JP2006160822A - Liquid detergent for clothes - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a liquid detergent for clothes which is used by diluting it with a large excess amount of water in a washing machine, wherein it has high antimicrobial activity even in a low antimicrobial concentration; and it has antimicrobial effect for Gram-negative bacteria and fungi without using other antimicrobial agents in combination. <P>SOLUTION: The liquid detergent for clothes comprises from 0.05 mass% to less than 1 mass% of a biguanide compound (a) and from 2 mass% to less than 50 mass% of one or more surfactants (b) selected from a polyoxyalkylene alkyl ether surfactant (b1) having a polyoxyalkylene group having an average addition molar number of 5-20, an alkylglycoside surfactant (b2) having an 8-16C alkyl group and an average degree of condensation of 1-2, and an amine oxide surfactant (b3) having one 8-18C hydrocarbon group, wherein component (a)/component (b) is 1/20-1/500 in the mass ratio. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a liquid cleaning agent for clothing.

The technique of a liquid detergent containing a biguanide compound as an antibacterial agent is already known, and Patent Documents 1 and 2 can be referred to. In addition, these patent documents also describe the combined use with a surfactant such as a nonionic surfactant.
JP-A-62-132806, JP 2004-203818 A

  Antibacterial effects have been applied to liquid cleaning agents for clothing for the purpose of preventing raw dry odor and sweat odor during indoor drying, and quaternary ammonium type antibacterial agents are mainly used. Further, the quaternary ammonium salt type antibacterial agent needs a concentration of 10 ppm or more in order to exhibit the antibacterial effect in the cleaning liquid. On the other hand, since the cleaning agent for clothing is diluted with a large excess of water in a washing machine, the concentration of the antibacterial agent in the cleaning agent is set to obtain a concentration of the antibacterial agent that exhibits a preferable antibacterial action in the cleaning liquid. In addition to being uneconomical, there is a problem in that other compounding components in the cleaning agent are pressed and the degree of freedom in compounding design is reduced. For this reason, the technique which can provide a high antimicrobial effect even if the density | concentration in a washing | cleaning liquid is low is calculated | required.

  On the other hand, biguanide compounds are known to have antibacterial activity, but have a problem that the antibacterial spectrum is narrow, such as a low antibacterial effect and a weak antibacterial effect for gram-negative bacteria and fungi. For this reason, Patent Document 1 discloses a technique for using in combination with another antibacterial agent such as a quaternary ammonium compound. Patent Document 2 discloses a technique applied to a sterilizing cleaning agent and an antibacterial deodorizing agent for toilets, and a nonionic surfactant is used as a cleaning component. However, the biguanide compound has almost no antibacterial effect at a low concentration, and the biguanide compound is used at a concentration of 1 ppm or more in all of the usage methods described in these publications, and the biguanide compound is generally used as an antibacterial agent. In some cases, the biguanide compound concentration during use is set high. Therefore, as described in the above prior art, biguanide compounds are used for hard surface applications that do not dilute to a large excess of water, and are diluted to a large excess of water in a washing machine. The biguanide-type antibacterial agent could not be applied to the laundry detergent used.

  The problem to be solved by the present invention is that a detergent for clothes used after being diluted with a large excess of water in a washing machine has high antibacterial activity even at a low concentration of antibacterial agent, and other antibacterial agents are used. An object of the present invention is to provide a liquid detergent for clothing having an antibacterial effect against gram-negative bacteria and fungi without using them in combination.

  In the present invention, the biguanide compound (a) (hereinafter referred to as the component (a)) is 0.05% by mass or more and less than 1% by mass, a hydrocarbon group having 8 to 18 carbon atoms and an average added mole number 5 to 20 poly. Polyoxyalkylene alkyl ether surfactant (b1) having an oxyalkylene group, alkylglycoside surfactant (b2) having an alkyl group having 8 to 16 carbon atoms and an average degree of condensation of 1 to 2, carbon number 8 1 to 1 or more surfactants (b) [hereinafter referred to as component (b)] selected from amine oxide surfactants (b3) having one hydrocarbon group of ˜18 to 2% by mass or more and 50% by mass It is related with the liquid detergent for clothes which contains less than% and is a mass ratio of (a) component / (b) component = 1 / 20-1 / 500.

