JP2006507359A - 心循環器疾患の治療のためのグリコーゲンホスホリラーゼ阻害剤の使用 - Google Patents
心循環器疾患の治療のためのグリコーゲンホスホリラーゼ阻害剤の使用 Download PDFInfo
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- JP2006507359A JP2006507359A JP2005501508A JP2005501508A JP2006507359A JP 2006507359 A JP2006507359 A JP 2006507359A JP 2005501508 A JP2005501508 A JP 2005501508A JP 2005501508 A JP2005501508 A JP 2005501508A JP 2006507359 A JP2006507359 A JP 2006507359A
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- alkyl
- phthalic acid
- phenoxy
- hydroxy
- halogen
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- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 2
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- UHFWEDDFLFAJHG-UHFFFAOYSA-N 1-(2-aminoethyl)-2-(hydroxymethyl)pyrrolidine-3,4-diol Chemical compound NCCN1CC(O)C(O)C1CO UHFWEDDFLFAJHG-UHFFFAOYSA-N 0.000 claims description 2
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- SBDAWMSBMQBJRA-UHFFFAOYSA-N 1-benzyl-2-(hydroxymethyl)pyrrolidine-3,4-diol Chemical compound OCC1C(O)C(O)CN1CC1=CC=CC=C1 SBDAWMSBMQBJRA-UHFFFAOYSA-N 0.000 claims description 2
- AORXTDSJOOFVRB-UHFFFAOYSA-N 1-butyl-2-(hydroxymethyl)pyrrolidine-3,4-diol Chemical compound CCCCN1CC(O)C(O)C1CO AORXTDSJOOFVRB-UHFFFAOYSA-N 0.000 claims description 2
- ITBZTMURQMEUAL-UHFFFAOYSA-N 2-(hydroxymethyl)-1-(2,2,2-trifluoroethyl)pyrrolidine-3,4-diol Chemical compound OCC1C(O)C(O)CN1CC(F)(F)F ITBZTMURQMEUAL-UHFFFAOYSA-N 0.000 claims description 2
- PXKLZLSYHLZPMK-UHFFFAOYSA-N 2-(hydroxymethyl)-1-propylpyrrolidine-3,4-diol Chemical compound CCCN1CC(O)C(O)C1CO PXKLZLSYHLZPMK-UHFFFAOYSA-N 0.000 claims description 2
- OQEBIHBLFRADNM-YUPRTTJUSA-N 2-hydroxymethyl-pyrrolidine-3,4-diol Chemical compound OC[C@@H]1NC[C@H](O)[C@H]1O OQEBIHBLFRADNM-YUPRTTJUSA-N 0.000 claims description 2
- FQOGWNRPPJMSEC-UHFFFAOYSA-N 3-(hydroxymethyl)piperidin-4-ol Chemical compound OCC1CNCCC1O FQOGWNRPPJMSEC-UHFFFAOYSA-N 0.000 claims description 2
- ITQKQYKCQXTDMI-UHFFFAOYSA-N 3-chloro-5-(hydroxymethyl)piperidin-4-ol Chemical compound OCC1CNCC(Cl)C1O ITQKQYKCQXTDMI-UHFFFAOYSA-N 0.000 claims description 2
- DQKZUKLPJVJMSG-UHFFFAOYSA-N 3-fluoro-5-(hydroxymethyl)piperidin-4-ol Chemical compound OCC1CNCC(F)C1O DQKZUKLPJVJMSG-UHFFFAOYSA-N 0.000 claims description 2
- DGBUIVDAWBSYNN-UHFFFAOYSA-N 4-(2-benzamidophenoxy)phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC=C1 DGBUIVDAWBSYNN-UHFFFAOYSA-N 0.000 claims description 2
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- KNIRYHSJMHOIJZ-UHFFFAOYSA-N 4-[2-[[2-fluoro-5-(trifluoromethyl)benzoyl]amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC(C(F)(F)F)=CC=C1F KNIRYHSJMHOIJZ-UHFFFAOYSA-N 0.000 claims description 2
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- AFJVJGBEGXWQNS-UHFFFAOYSA-N 4-[2-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(C(F)(F)F)=C1 AFJVJGBEGXWQNS-UHFFFAOYSA-N 0.000 claims description 2
- MKQSGNJOMQDZCH-UHFFFAOYSA-N 4-[4-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC(C=C1)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 MKQSGNJOMQDZCH-UHFFFAOYSA-N 0.000 claims description 2
- BWWJUWJMTJBQPN-UHFFFAOYSA-N 4-[4-[(4-iodobenzoyl)amino]-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC(C(=C1)NC(=O)C=2C=C(C=CC=2)[N+]([O-])=O)=CC=C1NC(=O)C1=CC=C(I)C=C1 BWWJUWJMTJBQPN-UHFFFAOYSA-N 0.000 claims description 2
