JP2006069919A - Germicidal disinfectant - Google Patents
Germicidal disinfectant Download PDFInfo
- Publication number
- JP2006069919A JP2006069919A JP2004252227A JP2004252227A JP2006069919A JP 2006069919 A JP2006069919 A JP 2006069919A JP 2004252227 A JP2004252227 A JP 2004252227A JP 2004252227 A JP2004252227 A JP 2004252227A JP 2006069919 A JP2006069919 A JP 2006069919A
- Authority
- JP
- Japan
- Prior art keywords
- disinfectant
- mass
- polyoxyethylene
- wet wiper
- fabric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000645 desinfectant Substances 0.000 title claims abstract description 74
- 230000002070 germicidal effect Effects 0.000 title abstract description 5
- 150000003839 salts Chemical class 0.000 claims abstract description 15
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims abstract description 13
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims abstract description 12
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 11
- 239000004744 fabric Substances 0.000 claims description 17
- 239000000835 fiber Substances 0.000 claims description 17
- 230000000844 anti-bacterial effect Effects 0.000 claims description 16
- ZKHQWZAMYRWXGA-UHFFFAOYSA-N Adenosine triphosphate Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ZKHQWZAMYRWXGA-UHFFFAOYSA-N 0.000 claims description 14
- 238000004020 luminiscence type Methods 0.000 claims description 10
- ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 claims description 6
- 239000004094 surface-active agent Substances 0.000 claims description 6
- 150000001298 alcohols Chemical class 0.000 claims description 5
- 239000002738 chelating agent Substances 0.000 claims description 5
- -1 alkyl dimethyl benzylammonium Chemical compound 0.000 abstract description 68
- 235000014113 dietary fatty acids Nutrition 0.000 description 21
- 239000000194 fatty acid Substances 0.000 description 21
- 229930195729 fatty acid Natural products 0.000 description 21
- 238000011156 evaluation Methods 0.000 description 18
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 13
- 239000008213 purified water Substances 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 239000002280 amphoteric surfactant Substances 0.000 description 11
- 239000003945 anionic surfactant Substances 0.000 description 10
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 10
- 230000001954 sterilising effect Effects 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 230000000052 comparative effect Effects 0.000 description 8
- 239000011734 sodium Substances 0.000 description 8
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 7
- 229960000686 benzalkonium chloride Drugs 0.000 description 7
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
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- 239000004745 nonwoven fabric Substances 0.000 description 7
- 229910052708 sodium Inorganic materials 0.000 description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
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- 206010040880 Skin irritation Diseases 0.000 description 6
- 125000005211 alkyl trimethyl ammonium group Chemical group 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
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- 230000036556 skin irritation Effects 0.000 description 6
- 231100000475 skin irritation Toxicity 0.000 description 6
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 5
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 5
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- 239000003240 coconut oil Substances 0.000 description 5
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- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 4
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 4
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- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- 239000000284 extract Substances 0.000 description 4
- 235000013372 meat Nutrition 0.000 description 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
- 239000003206 sterilizing agent Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 3
- 239000004166 Lanolin Substances 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 239000004147 Sorbitan trioleate Substances 0.000 description 3
- PRXRUNOAOLTIEF-ADSICKODSA-N Sorbitan trioleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC PRXRUNOAOLTIEF-ADSICKODSA-N 0.000 description 3
- 150000005215 alkyl ethers Chemical class 0.000 description 3
- 239000004359 castor oil Substances 0.000 description 3
- 235000019438 castor oil Nutrition 0.000 description 3
- 239000003093 cationic surfactant Substances 0.000 description 3
- 230000000249 desinfective effect Effects 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 3
- 229960002449 glycine Drugs 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 description 3
- 235000019388 lanolin Nutrition 0.000 description 3
- 229940039717 lanolin Drugs 0.000 description 3
- 239000002736 nonionic surfactant Substances 0.000 description 3
- 239000000123 paper Substances 0.000 description 3
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 239000002964 rayon Substances 0.000 description 3
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- 229960000391 sorbitan trioleate Drugs 0.000 description 3
- 238000004383 yellowing Methods 0.000 description 3
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 description 2
- ARXKVVRQIIOZGF-UHFFFAOYSA-N 1,2,4-butanetriol Chemical compound OCCC(O)CO ARXKVVRQIIOZGF-UHFFFAOYSA-N 0.000 description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 2
- GRVMJKAAXNELJW-UHFFFAOYSA-N 1-phenylpropan-1-amine;hydrochloride Chemical compound [Cl-].CCC([NH3+])C1=CC=CC=C1 GRVMJKAAXNELJW-UHFFFAOYSA-N 0.000 description 2
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 2
- WJYAJBDKANFOID-UHFFFAOYSA-N 2-(dodecylamino)propanoic acid Chemical class CCCCCCCCCCCCNC(C)C(O)=O WJYAJBDKANFOID-UHFFFAOYSA-N 0.000 description 2
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- MOMKYJPSVWEWPM-UHFFFAOYSA-N 4-(chloromethyl)-2-(4-methylphenyl)-1,3-thiazole Chemical compound C1=CC(C)=CC=C1C1=NC(CCl)=CS1 MOMKYJPSVWEWPM-UHFFFAOYSA-N 0.000 description 2
- CFKMVGJGLGKFKI-UHFFFAOYSA-N 4-chloro-m-cresol Chemical compound CC1=CC(O)=CC=C1Cl CFKMVGJGLGKFKI-UHFFFAOYSA-N 0.000 description 2
- XZIIFPSPUDAGJM-UHFFFAOYSA-N 6-chloro-2-n,2-n-diethylpyrimidine-2,4-diamine Chemical compound CCN(CC)C1=NC(N)=CC(Cl)=N1 XZIIFPSPUDAGJM-UHFFFAOYSA-N 0.000 description 2
- 239000005711 Benzoic acid Substances 0.000 description 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 2
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 2
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- 239000011487 hemp Substances 0.000 description 1
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- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
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Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Description
本発明は、アルキル基がラウリル基あるいはミリスチル基であるアルキルジメチルベンジルアンモニウムまたはその塩の１種または２種以上を９６質量％以上含む殺菌消毒剤及び殺菌消毒剤含有ウェットワイパーに関する。 The present invention relates to a disinfectant and a disinfectant-containing wet wiper containing 96% by mass or more of one or more of alkyldimethylbenzylammonium or a salt thereof whose alkyl group is a lauryl group or myristyl group.
従来より、塩化ベンザルコニウムが殺菌消毒、消臭、防黴を目的として医療分野、食品分野、化粧品分野、工業分野等で広く用いられており、高い効果も有しているため、一般的に使用されている。
通常、塩化ベンザルコニウムは第１４改正日本薬局方によれば式（１）で示され、ＲがＣ８Ｈ１７〜Ｃ１８Ｈ３７で主としてＣ１２Ｈ２５（ラウリル基）及びＣ１４Ｈ２９（ミリスチル基）からなると定義されているが、その割合については特に規定されていない。また、不純物についても規定されていない。
また、ウェットティッシュのような布帛などに色々な含浸液を含浸させたウェットワイパーにも塩化ベンゼルコニウムは製品の防菌防黴の目的のために使用されている。
〔Ｃ６Ｈ５ＣＨ２Ｎ（ＣＨ３）２Ｒ〕Ｃｌ・・・・・（１）
Conventionally, benzalkonium chloride has been widely used in the medical field, food field, cosmetics field, industrial field, etc. for the purpose of sterilization, deodorization, and antifungal, and it has a high effect. in use.
Usually, benzalkonium chloride is represented by the formula (1) according to the 14th revised Japanese Pharmacopoeia, R is C 8 H 17 to C 18 H 37 , and mainly C 12 H 25 (lauryl group) and C 14 H 29. Although it is defined as consisting of (myristyl group), the ratio is not particularly specified. Also, impurities are not specified.
Also, benzalkonium chloride is used for antibacterial and antibacterial purposes of products in wet wipers obtained by impregnating various impregnating liquids with a cloth such as a wet tissue.
