JP2006188461A - Cosmetic - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide cosmetics stably compounded with ascorbic acid glucoside, hardly causing temporal discoloration and giving good use feelings. <P>SOLUTION: The cosmetics are compounded with following (a) to (c) components; (a) ascorbic acid glucoside, (b) a basic amino acid, and (c) a basic neutralizer. The cosmetics comprising an alkali metal hydroxide as the component (c) are provided. The cosmetics comprising arginine, histidine or lysine as the component (c) are also provided. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a cosmetic, and more particularly, to a cosmetic that is stably blended with ascorbic acid glucoside and has excellent usability.

  Conventionally, ascorbic acid and its derivatives are blended as whitening agents in order to give cosmetics an excellent whitening effect. Ascorbic acid suppresses the production of melanin by suppressing the reaction from dopaquinone, which is an intermediate product in the melanin production process in melanocytes, to dopachrome. In addition, it has the effect of reducing the generated colored oxidized melanin to colorless reduced melanin, and it is known as an effective compound for skin whitening, spots and freckles, scleroderma and melasma. However, ascorbic acid has the disadvantage of being easily oxidized and chemically unstable.

From recent research, ascorbic acid glucoside was discovered as a stable ascorbic acid derivative that is not easily oxidized, and is widely incorporated in cosmetics. However, cosmetics containing ascorbic acid glucoside have a problem in stability such that the color changes with time. In order to solve this problem, Patent Documents 1 and 2 propose cosmetics in which a strong base substance is blended with ascorbic acid glucoside.
JP 2001-199863 A (pages 1 to 4) JP 2003-012498 A (page 1 to page 7)

  However, when a strong base substance such as sodium hydroxide is used as a neutralizing agent for ascorbic acid glucoside, stickiness derived from ascorbic acid glucoside may occur. Moreover, the softness | flexibility of the skin after apply | coating cosmetics to skin was also not enough. As a result of intensive studies to solve the above-mentioned problems, the present inventor, as a result of blending a basic amino acid into a cosmetic blended with ascorbic acid glucoside and a basic neutralizing agent, feel of the ascorbic acid glucoside blended cosmetic. The present inventors have found that the above stickiness is reduced and the skin flexibility is also improved, and the present invention has been completed.

  That is, the present invention is a cosmetic comprising the component (a) ascorbic acid glucoside, the component (b) a basic amino acid, and (c) a basic neutralizing agent. Furthermore, the cosmetic is characterized in that the component (c) is an alkali metal hydroxide. Further, the cosmetic is characterized in that the component (b) is arginine, histidine, or lysine, the compounding amount of the component (a) is 1 to 5% by mass, and the compounding amount of the component (b) is 0. 0.1-2% by mass, and the amount of component (c) is 0.001-0.8% by mass. And the compounding mass ratio of a component (a) and a component (b) is (a) :( b) = 30: 1-1: 1, It is a cosmetic characterized by the above-mentioned.

  According to the present invention, not only can ascorbic acid glucoside be stably added, but also the stickiness on the feel derived from ascorbic acid glucoside can be reduced, and further, skin can be given flexibility, and skin care effects In addition, excellent cosmetics can be provided.

  Hereinafter, the configuration of the present invention will be described in detail.

  The component (a) ascorbic acid glucoside used in the present invention is blended for the purpose of whitening effect. Among them, α-glucosyl-L-ascorbic acid is preferable, since whitening effect can be easily obtained and its own stability is good, and 2-O-α-D-glucosyl-L-ascorbic acid is particularly preferable. And can be produced by the method described in JP-A-3-139288.

  The amount of the ascorbic acid glucoside as the component (a) used in the present invention is not particularly limited, but is preferably 0.01 to 10% by mass (hereinafter abbreviated as%), more preferably 1 to 5%. It is. Within this range, the whitening effect is excellent, and good stability over time is obtained, which is preferable.

  The basic amino acid of the component (b) used in the present invention reduces the stickiness of the cosmetics containing the component (a), and makes the skin soft after application of the cosmetics. It is blended for the purpose of improving the stability over time.

  Examples of the basic amino acid of component (b) include arginine, histidine, lysine and the like.

  The amount of component (b) is preferably 0.01 to 10%, more preferably, in order to further reduce the stickiness of the cosmetic and to further improve the flexibility of the skin after applying the cosmetic. 0.1-2%.