  Moreover, this invention relates to the washing | cleaning method of the clothing which dilutes and wash | cleans the liquid cleaning agent for clothing of the said invention so that the density | concentration of (a) component may be 0.05 ppm-5 ppm.

  According to the present invention, a liquid detergent for clothing having high antibacterial activity even at a low concentration of antibacterial agent and having antibacterial effects against gram-negative bacteria and fungi can be obtained without using other antibacterial agents in combination. .

<(A) component>
The component (a) of the present invention is preferably an antibacterial biguanide compound. Here, the antibacterial biguanide compound is a compound having an antibacterial activity that has at least one site having a structure represented by the following general formula (1) in the molecule.

  In particular, the polyalkylene biguanide compound represented by the following general formula (2) is suitable.

[Wherein R ^2a is an alkylene group having 2 to 8 carbon atoms, preferably an alkylene group having 4 to 8 carbon atoms, particularly a hexamethylene group, and n is 2 to 14, preferably 10 to 14, more preferably 11 to 13, particularly 12 Is most preferred. HY represents an organic acid or an inorganic acid, preferably hydrochloric acid, gluconic acid, or acetic acid, and most preferably hydrochloric acid. ]

  As the biguanide compound of the general formula (2), a commercially available one may be used, but one produced by a known method such as the method described in British Patent No. 702268 may be used.

As the biguanide compound according to the method of the present invention, a bis-biguanide compound can be used in addition to the compound of the general formula (2). Specifically, 1,2-bis- (N ⁵ -p-chlorophenyl-N ¹ -biguanide) -ethane, 1,2-bis- (N ⁵ -p-nitrophenyl-N ¹ -biguanide) -ethane, , 2-bis - (N ^{5-p-hydroxyphenyl} -N ¹ - biguanide) - ethane, 1,2-bis - (N ^{5-p-chlorobenzyl} -N ¹ - biguanide) - ethane, 1,2-bis - (N ^{5-p-bromophenyl} -N ⁵ - hexyl -N ¹ - biguanide) - ethane, 1,2-bis - (N ^{5-p-chlorophenyl} -N ^{5-2-ethylphenyl} -N ¹ - biguanide) - ethane, 1,2-bis - (N ^{5-p-chlorophenyl} -N ⁵ - ethyl -N ¹ - biguanide) - ethane, 1,2-bis - (N ^{5-p-methoxyphenyl} -N ¹ - biguanide) -Ethane can be used.

The antibacterial biguanide compound according to the present invention is most preferably polyhexamethylene biguanide hydrochloride in which R ^2a is a hexamethylene group and n is 10 to 14 in the general formula (2) from the viewpoint of antibacterial activity at a low concentration. is there.

<(B) component>
The component (b) of the present invention comprises a polyoxyalkylene alkyl ether surfactant (b1) [hereinafter referred to as (b1) having a hydrocarbon group having 8 to 18 carbon atoms and a polyoxyalkylene group having an average addition mole number of 5 to 20. ) Component], alkylglycoside surfactant (b2) [hereinafter referred to as component (b2)] having an alkyl group having 8 to 16 carbon atoms and an average degree of condensation of 1 to 2, carbonization having 8 to 18 carbon atoms One or more surfactants selected from amine oxide type surfactants (b3) [hereinafter referred to as component (b3)] having one hydrogen group.

  As the polyoxyalkylene alkyl ether type surfactant as the component (b1), the compound (b11) of the following general formula (3) [hereinafter referred to as the component (b11)] and the compound (b12) of the following general formula (4) [ (Hereinafter referred to as component (b12)) is preferred.

