JP2006503901A5 - - Google Patents

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Publication number
JP2006503901A5
JP2006503901A5 JP2004548325A JP2004548325A JP2006503901A5 JP 2006503901 A5 JP2006503901 A5 JP 2006503901A5 JP 2004548325 A JP2004548325 A JP 2004548325A JP 2004548325 A JP2004548325 A JP 2004548325A JP 2006503901 A5 JP2006503901 A5 JP 2006503901A5
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JP
Japan
Prior art keywords
condition
composition
receptor
disease
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004548325A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006503901A (ja
JP4705783B2 (ja
Filing date
Publication date
Priority claimed from US10/280,085 external-priority patent/US6627602B2/en
Application filed filed Critical
Publication of JP2006503901A publication Critical patent/JP2006503901A/ja
Publication of JP2006503901A5 publication Critical patent/JP2006503901A5/ja
Application granted granted Critical
Publication of JP4705783B2 publication Critical patent/JP4705783B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2004548325A 2002-10-25 2003-10-20 レセプターの脱感作の予防 Expired - Fee Related JP4705783B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/280,085 2002-10-25
US10/280,085 US6627602B2 (en) 2001-11-13 2002-10-25 Preventing desensitization of receptors
PCT/US2003/029134 WO2004039313A2 (en) 2002-10-25 2003-10-20 Preventing desensitization of receptors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010101547A Division JP2010159307A (ja) 2002-10-25 2010-04-26 レセプターの脱感作の予防

Publications (3)

Publication Number Publication Date
JP2006503901A JP2006503901A (ja) 2006-02-02
JP2006503901A5 true JP2006503901A5 (https=) 2006-11-09
JP4705783B2 JP4705783B2 (ja) 2011-06-22

Family

ID=32228743

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2004548325A Expired - Fee Related JP4705783B2 (ja) 2002-10-25 2003-10-20 レセプターの脱感作の予防
JP2010101547A Withdrawn JP2010159307A (ja) 2002-10-25 2010-04-26 レセプターの脱感作の予防

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010101547A Withdrawn JP2010159307A (ja) 2002-10-25 2010-04-26 レセプターの脱感作の予防

Country Status (6)

Country Link
US (3) US6627602B2 (https=)
EP (1) EP1567182A4 (https=)
JP (2) JP4705783B2 (https=)
AU (1) AU2003287006B2 (https=)
CA (1) CA2503624A1 (https=)
WO (1) WO2004039313A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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US6627738B2 (en) * 1995-09-15 2003-09-30 Duke University No-modified hemoglobins and uses therefor
DE60141703D1 (de) * 2000-10-16 2010-05-12 Univ Duke Therapeutische anwendung von zerstäubtem s-nitrosoglutathion bei zystischer fibrose
WO2002036069A2 (en) * 2000-10-31 2002-05-10 Duke University Hypotension
US20040110691A1 (en) * 2001-11-13 2004-06-10 Stamler Jonathan S. Thiol reactive agents as a therapeutic modality
US6627602B2 (en) * 2001-11-13 2003-09-30 Duke University Preventing desensitization of receptors
GB0326047D0 (en) * 2003-11-07 2003-12-10 Univ Sheffield Substance
ES2543836T3 (es) * 2004-04-23 2015-08-24 Northern Sydney Local Health District Procedimientos y composiciones para el tratamiento de afecciones miocárdicas
EP1888510A4 (en) 2005-05-27 2013-01-16 Univ North Carolina NITROGEN OXIDE-RELATED PARTICLES FOR NITROGEN OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS
JP2008303145A (ja) * 2005-09-22 2008-12-18 Takeda Chem Ind Ltd Ｇｒｋ阻害剤からなる強心薬
FR2914554B1 (fr) * 2007-04-05 2009-07-17 Germitec Soc Par Actions Simpl Procede de suivi de l'uitilisation d'un appareil medical.
AU2009302471B2 (en) 2008-10-06 2015-03-19 Indiana University Research And Technology Corporation Methods and apparatus for active or passive assistance in the circulatory system
WO2011022652A1 (en) 2009-08-21 2011-02-24 Novan, Inc. Topical gels
BR112012003804B1 (pt) 2009-08-21 2019-02-19 Novan, Inc. Curativo para ferimentos, método para formar um curativo para ferimentos, e, kit de curativo para ferimento
WO2011047013A1 (en) * 2009-10-13 2011-04-21 Novan, Inc. Nitric oxide-releasing coatings
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
ES2695173T3 (es) 2011-02-28 2019-01-02 Novan Inc Partículas de sílice modificadas con S-nitrosotiol que liberan óxido nítrico y procedimientos de fabricación de las mismas
PL3463432T3 (pl) * 2016-05-27 2021-04-19 Ipsen Biopharm Limited Ciekła formulacja neurotoksyny stabilizowana tryptofanem lub tyrozyną
US11524023B2 (en) 2021-02-19 2022-12-13 Modernatx, Inc. Lipid nanoparticle compositions and methods of formulating the same

