RU2005128284A - Продленные режимы чрескожной контрацепции - Google Patents
Продленные режимы чрескожной контрацепции Download PDFInfo
- Publication number
- RU2005128284A RU2005128284A RU2005128284/14A RU2005128284A RU2005128284A RU 2005128284 A RU2005128284 A RU 2005128284A RU 2005128284/14 A RU2005128284/14 A RU 2005128284/14A RU 2005128284 A RU2005128284 A RU 2005128284A RU 2005128284 A RU2005128284 A RU 2005128284A
- Authority
- RU
- Russia
- Prior art keywords
- contraceptive
- therapy
- ethinyl estradiol
- unit
- administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Claims (8)
1. Способ контрацепции, включающей стадии введения женщине, имеющей менструации, цикла контрацептивной терапии, где каждый цикл терапии включает чрескожное введение комбинации этинилэстрадиола и норелгестромина в течение по меньшей мере 42 последовательных дней, где указанный способ обеспечивает улучшенное регулирование кровотечения и улучшенную величину продолжительности удовлетворительного состояния у женщин, имеющих менструации, использующих указанный способ.
2. Способ по п.1, где каждый цикл терапии включает 56 последовательных дня терапии.
3. Способ по п.2, где каждый цикл включает период без введения гормона, последующий за 56 днями непрерывной терапии.
4. Способ по п.3, где период без введения гормона составляет от 4-8 дней.
5. Способ по п.1, где 20 мкг этинилэстрадиола и 150 мкг норелгестромина вводится ежедневно.
6. Контрацептивная терапевтическая единица, предназначенная для введения при продленном контрацептивном режиме, где указанная единица содержит достаточное количество чрескожных пластырей для обеспечения по меньшей мере 42 последовательных дня контрацептивной терапии, где каждый чрескожный пластырь включает соответствующую матрицу и комбинацию этинилэстрадиола и норелгестромина, и где указанный режим обеспечивает улучшенное регулирование кровотечения и улучшенную величину продолжительности удовлетворительного состояния у женщин, имеющих менструации, использующих указанный режим.
7. Единица по п.6, где указанная единица включает 8 чрескожных пластырей.
8. Единица по п.4, где каждый пластырь обеспечивает ежедневное введение 20 мкг этинилэстрадиола и 150 мкг норелгестромина.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/385,597 US20030219471A1 (en) | 2002-03-11 | 2003-03-11 | Extended cycle estrogen and sulfatase inhibiting progestogen contraceptive regimens |
| US10/385,597 | 2003-03-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2005128284A true RU2005128284A (ru) | 2006-02-10 |
Family
ID=32987305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2005128284/14A RU2005128284A (ru) | 2003-03-11 | 2003-07-24 | Продленные режимы чрескожной контрацепции |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20030219471A1 (ru) |
| EP (1) | EP1613293A1 (ru) |
| KR (1) | KR20070006543A (ru) |
| CN (1) | CN1771024A (ru) |
| AU (1) | AU2003252139A1 (ru) |
| BR (1) | BR0318192A (ru) |
| CA (1) | CA2517778A1 (ru) |
| CR (1) | CR8010A (ru) |
| EC (1) | ECSP056009A (ru) |
| MX (1) | MXPA05009656A (ru) |
| RU (1) | RU2005128284A (ru) |
| WO (1) | WO2004080442A1 (ru) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5898032A (en) | 1997-06-23 | 1999-04-27 | Medical College Of Hampton Roads | Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy |
| PT1453521E (pt) | 2001-12-05 | 2013-10-08 | Teva Womens Health Inc | Contracetivos orais para prevenir a gravidez e diminuir a sintomatologia pré-menstrual |
