JP2006506414A - 抗炎症性３−アリールチオ−３−チアゾリル−アルキルアミン - Google Patents
抗炎症性３−アリールチオ−３−チアゾリル−アルキルアミン Download PDFInfo
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- JP2006506414A JP2006506414A JP2004549780A JP2004549780A JP2006506414A JP 2006506414 A JP2006506414 A JP 2006506414A JP 2004549780 A JP2004549780 A JP 2004549780A JP 2004549780 A JP2004549780 A JP 2004549780A JP 2006506414 A JP2006506414 A JP 2006506414A
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Classifications
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
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- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| SE0203304A SE0203304D0 (sv) | 2002-11-07 | 2002-11-07 | Novel Coumpounds |
| PCT/SE2003/001712 WO2004041794A1 (en) | 2002-11-07 | 2003-11-06 | Antiinflammatory 3-arylthio-3-thiazolyl-alkylamines |
Publications (2)
| Publication Number | Publication Date |
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| JP2006506414A true JP2006506414A (ja) | 2006-02-23 |
| JP2006506414A5 JP2006506414A5 (cg-RX-API-DMAC10.html) | 2006-12-21 |
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| EP (1) | EP1562920B1 (cg-RX-API-DMAC10.html) |
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| AT (1) | ATE331711T1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2003278667A1 (cg-RX-API-DMAC10.html) |
| DE (1) | DE60306546T2 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2268441T3 (cg-RX-API-DMAC10.html) |
| SE (1) | SE0203304D0 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2004041794A1 (cg-RX-API-DMAC10.html) |
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| AR035700A1 (es) * | 2001-05-08 | 2004-06-23 | Astrazeneca Ab | Derivados de arilheteroalquilamina, composicion farmaceutica, usos de estos derivados para la fabricacion de medicamentos, metodos de tratamiento, y proceso para la preparacion de estos derivados |
| SI2610258T1 (sl) | 2007-10-19 | 2014-12-31 | Boehringer Ingelheim International Gmbh | Substituirani piperidino-dihidrotienopirimidini |
| ES2551557T3 (es) | 2008-12-19 | 2015-11-19 | Boehringer Ingelheim International Gmbh | Pirimidin-4-carboxamidas cíclicas como antagonistas del receptor CCR2 para el tratamiento de inflamaciones, asma y EPOC |
| PL2513093T3 (pl) | 2009-12-17 | 2015-03-31 | Centrexion Therapeutics Corp | Nowi antagoniści receptora CCR2 i ich zastosowanie |
| WO2011073155A1 (en) | 2009-12-17 | 2011-06-23 | Boehringer Ingelheim International Gmbh | Novel antagonists for ccr2 and uses thereof |
| CA2786245A1 (en) | 2010-01-29 | 2011-08-04 | Boehringer Ingelheim International Gmbh | Substituted naphthyridines and their use as syk kinase inhibitors |
| EP2569295B1 (en) | 2010-05-12 | 2014-11-19 | Boehringer Ingelheim International GmbH | New ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments |
| WO2011141474A1 (en) | 2010-05-12 | 2011-11-17 | Boehringer Ingelheim International Gmbh | Novel ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments |
| EP2571870B1 (en) | 2010-05-17 | 2015-01-21 | Boehringer Ingelheim International GmbH | Ccr2 antagonists and uses thereof |
| US9018212B2 (en) | 2010-05-25 | 2015-04-28 | Boehringer Ingelheim International Gmbh | Pyridazine carboxamides as CCR2 receptor antagonists |
| JP5721242B2 (ja) | 2010-06-01 | 2015-05-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規ｃｃｒ２アンタゴニスト |
| EP2668177B1 (en) | 2011-01-28 | 2014-10-22 | Boehringer Ingelheim International GmbH | Substituted pyridinyl-pyrimidines and their use as medicaments |
| WO2012171863A1 (en) | 2011-06-16 | 2012-12-20 | Boehringer Ingelheim International Gmbh | New selective ccr2 antagonists |
| JP5786258B2 (ja) | 2011-07-15 | 2015-09-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規かつ選択的なｃｃｒ２拮抗薬 |
