2006514068A5 publication Critical patent/JP2006514068A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
JP2004566647A 2003-01-03 2003-12-31 局所安定化プロスタグランジンｅ化合物剤形 Pending JP2006514068A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/336,481 US6841574B2 (en) 2003-01-03 2003-01-03 Topical stabilized prostaglandin E compound dosage forms
PCT/US2003/041658 WO2004062632A1 (en) 2003-01-03 2003-12-31 Topical stabilized prostaglandin e compound dosage forms

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011200752A Division JP5395138B2 (ja) 2003-01-03 2011-09-14 局所安定化プロスタグランジンｅ化合物剤形

Publications (2)

Publication Number Publication Date
JP2006514068A true JP2006514068A (ja) 2006-04-27
JP2006514068A5 JP2006514068A5 (US06841574-20050111-C00009.png) 2007-02-22

Family

ID=32681022

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2004566647A Pending JP2006514068A (ja) 2003-01-03 2003-12-31 局所安定化プロスタグランジンｅ化合物剤形
JP2011200752A Expired - Fee Related JP5395138B2 (ja) 2003-01-03 2011-09-14 局所安定化プロスタグランジンｅ化合物剤形

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011200752A Expired - Fee Related JP5395138B2 (ja) 2003-01-03 2011-09-14 局所安定化プロスタグランジンｅ化合物剤形

Country Status (17)

Country Link
US (1) US6841574B2 (US06841574-20050111-C00009.png)
EP (1) EP1585483B1 (US06841574-20050111-C00009.png)
JP (2) JP2006514068A (US06841574-20050111-C00009.png)
KR (2) KR20050098853A (US06841574-20050111-C00009.png)
CN (1) CN100574763C (US06841574-20050111-C00009.png)
AT (1) ATE468098T1 (US06841574-20050111-C00009.png)
AU (1) AU2003300113B2 (US06841574-20050111-C00009.png)
BR (1) BR0317924A (US06841574-20050111-C00009.png)
CA (1) CA2512015C (US06841574-20050111-C00009.png)
DE (1) DE60332656D1 (US06841574-20050111-C00009.png)
DK (1) DK1585483T3 (US06841574-20050111-C00009.png)
ES (1) ES2343246T3 (US06841574-20050111-C00009.png)
HK (1) HK1090293A1 (US06841574-20050111-C00009.png)
IL (1) IL169425A (US06841574-20050111-C00009.png)
PT (1) PT1585483E (US06841574-20050111-C00009.png)
WO (1) WO2004062632A1 (US06841574-20050111-C00009.png)
ZA (1) ZA200505321B (US06841574-20050111-C00009.png)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009518405A (ja) * 2005-12-06 2009-05-07 モノソル アールエックス リミテッド ライアビリティ カンパニー 活性物質の送達のための局所フィルム組成物
JP2010506831A (ja) * 2006-10-11 2010-03-04 ネクスメツド・ホールデイングス・インコーポレイテツド 安定化されたプロスタグランジンｅ組成物

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US20050004226A1 (en) * 1998-12-10 2005-01-06 Nexmed (Holdings), Inc. Compositions and methods for amelioration of human female sexual dysfunction
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
US20050181030A1 (en) * 2003-01-03 2005-08-18 Mo Y. J. Topical stabilized prostaglandin E compound dosage forms
EP1605928A1 (en) 2003-03-21 2005-12-21 Nexmed Holdings, Inc. Compositions and methods for treatment of premature ejaculation
WO2005051960A2 (en) * 2003-11-22 2005-06-09 Midwest Research Laboratories, Llc Hydrocarbyl aminohydrocarbonoates and aminohydrocarbonol hydrocarbonoates as antimicrobial and antiviral agents
GB0417401D0 (en) * 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
CA2610465A1 (en) * 2005-06-03 2006-12-14 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions comprising prostanoid-receptor agonists and methods of making and using the same
ITMI20051417A1 (it) * 2005-07-22 2007-01-23 Mipharm S P A Formulazione topica in forma di gel contenente come ingredienti attivi ciclovit e lidocaina
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
ES2921527T3 (es) 2009-06-03 2022-08-29 Forsight Vision5 Inc Administración de fármaco en segmento anterior
US8940794B2 (en) 2011-04-07 2015-01-27 Nexmed Holdings, Inc. Methods and compositions for treating Raynaud's disease
RU2740680C2 (ru) 2011-09-14 2021-01-19 Форсайт Вижн5, Инк. Глазное вкладочное устройство и способы
PT2911623T (pt) 2012-10-26 2019-11-21 Forsight Vision5 Inc Sistema oftálmico para libertação prolongada de fármaco no olho
US8900625B2 (en) * 2012-12-15 2014-12-02 Nexmed Holdings, Inc. Antimicrobial compounds and methods of use
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
WO2019142015A1 (es) * 2018-01-18 2019-07-25 Caicedo Pinto, David Felipe Composicion farmaceutica para la disfuncion erectil de administracion transdermica via uretral en gotas

Citations (8)

