BR0314959A - Emplastro transdérmico de 17beta-estradiol/levonorgestrel para terapia de reposição hormonal - Google Patents
Emplastro transdérmico de 17beta-estradiol/levonorgestrel para terapia de reposição hormonalInfo
- Publication number
- BR0314959A BR0314959A BR0314959-5A BR0314959A BR0314959A BR 0314959 A BR0314959 A BR 0314959A BR 0314959 A BR0314959 A BR 0314959A BR 0314959 A BR0314959 A BR 0314959A
- Authority
- BR
- Brazil
- Prior art keywords
- levonorgestrel
- estradiol
- replacement therapy
- 17beta
- hormone replacement
- Prior art date
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title abstract 3
- 229960005309 estradiol Drugs 0.000 title abstract 3
- 229960004400 levonorgestrel Drugs 0.000 title abstract 3
- 238000002657 hormone replacement therapy Methods 0.000 title abstract 2
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 abstract 3
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229930182833 estradiol Natural products 0.000 abstract 1
- 230000003054 hormonal effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 238000009256 replacement therapy Methods 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/259,892 US20040062794A1 (en) | 2002-09-30 | 2002-09-30 | 17Beta- estradiol/levonorgestrel transdermal patch for hormone replacement therapy |
| PCT/US2003/030493 WO2004030675A1 (en) | 2002-09-30 | 2003-09-29 | 17β-ESTRADIOL/LEVONORGESTREL TRANSDERM PATCH FOR HORMONE REPLACEMENT THERAPY |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0314959A true BR0314959A (pt) | 2005-08-02 |
Family
ID=32029580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0314959-5A BR0314959A (pt) | 2002-09-30 | 2003-09-29 | Emplastro transdérmico de 17beta-estradiol/levonorgestrel para terapia de reposição hormonal |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20040062794A1 (OSRAM) |
| EP (1) | EP1545547A1 (OSRAM) |
| JP (1) | JP2006508071A (OSRAM) |
| CN (1) | CN1684690A (OSRAM) |
| AU (1) | AU2003279000A1 (OSRAM) |
| BR (1) | BR0314959A (OSRAM) |
| CA (1) | CA2495055A1 (OSRAM) |
| IL (1) | IL166678A0 (OSRAM) |
| MX (1) | MXPA05003364A (OSRAM) |
| RU (1) | RU2005113686A (OSRAM) |
| WO (1) | WO2004030675A1 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7889336B2 (en) * | 2008-02-01 | 2011-02-15 | Vladimir Yankov | Optical integrated nanospectrometer |
| CA2856520C (en) | 2011-11-23 | 2021-04-06 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| AU2017394679A1 (en) * | 2016-12-05 | 2019-06-13 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4292965A (en) * | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
| US4927687A (en) * | 1984-10-01 | 1990-05-22 | Biotek, Inc. | Sustained release transdermal drug delivery composition |
| US5560922A (en) * | 1986-05-30 | 1996-10-01 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process |
| US5023084A (en) * | 1986-12-29 | 1991-06-11 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
| US4788062A (en) * | 1987-02-26 | 1988-11-29 | Alza Corporation | Transdermal administration of progesterone, estradiol esters, and mixtures thereof |
| US4900734A (en) * | 1987-08-27 | 1990-02-13 | Maxson Wayne S | Novel pharmaceutical composition containing estradiol and progesterone for oral administration |
| US5422119A (en) * | 1987-09-24 | 1995-06-06 | Jencap Research Ltd. | Transdermal hormone replacement therapy |
| US5223261A (en) * | 1988-02-26 | 1993-06-29 | Riker Laboratories, Inc. | Transdermal estradiol delivery system |
| KR960704578A (ko) * | 1993-09-29 | 1996-10-09 | 에드워드 엘. 만델 | 모노글리세리드/락테이트 에스테르 투과 촉진제(Monoglyceride/Lactate Ester Permeation Enhancer) |
| GR1002079B (en) * | 1994-07-26 | 1995-12-05 | Lavipharm A E | System of a special structure and composition for the rapid transdermal administration of oestrogens. |
| US5922349A (en) * | 1995-09-28 | 1999-07-13 | Schering Aktiengesellschaft | Hormone replacement therapy method and hormone dispenser |
| US6083528A (en) * | 1995-09-28 | 2000-07-04 | Schering Aktiengesellschaft | Hormone replacement therapy method and hormone dispenser |
| US6551611B2 (en) * | 1995-09-28 | 2003-04-22 | Schering Aktiengesellschaft | Hormone replacement therapy method |
| DE19548332A1 (de) * | 1995-12-22 | 1997-07-10 | Rotta Res Bv | Hormonpflaster |
| US5702720A (en) * | 1995-12-22 | 1997-12-30 | Minnesota Mining And Manufacturing Company | Transdermal device for the delivery of flurbiprofen |
| IT1283102B1 (it) * | 1996-06-06 | 1998-04-07 | Permatec Nv | Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele |
| US5855920A (en) * | 1996-12-13 | 1999-01-05 | Chein; Edmund Y. M. | Total hormone replacement therapy |
