JP2006508071A5 - - Google Patents
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- Publication number
- JP2006508071A5 JP2006508071A5 JP2004541774A JP2004541774A JP2006508071A5 JP 2006508071 A5 JP2006508071 A5 JP 2006508071A5 JP 2004541774 A JP2004541774 A JP 2004541774A JP 2004541774 A JP2004541774 A JP 2004541774A JP 2006508071 A5 JP2006508071 A5 JP 2006508071A5
- Authority
- JP
- Japan
- Prior art keywords
- day
- pharmaceutical composition
- estradiol
- range
- levonorgestrel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims 50
- 239000008194 pharmaceutical composition Substances 0.000 claims 26
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 claims 25
- 229960005309 estradiol Drugs 0.000 claims 25
- 229960004400 levonorgestrel Drugs 0.000 claims 20
- 239000007933 dermal patch Substances 0.000 claims 2
- 238000002657 hormone replacement therapy Methods 0.000 claims 2
- 230000037317 transdermal delivery Effects 0.000 claims 2
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/259,892 US20040062794A1 (en) | 2002-09-30 | 2002-09-30 | 17Beta- estradiol/levonorgestrel transdermal patch for hormone replacement therapy |
| PCT/US2003/030493 WO2004030675A1 (en) | 2002-09-30 | 2003-09-29 | 17β-ESTRADIOL/LEVONORGESTREL TRANSDERM PATCH FOR HORMONE REPLACEMENT THERAPY |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006508071A JP2006508071A (ja) | 2006-03-09 |
| JP2006508071A5 true JP2006508071A5 (OSRAM) | 2006-11-16 |
Family
ID=32029580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004541774A Pending JP2006508071A (ja) | 2002-09-30 | 2003-09-29 | ホルモン置換療法のための１７β‐エストラジオール／レボノルゲストレル経皮的パッチ |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20040062794A1 (OSRAM) |
| EP (1) | EP1545547A1 (OSRAM) |
| JP (1) | JP2006508071A (OSRAM) |
| CN (1) | CN1684690A (OSRAM) |
| AU (1) | AU2003279000A1 (OSRAM) |
| BR (1) | BR0314959A (OSRAM) |
| CA (1) | CA2495055A1 (OSRAM) |
| IL (1) | IL166678A0 (OSRAM) |
| MX (1) | MXPA05003364A (OSRAM) |
| RU (1) | RU2005113686A (OSRAM) |
| WO (1) | WO2004030675A1 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7889336B2 (en) * | 2008-02-01 | 2011-02-15 | Vladimir Yankov | Optical integrated nanospectrometer |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| WO2018136161A1 (en) * | 2016-12-05 | 2018-07-26 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4292965A (en) * | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
| US4927687A (en) * | 1984-10-01 | 1990-05-22 | Biotek, Inc. | Sustained release transdermal drug delivery composition |
| US5560922A (en) * | 1986-05-30 | 1996-10-01 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process |
| US5023084A (en) * | 1986-12-29 | 1991-06-11 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
| US4788062A (en) * | 1987-02-26 | 1988-11-29 | Alza Corporation | Transdermal administration of progesterone, estradiol esters, and mixtures thereof |
| US4900734A (en) * | 1987-08-27 | 1990-02-13 | Maxson Wayne S | Novel pharmaceutical composition containing estradiol and progesterone for oral administration |
| US5422119A (en) * | 1987-09-24 | 1995-06-06 | Jencap Research Ltd. | Transdermal hormone replacement therapy |
| US5223261A (en) * | 1988-02-26 | 1993-06-29 | Riker Laboratories, Inc. | Transdermal estradiol delivery system |
| KR960704579A (ko) * | 1993-09-29 | 1996-10-09 | 에드워드 엘. 만델 | 옥시부티닌용 모노글리세리드/락테이트 에스테르 투과 촉진제(Monoglyceride/lactate Ester Permeation Enhancer for Oxybutynin) |
| GR1002079B (en) * | 1994-07-26 | 1995-12-05 | Lavipharm A E | System of a special structure and composition for the rapid transdermal administration of oestrogens. |
| US5922349A (en) * | 1995-09-28 | 1999-07-13 | Schering Aktiengesellschaft | Hormone replacement therapy method and hormone dispenser |
| US6551611B2 (en) * | 1995-09-28 | 2003-04-22 | Schering Aktiengesellschaft | Hormone replacement therapy method |
| US6083528A (en) * | 1995-09-28 | 2000-07-04 | Schering Aktiengesellschaft | Hormone replacement therapy method and hormone dispenser |
| US5702720A (en) * | 1995-12-22 | 1997-12-30 | Minnesota Mining And Manufacturing Company | Transdermal device for the delivery of flurbiprofen |
| DE19548332A1 (de) * | 1995-12-22 | 1997-07-10 | Rotta Res Bv | Hormonpflaster |
| IT1283102B1 (it) * | 1996-06-06 | 1998-04-07 | Permatec Nv | Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele |
| US5855920A (en) * | 1996-12-13 | 1999-01-05 | Chein; Edmund Y. M. | Total hormone replacement therapy |
| ATE293960T1 (de) * | 1997-02-28 | 2005-05-15 | Minnesota Mining & Mfg | Transdermale vorrichtung zur verabreichungvon von testosteron |
| US6193996B1 (en) * | 1998-04-02 | 2001-02-27 | 3M Innovative Properties Company | Device for the transdermal delivery of diclofenac |
| US6312715B1 (en) * | 1998-05-01 | 2001-11-06 | 3M Innovative Properties Company | Adhesive microsphere drug delivery composition |
| DE19827732A1 (de) * | 1998-06-22 | 1999-12-23 | Rottapharm Bv | Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie |
| DE69939019D1 (de) * | 1998-07-07 | 2008-08-14 | Transdermal Technologies Inc | Zusammensetzungen für die schnelle und nicht-irritierende transdermale verabreichung von pharmazeutika and verfahren zur formuliering davon und ihren verabreichung |
| US6586000B2 (en) * | 1999-12-16 | 2003-07-01 | Dermatrends, Inc. | Hydroxide-releasing agents as skin permeation enhancers |
-
2002
- 2002-09-30 US US10/259,892 patent/US20040062794A1/en not_active Abandoned
-
2003
- 2003-09-29 MX MXPA05003364A patent/MXPA05003364A/es not_active Application Discontinuation
- 2003-09-29 CN CNA038233819A patent/CN1684690A/zh active Pending
- 2003-09-29 AU AU2003279000A patent/AU2003279000A1/en not_active Abandoned
- 2003-09-29 EP EP03770511A patent/EP1545547A1/en not_active Withdrawn
- 2003-09-29 RU RU2005113686/14A patent/RU2005113686A/ru not_active Application Discontinuation
- 2003-09-29 WO PCT/US2003/030493 patent/WO2004030675A1/en not_active Ceased
- 2003-09-29 CA CA002495055A patent/CA2495055A1/en not_active Abandoned
- 2003-09-29 JP JP2004541774A patent/JP2006508071A/ja active Pending
- 2003-09-29 BR BR0314959-5A patent/BR0314959A/pt not_active IP Right Cessation
-
2005
- 2005-02-03 IL IL16667805A patent/IL166678A0/xx unknown
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