^{_{R 3a - (OC 2 H 4}} ) p -OH (3)
_{^{R 4a - [(OC 2 H}} 4) q / (OC 3 H 6) r] -OH (4)

[Wherein R ^3a and R ^4a are alkyl groups having 8 to 18 carbon atoms, preferably 10 to 14 carbon atoms, and p is 5 to 20, preferably 5 to 15 and particularly preferably 5 to 10. q is 0-20, preferably 0.5-5, particularly preferably 0.5-3, r is 1-20, q + r is 5-20, preferably 5-15, particularly preferably 7-. 15. In addition, p, q, and r are average addition mole numbers. The arrangement of (OC ₂ H ₄ ) and (OC ₃ H ₆ ) in the general formula (3) may be block or random. ]

  Among the compounds of the general formula (4) as the component (b12), the compounds of the following general formula (4-1) are preferable from the viewpoint of detergency and the antibacterial effect at a low concentration of the component (a).

^{_{R 4a - (OC 2 H 4}} ) s (OC 3 H 6) t (OC 2 H 4) u -OH (4-1)

[Wherein R ^4a has the same meaning as described above, and s> 0, t = 1 to 4, u> 0, s + t + u = 6 to 14, and s + u = 5 to 12. Preferably, s + t + u = 7 to 14, s + u = 6 to 12, and t = 1 to 2. It is a block polymerized compound. ]

  As the alkylglycoside surfactant as the component (b2), a compound represented by the following general formula (5) is preferable.

R ^5a − (OR ^5b ) _v Gw (5)
[Wherein, R ^5a is a linear alkyl group having 8 to 16 carbon atoms, and R ^5b is an alkylene group having 2 to 4 carbon atoms. G represents a group derived from a reducing sugar. v is the average number of moles added and represents a number from 0 to 5, w is the average degree of condensation and represents a number from 1 to 2. ]

In general formula (5), R ^5a is preferably a linear alkyl group having 8 to 14 carbon atoms, particularly preferably a linear alkyl group having 10 to 14 carbon atoms. Further, v is preferably 0 to 3, more preferably 0 to 2, particularly preferably 0. R ^5b is preferably an ethylene group.

  In the general formula (5), G is a group derived from a reducing sugar, and more specifically a glycoside group. The reducing sugar as a raw material may be either aldose or ketose, and examples thereof include triose, tetrose, pentose, and hexose having 3 to 6 carbon atoms. Specific examples of aldose include apiose, arabinose, galactose, glucose, lyxose, mannose, idose, talose, and xylose. Examples of ketose include fructose. In the present invention, among these, aldopentose or aldohexose having 5 or 6 carbon atoms is particularly preferred, and glucose is most preferred.

  In general formula (5), w represents the average degree of condensation of sugars, preferably 1 to 2, particularly 1 to 1.5.

The compound of the general formula (5) can be easily synthesized by acetalizing or ketalizing the above sugar and R ^5a — (OR ^5b ) _v —OH using an acid catalyst. In the case of an acetalization reaction, a hemiacetal structure or a normal acetal structure may be used.

  As the compound of component (b3), a compound of the following general formula (6) is suitable.

[Wherein, R ^6a is an alkyl group or alkenyl group having 8 to 16 carbon atoms, R ^6b is an alkylene group having 1 to 6 carbon atoms, and B is —COO—, —CONH—, —OCO—, — It is a group selected from NHCO-. x is a number of 0 or 1, and R ^6c and R ^6d are each an alkyl group having 1 to 3 carbon atoms or a hydroxyalkyl group. ]

In the general formula (6), R ^6a is preferably an alkyl group having 10 to 14 carbon atoms, x is preferably 0, and R ^6c and R ^6d are methyl groups, from the viewpoint of improving antibacterial activity at low concentrations. Is preferred.