[C 6 H 5 CH 2 N (CH 3 ) 2 R] Cl (1)
従来、広く一般的に使用されている殺菌消毒剤である塩化ベンザルコニウムは、匂いがする、経口毒性や皮膚刺激が高いという欠点も有している。
また、布帛などに塩化ベンザルコニウムを含浸させたウェットワイパーがボトルやピロー包装、ボックスの中に装填された一般品は、部分的に乾燥されると黄色くなる現象が起きる問題もある（特許文献１〜３参照）。
In addition, a general product in which a wet wiper impregnated with benzalkonium chloride in a fabric or the like is loaded in a bottle, pillow packaging, or box has a problem that yellowing occurs when it is partially dried (Patent Literature). 1-3).
本発明は匂いや皮膚刺激を低減した殺菌消毒剤及び、その殺菌消毒剤を含有するウェットワイパーを提供することを目的とする。 An object of the present invention is to provide a disinfectant with reduced odor and skin irritation and a wet wiper containing the disinfectant.
本発明者は、上記課題を解決するために鋭意研究を重ねた結果、下記の式（２）で表せるアルキル基がラウリル基あるいはミリスチル基であるアルキルジメチルベンジルアンモニウムまたはその塩の１種または２種以上を９６質量％以上含む殺菌消毒剤が、その目的に適合しうることを見出し、この知見に基づいて本発明をなすに至った。
〔Ｃ６Ｈ５ＣＨ２Ｎ（ＣＨ３）２Ｒ〕Ｘ・・・・・（２）
（式中、Ｒはラウリル基あるいはミリスチル基を表し、Ｘはハロゲンイオンを表す）
As a result of intensive studies to solve the above problems, the present inventor has found that one or two of alkyldimethylbenzylammonium or a salt thereof in which the alkyl group represented by the following formula (2) is a lauryl group or a myristyl group. The present inventors have found that a sterilizing and disinfecting agent containing 96% by mass or more of the above can meet the purpose, and have made the present invention based on this finding.
[C 6 H 5 CH 2 N (CH 3 ) 2 R] X (2)
(In the formula, R represents a lauryl group or a myristyl group, and X represents a halogen ion)
すなわち、本発明は下記に示す通りである。
１．アルキル基がラウリル基あるいはミリスチル基であるアルキルジメチルベンジルアンモニウムまたはその塩の１種または２種以上を９６質量％以上含むことを特徴とする殺菌消毒剤。
２.上記１．記載の殺菌消毒剤を０．０００１〜３０質量％含むことを特徴とする殺菌消毒剤。
３．さらに、界面活性剤、低級アルコール、殺菌剤およびキレート剤から選ばれる１種または２種以上を含むことを特徴とする１．または２．記載の殺菌消毒剤。
４．上記１．〜３．のいずれかに記載の殺菌消毒剤で対象面を拭き取った直後、アデノシン３リン酸測定器で測定した相対発光量が拭き取る前の相対発光量に比べ５０％以下に減少することを特徴とする殺菌消毒剤。
５．上記１．〜４．のいずれかに記載の殺菌消毒剤で対象面を拭き取り、２４時間後にアデノシン３リン酸測定器で測定した相対発光量が拭き取る前の相対発光量に比べ５０％以下であることを特徴とする殺菌消毒剤。
６.上記１．〜５．のいずれかに記載の殺菌消毒剤を布帛に含浸させてなる殺菌消毒剤含有ウェットワイパー。
７.布帛１質量部に対し１．〜５．のいずれかに記載の殺菌消毒剤を０．５質量部以上含むことを特徴とする殺菌消毒剤含有ウェットワイパー。
８.布帛が親水性繊維を２質量％以上含むことを特徴とする６．〜７．のいずれかに記載の殺菌消毒剤含有ウェットワイパー。
That is, the present invention is as follows.
1. A disinfectant containing at least 96% by mass of one or more of alkyldimethylbenzylammonium or a salt thereof whose alkyl group is a lauryl group or myristyl group.
2. Above 1. A sterilizing and disinfecting agent comprising 0.0001 to 30% by mass of the sterilizing and disinfecting agent described.
3. Furthermore, it contains one or more selected from surfactants, lower alcohols, bactericides and chelating agents. Or 2. The disinfectant described.
4). Above 1. ~ 3. Immediately after wiping the target surface with the disinfectant according to any one of the above, the relative luminescence measured by the adenosine triphosphate measuring instrument is reduced to 50% or less compared to the relative luminescence before wiping. disinfectant.
5. Above 1. ~ 4. The target surface is wiped off with the disinfectant according to any one of the above, and the relative luminescence measured with an adenosine triphosphate measuring device after 24 hours is 50% or less compared to the relative luminescence before wiping. disinfectant.
6. Above 1. ~ 5. A disinfectant-containing wet wiper obtained by impregnating a fabric with the disinfectant according to any one of the above.
7. 1. 1 part by weight of fabric ~ 5. A disinfectant-containing wet wiper, comprising 0.5 part by mass or more of the disinfectant described in any of the above.
8. The fabric contains 2% by mass or more of hydrophilic fibers. ~ 7. A wet wiper containing a disinfectant according to any one of the above.
本発明のアルキル基がラウリル基あるいはミリスチル基であるアルキルジメチルベンジルアンモニウムまたはその塩の１種または２種以上を９６質量％以上含む殺菌消毒剤は匂い及び皮膚刺激低減の効果を有する。また、布帛などに本発明のアルキル基がラウリル基あるいはミリスチル基であるアルキルジメチルベンジルアンモニウムまたはその塩を１種または２種以上を９６質量％以上含む殺菌消毒剤を含浸させたウェットワイパーがボトルやピロー包装、ボックスの中に装填された一般品は、部分的に乾燥しても黄変するなどの現象が生じない効果を有する。 The disinfectant containing at least 96% by mass of one or more of alkyldimethylbenzylammonium or a salt thereof in which the alkyl group of the present invention is a lauryl group or a myristyl group has an effect of reducing odor and skin irritation. Further, a wet wiper in which a cloth or the like is impregnated with a disinfectant containing at least 96% by mass of one or more alkyldimethylbenzylammonium or a salt thereof in which the alkyl group of the present invention is a lauryl group or a myristyl group is used as a bottle, A general product loaded in a pillow package or box has an effect that a phenomenon such as yellowing does not occur even when partially dried.
本発明について、以下具体的に説明する。
本発明のアルキルジメチルベンジルアンモニウムまたはその塩は特に限定されるものではなくＦ、Ｃｌ、Ｂｒ、Ｉ、Ａｔのハロゲンイオンであれば何でも良い。特にＣｌ、Ｂｒ、Ｉが好ましい。
アルキル基がラウリル基あるいはミリスチル基であるアルキルジメチルベンジルアンモニウムまたはその塩の１種または２種以上を９６質量％以上含む殺菌消毒剤が０．０００１質量％以上であれば十分に殺菌性能が得られ、３０質量％以下であれば皮膚刺激を押さえることができる。つまり０．０００１〜３０質量％含まれていれば、特にその効果は顕著である。更に好ましくは殺菌消毒剤が０．５〜１０質量％である。
The present invention will be specifically described below.
The alkyldimethylbenzylammonium salt or salt thereof of the present invention is not particularly limited, and any halogen ion of F, Cl, Br, I, At may be used. In particular, Cl, Br, and I are preferable.
If the disinfectant containing at least 96% by mass of one or more of alkyldimethylbenzylammonium or its salt whose alkyl group is a lauryl group or myristyl group is at least 0.0001% by mass, sufficient disinfection performance can be obtained. If it is 30% by mass or less, skin irritation can be suppressed. That is, the effect is particularly remarkable when it is contained in an amount of 0.0001 to 30% by mass. More preferably, the disinfectant is 0.5 to 10% by mass.
アルキル基がラウリル基あるいはミリスチル基であるアルキルジメチルベンジルアンモニウムまたはその塩の１種または２種以上を９６質量％以上含む殺菌消毒剤に更に界面活性剤、低級アルコール、殺菌剤およびキレート剤から選ばれる１種または２種以上を組み合わせて殺菌性能や洗浄機能を向上させたりすることができる。 The disinfectant containing at least 96% by mass of one or more of alkyldimethylbenzylammonium or its salt whose alkyl group is a lauryl group or myristyl group is selected from surfactants, lower alcohols, disinfectants and chelating agents. One type or two or more types can be combined to improve sterilization performance and cleaning function.