- UREVCBHMCDVYLI-UHFFFAOYSA-N 4-[4-acetamido-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=CC([N+]([O-])=O)=CC=1C(=O)NC1=CC(NC(=O)C)=CC=C1OC1=CC=C(C(O)=O)C(C(O)=O)=C1 UREVCBHMCDVYLI-UHFFFAOYSA-N 0.000 claims description 2
- GJXZFZQTSAOZSF-UHFFFAOYSA-N 4-[4-amino-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=CC([N+]([O-])=O)=CC=1C(=O)NC1=CC(N)=CC=C1OC1=CC=C(C(O)=O)C(C(O)=O)=C1 GJXZFZQTSAOZSF-UHFFFAOYSA-N 0.000 claims description 2
- UITDURQSKACGOI-UHFFFAOYSA-N 4-[4-benzamido-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC(C(=C1)NC(=O)C=2C=C(C=CC=2)[N+]([O-])=O)=CC=C1NC(=O)C1=CC=CC=C1 UITDURQSKACGOI-UHFFFAOYSA-N 0.000 claims description 2
- OAZBMVAPRVXFSM-UHFFFAOYSA-N 4-[4-bromo-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=C(Br)C=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 OAZBMVAPRVXFSM-UHFFFAOYSA-N 0.000 claims description 2
- JNEHUYVPZOKWNK-UHFFFAOYSA-N 4-[4-cyano-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=C(C#N)C=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 JNEHUYVPZOKWNK-UHFFFAOYSA-N 0.000 claims description 2
- SXQSXGKQUDBDKG-UHFFFAOYSA-N 4-[4-fluoro-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=C(F)C=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 SXQSXGKQUDBDKG-UHFFFAOYSA-N 0.000 claims description 2
- VIXZBRNAXCGCCC-UHFFFAOYSA-N 4-[4-methoxycarbonyl-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=CC([N+]([O-])=O)=CC=1C(=O)NC1=CC(C(=O)OC)=CC=C1OC1=CC=C(C(O)=O)C(C(O)=O)=C1 VIXZBRNAXCGCCC-UHFFFAOYSA-N 0.000 claims description 2
- JSWGGLZASDOWGM-UHFFFAOYSA-N 4-[4-methyl-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=CC([N+]([O-])=O)=CC=1C(=O)NC1=CC(C)=CC=C1OC1=CC=C(C(O)=O)C(C(O)=O)=C1 JSWGGLZASDOWGM-UHFFFAOYSA-N 0.000 claims description 2
- IVZCUPXQGWYXRH-UHFFFAOYSA-N 4-[5-fluoro-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC(F)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 IVZCUPXQGWYXRH-UHFFFAOYSA-N 0.000 claims description 2
- AJYMAGBHSPVRBG-UHFFFAOYSA-N 4-[5-methyl-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=C(C(O)=O)C(C(O)=O)=CC=1OC1=CC(C)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 AJYMAGBHSPVRBG-UHFFFAOYSA-N 0.000 claims description 2
- MCMVVHHPHOTFDO-UHFFFAOYSA-N 4-chloro-5-(hydroxymethyl)piperidin-3-ol Chemical compound OCC1CNCC(O)C1Cl MCMVVHHPHOTFDO-UHFFFAOYSA-N 0.000 claims description 2
- AMRGLJFRLTZTMG-UHFFFAOYSA-N 4-fluoro-5-(hydroxymethyl)piperidin-3-ol Chemical compound OCC1CNCC(O)C1F AMRGLJFRLTZTMG-UHFFFAOYSA-N 0.000 claims description 2
- VFYAZSTYKPFSFL-UHFFFAOYSA-N 4-{2,4-bis[(3-nitrobenzoyl)amino]phenoxy}phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC(C(=C1)NC(=O)C=2C=C(C=CC=2)[N+]([O-])=O)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 VFYAZSTYKPFSFL-UHFFFAOYSA-N 0.000 claims description 2
- MMWSFXGSQAOMQI-UHFFFAOYSA-N 5-(2-hydroxyethyl)piperidine-3,4-diol Chemical compound OCCC1CNCC(O)C1O MMWSFXGSQAOMQI-UHFFFAOYSA-N 0.000 claims description 2
- KTXBXDGOZMHNIC-UHFFFAOYSA-N 5-(chloromethyl)piperidine-3,4-diol Chemical compound OC1CNCC(CCl)C1O KTXBXDGOZMHNIC-UHFFFAOYSA-N 0.000 claims description 2
- BEQPGACEJJJLEA-UHFFFAOYSA-N 5-(fluoromethyl)piperidine-3,4-diol Chemical compound OC1CNCC(CF)C1O BEQPGACEJJJLEA-UHFFFAOYSA-N 0.000 claims description 2
- WIWXVOPKTGFUMA-UHFFFAOYSA-M 5-(hydroxymethyl)-1,1-dimethylpiperidin-1-ium-3,4-diol;chloride Chemical compound [Cl-].C[N+]1(C)CC(O)C(O)C(CO)C1 WIWXVOPKTGFUMA-UHFFFAOYSA-M 0.000 claims description 2
- CYCTZRRPYHKVQQ-UHFFFAOYSA-N 5-(hydroxymethyl)-1-methylpiperidine-3,4-diol Chemical compound CN1CC(O)C(O)C(CO)C1 CYCTZRRPYHKVQQ-UHFFFAOYSA-N 0.000 claims description 2
