JP2006503901A5 - - Google Patents

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Publication number
JP2006503901A5
JP2006503901A5 JP2004548325A JP2004548325A JP2006503901A5 JP 2006503901 A5 JP2006503901 A5 JP 2006503901A5 JP 2004548325 A JP2004548325 A JP 2004548325A JP 2004548325 A JP2004548325 A JP 2004548325A JP 2006503901 A5 JP2006503901 A5 JP 2006503901A5
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JP
Japan
Prior art keywords
condition
composition
receptor
disease
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004548325A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006503901A (ja
JP4705783B2 (ja
Filing date
Publication date
Priority claimed from US10/280,085 external-priority patent/US6627602B2/en
Application filed filed Critical
Publication of JP2006503901A publication Critical patent/JP2006503901A/ja
Publication of JP2006503901A5 publication Critical patent/JP2006503901A5/ja
Application granted granted Critical
Publication of JP4705783B2 publication Critical patent/JP4705783B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2004548325A 2002-10-25 2003-10-20 レセプターの脱感作の予防 Expired - Fee Related JP4705783B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/280,085 US6627602B2 (en) 2001-11-13 2002-10-25 Preventing desensitization of receptors
US10/280,085 2002-10-25
PCT/US2003/029134 WO2004039313A2 (en) 2002-10-25 2003-10-20 Preventing desensitization of receptors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010101547A Division JP2010159307A (ja) 2002-10-25 2010-04-26 レセプターの脱感作の予防

Publications (3)

Publication Number Publication Date
JP2006503901A JP2006503901A (ja) 2006-02-02
JP2006503901A5 true JP2006503901A5 (https=) 2006-11-09
JP4705783B2 JP4705783B2 (ja) 2011-06-22

Family

ID=32228743

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2004548325A Expired - Fee Related JP4705783B2 (ja) 2002-10-25 2003-10-20 レセプターの脱感作の予防
JP2010101547A Withdrawn JP2010159307A (ja) 2002-10-25 2010-04-26 レセプターの脱感作の予防

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010101547A Withdrawn JP2010159307A (ja) 2002-10-25 2010-04-26 レセプターの脱感作の予防

Country Status (6)

Country Link
US (3) US6627602B2 (https=)
EP (1) EP1567182A4 (https=)
JP (2) JP4705783B2 (https=)
AU (1) AU2003287006B2 (https=)
CA (1) CA2503624A1 (https=)
WO (1) WO2004039313A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627738B2 (en) * 1995-09-15 2003-09-30 Duke University No-modified hemoglobins and uses therefor
CA2425489C (en) * 2000-10-16 2011-05-17 Duke University Therapeutic use of aerosolized s-nitrosoglutathione in cystic fibrosis
AU2002224466A1 (en) * 2000-10-31 2002-05-15 Duke University Hypotension
US20040110691A1 (en) * 2001-11-13 2004-06-10 Stamler Jonathan S. Thiol reactive agents as a therapeutic modality
US6627602B2 (en) * 2001-11-13 2003-09-30 Duke University Preventing desensitization of receptors
GB0326047D0 (en) * 2003-11-07 2003-12-10 Univ Sheffield Substance
ES2543836T3 (es) * 2004-04-23 2015-08-24 Northern Sydney Local Health District Procedimientos y composiciones para el tratamiento de afecciones miocárdicas
ES2731298T3 (es) 2005-05-27 2019-11-14 Univ North Carolina Chapel Hill Partículas de liberación de óxido nítrico para agentes terapéuticos de óxido nítrico y aplicaciones biomédicas
JP2008303145A (ja) * 2005-09-22 2008-12-18 Takeda Chem Ind Ltd Ｇｒｋ阻害剤からなる強心薬
FR2914554B1 (fr) * 2007-04-05 2009-07-17 Germitec Soc Par Actions Simpl Procede de suivi de l'uitilisation d'un appareil medical.
WO2010042546A1 (en) 2008-10-06 2010-04-15 Indiana University Research And Technology Corporation Methods and apparatus for active or passive assistance in the circulatory system
WO2011022652A1 (en) 2009-08-21 2011-02-24 Novan, Inc. Topical gels
CA2771389C (en) 2009-08-21 2019-04-09 Novan, Inc. Wound dressings, methods of using the same and methods of forming the same
BR112012008508A2 (pt) * 2009-10-13 2017-06-13 Novan Inc revestimento de sol-gel, substrato, método para produzir um revestimento de sol-gel
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
WO2012118829A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Tertiary s-nitrosothiol-modified nitricoxide-releasing xerogels and methods of using the same
HUE052023T2 (hu) * 2016-05-27 2021-04-28 Ipsen Biopharm Ltd Triptofánnal vagy tirozinnal stabilizált folyékony neurotoxin készítmény
US11524023B2 (en) 2021-02-19 2022-12-13 Modernatx, Inc. Lipid nanoparticle compositions and methods of formulating the same