本発明に使用できる界面活性剤としては界面活性能を示すものであれば何でも良い。例えばノニオン系界面活性剤、両性界面活性剤、カチオン系界面活性剤、アニオン系界面活性剤等が挙げられるが、特に限定されるものではない。
ノニオン系界面活性剤の具体例としてはレシチン、高分子乳化剤、グリセリン脂肪酸エステル、親油型モノステアリン酸グリセリン等のグリセリン脂肪酸エステル類、モノオレイン酸ポリグリセリル、ペンタオレイン酸ポリグリセリル、デカオレイン酸ポリグリセリル等のポリグリセリン脂肪酸エステル類、モノステアリン酸ポリオキシエチレングリセリン等のポリオキシエチレングリセリン脂肪酸エステル類、モノラウリン酸ソルビタン、モノオレイン酸ソルビタン、トリオレイン酸ソルビタン等のソルビタン脂肪酸エステル類、モノステアリン酸ポリオキシエチレンソルビタン、トリオレイン酸ポリオキシエチレンソルビタン等のポリオキシエチレンソルビタン脂肪酸エステル類、モノラウリン酸ポリオキシエチレンソルビット、テトラオレイン酸ポリオキシエチレンソルビット等のポリオキシエチレンソルビット脂肪酸エステル類、ポリオキシエチレンラノリン、ポリオキシエチレンソルビットミツロウ等のポリオキシエチレンラノリン・ラノリンアルコール・ミツロウ誘導体、ポリオキシエチレンヒマシ油、ポリオキシエチレン硬化ヒマシ油等のポリオキシエチレンヒマシ油・硬化ヒマシ油類、ポリオキシエチレンコレスタノールエーテル等のポリオキシエチレンステロール・水素添加ステロール類、モノステアリン酸エチレングリコール、モノオレイン酸ポリエチレングリコール等のポリエチレングリコール脂肪酸エステル類、ポリオキシエチレンラウリルエーテル、ポリオキシエチレンセチルエーテル、ポリオキシエチレンベヘニルエーテル等のポリオキシエチレンアルキルエーテル類、ポリオキシエチレンポリオキシプロピレンセチルエーテル、ポリオキシエチレンポリオキシプロピレンデシルテトラデシルエーテル等のポリオキシエチレンポリオキシプロピレンアルキルエーテル類、ポリオキシエチレンノニルフェニルエーテル等のポリオキシエチレンアルキルフェニルエーテル類、ポリオキシエチレンステアリン酸アミド等のポリオキシエチレンアルキルアミン・脂肪酸アミド類、ショ糖脂肪酸エステル、アルキルグルコシド等を挙げる事ができる。この中でも特に好ましいノニオン系界面活性剤としてレシチン、グリセリン脂肪酸エステル、親油型モノステアリン酸グリセリン等のグリセリン脂肪酸エステル類、モノオレイン酸ポリグリセリル、ペンタオレイン酸ポリグリセリル、デカオレイン酸ポリグリセリル等のポリグリセリン脂肪酸エステル類、モノラウリン酸ソルビタン、モノオレイン酸ソルビタン、トリオレイン酸ソルビタン等のソルビタン脂肪酸エステル類、ショ糖脂肪酸エステル、アルキルグルコシド等を挙げる事ができる。
As the surfactant that can be used in the present invention, any surfactant can be used as long as it exhibits surface activity. Examples include nonionic surfactants, amphoteric surfactants, cationic surfactants, anionic surfactants, and the like, but are not particularly limited.
Specific examples of nonionic surfactants include lecithin, polymer emulsifiers, glycerin fatty acid esters, glycerin fatty acid esters such as lipophilic glyceryl monostearate, polyglyceryl monooleate, polyglyceryl pentaoleate, and polyglyceryl dekaoleate. Glycerin fatty acid esters, polyoxyethylene glycerol fatty acid esters such as polyoxyethylene glyceryl monostearate, sorbitan fatty acid esters such as sorbitan monolaurate, sorbitan monooleate, sorbitan trioleate, polyoxyethylene sorbitan monostearate, Polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan trioleate, polyoxyethylene sorbite monolaurate, tetra Polyoxyethylene sorbite fatty acid esters such as polyoxyethylene sorbate oleate, polyoxyethylene lanolin, lanolin alcohol, beeswax derivatives such as polyoxyethylene lanolin, polyoxyethylene sorbit beeswax, polyoxyethylene castor oil, polyoxyethylene hardened castor Polyoxyethylene castor oil and hydrogenated castor oil such as oil, polyoxyethylene sterol and hydrogenated sterol such as polyoxyethylene cholestanol ether, polyethylene glycol fatty acid esters such as ethylene glycol monostearate and polyethylene glycol monooleate , Polyoxyethylene lauryl ether, polyoxyethylene cetyl ether, polyoxyethylene behenyl ether, etc. Kill ethers, polyoxyethylene polyoxypropylene cetyl ether, polyoxyethylene polyoxypropylene decyl tetradecyl ether and other polyoxyethylene polyoxypropylene alkyl ethers, polyoxyethylene nonylphenyl ether and other polyoxyethylene alkylphenyl ethers And polyoxyethylene alkylamine / fatty acid amides such as polyoxyethylene stearamide, sucrose fatty acid ester, alkyl glucoside and the like. Among these, particularly preferred nonionic surfactants include glycerin fatty acid esters such as lecithin, glycerin fatty acid ester, lipophilic glyceryl monostearate, polyglyceryl fatty acid esters such as polyglyceryl monooleate, polyglyceryl pentaoleate, and polyglyceryl dekaoleate. And sorbitan fatty acid esters such as sorbitan monolaurate, sorbitan monooleate and sorbitan trioleate, sucrose fatty acid esters, alkyl glucosides and the like.
両性界面活性剤の具体例としてはラウリルジアミノエチルグリシンナトリウム、塩化アルキルジアミノエチルグリシン、ヤシ油脂肪酸アシル−Ｎ−カルボキシエトキシエチル−Ｎ−カルボキシエチルエチレンジアミン２ナトリウム等のグリシン型両性界面活性剤、ヤシ油脂肪酸アシル−Ｎ−ヒドロキシエチルエチレンジアミンナトリウム等のラウリルアミノプロピオン酸塩等のアミノプロピオン酸型両性両性界面活性剤、アルキルジメチルアミノ酢酸ベタイン、アルキルジメチルベタインナトリウム、ヤシ油脂肪酸アミドプロピルベタインラウリン酸アミドプロピル酢酸ベタイン等のアミノ酢酸ベタイン型両性界面活性剤、ラウリルヒドロキシスルホベタイン等のスルホベタイン型両性界面活性剤等が挙げられる。この中でも特に好ましい両性界面活性剤としてラウリルジアミノエチルグリシンナトリウム、塩化アルキルジアミノエチルグリシン、ヤシ油脂肪酸アシル−Ｎ−カルボキシエトキシエチル−Ｎ−カルボキシエチルエチレンジアミン２ナトリウム等のグリシン型両性界面活性剤、ヤシ油脂肪酸アシル−Ｎ−ヒドロキシエチルエチレンジアミンナトリウム等のラウリルアミノプロピオン酸塩等のアミノプロピオン酸型両性両性界面活性剤、アルキルジメチルアミノ酢酸ベタイン、アルキルジメチルベタインナトリウム、ヤシ油脂肪酸アミドプロピルベタインラウリン酸アミドプロピル酢酸ベタイン等のアミノ酢酸ベタイン型両性界面活性剤等を挙げる事ができる。 Specific examples of amphoteric surfactants include lauryl diaminoethyl glycine sodium, alkyl diaminoethyl glycine chloride, coconut oil fatty acid acyl-N-carboxyethoxyethyl-N-carboxyethyl ethylenediamine disodium glycine type amphoteric surfactant, coconut oil Aminoampionic amphoteric surfactants such as fatty acid acyl-N-hydroxyethylethylenediamine sodium and other laurylaminopropionates, alkyldimethylaminoacetic acid betaines, sodium alkyldimethylbetaine, coconut oil fatty acid amidopropyl betaine lauric acid amide propylacetic acid Examples thereof include aminoacetic acid betaine type amphoteric surfactants such as betaine and sulfobetaine type amphoteric surfactants such as lauryl hydroxysulfobetaine. Of these, particularly preferred amphoteric surfactants are glycine-type amphoteric surfactants such as sodium lauryldiaminoethylglycine, alkyldiaminoethylglycine chloride, coconut oil fatty acid acyl-N-carboxyethoxyethyl-N-carboxyethylethylenediamine disodium, and palm oil. Aminoampionic amphoteric surfactants such as fatty acid acyl-N-hydroxyethylethylenediamine sodium and other laurylaminopropionates, alkyldimethylaminoacetic acid betaines, sodium alkyldimethylbetaine, coconut oil fatty acid amidopropyl betaine lauric acid amide propylacetic acid Examples include aminoacetic acid betaine-type amphoteric surfactants such as betaine.