- XCPUOKRBVCHXNS-UHFFFAOYSA-N 5-(hydroxymethyl)piperidin-3-ol Chemical compound OCC1CNCC(O)C1 XCPUOKRBVCHXNS-UHFFFAOYSA-N 0.000 claims description 2
- UIALTIIMHGHQRO-UHFFFAOYSA-N 5-ethylpiperidine-3,4-diol Chemical compound CCC1CNCC(O)C1O UIALTIIMHGHQRO-UHFFFAOYSA-N 0.000 claims description 2
- SOWLFRYBIBVUNW-UHFFFAOYSA-N 5-phenylpiperidine-3,4-diol Chemical compound OC1C(O)CNCC1C1=CC=CC=C1 SOWLFRYBIBVUNW-UHFFFAOYSA-N 0.000 claims description 2
- XVRLSSYAFOIBQU-UHFFFAOYSA-N 5-propan-2-ylpiperidine-3,4-diol Chemical compound CC(C)C1CNCC(O)C1O XVRLSSYAFOIBQU-UHFFFAOYSA-N 0.000 claims description 2
- KDHNIDSJJULIGE-UHFFFAOYSA-N 5-propylpiperidine-3,4-diol Chemical compound CCCC1CNCC(O)C1O KDHNIDSJJULIGE-UHFFFAOYSA-N 0.000 claims description 2
- ICJDWETZEPFXIX-KEWYIRBNSA-N CC[C@H]1OC(OC)[C@H](O)[C@@H](O)[C@@H]1O Chemical compound CC[C@H]1OC(OC)[C@H](O)[C@@H](O)[C@@H]1O ICJDWETZEPFXIX-KEWYIRBNSA-N 0.000 claims description 2
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 claims description 2
- FCXGEEJWNLHSQW-UHFFFAOYSA-N dimethyl 4-(2-benzamidophenoxy)benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC=C1 FCXGEEJWNLHSQW-UHFFFAOYSA-N 0.000 claims description 2
- FZDIOJAQYNNMDD-UHFFFAOYSA-N dimethyl 4-[2,4-bis[(3-nitrobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC(C(=C1)NC(=O)C=2C=C(C=CC=2)[N+]([O-])=O)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 FZDIOJAQYNNMDD-UHFFFAOYSA-N 0.000 claims description 2
- MUAOHNWPBPJTCX-UHFFFAOYSA-N dimethyl 4-[2-[(2,3-difluorobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(F)=C1F MUAOHNWPBPJTCX-UHFFFAOYSA-N 0.000 claims description 2
- ZFDCKWGKMGHAHU-UHFFFAOYSA-N dimethyl 4-[2-[(2,4-difluorobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=C(F)C=C1F ZFDCKWGKMGHAHU-UHFFFAOYSA-N 0.000 claims description 2
- OVOVTEJWEVOJQA-UHFFFAOYSA-N dimethyl 4-[2-[(2,5-difluorobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC(F)=CC=C1F OVOVTEJWEVOJQA-UHFFFAOYSA-N 0.000 claims description 2
- FOEMSVVLOJVPQA-UHFFFAOYSA-N dimethyl 4-[2-[(2-fluorobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC=C1F FOEMSVVLOJVPQA-UHFFFAOYSA-N 0.000 claims description 2
- OVDUANNCKBGWQN-UHFFFAOYSA-N dimethyl 4-[2-[(3-acetylbenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(C(C)=O)=C1 OVDUANNCKBGWQN-UHFFFAOYSA-N 0.000 claims description 2
- OTGHWRBMKUJNAF-UHFFFAOYSA-N dimethyl 4-[2-[(3-aminobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(N)=C1 OTGHWRBMKUJNAF-UHFFFAOYSA-N 0.000 claims description 2
- NFPQLJCRDAFOPP-UHFFFAOYSA-N dimethyl 4-[2-[(3-bromobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(Br)=C1 NFPQLJCRDAFOPP-UHFFFAOYSA-N 0.000 claims description 2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200201630 | 2002-10-28 | ||
| US10/429,625 US20040082641A1 (en) | 2002-10-28 | 2003-05-05 | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
| US10/429,626 US6960610B2 (en) | 2002-10-28 | 2003-05-05 | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
| PCT/DK2003/000695 WO2004037233A2 (en) | 2002-10-28 | 2003-10-14 | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006507359A true JP2006507359A (ja) | 2006-03-02 |
| JP2006507359A5 JP2006507359A5 (enExample) | 2006-11-30 |
Family
ID=32180137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005501508A Withdrawn JP2006507359A (ja) | 2002-10-28 | 2003-10-14 | 心循環器疾患の治療のためのグリコーゲンホスホリラーゼ阻害剤の使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20050054618A1 (enExample) |
