JP2006503017A - Il−13要素及びt細胞エピトープを含む免疫原組成物並びにその治療上の使用 - Google Patents

Il−13要素及びt細胞エピトープを含む免疫原組成物並びにその治療上の使用 Download PDF

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Publication number
JP2006503017A
JP2006503017A JP2004532284A JP2004532284A JP2006503017A JP 2006503017 A JP2006503017 A JP 2006503017A JP 2004532284 A JP2004532284 A JP 2004532284A JP 2004532284 A JP2004532284 A JP 2004532284A JP 2006503017 A JP2006503017 A JP 2006503017A
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sequence
human
immunogen
immunogenic composition
substitutions
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JP2004532284A
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Japanese (ja)
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JP2006503017A5 (https=
Inventor
エリス,ジョナサン,ヘンリー
アシュマン,クレア
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Glaxo Group Ltd
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Glaxo Group Ltd
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Priority claimed from GB0220212A external-priority patent/GB0220212D0/en
Priority claimed from GB0304672A external-priority patent/GB0304672D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JP2006503017A publication Critical patent/JP2006503017A/ja
Publication of JP2006503017A5 publication Critical patent/JP2006503017A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5437IL-13
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2004532284A 2002-08-30 2003-08-28 Il−13要素及びt細胞エピトープを含む免疫原組成物並びにその治療上の使用 Pending JP2006503017A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0220212A GB0220212D0 (en) 2002-08-30 2002-08-30 Vaccine
GB0304672A GB0304672D0 (en) 2003-02-28 2003-02-28 Vaccines
PCT/GB2003/003703 WO2004019974A2 (en) 2002-08-30 2003-08-28 Immunogenic composition comprising an il-13 element and t cell epitopes, and its therapeutic use

Publications (2)

Publication Number Publication Date
JP2006503017A true JP2006503017A (ja) 2006-01-26
JP2006503017A5 JP2006503017A5 (https=) 2006-06-15

Family

ID=31980003

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004532284A Pending JP2006503017A (ja) 2002-08-30 2003-08-28 Il−13要素及びt細胞エピトープを含む免疫原組成物並びにその治療上の使用

Country Status (8)

Country Link
US (1) US20060147417A1 (https=)
EP (1) EP1532172A2 (https=)
JP (1) JP2006503017A (https=)
AR (1) AR041086A1 (https=)
AU (1) AU2003259358A1 (https=)
CA (1) CA2496409A1 (https=)
TW (1) TW200407162A (https=)
WO (1) WO2004019974A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010504094A (ja) * 2006-09-25 2010-02-12 エスジェイ バイオメッド インコーポレイテッド 抗肥満用免疫原性ハイブリッドポリペプチド及びこれを含む抗肥満ワクチン組成物(Anti−ObeseImmunogenicHybridPolypeptidesAndAnti−ObeseVaccineCompositionComprisingTheSame)
JP2020534874A (ja) * 2017-09-29 2020-12-03 ヴァクディアグン バイオテクノロジー カンパニー リミテッドVacdiagn Biotechnology Co., Ltd Cd4ヘルパーt細胞エピトープの融合ペプチドおよびそのワクチン