カチオン系界面活性剤の具体例としてはステアリン酸ジエチルアミノエチルアミド等の脂肪族アミン塩、塩化アルキルトリメチルアンモニウム、臭化アルキルトリメチルアンモニウム、アルキルトリメチルアンモニウムサッカリン、塩化ジポリオキシエチレンアルキルメチルアンモニウム等のアルキル４級アンモニウム、塩化アルキルジメチルベンジルアンモニウム、塩化ラウリルピジニウム、塩化アルキルジメチル（エチルベンジル）アンモニウム等の環式４級アンモニウム塩等が挙げられる。この中でも特に好ましいカチオン系界面活性剤として塩化アルキルトリメチルアンモニウム、臭化アルキルトリメチルアンモニウム、アルキルトリメチルアンモニウムサッカリン、塩化ジポリオキシエチレンアルキルメチルアンモニウム等のアルキル４級アンモニウム、塩化アルキルジメチルベンジルアンモニウム、塩化ラウリルピジニウム、塩化アルキルジメチル（エチルベンジル）アンモニウム等の環式４級アンモニウム塩等を挙げる事ができる。 Specific examples of the cationic surfactant include aliphatic amine salts such as diethylaminoethyl stearate, alkyl 4 such as alkyltrimethylammonium chloride, alkyltrimethylammonium bromide, alkyltrimethylammonium saccharin, and dipolyoxyethylene alkylmethylammonium chloride. And cyclic quaternary ammonium salts such as quaternary ammonium, alkyldimethylbenzylammonium chloride, laurylpyidinium chloride, and alkyldimethyl (ethylbenzyl) ammonium chloride. Among these, particularly preferred cationic surfactants are alkyl quaternary ammonium such as alkyl trimethyl ammonium chloride, alkyl trimethyl ammonium bromide, alkyl trimethyl ammonium saccharin, dipolyoxyethylene alkyl methyl ammonium chloride, alkyl dimethyl benzyl ammonium chloride, lauryl pyridine. And cyclic quaternary ammonium salts such as ammonium and alkyldimethyl (ethylbenzyl) ammonium chloride.
アニオン系界面活性剤としはポリオキシエチレンアルキルエーテル酢酸及びその塩等のアルキルエーテルカルボン酸型アニオン系界面活性剤、Ｎ−アシルサルコシン塩、Ｎ−アシルグルタミン酸塩、Ｎ−アシルアルキルタウリン塩等のＮ−アシル有機酸塩型アニオン系界面活性剤、α―オレフィンスルホン酸塩、アルキルスルホコハク酸塩等のスルホン酸塩型アニオン系界面活性剤、アルキル硫酸エステル塩等の硫酸塩型アニオン系界面活性剤、ポリオキシエチレンアルキルエーテルリン酸塩等のリン酸塩型アニオン系界面活性剤、ポリオキシエチレンラウリルエーテル硫酸ナトリウム等のポリオキシエチレンアルキルエーテル硫酸塩類等が挙げられる。この中でも特に好ましいアニオン系界面活性剤はとしてポリオキシエチレンアルキルエーテル酢酸及びその塩等のアルキルエーテルカルボン酸型アニオン系界面活性剤、Ｎ−アシルグルタミン酸塩、Ｎ−アシルアルキルタウリン塩等のＮ−アシル有機酸塩型アニオン系界面活性剤、ポリオキシエチレンラウリルエーテル硫酸ナトリウム等のポリオキシエチレンアルキルエーテル硫酸塩類等を挙げる事ができる。
これらの界面活性剤は１種単独あるいは２種以上と組み合わせて用いる事ができる。
Anionic surfactants include alkyl ether carboxylic acid type anionic surfactants such as polyoxyethylene alkyl ether acetic acid and its salts, N-acyl sarcosine salts, N-acyl glutamates, N-acyl alkyl taurine salts, etc. -Acyl organic acid salt type anionic surfactant, α-olefin sulfonate, sulfonate type anionic surfactant such as alkyl sulfosuccinate, sulfate type anionic surfactant such as alkyl sulfate ester salt, Examples thereof include phosphate anionic surfactants such as polyoxyethylene alkyl ether phosphates, and polyoxyethylene alkyl ether sulfates such as sodium polyoxyethylene lauryl ether sulfate. Among these, particularly preferred anionic surfactants include alkyl ether carboxylic acid type anionic surfactants such as polyoxyethylene alkyl ether acetic acid and its salts, N-acyl such as N-acyl glutamate and N-acyl alkyl taurate. Examples thereof include organic acid salt type anionic surfactants and polyoxyethylene alkyl ether sulfates such as sodium polyoxyethylene lauryl ether sulfate.
These surfactants can be used alone or in combination of two or more.
本発明に使用できる低級アルコールとしては、炭素数１〜４の水溶性アルコール類が好ましく、具体的にはメタノール、エタノール、プロパノール、イソプロピルアルコール、２−メトキシエタノール、２−エトキシエタノール、２−メトキシプロパノール、２−メトキシイソプロパノール等のモノオール類やエチレングリコール、プロピレングリコール、１，３―プロパンジオール、２，３−ブタンジオール、１，２−ブタンジオール、１，３−ブタンジオール、１，４−ブタンジオール、２−メチルー１、２−プロパンジオール、ジエチレングリコール、１，４−ブチンジオール等のジオール類やグリセリン、１，２，４−ブタントリオール、エリスリトール等のポリオールが挙げられる。この中でも特に好ましい低級アルコールとしてエタノール、プロパノール、イソプロパノール、エチレングリコール、プロピレングリコール、１，３−ブタンジオール、ジエチレングリコール、グリセリン等を挙げる事ができる。
これらの低級アルコールは１種単独あるいは２種以上と組み合わせて用いる事ができる。
The lower alcohol that can be used in the present invention is preferably a water-soluble alcohol having 1 to 4 carbon atoms, specifically, methanol, ethanol, propanol, isopropyl alcohol, 2-methoxyethanol, 2-ethoxyethanol, 2-methoxypropanol. Monools such as 2-methoxyisopropanol, ethylene glycol, propylene glycol, 1,3-propanediol, 2,3-butanediol, 1,2-butanediol, 1,3-butanediol, 1,4-butane Examples include diols such as diol, 2-methyl-1,2-propanediol, diethylene glycol, and 1,4-butynediol, and polyols such as glycerin, 1,2,4-butanetriol, and erythritol. Among these, particularly preferred lower alcohols include ethanol, propanol, isopropanol, ethylene glycol, propylene glycol, 1,3-butanediol, diethylene glycol, glycerin and the like.
These lower alcohols can be used alone or in combination of two or more.