  The basic neutralizer of component (c) is blended for the purpose of partial neutralization or complete neutralization of component (a), and is an essential component in the present application in order to improve the temporal stability. is there.

  Component (c) basic neutralizers include sodium hydroxide, potassium hydroxide, calcium hydroxide, magnesium hydroxide, sodium carbonate, monoethanolamine, diethanolamine, triethanolamine, isopropanolamine, diisopropanolamine, Examples include isopropanolamine, 2-amino-2-methyl-1-propanol, 2-amino-2-methyl-1,3-propanediol. Among these, alkali metal hydroxides such as sodium hydroxide and potassium hydroxide are preferable in order to further improve the temporal stability.

  The blending amount of component (c) is preferably 0.0001-3%, more preferably 0.001-0.8%. Within this range, it is preferable because good temporal stability can be obtained.

  The blending mass ratio of the component (a) and the component (b) used in the present invention is preferably 50: 1 to 2: 3, more preferably 30: 1 to 1: 1. If it is this range, stickiness will be suppressed and favorable temporal stability will be obtained, and it is preferable.

  In a liquid cosmetic that does not contain a large amount of oil or water-soluble polymer, the effects of the present invention are more remarkably exhibited. Stickiness derived from ascorbic acid glucoside is more noticeable in liquid cosmetics that do not contain a large amount of oil or water-soluble polymer, and reduces stickiness even when using conventional techniques such as Patent Document 1. That was not enough. The liquid cosmetic referred to herein is one having a viscosity at 25 ° C. measured with a Brookfield rotary viscometer and a viscosity at 25 ° C. of 1 to 2000 mPa · s. When the viscosity is in this range, it is possible to obtain a fresh feeling without stickiness. Moreover, in this invention, it is preferable that the compounding quantity of an oil component is less than 1%.

  In the present invention, from the viewpoint of the stability of ascorbic acid glucoside, the pH of the cosmetic is preferably 5 to 8 at 25 ° C.

  The dosage form of the cosmetic of the present invention is not particularly limited, and can be applied to any dosage form of water, solubilization, oil-in-water, water-in-oil, and oil. Among them, the water-based, solubilized, and oil-in-water-based aqueous dosage forms can remarkably obtain the effects of the present invention.

  In addition to the above essential components, the cosmetics of the present invention include oils, surfactants, water-soluble polymers, antioxidants, pH adjusters, fragrances, antibacterial agents, preservatives, cosmetic ingredients, and the like. It can mix | blend in the range which does not impair an effect.

  Applications of the cosmetics of the present invention can be exemplified by lotions, cosmetic liquids, body lotions, milky lotions, creams, packs, massages, sunscreens, cleansings, foundations, foundations, point makeup cosmetics, etc. Examples of the method of use include a method of using by hand, a method of using by impregnating a nonwoven fabric, a method of using by filling an aerosol, and the like.

  EXAMPLES Next, although an Example is given and this invention is further demonstrated, this invention is not limited at all by this.

Examples 1 to 7 and Comparative Examples 1 to 5: Lotion Toner lotions having the compositions shown in Table 1 were prepared by the following production method. The obtained lotion (1) whitening effect, (2) stability (no discoloration), (3) feeling of use (no stickiness), and (4) skin softness were evaluated by the following methods. The results are also shown in Table 1.

(Production method)
A: Components (1) to (5) are uniformly dissolved.
B: Components (6) to (17) are uniformly dissolved.
C: A was added to B to obtain a skin lotion.

(Evaluation methods)
About each sample of Examples 1-7 and Comparative Examples 1-5, (1) whitening effect, (2) temporal stability (no discoloration), (3) feeling of use (no stickiness), (4) skin The flexibility was evaluated by the following method.

[Whitening effect; test method, evaluation method]
The skin whitening effect after each sample was applied to the face twice a day (morning and evening) for 1 month was evaluated by 5 cosmetic evaluation panels for each sample based on the following criteria, and evaluated from the average score. .

[Evaluation criteria]
5 points: Clearly whitening effect 4 points: Whitening effect 3 points: Some whitening effect is seen 2 points: Little whitening effect is seen 1 point: No whitening effect is seen at all [Criteria]
○: Average point 4.5 points or more ×: Average point less than 4.5 points

[Stability evaluation over time; test method, evaluation method]
Samples were set in a thermostatic bath at 50 ° C. and left for one month, and then the color change of each sample was visually observed and evaluated according to the following criteria.

