JP2006505536A5 - - Google Patents
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- Publication number
- JP2006505536A5 JP2006505536A5 JP2004540158A JP2004540158A JP2006505536A5 JP 2006505536 A5 JP2006505536 A5 JP 2006505536A5 JP 2004540158 A JP2004540158 A JP 2004540158A JP 2004540158 A JP2004540158 A JP 2004540158A JP 2006505536 A5 JP2006505536 A5 JP 2006505536A5
- Authority
- JP
- Japan
- Prior art keywords
- human
- protein
- patient
- peptide
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 102000008857 Ferritin Human genes 0.000 claims 2
- 108050000784 Ferritin Proteins 0.000 claims 2
- 239000012503 blood component Substances 0.000 claims 2
- 208000031886 HIV Infections Diseases 0.000 claims 1
- 208000037357 HIV infectious disease Diseases 0.000 claims 1
- 101000799972 Homo sapiens Alpha-2-macroglobulin Proteins 0.000 claims 1
- 101000766306 Homo sapiens Serotransferrin Proteins 0.000 claims 1
- 102000008100 Human Serum Albumin Human genes 0.000 claims 1
- 108091006905 Human Serum Albumin Proteins 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 102000009488 Thyroxine-Binding Proteins Human genes 0.000 claims 1
- 108010048889 Thyroxine-Binding Proteins Proteins 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 102000049437 human A2M Human genes 0.000 claims 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 102000005963 steroid binding proteins Human genes 0.000 claims 1
- 108020003178 steroid binding proteins Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41279702P | 2002-09-24 | 2002-09-24 | |
| US60/412,797 | 2002-09-24 | ||
| PCT/US2003/029815 WO2004029201A2 (en) | 2002-09-24 | 2003-09-23 | Peptide derivative fusion inhibitors of hiv infection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010105068A Division JP2010209097A (ja) | 2002-09-24 | 2010-04-30 | Ｈｉｖ感染のペプチド誘導体融合阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006505536A JP2006505536A (ja) | 2006-02-16 |
| JP2006505536A5 true JP2006505536A5 (https=) | 2006-11-09 |
| JP5385497B2 JP5385497B2 (ja) | 2014-01-08 |
Family
ID=32043189
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004540158A Expired - Lifetime JP5385497B2 (ja) | 2002-09-24 | 2003-09-23 | Ｈｉｖ感染のペプチド誘導体融合阻害剤 |
| JP2010105068A Pending JP2010209097A (ja) | 2002-09-24 | 2010-04-30 | Ｈｉｖ感染のペプチド誘導体融合阻害剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010105068A Pending JP2010209097A (ja) | 2002-09-24 | 2010-04-30 | Ｈｉｖ感染のペプチド誘導体融合阻害剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US7575750B2 (https=) |
| EP (1) | EP1542718B1 (https=) |
| JP (2) | JP5385497B2 (https=) |
| CN (1) | CN1327897C (https=) |
| AP (1) | AP2203A (https=) |
| AU (2) | AU2003275116A1 (https=) |
| BR (1) | BR0314657A (https=) |
| CA (1) | CA2500248C (https=) |
| CR (1) | CR7806A (https=) |
| EA (1) | EA007918B1 (https=) |
| ES (1) | ES2558680T3 (https=) |
| IL (1) | IL167527A (https=) |
| NZ (1) | NZ539539A (https=) |
| WO (1) | WO2004029201A2 (https=) |
| ZA (1) | ZA200503118B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE295370T1 (de) | 2001-05-31 | 2005-05-15 | Conjuchem Inc | Langwirkende fusionspeptid-inhibitoren für hiv- infektion |
| EP1542718B1 (en) * | 2002-09-24 | 2015-11-11 | Dong Xie | Peptide derivative fusion inhibitors of hiv infection |
| CN100455594C (zh) * | 2005-12-14 | 2009-01-28 | 中国人民解放军军事医学科学院生物工程研究所 | 抑制hiv病毒融合的多肽及其用途 |
| CN1793170A (zh) * | 2005-12-14 | 2006-06-28 | 中国人民解放军军事医学科学院生物工程研究所 | 抑制hiv病毒融合的多肽及其用途 |
| CN101384623B (zh) * | 2005-12-22 | 2013-07-24 | 常山凯捷健生物药物研发（河北）有限公司 | 白蛋白与治疗剂的预成型偶联物的制备方法 |
| WO2008144590A2 (en) * | 2007-05-16 | 2008-11-27 | Conjuchem Biotechnologies Inc. | Long lasting modified antifusogenic peptide for preventing hiv infection |
| WO2012022040A1 (zh) * | 2010-08-19 | 2012-02-23 | 清华大学 | Hiv-1病毒膜融合抑制剂及其应用 |
| CN103664701A (zh) * | 2013-11-29 | 2014-03-26 | 成都普康生物科技有限公司 | [2-[2-(Fmoc-氨基)乙氧基]乙氧基]乙酸合成路线 |
| WO2020223906A1 (en) | 2019-05-07 | 2020-11-12 | Frontier Biotechnologies Inc. | Stable albuvirtide compositions |
| WO2022003674A1 (en) * | 2020-06-28 | 2022-01-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Neutrophil-binding peptides |