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006503018A (ja) * 2002-08-30 2006-01-26 グラクソ グループ リミテッド ワクチン
SG10201404273QA (en) 2003-12-23 2014-10-30 Genentech Inc Novel anti-il 13 antibodies and uses thereof
DE102004003572A1 (de) * 2004-01-23 2005-08-18 Bavarian Nordic A/S Monoparamunitätsinducer basierend auf attenuierten Myxomaviren des Kaninchens
KR100639397B1 (ko) * 2004-03-18 2006-10-26 (주)에스제이바이오메드 항비만용 면역원성 하이브리드 폴리펩타이드 및 이를포함하는 항비만 백신 조성물
JP2008520684A (ja) 2004-11-17 2008-06-19 アブジェニックス・インコーポレーテッド Il−13に対する完全ヒトモノクローナル抗体
GB0615881D0 (en) * 2006-08-10 2006-09-20 Univ Southampton Novel peptide for treatment of asthma
AU2010269120B2 (en) * 2009-07-06 2015-09-24 The Australian National University Immunomodulating compositions comprising interleukin 13 inhibitors and uses therefor
WO2015017034A1 (en) * 2013-08-02 2015-02-05 Gourdie Robert G Methods of treating a cancer through targeted disruption of alpha connexin 43-zonula occludens-1 (zo-1) interaction
ES2915378T3 (es) 2013-09-13 2022-06-22 Hoffmann La Roche Procedimientos para detectar y cuantificar una proteína de célula huésped en líneas celulares
EP4331605A3 (en) 2013-09-13 2024-05-22 F. Hoffmann-La Roche AG Methods and compositions comprising purified recombinant polypeptides
EP3574915A1 (en) 2018-05-29 2019-12-04 Neovacs Immunogenic product comprising il-4 and/or il-13 for treating disorders associated with aberrant il-4 and/or il 13 expression or activity
BR112021012668A2 (pt) 2018-12-28 2021-12-28 United Biomedical Inc Imunógenos de peptídeos que possuem como alvo interleucina 6 (il-6) e formulações dos mesmos para imunoterapia de doenças impactadas pela desregulação de il-6
CN117222664A (zh) * 2021-01-29 2023-12-12 拜耳动物保健有限责任公司 用于破坏自身耐受的疫苗组合物
WO2023021195A1 (en) * 2021-08-20 2023-02-23 Neovacs mRNA VACCINES COMPRISING IL-4 AND/OR IL-13 RNA AND USES THEREOF

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9717953D0 (en) * 1997-08-22 1997-10-29 Smithkline Beecham Biolog Vaccine
US6296843B1 (en) * 1998-04-03 2001-10-02 The Penn State Research Foundation Mutagenized IL 13-based chimeric molecules
TR200103046T2 (tr) * 1999-04-23 2002-06-21 Pharmexa A/S IL5 aktivitesini düşürmek için yöntem.
CA2404763A1 (en) * 1999-11-11 2001-05-17 Raj K. Puri Mutated il-13 molecules and their uses
US6846486B1 (en) * 2000-02-24 2005-01-25 Advanced Biotherapy Concepts, Inc. Method of treating allergy by administering an anti-histamine antibody
GB0105360D0 (en) * 2001-03-03 2001-04-18 Glaxo Group Ltd Chimaeric immunogens

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010504094A (ja) * 2006-09-25 2010-02-12 エスジェイ バイオメッド インコーポレイテッド 抗肥満用免疫原性ハイブリッドポリペプチド及びこれを含む抗肥満ワクチン組成物(Anti−ObeseImmunogenicHybridPolypeptidesAndAnti−ObeseVaccineCompositionComprisingTheSame)
JP2020534874A (ja) * 2017-09-29 2020-12-03 ヴァクディアグン バイオテクノロジー カンパニー リミテッドVacdiagn Biotechnology Co., Ltd Cd4ヘルパーt細胞エピトープの融合ペプチドおよびそのワクチン
JP7146926B2 (ja) 2017-09-29 2022-10-04 ヴァクディアグン バイオテクノロジー カンパニー リミテッド Cd4ヘルパーt細胞エピトープの融合ペプチドおよびそのワクチン

Also Published As

Publication number Publication date
TW200407162A (en) 2004-05-16
WO2004019974A3 (en) 2004-07-22
AR041086A1 (es) 2005-04-27
US20060147417A1 (en) 2006-07-06
EP1532172A2 (en) 2005-05-25
AU2003259358A8 (en) 2004-03-19
CA2496409A1 (en) 2004-03-11
WO2004019974A2 (en) 2004-03-11
AU2003259358A1 (en) 2004-03-19

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