  In the present invention, the component (b1) is preferable as the component (b) from the viewpoint of antibacterial effect at a low concentration, and the component (b12) of the general formula (4) is particularly preferable, and the compound of the general formula (4-1) is most preferable. It is.

<Liquid detergent for clothing>
The present inventors have used a large excess of the component (b) in combination with the component (a) at a low concentration where the component (a) alone has low or no antibacterial effect. It has been found that the antibacterial effect can be significantly improved.

  That is, in the present invention, (a) component / (b) component = 1/20 to 1/500, preferably 1/50 to 1/500 in mass ratio, so that (a) component alone has an antibacterial effect. Excellent antibacterial effect can be obtained even at a low concentration that is low or does not show any antibacterial effect.

  In general, since an antibacterial biguanide compound has a surface active action, an aggregate is formed when used at a relatively high concentration, which is presumed to have an antibacterial action. On the other hand, in a dilute solution, the antibacterial biguanide compound does not form an aggregate and is uniformly dissolved in the aqueous solution, so it is considered that the antibacterial activity is not exhibited or satisfactory antibacterial activity cannot be obtained.

  In the present invention, the antibacterial biguanide compound is concentrated to some extent in the micelle of the specific surfactant or in the vicinity of the micelle by using a specific surfactant in a specific mass ratio with respect to the antibacterial biguanide compound. The antibacterial biguanide compound is presumed to exhibit antibacterial activity even at low concentrations. Further, it is presumed that the specific surfactant acts on the cell wall of the fungus to increase the permeability of the antibacterial biguanide compound and promote its effect, so that the antibacterial spectrum can be broadened.

  In the present invention, when the component (b11) is employed as the component (b), the mass ratio of the component (a) / (b11) is preferably 1/30 to 1/500, more preferably 1/40 to 1 / 500, particularly preferably 1/50 to 1/500. When the component (b12) is employed, the mass ratio of the component (a) / (b12) is preferably 1/20 to 1/500, more preferably 1/20 to 1/400, and particularly preferably Is 1/20 to 1/300. When the component (b2) is employed as the component (b), the mass ratio of the component (a) / (b2) is preferably 1/30 to 1/500, more preferably 1/40 to 1/400. Particularly preferably, the ratio is 1/50 to 1/400, and when the component (b3) is employed, the mass ratio with the component (a) / (b3) is preferably 1/30 to 1/500, more preferably It is 1/40 to 1/500, and particularly preferably 1/50 to 1/400.

  In the liquid detergent for clothes of the present invention, the component (a) is 0.05% by mass or more and less than 1% by mass, preferably 0.1% by mass or more and less than 1% by mass, particularly 0.1% by mass or more, 0 Less than 5% by mass is preferable. Moreover, (b) is 2 mass% or more and less than 50 mass%, Preferably it is 10 mass% or more and less than 50 mass%.

  The liquid detergent for clothing of the present invention is preferably in the form of a liquid composition in which the component (a) and the component (b) are dissolved or dispersed in water, and ion exchange in which a trace amount of metal components present in water is removed. Water, distilled water, or sterile water sterilized with hypochlorite or chlorine can be used.

  The pH of the liquid detergent for clothing of the present invention at 20 ° C. is preferably 7 to 12, and more preferably 8 to 11. pH adjusters include monoethanolamine, diethanolamine, triethanolamine, methylmonoethanolamine, dimethylethanolamine, amines such as 3-aminopropanol, alkali metal hydroxides such as sodium hydroxide and potassium hydroxide, sodium carbonate It is preferable to add an alkali agent such as an alkali metal carbonate such as potassium carbonate, an alkali metal silicate such as sodium silicate or potassium silicate, among which alkali metal carbonate such as sodium carbonate or potassium carbonate is a point of cleaning performance. Is preferable. These alkali agents are preferably contained in the cleaning agent in an amount of 0.5 to 30% by mass, more preferably 1 to 25% by mass, and still more preferably 3 to 20% by mass. It is also possible to use acid agents together for fine adjustment of pH, inorganic acids such as hydrochloric acid and sulfuric acid, organic acids such as citric acid, succinic acid, malic acid, fumaric acid, tartaric acid, malonic acid, maleic acid, etc. The acid agent can be used.