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Publication number Priority date Publication date Assignee Title
US4594240A (en) * 1982-09-10 1986-06-10 Teikoku Seiyaku Kabushiki Kaisha Sheet-shape adhesive preparation
US5380760A (en) * 1993-11-19 1995-01-10 Minnesota Mining And Manufacturing Company Transdermal prostaglandin composition
US5908853A (en) * 1992-08-21 1999-06-01 Cesar Roberto Dias Nahoum Compositions
WO1999066870A1 (en) * 1998-06-25 1999-12-29 Lavipharm Laboratories, Inc. A device and method for the treatment of erectile dysfunction
US6046244A (en) * 1997-11-05 2000-04-04 Nexmed Holdings, Inc. Topical compositions for prostaglandin E1 delivery
JP2000511944A (ja) * 1998-06-15 2000-09-12 マクロケム・コーポレーシヨン 陰茎勃起機能不全を治療するための組成物および方法
WO2001074279A1 (en) * 2000-04-04 2001-10-11 Nexmed Holdings, Inc. Topical compositions containing prostaglandin e¿1?
JP2001520190A (ja) * 1997-10-20 2001-10-30 アンドロソルーションズ， インコーポレイテッド 女性の性的欲求および性的応答を増強するための方法、組成物、およびキット

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US3883576A (en) * 1971-02-02 1975-05-13 Upjohn Co Prostaglandin E{HD 3 {B analogs
US3826823A (en) * 1972-09-25 1974-07-30 Syntex Inc Stabilized prostaglandin preparations
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
US4136162A (en) * 1974-07-05 1979-01-23 Schering Aktiengesellschaft Medicament carriers in the form of film having active substance incorporated therein
US5017382A (en) * 1979-03-21 1991-05-21 National Research Development Corporation Controlled release compositions (II)
JPS5770816A (en) * 1980-10-17 1982-05-01 Ono Pharmaceut Co Ltd Multilayered film preparation of prostagladin of prolonged action
JPS58134019A (ja) * 1982-02-05 1983-08-10 Ono Pharmaceut Co Ltd プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法
JPS6185315A (ja) * 1984-10-04 1986-04-30 Teikoku Seiyaku Kk シ−ト状製剤
IE59361B1 (en) * 1986-01-24 1994-02-09 Akzo Nv Pharmaceutical preparation for obtaining a highly viscous hydrogel or suspension
US5219885A (en) * 1987-02-16 1993-06-15 Froelich Juergen Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration
SE9501670L (sv) * 1995-05-05 1996-06-10 Perstorp Ab Omläggningsset
US6593369B2 (en) * 1997-10-20 2003-07-15 Vivus, Inc. Methods, compositions, and kits for enhancing female sexual desire and responsiveness
US6323241B1 (en) * 2000-01-10 2001-11-27 Nexmed (Holdings) Inc. Prostaglandin compositions and methods of treatment for male erectile dysfunction
KR100402334B1 (ko) * 2000-06-23 2003-10-22 환인제약 주식회사 알프로스타딜 외용제

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4594240A (en) * 1982-09-10 1986-06-10 Teikoku Seiyaku Kabushiki Kaisha Sheet-shape adhesive preparation
US5908853A (en) * 1992-08-21 1999-06-01 Cesar Roberto Dias Nahoum Compositions
US5380760A (en) * 1993-11-19 1995-01-10 Minnesota Mining And Manufacturing Company Transdermal prostaglandin composition
JP2001520190A (ja) * 1997-10-20 2001-10-30 アンドロソルーションズ， インコーポレイテッド 女性の性的欲求および性的応答を増強するための方法、組成物、およびキット
US6046244A (en) * 1997-11-05 2000-04-04 Nexmed Holdings, Inc. Topical compositions for prostaglandin E1 delivery
JP2002544240A (ja) * 1997-11-05 2002-12-24 ネックスメド ホールディングス インコーポレイテッド プロスタグランジンｅ１運搬用の局所用組成物
JP2000511944A (ja) * 1998-06-15 2000-09-12 マクロケム・コーポレーシヨン 陰茎勃起機能不全を治療するための組成物および方法
WO1999066870A1 (en) * 1998-06-25 1999-12-29 Lavipharm Laboratories, Inc. A device and method for the treatment of erectile dysfunction
WO2001074279A1 (en) * 2000-04-04 2001-10-11 Nexmed Holdings, Inc. Topical compositions containing prostaglandin e¿1?

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009518405A (ja) * 2005-12-06 2009-05-07 モノソル アールエックス リミテッド ライアビリティ カンパニー 活性物質の送達のための局所フィルム組成物
JP2010506831A (ja) * 2006-10-11 2010-03-04 ネクスメツド・ホールデイングス・インコーポレイテツド 安定化されたプロスタグランジンｅ組成物

Also Published As

Publication number Publication date
US20040131664A1 (en) 2004-07-08
CA2512015C (en) 2011-11-08
CN1756532A (zh) 2006-04-05
CN100574763C (zh) 2009-12-30
US6841574B2 (en) 2005-01-11
IL169425A (en) 2010-11-30
PT1585483E (pt) 2010-06-17
DK1585483T3 (da) 2010-07-19
AU2003300113A1 (en) 2004-08-10
CA2512015A1 (en) 2004-07-29
KR101174788B1 (ko) 2012-08-20
ES2343246T3 (es) 2010-07-27
AU2003300113B2 (en) 2010-03-11
EP1585483B1 (en) 2010-05-19
JP2012036196A (ja) 2012-02-23
HK1090293A1 (en) 2006-12-22
DE60332656D1 (de) 2010-07-01
WO2004062632A1 (en) 2004-07-29
ATE468098T1 (de) 2010-06-15
KR20110042138A (ko) 2011-04-22
EP1585483A1 (en) 2005-10-19
EP1585483A4 (en) 2006-04-19
KR20050098853A (ko) 2005-10-12
JP5395138B2 (ja) 2014-01-22
ZA200505321B (en) 2006-04-26
BR0317924A (pt) 2005-11-29

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