| PH12014500209A1 (en) | 2011-07-26 | 2014-03-03 | Boehringer Ingelheim Int | Substituted quinolines and their use as medicaments |
| US20130059866A1 (en) | 2011-08-24 | 2013-03-07 | Boehringer Ingelheim International Gmbh | Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma |
| US9096579B2 (en) | 2012-04-20 | 2015-08-04 | Boehringer Ingelheim International Gmbh | Amino-indolyl-substituted imidazolyl-pyrimidines and their use as medicaments |
| ES2738416T3 (es) | 2014-03-19 | 2020-01-22 | Boehringer Ingelheim Int | Inhibidores heteroarílicos de SYK |
| GB201512635D0 (en) | 2015-07-17 | 2015-08-26 | Ucl Business Plc | Uses of therapeutic compounds |
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| US2688638A (en) * | 1951-07-17 | 1954-09-07 | Givaudan Corp | Nu-(beta-phenoxyethyl) haloethylamines |
| US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
| FR2432500A1 (fr) * | 1978-02-24 | 1980-02-29 | Roussel Uclaf | Nouveaux derives de la benzene propanamine et leurs sels, procede de preparation et application a titre de medicaments |
| US4330546A (en) * | 1979-09-14 | 1982-05-18 | John Wyeth & Brother Limited | 3-Aryl-3-aryloxypropylamines |
| DE3138550A1 (de) * | 1981-09-28 | 1983-04-07 | Boehringer Ingelheim KG, 6507 Ingelheim | Substituierte 2-phenyl-2-(pyridyloxy)-ethylamine und isostere verbindungen, verfahren zu ihrer herstellung und verwendung |
| DE3328348A1 (de) * | 1983-08-05 | 1985-02-14 | Degussa Ag, 6000 Frankfurt | Verfahren zur duennschichtchromatographischen trennung von enantiomeren |
| US4902710A (en) * | 1988-12-14 | 1990-02-20 | Eli Lilly And Company | Serotonin and norepinephrine uptake inhibitors |
| GB0004152D0 (en) * | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel compounds |
| GB0004153D0 (en) * | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel use |
| GB0004149D0 (en) * | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel compounds |
| GB0004151D0 (en) * | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel use |
| AR035700A1 (es) * | 2001-05-08 | 2004-06-23 | Astrazeneca Ab | Derivados de arilheteroalquilamina, composicion farmaceutica, usos de estos derivados para la fabricacion de medicamentos, metodos de tratamiento, y proceso para la preparacion de estos derivados |
| SE0102640D0 (sv) * | 2001-07-31 | 2001-07-31 | Astrazeneca Ab | Novel compounds |
| SE0102641D0 (sv) * | 2001-07-31 | 2001-07-31 | Astrazeneca Ab | Novel compounds |
| US7084122B2 (en) * | 2001-11-21 | 2006-08-01 | Erik Larsen | Use of glycosides of mono- and diacyglycerol as anti-inflammatory agents |
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2003
- 2003-11-06 AT AT03770201T patent/ATE331711T1/de not_active IP Right Cessation
- 2003-11-06 EP EP03770201A patent/EP1562920B1/en not_active Expired - Lifetime
- 2003-11-06 JP JP2004549780A patent/JP2006506414A/ja not_active Withdrawn
- 2003-11-06 WO PCT/SE2003/001712 patent/WO2004041794A1/en not_active Ceased
- 2003-11-06 AU AU2003278667A patent/AU2003278667A1/en not_active Abandoned
- 2003-11-06 US US10/534,191 patent/US20060040992A1/en not_active Abandoned
- 2003-11-06 ES ES03770201T patent/ES2268441T3/es not_active Expired - Lifetime
- 2003-11-06 DE DE60306546T patent/DE60306546T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60306546T2 (de) | 2007-07-05 |
| DE60306546D1 (de) | 2006-08-10 |
| EP1562920B1 (en) | 2006-06-28 |
| SE0203304D0 (sv) | 2002-11-07 |
| ES2268441T3 (es) | 2007-03-16 |
| ATE331711T1 (de) | 2006-07-15 |
| AU2003278667A1 (en) | 2004-06-07 |
| EP1562920A1 (en) | 2005-08-17 |
| WO2004041794A8 (en) | 2005-03-10 |
| US20060040992A1 (en) | 2006-02-23 |
| WO2004041794A1 (en) | 2004-05-21 |
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