本発明に使用できる防腐剤としては安息香酸、安息香酸ナトリウム、ウンデレン酸、サリチル酸、ソルビン酸、ソルビン酸カリウム、デヒドロ酢酸、デヒドロ酢酸ナトリウム、パラオキシ安息香酸エステル類及びその塩等の有機酸及びその誘導体、イソプロピルメチルフェノール、グルコン酸クロルヘキシジン、クレゾール、クロロチモール、クロロフェネシン、クロロクレゾール、ジクロロキシレノール、ジクロロベンジルアルコール、チオビスクロロフェノール、チモール、トリクロロカルバニリド、トリクロロヒドロキシジフェニルエーテル、ナトリウムフェノキシド、パラクロロフェノール、ハロカルバン、フェニルエチルアルコール、フェニルフェノール、フェニルフェノールナトリウム、、フェノキシエタノール、フェノール、フェキサクロロフェン、ベンジルアルコール等のフェノール類、塩化ステアリルジメチルベンジルアルコール、塩化ステアリルトリメチルアンモニウム、塩化セチルトリメチルアンモニウム、塩化ベンザルコニウム、塩化セチルピリジウム、塩化ベンゼトニウム、塩化メチルベンゼトニウム、塩化ラウリルトリメチルアンモニウム、塩化ラウリルピリジニウム、塩化ラウロイルコラミノホルミルメチルピリジニウム、臭化アルキルイソキノリニウム、臭化セチルトリメチルアンモニウム、臭化ドミフェン、臭化ラウリルトリメチルアンモニウム、セチルトリメチルアンモニウムサッカリン等の４級アンモニウム塩、塩酸アルキルジアミノエチルグリシン等の両性界面活性剤、プラトニン、ピオニン、ルミネキス、感光素ＮＫ１４３等の感光素、茶エキス、ヒノキキチオール、リンゴエキス、ポリリジン等の抗菌活性を持つ植物抽出液、その他グルタラール、クロラミンＴ、クロルヘキシジン、ジイセチオン酸ジプロモプロパミジン、ジンクピリチオン、トリクロサン、ピリチオンＮａ、フルフラール、クロラミンＴ等が挙げられる。この中でも特に好ましい防腐剤として安息香酸及びその塩、サリチル酸、ソルビン酸、ソルビン酸カリウム、デヒドロ酢酸、デヒドロ酢酸ナトリウム、パラオキシ安息香酸エステル類、塩化セチルピリジウム、塩化ステアリルジメチルベンジルアンモニウム、茶エキス、ヒノキキチオール、リンゴエキス、ポリリジン、トリクロサン等を挙げる事ができる。
これら防腐剤は１種単独あるいは２種以上と組み合わせて用いる事ができる。
Examples of preservatives that can be used in the present invention include organic acids such as benzoic acid, sodium benzoate, undelenic acid, salicylic acid, sorbic acid, potassium sorbate, dehydroacetic acid, sodium dehydroacetate, paraoxybenzoic acid esters and salts thereof, and derivatives thereof. , Isopropylmethylphenol, chlorhexidine gluconate, cresol, chlorothymol, chlorophenesin, chlorocresol, dichloroxylenol, dichlorobenzyl alcohol, thiobischlorophenol, thymol, trichlorocarbanilide, trichlorohydroxydiphenyl ether, sodium phenoxide, parachlorophenol , Halocarban, phenylethyl alcohol, phenylphenol, sodium phenylphenol, phenoxyethanol, phenol, Exachlorophene, phenols such as benzyl alcohol, stearyl dimethyl benzyl alcohol, stearyl trimethyl ammonium chloride, cetyl trimethyl ammonium chloride, benzalkonium chloride, cetyl pyridinium chloride, benzethonium chloride, methyl benzethonium chloride, lauryl trimethyl ammonium chloride, Quaternary ammonium salts such as laurylpyridinium chloride, lauroylcoraminoformylmethylpyridinium chloride, alkylisoquinolinium bromide, cetyltrimethylammonium bromide, domifene, lauryltrimethylammonium bromide, cetyltrimethylammonium bromide, alkyldiamino hydrochloride Amphoteric surfactants such as ethylglycine, Platonin, Pionine, Luminekis, Photosensitizers such as Photosensitizer NK143 Plant extracts with antibacterial activity such as tea extract, hinokitiol, apple extract, polylysine, etc., glutaral, chloramine T, chlorhexidine, diisemopropamidine diisethionate, zinc pyrithione, triclosan, pyrithione Na, furfural, chloramine T, etc. It is done. Of these, benzoic acid and its salts, salicylic acid, sorbic acid, potassium sorbate, dehydroacetic acid, sodium dehydroacetate, paraoxybenzoic acid esters, cetylpyridium chloride, stearyldimethylbenzylammonium chloride, tea extract, cypress Examples include chithiol, apple extract, polylysine, and triclosan.
These preservatives can be used alone or in combination of two or more.
本発明に使用できるキレート剤は、金属捕獲作用があれば何でも良いが、コンプレキサン、アラニン、エチレンジアミンヒドロキシエチル３酢酸３ナトリウム、エデト酸、エデト酸２ナトリウム、エデト酸２ナトリウムカルシウム、エデト酸３ナトリウム、エデト酸４ナトリウム、クエン酸ナトリウム、クエン酸、グルコン酸、酒石酸、フィチン酸、ポリリン酸ナトリウム、メタリン酸ナトリウム等が好ましい。この中でも特に好ましいキレート剤として、アラニン、エデト酸２ナトリウム、エデト酸２ナトリウムカルシウム、クエン酸ナトリウム、クエン酸、グルコン酸、酒石酸、ポリリン酸ナトリウム、メタリン酸ナトリウム等を挙げる事ができる。これら防腐剤は１種単独あるいは２種以上と組み合わせて用いる事ができる。 The chelating agent that can be used in the present invention is not particularly limited as long as it has a metal-capturing action, but is complexane, alanine, ethylenediamine hydroxyethyl triacetate trisodium, edetic acid, edetate disodium, edetate disodium calcium, edetate trisodium. Edetic acid 4 sodium, sodium citrate, citric acid, gluconic acid, tartaric acid, phytic acid, sodium polyphosphate, sodium metaphosphate and the like are preferable. Among these, particularly preferable chelating agents include alanine, disodium edetate, disodium calcium edetate, sodium citrate, citric acid, gluconic acid, tartaric acid, sodium polyphosphate, sodium metaphosphate, and the like. These preservatives can be used alone or in combination of two or more.
また、その他の成分として着色剤や香料、安定剤等を本発明の殺菌消毒剤に添加しても差し支えない。
本発明の殺菌消毒剤は固体表面に付着している汚れを除去する性能を有している。アデノシン３リン酸測定器（以下ＡＴＰ測定器と略す）は動物（食肉等）、植物（野菜等）、微生物（細菌）などには必ずアデノシン３リン酸（以下ＡＴＰと略す）が含まれており、このＡＴＰを測定することにより固体表面に残された汚れ（食肉、野菜、微生物）を定量的に測定できる装置である。また、このＡＴＰを抽出して蛍の酵素を含んだ発光試薬を添加するとＡＴＰの量に応じて光の強さが変化し、その強さを数値化したものが相対発光量（ＲＬＵ：Ｒｅｌａｔｉｖｅ Ｌｉｇｈｔ Ｕｎｉｔ）である。そこで、その洗浄効果をＡＴＰ測定器（ＢＩＯＴＲＡＣＥ社製：ＵＮＩ―ＬＩＴＥ ＮＧ）を用いて測定を行った。本発明の殺菌消毒剤を対象物に接触させ拭き取った後、その値を測定すると拭き取る前の値に比べると相対発光量（ＲＬＵ）が５０％以下であり、２４時間後にもう一度測定しても相対発光量は同様に５０％以下と効果を持続することができる。
In addition, colorants, fragrances, stabilizers and the like may be added to the disinfectant of the present invention as other components.
The disinfectant of the present invention has the ability to remove dirt adhering to the solid surface. Adenosine triphosphate measuring device (hereinafter abbreviated as ATP measuring device) always contains adenosine triphosphate (hereinafter abbreviated as ATP) in animals (meat, etc.), plants (vegetables, etc.) and microorganisms (bacteria). This is an apparatus capable of quantitatively measuring dirt (meat, vegetables, microorganisms) left on the solid surface by measuring this ATP. Further, when this ATP is extracted and a luminescent reagent containing a firefly enzyme is added, the intensity of light changes according to the amount of ATP, and the intensity is quantified as a relative luminescence (RLU: Relative Light). Unit). Therefore, the cleaning effect was measured using an ATP measuring device (manufactured by BIOTRACE: UNI-LITE NG). After wiping the sterilizing disinfectant of the present invention in contact with the object, the relative luminescence (RLU) is 50% or less compared to the value before wiping when measured, and even if measured again after 24 hours Similarly, the light emission amount can be maintained at 50% or less.