| US6132760A (en) * | 1997-02-28 | 2000-10-17 | 3M Innovative Properties Company | Transdermal device for the delivery of testosterone |
| US6193996B1 (en) * | 1998-04-02 | 2001-02-27 | 3M Innovative Properties Company | Device for the transdermal delivery of diclofenac |
| US6312715B1 (en) * | 1998-05-01 | 2001-11-06 | 3M Innovative Properties Company | Adhesive microsphere drug delivery composition |
| DE19827732A1 (de) * | 1998-06-22 | 1999-12-23 | Rottapharm Bv | Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie |
| AU4972599A (en) * | 1998-07-07 | 2000-01-24 | Transdermal Technologies, Inc. | Compositions for rapid and non-irritating transdermal delivery of pharmaceutically active agents and methods for formulating such compositions and delivery thereof |
| US6586000B2 (en) * | 1999-12-16 | 2003-07-01 | Dermatrends, Inc. | Hydroxide-releasing agents as skin permeation enhancers |
-
2002
- 2002-09-30 US US10/259,892 patent/US20040062794A1/en not_active Abandoned
-
2003
- 2003-09-29 MX MXPA05003364A patent/MXPA05003364A/es not_active Application Discontinuation
- 2003-09-29 AU AU2003279000A patent/AU2003279000A1/en not_active Abandoned
- 2003-09-29 CN CNA038233819A patent/CN1684690A/zh active Pending
- 2003-09-29 BR BR0314959-5A patent/BR0314959A/pt not_active IP Right Cessation
- 2003-09-29 WO PCT/US2003/030493 patent/WO2004030675A1/en not_active Ceased
- 2003-09-29 JP JP2004541774A patent/JP2006508071A/ja active Pending
- 2003-09-29 CA CA002495055A patent/CA2495055A1/en not_active Abandoned
- 2003-09-29 RU RU2005113686/14A patent/RU2005113686A/ru not_active Application Discontinuation
- 2003-09-29 EP EP03770511A patent/EP1545547A1/en not_active Withdrawn
-
2005
- 2005-02-03 IL IL16667805A patent/IL166678A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2005113686A (ru) | 2006-01-20 |
| IL166678A0 (en) | 2006-01-15 |
| CA2495055A1 (en) | 2004-04-15 |
| WO2004030675A1 (en) | 2004-04-15 |
| AU2003279000A1 (en) | 2004-04-23 |
| US20040062794A1 (en) | 2004-04-01 |
| EP1545547A1 (en) | 2005-06-29 |
| CN1684690A (zh) | 2005-10-19 |
| MXPA05003364A (es) | 2005-10-05 |
| JP2006508071A (ja) | 2006-03-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0836506T3 (da) | Transdermalt plaster til indgivelse af 17-deacetyl norgestimat alene eller i kombination med et østrogen | |
| CN101940790B (zh) | 一种新型促渗剂组合物及其在透皮给药系统中的应用 | |
| EP0641565B1 (en) | Contraceptive and menstrual cycle controlling drug having oncostatic properties | |
| NZ516502A (en) | Administration of non-oral androgenic steroids to women having an elevated level of sex hormone binding globulin (SHBG) | |
| BR0309780A (pt) | Tratamento da hipertensão em mulheres recebendo terapia de reposição hormonal | |
| MA26834A1 (fr) | Nouveau medicament contraceptif et son mode de preparation | |
| PE20040068A1 (es) | Decanoato, undecanoato y dodecanoato de etonogestrel | |
| JP2013514984A5 (OSRAM) | ||
| CA2431645A1 (en) | Methods of treating hormonal deficiencies in women undergoing estrogen replacement therapy | |
| CN1652798A (zh) | 连续抑制硫酸酯酶的孕激素的激素替代疗法 | |
| JP2016505006A (ja) | レボノルゲストレル及びエチニルエストラジオール用の経皮薬物送達システム | |
| AR036970A1 (es) | Composicion farmaceutica androgenica y metodo para el tratamiento de la depresion | |
| BR0314959A (pt) | Emplastro transdérmico de 17beta-estradiol/levonorgestrel para terapia de reposição hormonal | |
| CA2529983A1 (en) | Preoperative treatment of post operative pain | |
| AU703074B2 (en) | Transdermal delivery device containing an estrogen | |
| HUP0101005A2 (hu) | Szteroid aromatáz gátlót tartalmazó gyógyszer emlőrák megelőzésére és/vagy kezelésére | |
| DK1300143T3 (da) | Plaster som indeholder 4-biphenyleddikesyre | |
| BR0006556A (pt) | Composição farmacêutica para uso tópico à base de corticosteróide para tratamento de fimose | |
| JP4965263B2 (ja) | 浸透増強剤を必要としないホルモンの経皮送達 | |
| Toole et al. | Evaluation of irritation and sensitisation of two 50 μg/day oestrogen patches | |
| HRP20090256T1 (en) | Use of estradiolvalerate and dienogest for oral treatment of dysfunctional uterine bleeding in a contraceptive method | |
| Sitruk-Ware | Routes of delivery for progesterone and progestins | |
| RU2005128284A (ru) | Продленные режимы чрескожной контрацепции | |
| RU2004116082A (ru) | Применение (11бета, 17 бета)-11-(1,3-бензодиоксол-5-ил)-17-гидрокси-17-(1-пропинил) эстра-4,9-диен-3-она при лечении большого депрессивного расстройства | |
| Ibarra de Palacios et al. | Comparative study to evaluate skin irritation and adhesion of Estradot® and Climara® in healthy postmenopausal women |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 6A. E 7A. ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2069 DE 31/08/2010. |