JP2006510654A5 - - Google Patents
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- Publication number
- JP2006510654A5 JP2006510654A5 JP2004558236A JP2004558236A JP2006510654A5 JP 2006510654 A5 JP2006510654 A5 JP 2006510654A5 JP 2004558236 A JP2004558236 A JP 2004558236A JP 2004558236 A JP2004558236 A JP 2004558236A JP 2006510654 A5 JP2006510654 A5 JP 2006510654A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical formulation
- formulation according
- kinase inhibitor
- patient
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 102000002574 p38 Mitogen-Activated Protein Kinases Human genes 0.000 claims 7
- 108010068338 p38 Mitogen-Activated Protein Kinases Proteins 0.000 claims 7
- 229940043355 kinase inhibitor Drugs 0.000 claims 6
- 239000003757 phosphotransferase inhibitor Substances 0.000 claims 6
- 101000628954 Homo sapiens Mitogen-activated protein kinase 12 Proteins 0.000 claims 3
- 102100026932 Mitogen-activated protein kinase 12 Human genes 0.000 claims 3
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 3
- 239000003226 mitogen Substances 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- 102000002812 Heat-Shock Proteins Human genes 0.000 claims 2
- 108010004889 Heat-Shock Proteins Proteins 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008103 glucose Substances 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- 102000006303 Chaperonin 60 Human genes 0.000 claims 1
- 108010058432 Chaperonin 60 Proteins 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 208000016261 weight loss Diseases 0.000 claims 1
- 230000004580 weight loss Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43124102P | 2002-12-06 | 2002-12-06 | |
| PCT/US2003/040140 WO2004053107A2 (en) | 2002-12-06 | 2003-12-05 | Methods for treating diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006510654A JP2006510654A (ja) | 2006-03-30 |
| JP2006510654A5 true JP2006510654A5 (enExample) | 2007-02-01 |
Family
ID=32507688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004558236A Pending JP2006510654A (ja) | 2002-12-06 | 2003-12-05 | 糖尿病を処置する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040171659A1 (enExample) |
| EP (1) | EP1583535A4 (enExample) |
| JP (1) | JP2006510654A (enExample) |
| AU (1) | AU2003299652A1 (enExample) |
| CA (1) | CA2511763A1 (enExample) |
| WO (1) | WO2004053107A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7765004B2 (en) * | 2005-04-28 | 2010-07-27 | Cardiac Pacemakers, Inc. | Methods and systems for managing fusion and noise in cardiac pacing response classification |
| WO2007075896A2 (en) * | 2005-12-22 | 2007-07-05 | Kemia, Inc. | Heterocyclic cytokine inhibitors |
| CA2857374A1 (en) * | 2011-09-02 | 2013-03-07 | The Trustees Of Columbia University In The City Of New York | Camkii, ip3r, calcineurin, p38 and mk2/3 inhibitors to treat metabolic disturbances of obesity |
| PT3691620T (pt) | 2017-10-05 | 2022-10-06 | Fulcrum Therapeutics Inc | Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4107288A (en) * | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| US4619652A (en) * | 1982-12-23 | 1986-10-28 | Alza Corporation | Dosage form for use in a body mounted pump |
| US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| JP2000506532A (ja) * | 1996-03-13 | 2000-05-30 | スミスクライン・ビーチャム・コーポレイション | サイトカイン介在疾患の治療にて有用な新規ピリミジン化合物 |
| GB9713726D0 (en) * | 1997-06-30 | 1997-09-03 | Ciba Geigy Ag | Organic compounds |
| PL340412A1 (en) * | 1997-10-20 | 2001-01-29 | Hoffmann La Roche | Bicyclic kinase inhibitors |
| US6589954B1 (en) * | 1998-05-22 | 2003-07-08 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
| US6599710B1 (en) * | 1999-03-10 | 2003-07-29 | The General Hospital Corporation | Treatment of autoimmune disease |
| AU772295B2 (en) * | 1999-05-21 | 2004-04-22 | Scios Inc. | Indole-type derivatives as inhibitors of p38 kinase |
-
2003
- 2003-12-05 EP EP03799936A patent/EP1583535A4/en not_active Withdrawn
- 2003-12-05 AU AU2003299652A patent/AU2003299652A1/en not_active Abandoned
- 2003-12-05 CA CA002511763A patent/CA2511763A1/en not_active Abandoned
- 2003-12-05 JP JP2004558236A patent/JP2006510654A/ja active Pending
- 2003-12-05 US US10/728,665 patent/US20040171659A1/en not_active Abandoned
- 2003-12-05 WO PCT/US2003/040140 patent/WO2004053107A2/en not_active Ceased
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