Family Cites Families (31)

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US4476108A (en) * 1981-01-16 1984-10-09 Kessler Jack H Bactericidal method
JPS63208525A (ja) * 1987-02-25 1988-08-30 Kikkoman Corp 心不全治療剤
EP1875917A3 (en) * 1990-12-05 2012-11-28 The General Hospital Corporation Use of NO for the treatment or prevention of reversible pulmonary vasoconstriction
US5380758A (en) * 1991-03-29 1995-01-10 Brigham And Women's Hospital S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
US5385937A (en) * 1991-04-10 1995-01-31 Brigham & Women's Hospital Nitrosation of homocysteine as a method for treating homocysteinemia
US5891459A (en) * 1993-06-11 1999-04-06 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
US5728705A (en) * 1993-10-04 1998-03-17 The Trustees Of Columbia University In The City Of New York Method of inducing vasorelaxation to treat pulmonary hypertension
US6063407A (en) * 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US5645839A (en) * 1995-06-07 1997-07-08 Trustees Of Boston University Combined use of angiotensin inhibitors and nitric oxide stimulators to treat fibrosis
US6197745B1 (en) * 1995-09-15 2001-03-06 Duke University Methods for producing nitrosated hemoglobins and therapeutic uses therefor
US6294517B1 (en) 1996-02-02 2001-09-25 Nitromed, Inc. Compositions and kits comprising alpha-adrenergic receptor antagonists and nitric oxide donors and methods of use
US5985862A (en) * 1996-05-02 1999-11-16 G.D. Searle & Co. Pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs
US6057367A (en) * 1996-08-30 2000-05-02 Duke University Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
JP2002513400A (ja) * 1997-02-06 2002-05-08 デューク ユニバーシティ メディカル センター Ｎｏ修飾ヘモグロビンおよびそのための使用
JP4777489B2 (ja) * 1997-03-31 2011-09-21 ザ チルドレンズ メディカル センター コーポレーション アポトーシス性酵素を不活性化するためのニトロシル化
US6617355B1 (en) * 1997-05-21 2003-09-09 The University Of Virginia Patent Foundation Treating asthma by preventing and/or accomodating S-nitrosothiol breakdown
US6486206B1 (en) * 1997-09-29 2002-11-26 Cprx Inc. Mechanical and pharmacologic therapies to treat cardiac arrest
US6358536B1 (en) * 1997-10-15 2002-03-19 Thomas Jefferson University Nitric oxide donor compositions, methods, apparatus, and kits for preventing or alleviating vasoconstriction or vasospasm in a mammal
AU1770299A (en) * 1997-12-23 1999-07-19 Nycomed Imaging As Nitric oxide releasing chelating agents and their therapeutic use
US6007824A (en) * 1998-07-09 1999-12-28 Duckett; Melvin J. Natural composition and method for the treatment of sexual dysfunction
US6297260B1 (en) * 1998-10-30 2001-10-02 Nitromed, Inc. Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use
US6314956B1 (en) * 1999-09-08 2001-11-13 Duke University Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders
US7045152B2 (en) * 1999-09-08 2006-05-16 Duke University Treating pulmonary disorders with gaseous agent causing repletion of GSNO
CA2410632A1 (en) * 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
DE60141703D1 (de) * 2000-10-16 2010-05-12 Univ Duke Therapeutische anwendung von zerstäubtem s-nitrosoglutathion bei zystischer fibrose
US6359182B1 (en) 2000-10-26 2002-03-19 Duke University C-nitroso compounds and use thereof
US7179791B2 (en) * 2001-01-11 2007-02-20 Duke University Inhibiting GS-FDH to modulate NO bioactivity
US6489206B2 (en) * 2001-03-22 2002-12-03 United Microelectronics Corp. Method for forming self-aligned local-halo metal-oxide-semiconductor device
US6627602B2 (en) * 2001-11-13 2003-09-30 Duke University Preventing desensitization of receptors
US6472390B1 (en) * 2001-11-13 2002-10-29 Duke University Use of therapeutic dosages for nitric oxide donors which do not significantly lower blood pressure or pulmonary artery pressure

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