<Other ingredients>
The liquid detergent for clothing of the present invention can be used in combination with a surfactant other than the component (b), but it is desirable to determine the blending amount in consideration of the effect of the component (a). In particular, since an anionic surfactant reduces the effect of the component (a), the content thereof is 5% by mass or less, preferably 1% by mass or less, particularly preferably 0.5% by mass or less in the cleaning agent. . The anionic surfactant referred to here has at least one hydrocarbon group having 8 to 18 carbon atoms and one or more sulfonate, carboxylate, sulfate ester salt in the molecule, and an ammonium group. It is a compound which does not have.

  The cationic surfactant is preferably contained because the effect of the component (a) can be enhanced. As a preferred cationic surfactant, a compound of the following general formula (7) is suitable.

[Wherein R ^7a is a hydrocarbon group having 8 to 18 carbon atoms, preferably an alkyl group, R ^7b is an alkylene group having 2 or 3 carbon atoms, R ^7c is an alkyl group having 1 to 3 carbon atoms, carbon It is a hydroxyalkyl group of formula 2 or 3, a benzyl group, or R ^7a — [ ^{ER 7b} ] _y —. E is a group selected from —COO— and —CONH—, y is a number of 0 or 1, R ^7d and R ^7e are alkyl groups having 1 to 3 carbon atoms, and hydroxyalkyl groups having 2 or 3 carbon atoms. It is. Z ⁻ represents an anion, preferably a halogen ion or an alkyl sulfate ion having 1 to 3 carbon atoms. ]

  Specifically, (i) dialkyldimethylammonium chloride having 10 to 18 carbon atoms, (ii) N, N-dialkanoylaminopropyl-N, N-dimethylammonium chloride having 14 to 18 carbon atoms, and (iii) 14 carbon atoms. -18 N, N-dialkanoyloxyethyl-N-hydroxyethyl-N-methylammonium ethylsulfate, (iv) N-alkyl-N, N-dimethyl-N-benzylammonium chloride having 8 to 12 carbon atoms (V) One or more selected from N-alkanoylaminopropyl-N, N, N-trimethylammonium chloride is preferred.

  When a cationic surfactant is used in combination with the present invention, it is an amount that does not interfere with the effect of the component (a), and is preferably 0.1 to 10% by mass, preferably 0.1 to 5% in the cleaning agent. % By mass.