次に、本発明の殺菌消毒剤を布帛等に含浸させる事で殺菌消毒剤含有ウェットワイパーとすることができる。殺菌消毒剤含有ウェットワイパーに用いることができる布帛としては特に限定されるものでないが例えば、脱脂綿、紙、コットン、麻、パルプ、絹、リネン等の天然繊維、コットンリンター、ビスコースレーヨン、銅アンモニアレーヨン、溶剤紡糸レーヨン等の再生繊維、ナイロン（ポリアミド系繊維）、ポリエステル（ポリエステル系繊維）、アクリル（ポリアクリロニトリル系繊維）、ビニロン（ポリビニルアルコール系繊維）、ポリプロピレン（ポリプロピレン系繊維）、ビニリデン（ポリ塩化ビニリデン系繊維）、ポリウレタン（ポリウレタン系繊維）、ポリエチレン等の合成繊維を単独または混合物として使用できる。これらの中でも特に公定水分率が１％以上の親水性繊維を２％以上含む布帛が望ましく、それを用いることで本発明の殺菌消毒剤を布帛に充分に含浸させることができ、その効果が十分に得られる。 Next, a wet wiper containing a bactericidal disinfectant can be obtained by impregnating a cloth or the like with the bactericidal disinfectant of the present invention. The fabric that can be used for the disinfectant-containing wet wiper is not particularly limited. For example, natural fibers such as absorbent cotton, paper, cotton, hemp, pulp, silk, linen, cotton linter, viscose rayon, copper ammonia Recycled fibers such as rayon and solvent-spun rayon, nylon (polyamide fiber), polyester (polyester fiber), acrylic (polyacrylonitrile fiber), vinylon (polyvinyl alcohol fiber), polypropylene (polypropylene fiber), vinylidene (poly) Synthetic fibers such as vinylidene chloride fiber), polyurethane (polyurethane fiber), and polyethylene can be used alone or as a mixture. Among these, a fabric containing 2% or more of hydrophilic fibers having an official moisture content of 1% or more is particularly desirable. By using this, the disinfectant of the present invention can be sufficiently impregnated into the fabric, and the effect is sufficient. Is obtained.
これらの繊維を用いた布帛の形態は、紙、不織布、布などとすることができ、またその製造方法としては、公知の紙、不織布、布の製造方法であれば特に限定されないが、不織布は簡便性やコスト等を考慮すればとくに好ましい。
繊維シートの目付量は薄すぎても厚すぎても使用しにくいため１０〜１２０ｇ／ｍ2 で使用することが好ましく、更には１５〜８０ｇ／ｍ2で使用することが好ましい。
The form of the fabric using these fibers can be paper, non-woven fabric, cloth, and the like, and the production method is not particularly limited as long as it is a known paper, non-woven fabric, fabric production method. This is particularly preferable in view of simplicity and cost.
Basis weight of the fiber sheet is preferably used in 10~120g / m 2 for difficult to use or too thick or too thin, furthermore, it is preferably used in 15 to 80 g / m 2.
本発明の殺菌消毒剤含有ウェットワイパーは上記記載の殺菌消毒剤を上記記載の布帛に含浸したものであるが、ウェットワイパー中のこれらワイパー用組成液の総量が布帛質量１部に対して０．５部以上であれば殺菌効果が発揮され、拭き残りも少なく更には１〜５部含浸させることが好ましい。
本発明の殺菌消毒剤含有ウェットワイパーは各種表面の清浄、殺菌、抗菌等、例えば食品工場のベルトコンベヤや作業台、ステンレスバッドやボウル等の作業用具、冷蔵庫や料理を作るときに使用する道具、玩具、便座、窓ガラス、車両の窓ガラス、洗面台、人体の清浄、殺菌消毒等に好適に用いられる。
The disinfectant-containing wet wiper of the present invention is obtained by impregnating the above disinfectant with the disinfectant described above. The total amount of these wiper composition liquids in the wet wiper is 0. If it is 5 parts or more, the bactericidal effect is exhibited, and it is preferable to impregnate 1 to 5 parts with little wiping remaining.
The wet wiper containing the disinfectant of the present invention has various surface cleaning, sterilization, antibacterial and the like, for example, belt conveyors and work tables in food factories, working tools such as stainless steel pads and bowls, tools used for making refrigerators and dishes, It is suitably used for toys, toilet seats, window glass, vehicle window glass, wash basins, human body cleaning, sterilization and disinfection.
下記に本発明の実施例を詳細に説明する。
実施例、比較例で使用する原料名（略称）、布帛名称は下記の通りである。
ラウリルジメチルベンジルアンモニウムクロライド（ラウリル基の純度９９質量％以上）：以下、Ｃ１２と略称する。
ミリスチルジメチルベンジルアンモニウムクロライド（ミリスチル基の純度９６質量％以上）：以下、Ｃ１４と略称する。
ミリスチルジメチルベンジルアンモニウムクロライド（ミリスチル基の純度８０質量％以上）：以下、Ｃ１４−１と略称する。
ショ糖ラウリン酸エステル（商品名：コスメライクＬ−１６０Ａ 第一工業製薬社製 ショ糖ラウリン酸エステル４０質量％）：以下、Ｌ−１６０Ａと略称する。
Examples of the present invention will be described in detail below.
Raw material names (abbreviations) and fabric names used in Examples and Comparative Examples are as follows.
Lauryldimethylbenzylammonium chloride (purity of lauryl group of 99% by mass or more): Hereinafter, abbreviated as C12.
Myristyldimethylbenzylammonium chloride (purity of myristyl group of 96% by mass or more): hereinafter abbreviated as C14.
Myristyldimethylbenzylammonium chloride (purity of myristyl group of 80% by mass or more): hereinafter abbreviated as C14-1.
Sucrose laurate (trade name: Cosmelike L-160A, Daiichi Kogyo Seiyaku Co., Ltd., sucrose laurate 40% by mass): hereinafter abbreviated as L-160A.
塩化ベンザルコニウム（５０質量％水溶液）：以下、ＣＡと略称する。
消毒用アルコール（商品名：日本薬局方 消毒用アルコール 和光純薬工業社製 ７６．９〜８１．４ｖ／ｖ％）：以下、７０％ＥＴＯＨと略称する。
レーヨン／ＰＰ、ＰＥ複合繊維（商品名：ＡＳ４０（スパンレース） 大和紡績社製 公定水分率：８０％親水性繊維が８０％）：以下、ＡＳ４０と略称する。
アクリル繊維（商品名：シャレリア 旭化成せんい社製 公定水分率２％ 親水性繊維が２％）：以下、シャレリアと略称する。
ＰＰ不織布（商品名：シンテックスＭ 東レ・ファイン社製 公定水分率０％ 親水性繊維が０％）：以下、シンテックスＭと略称する。
Benzalkonium chloride (50% by mass aqueous solution): hereinafter abbreviated as CA.
Disinfecting alcohol (trade name: Japanese Pharmacopoeia Disinfecting alcohol, Wako Pure Chemical Industries, Ltd. 76.9-81.4 v / v%): hereinafter abbreviated as 70% ETOH.
Rayon / PP, PE composite fiber (trade name: AS40 (spun lace), manufactured by Daiwa Boseki Co., Ltd. Official moisture content: 80% hydrophilic fiber is 80%): hereinafter abbreviated as AS40.
Acrylic fiber (trade name: Charelia, manufactured by Asahi Kasei Fibers Co., Ltd. Official moisture content: 2%, hydrophilic fiber: 2%): hereinafter abbreviated as Charelia.
