JP2006511620A5 - - Google Patents
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- Publication number
- JP2006511620A5 JP2006511620A5 JP2005508486A JP2005508486A JP2006511620A5 JP 2006511620 A5 JP2006511620 A5 JP 2006511620A5 JP 2005508486 A JP2005508486 A JP 2005508486A JP 2005508486 A JP2005508486 A JP 2005508486A JP 2006511620 A5 JP2006511620 A5 JP 2006511620A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- pharmaceutical formulation
- preparation according
- pharmaceutical
- pharmaceutical preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000008194 pharmaceutical composition Substances 0.000 claims 14
- 239000000825 pharmaceutical preparation Substances 0.000 claims 11
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 229950004393 visilizumab Drugs 0.000 claims 4
- 206010009900 Colitis ulcerative Diseases 0.000 claims 3
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims 2
- GLVAUDGFNGKCSF-UHFFFAOYSA-N mercaptopurine Chemical compound S=C1NC=NC2=C1NC=N2 GLVAUDGFNGKCSF-UHFFFAOYSA-N 0.000 claims 2
- KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical compound NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 claims 2
- 229960004963 mesalazine Drugs 0.000 claims 2
- FELGMEQIXOGIFQ-CYBMUJFWSA-N (3r)-9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1h-carbazol-4-one Chemical compound CC1=NC=CN1C[C@@H]1C(=O)C(C=2C(=CC=CC=2)N2C)=C2CC1 FELGMEQIXOGIFQ-CYBMUJFWSA-N 0.000 claims 1
- VHRSUDSXCMQTMA-PJHHCJLFSA-N 6alpha-methylprednisolone Chemical compound C([C@@]12C)=CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C)[C@@](O)(C(=O)CO)CC[C@H]21 VHRSUDSXCMQTMA-PJHHCJLFSA-N 0.000 claims 1
- 229960000890 hydrocortisone Drugs 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 229960001428 mercaptopurine Drugs 0.000 claims 1
- 229960004584 methylprednisolone Drugs 0.000 claims 1
- 229960005343 ondansetron Drugs 0.000 claims 1
- 229960005489 paracetamol Drugs 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43164902P | 2002-12-05 | 2002-12-05 | |
| US45018303P | 2003-02-25 | 2003-02-25 | |
| PCT/US2003/038809 WO2004052397A1 (en) | 2002-12-05 | 2003-12-05 | Methods of treatment of ulcerative colitis with anti-cd3 antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006511620A JP2006511620A (ja) | 2006-04-06 |
| JP2006511620A5 true JP2006511620A5 (https=) | 2007-01-25 |
Family
ID=32511592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005508486A Pending JP2006511620A (ja) | 2002-12-05 | 2003-12-05 | 抗ｃｄ３抗体による潰瘍性大腸炎の処置方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20040253237A1 (https=) |
| EP (1) | EP1567192A4 (https=) |
| JP (1) | JP2006511620A (https=) |
| KR (1) | KR20050091713A (https=) |
| AU (1) | AU2003298015A1 (https=) |
| CA (1) | CA2508264A1 (https=) |
| WO (1) | WO2004052397A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7883703B2 (en) * | 2003-11-14 | 2011-02-08 | The Brigham And Women's Hospital, Inc. | Methods of modulating immunity |
| CA2569509C (en) | 2004-06-03 | 2014-08-12 | Novimmune S.A. | Anti-cd3 antibodies and methods of use thereof |
| WO2007026742A1 (ja) * | 2005-08-30 | 2007-03-08 | Ajinomoto Co., Inc. | 大腸デリバリー型炎症性大腸疾患治療薬 |
| CN101309703A (zh) * | 2005-09-12 | 2008-11-19 | 诺维莫尼公司 | 抗cd3抗体组合物 |
| EP2433650A3 (en) * | 2006-06-06 | 2012-12-19 | Tolerrx Inc. | Administration of anti-CD3 antibodies in the treatment of autoimmune diseases |
| AU2012201443B2 (en) * | 2006-06-06 | 2014-04-03 | Glaxo Group Limited | Administration of anti-CD3 antibodies in the treatment of autoimmune diseases |
| PT3434767T (pt) | 2010-11-30 | 2026-01-23 | Chugai Pharmaceutical Co Ltd | Agente terapêutico indutor de citotoxicidade |
| WO2017077382A1 (en) | 2015-11-06 | 2017-05-11 | Orionis Biosciences Nv | Bi-functional chimeric proteins and uses thereof |
| CN116769054A (zh) | 2016-02-05 | 2023-09-19 | 奥里尼斯生物科学私人有限公司 | 双特异性信号传导剂及其用途 |
| RU2769282C2 (ru) | 2016-06-20 | 2022-03-30 | Кимаб Лимитед | Анти-PD-L1 и IL-2 цитокины |
| WO2018106945A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| CN110573172A (zh) | 2017-02-06 | 2019-12-13 | 奥里尼斯生物科学有限公司 | 靶向的工程化干扰素及其用途 |
| WO2018183929A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| EP3883635A1 (en) | 2018-11-19 | 2021-09-29 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| CN115666704B (zh) | 2019-12-13 | 2025-09-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| CN113005088B (zh) * | 2019-12-19 | 2024-06-04 | 苏州方德门达新药开发有限公司 | 工程改造的t细胞、其制备及应用 |
| EP4493592A1 (en) | 2022-03-14 | 2025-01-22 | LamKap Bio gamma AG | Bispecific gpc3xcd28 and gpc3xcd3 antibodies and their combination for targeted killing of gpc3 positive malignant cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5932214A (en) * | 1994-08-11 | 1999-08-03 | Biogen, Inc. | Treatment for inflammatory bowel disease with VLA-4 blockers |
| US5834597A (en) * | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| DE19905012A1 (de) * | 1999-02-08 | 2000-08-10 | Gsf Forschungszentrum Umwelt | Arzneimittel enthaltend Anti-CD3- und Anti-Fcgamma-R-Antikörper zur begleitenden Behandlung bei Organtransplantationen |
| WO2004009776A2 (en) * | 2002-07-19 | 2004-01-29 | Abbott Biotechnology Ltd. | TREATMENT OF TNFα RELATED DISORDERS |
-
2003
- 2003-12-05 US US10/729,795 patent/US20040253237A1/en not_active Abandoned
- 2003-12-05 KR KR1020057010239A patent/KR20050091713A/ko not_active Withdrawn
- 2003-12-05 WO PCT/US2003/038809 patent/WO2004052397A1/en not_active Ceased
- 2003-12-05 EP EP03796736A patent/EP1567192A4/en not_active Withdrawn
- 2003-12-05 CA CA002508264A patent/CA2508264A1/en not_active Abandoned
- 2003-12-05 AU AU2003298015A patent/AU2003298015A1/en not_active Abandoned
- 2003-12-05 JP JP2005508486A patent/JP2006511620A/ja active Pending
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