  In addition to the above components, the liquid detergent for clothing of the present invention includes (1) nitrilotriacetic acid, iminodiacetic acid, ethylenediaminetetraacetic acid, diethylenetriaminepentaacetic acid, glycol etherdiaminetetraacetic acid, hydroxyethyliminodiacetic acid, triethylenetetraamine Aminopolyacetic acid such as hexaacetic acid and diencoric acid or salts thereof, diglycolic acid, oxydisuccinic acid, carboxymethyloxysuccinic acid, citric acid, lactic acid, tartaric acid, oxalic acid, malic acid, oxydisuccinic acid, gluconic acid, carboxymethyl succinic acid, Organic acids such as carboxymethyl tartaric acid or salts thereof, polyacrylic acid, polymaleate, carboxymethyl cellulose, acrylic acid-maleic acid copolymer or salt thereof, maleic anhydride-diisobutylene copolymer or salt thereof, maleic anhydride Acid-meth A vinyl ether copolymer or a salt thereof, a maleic anhydride-isobutylene copolymer or a salt thereof, a maleic anhydride-vinyl acetate copolymer or a salt thereof, and claims 1 to 21 (1) of JP-A-59-62614 Organic polycarboxylic acids such as polymers described in page 3 column 5 line 3 page 4 column 14 line) and / or salts thereof 0.01 to 10% by mass, (2) alcohols such as ethanol, ethylene glycol and propylene glycol Glycols such as paratoluenesulfonic acid, benzoate (also effective as a preservative), and 0.01-30% by mass of a thickener and solubilizer such as urea, (3) polyoxyalkylene benzyl ether, Phase modifiers such as polyoxyalkylene phenyl ether and detergency improver 0.01 to 30% by mass, (4) average molecular weight 5000 Recontamination inhibitor and dispersant such as polyethylene glycol and naphthalene sulfonate formalin condensate 0.01 to 10% by mass, (5) 0.01 to 10% by mass of color transfer inhibitor such as polyvinyl pyrrolidone, (6 ) 0.01 to 10% by weight of bleaching agent such as sodium percarbonate or sodium perborate, (7) tetraacetylethylenediamine, represented by general formulas (I-2) to (I-7) of JP-A-6-316700 Bleach activators such as bleach activators 0.01 to 10% by mass, (8) Fluorescent dyes 0.001 to 1 such as Chino Pearl CBS (manufactured by Ciba Specialty Chemicals) and Whitetex SA (manufactured by Sumitomo Chemical) 1% by mass, (9) 0.1-2% by mass of a soft base such as silicone according to claim 1 of JP-A-10-60480, and (10) 0.01-2% by mass of an antifoaming agent such as silica. %, (11) Antioxidant 0.01-2% by mass, such as butylhydroxytoluene, distyrenated cresol, sodium sulfite and sodium hydrogen sulfite, (12) Bluening agent, (13) Cellulase, amylase, pectinase, protease, Enzymes such as lipase, (14) Enzyme stabilizers such as calcium chloride, calcium sulfate, formic acid, boric acid (boron compound), (15) Perfume, (16) Other antibacterial preservatives, (17) Colorants, etc. Can be blended.

<Washing method>
The detergent for clothes of the present invention is diluted with a large excess of water and used for washing clothes. The amount of water to be diluted is such that the concentration of the component (a) in the diluted solution is 0.05 ppm to 5 ppm, preferably 0.1 to 4 ppm. It is possible to obtain the effects of the invention. Specifically, it is used by diluting 1000 parts by weight to 10,000 parts by weight, and preferably 1000 parts by weight to 5000 parts by weight of water with respect to 1 part by weight of the detergent for clothing of the present invention. Moreover, the ratio of 1-20 mass parts of the cleaning agent of this invention with respect to 1000 mass parts of clothing to wash | clean, Suitably 5-15 mass parts is preferable. Furthermore, the concentration of the component (b) in the diluted solution is preferably 2 to 500 ppm, and more preferably 50 to 400 ppm from the viewpoint of detergency and antibacterial effect.

  In this invention, it can wash | clean with a washing machine using such a dilution liquid, The temperature of a dilution liquid is 5-40 degreeC suitably, Preferably it is 10-30 degreeC, and it is 5 to 20 minutes at this temperature. It is preferably washed for 5 to 15 minutes. After washing, normal rinsing / dehydration is performed, followed by natural drying or drying with a rotary heat drying apparatus.

  The liquid detergent for clothes shown in Table 1 was prepared. The antibacterial properties of solution A in which 20 g of the liquid detergent for clothing was dissolved in 30 liters of tap water were evaluated by the following method, and the results are also shown in Table 1. In addition, the density | concentration of (a) component in this solution A is 0.7 ppm in Examples 1-3 and the comparative example 1, and is 20 ppm in the comparative example 2. FIG.

<Evaluation of antibacterial properties>
Escherichia coli (IFO 3972) and Staphylococcus aureus (IFO 12732) are used as test bacteria. IFO3972 and IFO12732 are deposited and available at the Fermentation Research Institute, 2-17-85 Juzahoncho, Yodogawa-ku, Osaka.