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476108A (en) * 1981-01-16 1984-10-09 Kessler Jack H Bactericidal method
JPS63208525A (ja) * 1987-02-25 1988-08-30 Kikkoman Corp 心不全治療剤
WO1992010228A1 (en) * 1990-12-05 1992-06-25 The General Hospital Corporation Devices for treating pulmonary vasoconstriction and asthma
US5380758A (en) * 1991-03-29 1995-01-10 Brigham And Women's Hospital S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
US5385937A (en) * 1991-04-10 1995-01-31 Brigham & Women's Hospital Nitrosation of homocysteine as a method for treating homocysteinemia
US5891459A (en) * 1993-06-11 1999-04-06 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
US5728705A (en) * 1993-10-04 1998-03-17 The Trustees Of Columbia University In The City Of New York Method of inducing vasorelaxation to treat pulmonary hypertension
US6063407A (en) * 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US5645839A (en) * 1995-06-07 1997-07-08 Trustees Of Boston University Combined use of angiotensin inhibitors and nitric oxide stimulators to treat fibrosis
US6197745B1 (en) * 1995-09-15 2001-03-06 Duke University Methods for producing nitrosated hemoglobins and therapeutic uses therefor
US6294517B1 (en) 1996-02-02 2001-09-25 Nitromed, Inc. Compositions and kits comprising alpha-adrenergic receptor antagonists and nitric oxide donors and methods of use
US5985862A (en) * 1996-05-02 1999-11-16 G.D. Searle & Co. Pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs
US6057367A (en) * 1996-08-30 2000-05-02 Duke University Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
EP1015490B1 (en) * 1997-02-06 2004-04-14 Duke University No-modified hemoglobins and uses therefor
WO1998043621A1 (en) * 1997-03-31 1998-10-08 The Children's Medical Center Corporation Nitrosylation to inactivate apoptotic enzymes
WO1998052580A1 (en) * 1997-05-21 1998-11-26 Duke University Treating asthma by preventing and/or accommodating for s-nitrosothiol breakdown
US6486206B1 (en) * 1997-09-29 2002-11-26 Cprx Inc. Mechanical and pharmacologic therapies to treat cardiac arrest
WO1999018949A1 (en) * 1997-10-15 1999-04-22 Thomas Jefferson University Nitric oxide donor compositions, methods, apparatus, and kits for preventing or alleviating vasoconstriction or vasospasm in a mammal
AU1770299A (en) 1997-12-23 1999-07-19 Nycomed Imaging As Nitric oxide releasing chelating agents and their therapeutic use
US6007824A (en) * 1998-07-09 1999-12-28 Duckett; Melvin J. Natural composition and method for the treatment of sexual dysfunction
EP1126838A4 (en) * 1998-10-30 2005-02-16 Nitromed Inc NITROSIS AND NITROSYAL NON-STEROID ANTI-INFLAMMATORY COMPOUNDS, COMPOSITIONS AND METHODS OF USE
US7045152B2 (en) * 1999-09-08 2006-05-16 Duke University Treating pulmonary disorders with gaseous agent causing repletion of GSNO
US6314956B1 (en) * 1999-09-08 2001-11-13 Duke University Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders
CA2410632A1 (en) * 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
CA2425489C (en) * 2000-10-16 2011-05-17 Duke University Therapeutic use of aerosolized s-nitrosoglutathione in cystic fibrosis
US6359182B1 (en) 2000-10-26 2002-03-19 Duke University C-nitroso compounds and use thereof
US7179791B2 (en) * 2001-01-11 2007-02-20 Duke University Inhibiting GS-FDH to modulate NO bioactivity
US6489206B2 (en) * 2001-03-22 2002-12-03 United Microelectronics Corp. Method for forming self-aligned local-halo metal-oxide-semiconductor device
US6627602B2 (en) * 2001-11-13 2003-09-30 Duke University Preventing desensitization of receptors
US6472390B1 (en) 2001-11-13 2002-10-29 Duke University Use of therapeutic dosages for nitric oxide donors which do not significantly lower blood pressure or pulmonary artery pressure

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