| EP (1) | EP1558245A2 (enExample) |
| JP (1) | JP2006507359A (enExample) |
| AU (1) | AU2003273762A1 (enExample) |
| WO (1) | WO2004037233A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013508366A (ja) * | 2009-10-19 | 2013-03-07 | アミカス セラピューティックス インコーポレイテッド | 中枢神経系の変性障害を予防および／または治療するための新規の組成物 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| CA2758187C (en) * | 2009-04-09 | 2017-03-07 | Robert Boyd | Methods for preventing and/or treating degenerative disorders of the central nervous system |
| JP5645918B2 (ja) | 2009-04-09 | 2014-12-24 | アミカス セラピューティックス インコーポレイテッド | リソソーム蓄積障害の予防および／または治療方法 |
| WO2011049737A1 (en) | 2009-10-19 | 2011-04-28 | Amicus Therapeutics, Inc. | Novel compositions for preventing and/or treating lysosomal storage disorders |
| ES2526675T3 (es) | 2010-07-09 | 2015-01-14 | Pfizer Limited | N-sulfonilbenzamidas como inhibidores de los canales de sodio dependientes de voltaje |
| WO2012004743A1 (en) | 2010-07-09 | 2012-01-12 | Pfizer Limited | Benzenesulfonamides useful as sodium channel inhibitors |
| WO2020023390A1 (en) | 2018-07-25 | 2020-01-30 | Modernatx, Inc. | Mrna based enzyme replacement therapy combined with a pharmacological chaperone for the treatment of lysosomal storage disorders |
| US11458149B1 (en) | 2019-05-31 | 2022-10-04 | Ikena Oncology, Inc. | TEAD inhibitors and uses thereof |
| BR112021024108A2 (pt) | 2019-05-31 | 2022-03-22 | Ikena Oncology Inc | Inibidores de tead e usos dos mesmos |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5338829A (en) * | 1988-04-20 | 1994-08-16 | Trustees Of The University Of Pennsylvania | Peptides derived from human immunodeficiency virus-1 GP160 |
| US5242687A (en) * | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5759551A (en) * | 1993-04-27 | 1998-06-02 | United Biomedical, Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
| US5705388A (en) * | 1994-12-23 | 1998-01-06 | Ribozyme Pharmaceuticals, Inc. | CETP Ribozymes |
| CZ120398A3 (cs) * | 1995-09-08 | 1998-12-16 | Novo Nordisk A/S | Použití 2-alkylpyrrolidinových derivátů pro přípravu léčiva pro léčbu diabetu, 2-alkylpyrrolidiné deriváty |
| US5998463A (en) * | 1998-02-27 | 1999-12-07 | Pfizer Inc | Glycogen phosphorylase inhibitors |
| EP1150674A1 (en) * | 1999-02-12 | 2001-11-07 | Novo Nordisk A/S | Use of pyrrolidine derivatives for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of obesity or appetite regulation |
-
2003
- 2003-10-14 JP JP2005501508A patent/JP2006507359A/ja not_active Withdrawn
- 2003-10-14 EP EP03757718A patent/EP1558245A2/en not_active Withdrawn
- 2003-10-14 WO PCT/DK2003/000695 patent/WO2004037233A2/en not_active Ceased
- 2003-10-14 AU AU2003273762A patent/AU2003273762A1/en not_active Abandoned
-
2004
- 2004-09-17 US US10/943,548 patent/US20050054618A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013508366A (ja) * | 2009-10-19 | 2013-03-07 | アミカス セラピューティックス インコーポレイテッド | 中枢神経系の変性障害を予防および／または治療するための新規の組成物 |
| JP2015157822A (ja) * | 2009-10-19 | 2015-09-03 | アミカス セラピューティックス インコーポレイテッド | 中枢神経系の変性障害を予防および／または治療するための新規の組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004037233A2 (en) | 2004-05-06 |
| AU2003273762A1 (en) | 2004-05-13 |
| EP1558245A2 (en) | 2005-08-03 |
| US20050054618A1 (en) | 2005-03-10 |
| AU2003273762A8 (en) | 2004-05-13 |
| WO2004037233A3 (en) | 2004-07-29 |
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