In 0.9 ml of solution A, 0.1 ml of 10 ⁶ cells / ml bacterial suspension is added and mixed well, then left at 30 ° C. for 4 hours. After standing, 0.1 ml of this mixed solution is collected and added to 0.9 ml of SCDLP medium and mixed well to reduce the effect of the antibacterial agent on the bacteria, and then the stock solution and physiological saline of this mixed solution are used. 0.1 ml each of the 10-fold and 100-fold diluted solutions is applied on an SCDLP agar medium, and Escherichia coli is cultured at 37 ° C. for 24 hours, and S. aureus is cultured at 37 ° C. for 48 hours. Count the number of colonies grown after incubation. The result of performing the same test with sterilized ion-exchanged water instead of the solution A was used as a blank, and the difference in the number of bacteria from the blank was scored according to the following criteria to evaluate antibacterial performance. In addition, the antibacterial test was performed 5 times for the same cleaning agent, and the average value of each evaluation score was used as the antibacterial evaluation.

* Antibacterial evaluation criteria 5 points: Bacterial count decreased to less than 1/1000 of blank 4 points: Bacterial count decreased to 1/1000 or more to less than 1/100 of blank 3 points: Bacterial count is 1/100 of blank Reduced to less than 1/10, 2 points: Bacterial count decreased to 1/10 or more to less than 1/1, 1 point: Bacterial count is the same as blank or increased from blank

Biguanide compound; polyhexamethylene biguanide hydrochloride (manufactured by Avicia Co., Ltd.) (average n mole number is 10)
Surfactant B1: The average addition mole number of ethylene oxide (hereinafter referred to as EO) is 10, the average addition mole number of propylene oxide (hereinafter referred to as PO) is 2, and the molar ratio thereof is EO / PO / EO = 7/2/3. Polyoxyethylene alkyl ether added to block type so that the alkyl group is a mixture of 12 and 14 carbon atoms (weight ratio is 7/3)
Surfactant B2: alkylpolyglucoside (Mydol 12, manufactured by Kao Corporation, a mixture of linear alkyl groups having 12 and 14 carbon atoms, sugar average condensation degree of 1.2 (condensation degree of 1 and 2 mixture) )
Surfactant B3: Dodecyldimethylamine oxide (Amphithol 20N, manufactured by Kao Corporation)
-Cationic surfactant; N-decyl-N, N-dimethyl-N-benzylammonium chloride-LAS; Sodium alkylbenzene sulfonate having 10 to 14 carbon atoms-ES; Polyoxyethylene lauryl having an EO average addition mole number of 2.0 Sodium ether sulfate and sodium polyacrylate; weight average molecular weight 8000
-Polyethylene glycol monophenyl ether: EO average addition mole number 3

Claims (3)

Polyoxyalkylene alkyl ether type surfactant having a biguanide compound (a) of 0.05% by mass or more and less than 1% by mass, having a hydrocarbon group having 8 to 18 carbon atoms and a polyoxyalkylene group having an average addition mole number of 5 to 20 Agent (b1), alkylglycoside surfactant (b2) having an alkyl group having 8 to 16 carbon atoms and an average degree of condensation of 1 to 2, and an amine oxide type having one hydrocarbon group having 8 to 18 carbon atoms 1% or more of surfactant (b) selected from surfactant (b3) is contained in an amount of 2% by mass or more and less than 50% by mass, and (a) component / (b) component = 1/20 to 1/500. A liquid detergent for clothing having a mass ratio of The liquid detergent for clothes according to claim 1, wherein the biguanide compound is a compound having a structure represented by the following general formula (1).

A method for washing clothing, comprising washing the liquid detergent for clothing according to claim 1 or 2 with water so that the concentration of the component (a) is 0.05 ppm to 5 ppm.