PP non-woven fabric (trade name: Syntex M, manufactured by Toray Fine Co., Ltd., official moisture content 0%, hydrophilic fiber 0%): hereinafter abbreviated as Syntex M.
実施例、比較例中で行う性能評価試験方法は下記の通りである。
殺菌効果の評価：殺菌消毒剤１０ｍｌを滅菌試験管に分注し、各種（黄色ブドウ球菌、緑膿菌、大腸菌：初期菌数は１０６〜１０７ｃｆｕ／ｍｌ）菌液を各０．１ｍｌ接種し２０℃１５秒間作用させた後、ＳＣＤＬＰ寒天培地に各試験管から０．１ｍｌを塗抹し、３５℃４８時間培養後、菌数を測定し判定する。評価基準は以下の通りである。
○：１０ｃｆｕ／ｍｌ以下
△：１１〜１０２未満ｃｆｕ／ｍｌ
×：１０２ｃｆｕ／ｍｌ以上
The performance evaluation test methods performed in the examples and comparative examples are as follows.
Evaluation of bactericidal effect: Dispense 10 ml of bactericidal disinfectant into sterilized test tubes, and each 0.1 ml of various (S. aureus, Pseudomonas aeruginosa, E. coli: initial number of bacteria is 10 6 to 10 7 cfu / ml) After inoculating and allowing to act at 20 ° C. for 15 seconds, 0.1 ml from each test tube is smeared on the SCDLP agar medium, and after culturing at 35 ° C. for 48 hours, the number of bacteria is measured and determined. The evaluation criteria are as follows.
○: 10cfu / ml or less △: 11~10 2 less than cfu / ml
×: 10 2 cfu / ml or more
皮膚刺激（Ａ）性評価：殺菌消毒剤を適量、手にとって良く擦り合わせ後に皮膚の感じ方を官能評価にて判定する。評価基準は以下の通りである。
○：手に若干刺激を感じる
△：手に刺激を感じる
×：手にヒリヒリする刺激を感じる
Skin irritation (A) evaluation: An appropriate amount of a bactericidal disinfectant is rubbed well for the hands, and the feeling of the skin is determined by sensory evaluation. The evaluation criteria are as follows.
○: Slight irritation in hand △: I feel irritation in hand x: I feel irritation in my hand
皮膚刺激（Ｂ）性評価：日本白色種ウサギ雄の背部を除毛した健常皮膚部に殺菌消毒剤含有ワイパーを２．５ｃｍ×２．５ｃｍに裁断したものを直接貼付し、２４時間閉塞貼付を行い、３，２４、４８時間後にそれぞれ刺激反応の観察を行いＤｒａｉｚｅ法の判定基準に従って判定する。評価基準は以下の通りである。
一次刺激率が、
○：１．００以下
△：１．０１〜３．００
×：３．０１以上
Skin irritation (B) evaluation: Japanese white rabbits males were stripped of 2.5cm x 2.5cm wiper containing antibacterial disinfectant directly on healthy skin where hair was removed from the back, and 24 hours occlusion was applied. After 24 hours and 48 hours, the stimulus reaction is observed, and the determination is made according to the criteria for the Draize method. The evaluation criteria are as follows.
Primary stimulation rate is
○: 1.00 or less Δ: 1.01 to 3.00
X: 3.01 or more
匂いの評価：直接、殺菌消毒剤あるいは殺菌消毒剤含有ワイパーの匂いを嗅いで官能評価にて判定する。評価基準は以下の通りである。
○：不快臭がしない
△：僅かに不快臭がする
×：不快臭が強くする
Odor evaluation: The odor of a germicidal disinfectant or a germicidal disinfectant-containing wiper is directly smelled and judged by sensory evaluation. The evaluation criteria are as follows.
○: No unpleasant odor △: Slightly unpleasant odor ×: Strong unpleasant odor
黄変性評価：幅１６０ｍｍ×長さ２００ｍｍのＡＳ４０不織布１５０枚をロール状にした不織布ロール１部に対し２部の殺菌消毒剤を上方から含浸したウェットワイパーをボトルにプリセットした後、蓋をしないで１ケ月間、室温で開放した状態を観察し判定する。評価基準は以下の通りである。
○：変化なし
△：やや黄変している
×：黄変している
Yellowing evaluation: After pre-setting a wet wiper impregnated with 2 parts of a disinfectant from the top to 1 part of a nonwoven fabric roll made of 150 sheets of AS40 nonwoven fabric having a width of 160 mm and a length of 200 mm, the bottle is not covered. Observe and judge the open state at room temperature for 1 month. The evaluation criteria are as follows.
○: No change △: Slightly yellow ×: Yellowish
ＡＴＰ測定：１０×１３ｃｍのステンレスバッドに食肉を付着させＡＴＰ測定器（ＢＩＯＴＲＡＣＥ社製：商品名、ＵＮＩ―ＬＩＴＥ ＮＧ）にて相対発光量（ＲＬＵ：Ｒｅｌａｔｉｖｅ Ｌｉｇｈｔ Ｕｎｉｔ）を測定する（初期値）。その後直ちに殺菌消毒剤含有ワイパーで食肉が付着している箇所を縦５回、横５回を均等な力で拭き取り、相対発光量を測定する（直後値）。更にその状態で２４時間放置し拭き取った箇所を先と同様に縦５回、横５回を均等な力で拭き取り、相対発光量を測定する（２４Ｈ値）評価基準は下記の通りである。（直後値／初期値×１００）％あるいは（２４Ｈ値／初期値×１００）％の値が
○：５０％以下
△：５１％〜１００％
×：１０１％以上
ATP measurement: Meat is attached to a stainless steel pad of 10 × 13 cm, and the relative light emission amount (RLU: Relative Light Unit) is measured with an ATP measuring device (trade name, UNI-LITE NG) (initial value). Immediately thereafter, the portion where the meat is attached with the wiper containing a disinfectant and disinfectant is wiped off 5 times in the vertical direction and 5 times in the horizontal direction with equal force, and the relative light emission amount is measured (immediate value). Furthermore, in the state, the portion left for 24 hours and wiped off was wiped with the same force for 5 times in the vertical direction and 5 times in the horizontal direction, and the relative light emission amount was measured (24H value). The evaluation criteria are as follows. The value of (immediate value / initial value × 100)% or (24H value / initial value × 100)% is ○: 50% or less Δ: 51% to 100%
X: 101% or more
含浸状態の評価：１６０ｍｍ×２００ｍｍをロール状にした１５０枚のＡＳ４０不織布に殺菌消毒剤を上方から含浸させた後、不織布に含浸されている状態を官能評価にて判定する。評価基準は以下の通りである。
○：全体に含浸されている
△：部分的にしか含浸されていない
×：ほとんど含浸されていない
Evaluation of impregnation state: After impregnating a disinfectant from above with 150 AS40 nonwoven fabrics rolled into 160 mm × 200 mm, the state of impregnation into the nonwoven fabrics is determined by sensory evaluation. The evaluation criteria are as follows.
○: Impregnated entirely △: Partially impregnated ×: Almost not impregnated
[実施例１]
Ｃ１２：１．０質量％を精製水：９９．０質量％に溶解して殺菌消毒剤を作製した。
[Example 1]
C12: 1.0% by mass was dissolved in purified water: 99.0% by mass to prepare a disinfectant.
[比較例１]
ＣＡ：２．０質量％を精製水：９８．０質量％に溶解して殺菌消毒剤を作製した。
[Comparative Example 1]
CA: 2.0% by mass was dissolved in purified water: 98.0% by mass to prepare a disinfectant.
[実施例７]
Ｃ１４：０．１質量％を精製水：９９．９質量％に溶解して殺菌消毒剤を作製した。
[Example 7]
C14: 0.1% by mass was dissolved in purified water: 99.9% by mass to prepare a disinfectant.
[比較例３]
Ｃ１４−１：０．１質量％を精製水：９９．９質量％に溶解して殺菌消毒剤を作製した。
[Comparative Example 3]
C14-1: 0.1% by mass was dissolved in purified water: 99.9% by mass to prepare a disinfectant.