[Criteria]
◎: No discoloration was observed at all ○: Almost no discoloration was observed Δ: Slightly changed to yellow ×: Clearly changed to yellow

[Usability: test method, evaluation method]
Ten cosmetic evaluation panels evaluated the feeling of use (non-stickiness) when applied to the face and the flexibility of the skin after use, based on the following criteria, and further determined from the average score.

[Evaluation criteria]
5 points: Very good 4 points: Good 3 points: Normal 2 points: Bad 1 point: Very bad [Criteria]
◎: Average point 4.5 points or more ○: Average point 3.5 points or more and less than 4.5 points ×: Average point less than 3.5 points

  As is apparent from the results in Table 1, Examples 1 to 7 according to the present invention are (1) whitening effect, (2) stability over time (no discoloration), and (3) usability compared with the comparative examples. (No stickiness), (4) A lotion with excellent skin flexibility after use. On the other hand, Comparative Example 1 in which ascorbic acid glucoside is not blended has no whitening effect, and Comparative Examples 2 to 5 in which no basic amino acid and basic neutralizer are blended has the same whitening effect, but is stable over time. The usability was not good.

Example 8: Lotion (Ingredient) (%)
1. Polyoxyethylene isostearate (50) hydrogenated castor oil 0.5
2. Sorbitan sesquioleate 0.1
3. Tetra-2-ethylhexanoic acid pentaerythrit 0.6
4). Ethanol 10
5). Perfume appropriate amount 6. 6. Purified water remaining amount Citric acid 0.1
8). Sodium citrate 0.1
9. 2-O-α-D-glucosyl-L-ascorbic acid (Note 1) 2.0
10. Arginine (Note 2) 0.5
11. Histidine (Note 2) 0.5
12 Sodium hydroxide 0.12
13. Edetate disodium 0.1
14 Glycerin 10

(Manufacturing method)
A: Components (1) to (5) are uniformly dissolved.
B: Components (6) to (14) are uniformly dissolved.
C: A was added to B to obtain a skin lotion.

  The lotion of Example 8 was a non-sticky lotion having a pH of 7 at 25 ° C., a high whitening effect and excellent stability over time.

Example 9: serum
(Ingredient) (%)
1. Polyoxyethylene (20) sorbitan monooleate 1.0
2. Sorbitan sesquioleate 0.5
3. Glyceryl trioctanoate 0.5
4). Jojoba oil 0.5
5). Squalane 0.5
6). 6. Purified water remaining amount Edetate disodium 0.1
8). Methylparaben 0.2
9. Phenoxyethanol 0.5
10. Glycerin 5.0
11. Sodium lactate 0.5
12.2-O-α-D-glucosyl-L-ascorbic acid (Note 1) 1.0
13. Arginine (Note 2) 0.2
14 Ricin (Note 2) 0.3
15. Potassium hydroxide 0.2
16. Xanthan gum 0.05
17. Purified water 10.0
18. Ethanol 3.0
19. Perfume

(Manufacturing method)
A: The component (16) is swollen with the component (17) heated to 70 ° C.
B: Components (1) to (5) are dissolved by heating at 70 ° C.
C: Components (6) to (15) are heated and dissolved at 70 ° C., then added to B and emulsified.
D: After cooling C to room temperature, components (18), (19) and A were added to obtain a cosmetic liquid.

The serum of Example 9 had a pH of 6.5 at 25 ° C., had a high whitening effect, was excellent in stability over time, and was a non-sticky serum.

Claims (5)

The following components (a) to (c);
(A) Ascorbic acid glucoside (b) Basic amino acid (c) A cosmetic comprising a basic neutralizing agent.   The cosmetic according to claim 1, wherein the component (c) is an alkali metal hydroxide.   The cosmetic according to claim 1 or 2, wherein the component (b) is one or more selected from arginine, histidine, and lysine.   The amount of component (a) is 1 to 5% by mass, the amount of component (b) is 0.1 to 2% by mass, and the amount of component (c) is 0.001 to 0.8%. The cosmetic according to any one of claims 1 to 3, wherein the cosmetic is mass%.   The blending mass ratio of component (a) and component (b) is (a) :( b) = 30: 1 to 1: 1, The cosmetic according to any one of claims 1 to 4, .