| CN115025218B (zh) * | 2021-07-30 | 2025-03-28 | 前沿生物药业(南京)股份有限公司 | 联用治疗人类免疫缺陷病毒的活性组合及其应用 |
| WO2024238349A1 (en) * | 2023-05-12 | 2024-11-21 | Frontier Medicines Corporation | Identification and characterization of protein sites |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3719667A (en) * | 1970-08-24 | 1973-03-06 | Lilly Co Eli | Epimerization of 6-acylamido and 6-imido penicillin sulfoxide esters |
| US3840556A (en) | 1971-05-28 | 1974-10-08 | Lilly Co Eli | Penicillin conversion by halogen electrophiles and anti-bacterials derived thereby |
| US3791667A (en) * | 1972-05-04 | 1974-02-12 | H Haviland | Retractable vehicle passenger cushioning system |
| US5612034A (en) * | 1990-10-03 | 1997-03-18 | Redcell, Inc. | Super-globuling for in vivo extended lifetimes |
| AU666853B2 (en) | 1991-04-05 | 1996-02-29 | Genentech Inc. | Platelet aggregation inhibitors having high specificity for GP IIbIIIa |
| AU723537B2 (en) * | 1995-06-07 | 2000-08-31 | Trimeris Inc. | The treatment of HIV and other viral infections using combinatorial therapy |
| US5624902A (en) | 1995-06-07 | 1997-04-29 | Torrey Pines Institute For Molecular Studies | Peptide inhibitors of calmodulin |
| US6268479B1 (en) | 1997-03-12 | 2001-07-31 | The Trustees Of Columbia University In The City Of New York | Intracellular amyloid-beta peptide binding (ERAB) polypeptide |
| US6281331B1 (en) * | 1998-03-23 | 2001-08-28 | Trimeris, Inc. | Methods and compositions for peptide synthesis |
| US6258782B1 (en) * | 1998-05-20 | 2001-07-10 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
| US6656906B1 (en) | 1998-05-20 | 2003-12-02 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
| JP4209086B2 (ja) * | 1999-05-17 | 2009-01-14 | コンジュケム バイオテクノロジーズ インコーポレイテッド | 長期持続性抗新脈管形成ペプチド |
| EP1179012B2 (en) | 1999-05-17 | 2009-07-15 | ConjuChem Biotechnologies Inc. | Long lasting fusion peptide inhibitors of viral infection |
| BR0010750A (pt) * | 1999-05-17 | 2002-02-26 | Conjuchem Inc | Peptìdeos insulinotrópicos de longa duração |
| CA2373680C (en) * | 1999-05-17 | 2008-07-29 | Conjuchem Inc. | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
| US6750008B1 (en) * | 1999-07-09 | 2004-06-15 | Trimeris, Inc. | Methods and compositions for inhibition of membrane fusion-associated events, including HIV transmission |
| CN1172717C (zh) * | 2000-08-18 | 2004-10-27 | 清华大学 | 一种治疗艾滋病的药物及其制备方法 |
| EP1542718B1 (en) * | 2002-09-24 | 2015-11-11 | Dong Xie | Peptide derivative fusion inhibitors of hiv infection |
-
2003
- 2003-09-23 EP EP03759385.2A patent/EP1542718B1/en not_active Expired - Lifetime
- 2003-09-23 NZ NZ539539A patent/NZ539539A/en not_active IP Right Cessation
- 2003-09-23 CN CNB038164345A patent/CN1327897C/zh not_active Expired - Lifetime
- 2003-09-23 BR BR0314657-0A patent/BR0314657A/pt not_active IP Right Cessation
- 2003-09-23 JP JP2004540158A patent/JP5385497B2/ja not_active Expired - Lifetime
- 2003-09-23 US US10/667,966 patent/US7575750B2/en not_active Expired - Lifetime
- 2003-09-23 AP AP2005003291A patent/AP2203A/xx active
- 2003-09-23 ES ES03759385.2T patent/ES2558680T3/es not_active Expired - Lifetime
- 2003-09-23 AU AU2003275116A patent/AU2003275116A1/en not_active Abandoned
- 2003-09-23 CA CA2500248A patent/CA2500248C/en not_active Expired - Lifetime
- 2003-09-23 EA EA200500533A patent/EA007918B1/ru not_active IP Right Cessation
- 2003-09-23 WO PCT/US2003/029815 patent/WO2004029201A2/en not_active Ceased
-
2005
- 2005-03-17 IL IL167527A patent/IL167527A/en active IP Right Grant
- 2005-04-18 ZA ZA200503118A patent/ZA200503118B/en unknown
- 2005-04-22 CR CR7806A patent/CR7806A/es unknown
-
2009
- 2009-09-25 US US12/567,250 patent/US8470527B2/en not_active Expired - Fee Related
-
2010
- 2010-03-04 AU AU2010200823A patent/AU2010200823B2/en not_active Ceased
- 2010-04-30 JP JP2010105068A patent/JP2010209097A/ja active Pending
-
2013
- 2013-06-25 US US13/926,698 patent/US20140187476A1/en not_active Abandoned
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