[実施例２]
Ｃ１４：３．０質量％及びＬ−１６０Ａ：２．５質量％を混合した後、精製水：９４．５質量％に溶解して作製した殺菌消毒剤をＡＳ４０：１部に対し２部を含浸させたウェットワイパーを作製した。
[Example 2]
C14: 3.0% by mass and L-160A: 2.5% by mass were mixed, and then purified water: 94.5% by mass was dissolved. A wet wiper was prepared.
[比較例２]
ＣＡ：６．０質量％及びＬ−１６０Ａ：２．５質量％を混合した後、精製水：９１．５質量％に溶解して作製した殺菌消毒剤をＡＳ４０：１部に対し２部を含浸させたウェットワイパーを作製した。
[Comparative Example 2]
After mixing CA: 6.0% by mass and L-160A: 2.5% by mass, the disinfectant prepared by dissolving in purified water: 91.5% by mass was impregnated with 2 parts of AS40: 1 part. A wet wiper was prepared.
[実施例３]
Ｃ１２：３．０質量％を精製水：９７．０質量％に溶解して作製した殺菌消毒剤をＡＳ４０：１部に対し２部を含浸させたウェットワイパーを作製した。
[Example 3]
A wet wiper was prepared by impregnating 2 parts of AS40: 1 part with a disinfectant prepared by dissolving C12: 3.0% by mass in purified water: 97.0% by mass.
[比較例４]
Ｃ１４−１：１０．０質量％を精製水：９０．０質量％に溶解して作製した殺菌消毒剤をシャレリア：１部に対し３部を含浸させたウェットワイパーを作製した。
[Comparative Example 4]
C14-1: A wet wiper was prepared by impregnating 3 parts per 1 part of a sterilizing disinfectant prepared by dissolving 10.0% by mass of purified water: 90.0% by mass.
[実施例４]
Ｃ１２：３．０質量％を精製水：９７．０質量％に溶解して作製した殺菌消毒剤をＡＳ４０：１部に対し０．３部を含浸させたウェットワイパーを作製した。
[Example 4]
A wet wiper was produced by impregnating 0.3 part of AS40: 1 part of a disinfectant prepared by dissolving C12: 3.0% by mass in purified water: 97.0% by mass.
[実施例５]
Ｃ１４：１０．０質量％を精製水：９０．０質量％に溶解して作製した殺菌消毒剤をシャレリア：１部に対し３部を含浸させたウェットワイパーを作製した。
[Example 5]
C14: A wet wiper was prepared by impregnating 3 parts per 1 part of a disinfectant prepared by dissolving 10.0% by mass in purified water: 90.0% by mass.
[実施例６]
Ｃ１４：１０．０質量％を精製水：９０．０質量％に溶解して作製した殺菌消毒剤をシンテックスＭ：１部に対し３部を含浸させたウェットワイパーを作製した。
[Example 6]
A wet wiper was prepared by impregnating 3 parts of Syntex M: 1 part of a disinfectant prepared by dissolving C14: 10.0% by mass in purified water: 90.0% by mass.
[比較例５]
７０％ＥＴＯＨ：１０．０質量％を精製水：９０．０質量％に溶解して作製した殺菌消毒剤をシャレリア：１部に対し３部を含浸させたウェットワイパーを作製した。
実施例、比較例の評価結果を表１、表２に示す。
[Comparative Example 5]
A wet wiper was prepared by impregnating 3 parts per 1 part of a disinfectant prepared by dissolving 70% ETOH: 10.0% by mass in purified water: 90.0% by mass.
The evaluation results of Examples and Comparative Examples are shown in Tables 1 and 2.
本発明は、殺菌消毒効果を求められる食品を扱う場所や病院等の殺菌消毒剤として好適である。 INDUSTRIAL APPLICABILITY The present invention is suitable as a sterilizing / disinfecting agent for a place where a food requiring a sterilizing / disinfecting effect is handled or a hospital.
Claims (8)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004252227A JP2006069919A (en) | 2004-08-31 | 2004-08-31 | Germicidal disinfectant |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004252227A JP2006069919A (en) | 2004-08-31 | 2004-08-31 | Germicidal disinfectant |
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| Publication Number | Publication Date |
|---|---|
| JP2006069919A true JP2006069919A (en) | 2006-03-16 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004252227A Pending JP2006069919A (en) | 2004-08-31 | 2004-08-31 | Germicidal disinfectant |
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| Country | Link |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009256338A (en) * | 2008-03-24 | 2009-11-05 | Asahi Kasei Chemicals Corp | Sterilizing disinfectant-containing wet wiper |
| JP4518437B1 (en) * | 2009-06-01 | 2010-08-04 | 英治 川西 | Western-style toilet disinfection and deodorant spray equipment |
| CN104434652A (en) * | 2014-11-19 | 2015-03-25 | 铜陵麟安生物科技有限公司 | Disinfectant wipes |
| JP2016530410A (en) * | 2013-06-20 | 2016-09-29 | アーチ・ケミカルズ・インコーポレーテッド | Building materials with antifungal properties |
| JP2016175879A (en) * | 2015-03-20 | 2016-10-06 | 旭化成株式会社 | Wet wiper and method for producing the same |
| KR101798978B1 (en) * | 2016-04-12 | 2017-11-20 | 주식회사 명진뉴텍 | Wet wipes composition comprising Laurylpyridinium chloride for enhancing of diffusivity in wet wipe's fabric and wet wipes including thereof |
| JP2020523293A (en) * | 2017-06-16 | 2020-08-06 | ダブリュー．エム． バアー アンド カンパニー， インコーポレイテッド | Surface germicide with residual germicidal properties |
| JP2021009129A (en) * | 2019-06-28 | 2021-01-28 | ユニ・チャーム株式会社 | Evaluation method for evaluating presence or absence of yellow discoloration of wet sheet |
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| JPS62129202A (en) * | 1985-07-10 | 1987-06-11 | Takeda Chem Ind Ltd | Sterilization and disinfection agent and method for using thereof |
| JPH0646968A (en) * | 1992-07-31 | 1994-02-22 | Daio Paper Corp | Wet tissue |
| JP2001294561A (en) * | 2000-04-13 | 2001-10-23 | Kao Corp | Quaternary ammonium salt composition |
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| JPS6176401A (en) * | 1984-09-19 | 1986-04-18 | Takeda Chem Ind Ltd | Germicidal disinfectant and method for germicidal disinfection |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009256338A (en) * | 2008-03-24 | 2009-11-05 | Asahi Kasei Chemicals Corp | Sterilizing disinfectant-containing wet wiper |
| JP4518437B1 (en) * | 2009-06-01 | 2010-08-04 | 英治 川西 | Western-style toilet disinfection and deodorant spray equipment |
| JP2010274038A (en) * | 2009-06-01 | 2010-12-09 | Eiji Kawanishi | Disinfecting and odor-eliminating spray device for western-style toilet |
| JP2016530410A (en) * | 2013-06-20 | 2016-09-29 | アーチ・ケミカルズ・インコーポレーテッド | Building materials with antifungal properties |
| CN104434652A (en) * | 2014-11-19 | 2015-03-25 | 铜陵麟安生物科技有限公司 | Disinfectant wipes |
| JP2016175879A (en) * | 2015-03-20 | 2016-10-06 | 旭化成株式会社 | Wet wiper and method for producing the same |
| KR101798978B1 (en) * | 2016-04-12 | 2017-11-20 | 주식회사 명진뉴텍 | Wet wipes composition comprising Laurylpyridinium chloride for enhancing of diffusivity in wet wipe's fabric and wet wipes including thereof |
| CN107410317A (en) * | 2016-04-12 | 2017-12-01 | 明进新科技股份有限公司 | Improve the diffusible wet tissue composition in wet tissue fabric and the wet tissue containing said composition |
| JP2020523293A (en) * | 2017-06-16 | 2020-08-06 | ダブリュー．エム． バアー アンド カンパニー， インコーポレイテッド | Surface germicide with residual germicidal properties |
| JP2021009129A (en) * | 2019-06-28 | 2021-01-28 | ユニ・チャーム株式会社 | Evaluation method for evaluating presence or absence of yellow discoloration of wet sheet |
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