| WO2004098517A2 (en) | 2003-05-02 | 2004-11-18 | Duramed Pharmaceuticals, Inc. | Methods of hormonal treatment utilizing extended cycle contraceptive regimens |
| US7576226B2 (en) * | 2003-06-30 | 2009-08-18 | Richter Gedeon Vegyeszeti Gyar Rt. | Process of making isomers of norelgestromin and methods using the same |
| CA2771944A1 (en) | 2003-07-16 | 2005-01-27 | Teva Women's Health, Inc. | Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration |
| US20070111975A1 (en) | 2004-10-07 | 2007-05-17 | Duramed Pharmaceuticals, Inc. | Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens |
| US20060135496A1 (en) * | 2004-10-07 | 2006-06-22 | Duramed Pharmaceuticals, Inc. | Methods of hormonal treatment utilizing ascending-dose extended cycle regimens |
| SG172654A1 (en) * | 2006-03-02 | 2011-07-28 | Warner Chilcott Co Llc | Extended cycle multiphasic oral contraceptive method |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3545397A (en) * | 1969-03-17 | 1970-12-08 | Dowty Technical Dev Ltd | Air-cushion vehicles and like craft |
| IL48277A (en) * | 1974-10-18 | 1978-03-10 | Schering Ag | Vaginal ring |
| US4292965A (en) * | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
| SE8602666D0 (sv) * | 1986-06-16 | 1986-06-16 | Leo Ab | Intravaginal devices |
| US5188835A (en) * | 1986-06-16 | 1993-02-23 | Kabi Pharmacia Ab | Intravaginal devices |
| US5006342A (en) * | 1986-12-22 | 1991-04-09 | Cygnus Corporation | Resilient transdermal drug delivery device |
| US4906463A (en) * | 1986-12-22 | 1990-03-06 | Cygnus Research Corporation | Transdermal drug-delivery composition |
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5252334A (en) * | 1989-09-08 | 1993-10-12 | Cygnus Therapeutic Systems | Solid matrix system for transdermal drug delivery |
| DE4344463A1 (de) * | 1993-12-22 | 1995-06-29 | Schering Ag | Kombinationsprodukt zur Kontrazeption |
| HU228434B1 (en) * | 1995-06-07 | 2013-03-28 | Ortho Mcneil Pharm Inc | Transdermal medicament for administering 17-deacetyl norgestimate alone or in combination with an estrogen |
| CN1652796A (zh) * | 2002-03-11 | 2005-08-10 | 詹森药业有限公司 | 使用雌激素和抑制硫酸酯酶的孕激素的长周期避孕给药方案 |
-
2003
- 2003-03-11 US US10/385,597 patent/US20030219471A1/en not_active Abandoned
- 2003-07-24 AU AU2003252139A patent/AU2003252139A1/en not_active Abandoned
- 2003-07-24 KR KR1020057016954A patent/KR20070006543A/ko not_active Application Discontinuation
- 2003-07-24 RU RU2005128284/14A patent/RU2005128284A/ru not_active Application Discontinuation
- 2003-07-24 MX MXPA05009656A patent/MXPA05009656A/es unknown
- 2003-07-24 EP EP03816278A patent/EP1613293A1/en not_active Withdrawn
- 2003-07-24 CN CNA038264390A patent/CN1771024A/zh active Pending
- 2003-07-24 WO PCT/US2003/023134 patent/WO2004080442A1/en not_active Application Discontinuation
- 2003-07-24 CA CA002517778A patent/CA2517778A1/en not_active Abandoned
- 2003-07-24 BR BRPI0318192-8A patent/BR0318192A/pt not_active IP Right Cessation
-
2005
- 2005-09-08 EC EC2005006009A patent/ECSP056009A/es unknown
- 2005-09-28 CR CR8010A patent/CR8010A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003252139A1 (en) | 2004-09-30 |
| CR8010A (es) | 2009-01-16 |
| CN1771024A (zh) | 2006-05-10 |
| MXPA05009656A (es) | 2006-03-08 |
| KR20070006543A (ko) | 2007-01-11 |
| CA2517778A1 (en) | 2004-09-23 |
| BR0318192A (pt) | 2006-03-21 |
| ECSP056009A (es) | 2006-07-28 |
| US20030219471A1 (en) | 2003-11-27 |
| EP1613293A1 (en) | 2006-01-11 |
| WO2004080442A1 (en) | 2004-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20080610 |