CN107410317A - Improve the diffusible wet tissue composition in wet tissue fabric and the wet tissue containing said composition - Google Patents
Improve the diffusible wet tissue composition in wet tissue fabric and the wet tissue containing said composition Download PDFInfo
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- CN107410317A CN107410317A CN201710232657.4A CN201710232657A CN107410317A CN 107410317 A CN107410317 A CN 107410317A CN 201710232657 A CN201710232657 A CN 201710232657A CN 107410317 A CN107410317 A CN 107410317A
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/28—Heterocyclic compounds containing nitrogen in the ring
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
- A01N31/14—Ethers
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing keto or thioketo groups as part of a ring, e.g. cyclohexanone, quinone; Derivatives thereof, e.g. ketals
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/06—Unsaturated carboxylic acids or thio analogues thereof; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/10—Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/28—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof containing the group; Thio analogues thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/52—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing groups, e.g. carboxylic acid amidines
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
- A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
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- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
- A47K10/00—Body-drying implements; Toilet paper; Holders therefor
- A47K10/16—Paper towels; Toilet paper; Holders therefor
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
- A47K7/00—Body washing or cleaning implements
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
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Abstract
The wet tissue composition being improved the present invention relates to a kind of diffusivity and the wet tissue containing said composition, the wet tissue composition contains chlorination dococylpyridinium, and selected from hydroxamic acid and its esters, alkanediol, organic acid, hexamidine and its esters, glycine class, the compound of one or more of tropolone and Chlorphenesin, the wet tissue composition is to bacterium, the sterilizing power of fungi and Burkholderia category is excellent, the diffusivity of wet tissue fabric is excellent, so as to easily prepare the excellent quality of wet tissue and wet tissue, so as to expect to make to use it to replace existing cetylpyridinium chloride.
Description
Technical field
The present invention relates to one kind containing chlorination dococylpyridinium (Laurylpyridinium chloride) as main
The wet tissue composition and the wet tissue containing it that the diffusivity in wet tissue fabric of composition is improved.
Background technology
Wet tissue (wet wipes) is the non-woven fabrics containing moisture for cleaning human body, since nineteen fifty for mid-term
Have in family or child-care facility, old man's welfare facility, restaurant, hospital of child etc. and used with multiple use.The wet tissue master at initial stage
Will travelling when be used for clean, recently, cleaning the skin of child, the pad made up or wiped the sweat, pain of alleviation, personal hygiene,
It is used to clean the pollutant being attached on skin in the care of animal, health control, factory work, according to the composition added in wet tissue
Difference, its purposes it is also different (Seo J.H., et al., 2015；Moo S.C., 2016).
The composition added in wet tissue is commonly included in addition NMF or spices etc. in Purified Water and added according to different purposes
The functional components added, and as the composition that must be added, it is wet to cause also comprising the preservative agent such as disinfection sanitizer and preservative
Towel can preserve for a long time in the state of moistening.But generally, wet tissue is not to be cleaned after use by water
Product, it is high directly to residue in the possibility of skin accordingly, there exist the preservative agent in product, due to product using position be mouth,
Hand etc. is for the sensitive position of chemicals, therefore, it is necessary to the stimulation to skin is small, excellent in stability and for remaining in skin
On foreign matter and pathogenic microbes removal ability it is excellent.
Cetylpyridinium chloride (the cetylpyridinium of one of presently the most widely used preservative
Chloride, CPC) it is quaternary ammonium cation, there is bactericidal effect to bacterium and microorganism, it is known that it, which has, prevents tooth from forming spot
Block (plaque), and reduce the effect of gingivitis, so as to for cleaning agent for mouth cavity, toothpaste, mouthspray, nasal spray, wet
In towel etc..But cetylpyridinium chloride can generate substantial amounts of foam for characteristic aspect, so as to need and defoamer one
Rise and use, in this case, it may appear that the problem of in the pollution and process on preparation section, and more frequently being occur wet
Sliding, wet tissue adhesive band occurs as and the diffusion in wet tissue fabric is bad, is difficult to keep out asking for microorganism pollution so as to exist
Topic.
In addition, using cetylpyridinium chloride and benzalkonium chloride (Benzalkonium chlor ide, BKC) recently
As in the wet tissue of preservative, confirming Burkholderia cepacia (Burkholderi a cepacia) to preservative i.e. pair
Preservation material in wet tissue has tolerance, so as to the phenomenon largely bred.Therefore, current present situation is to need to develop a kind of energy
Enough instead of cetylpyridinium chloride and the novel wet tissue preservative of benzalkonium chloride.
In order to overcome the limitation and shortcoming of cetylpyridinium chloride and benzalkonium chloride as previously mentioned, in South Korea
The usage amount for the Climbazole (Climbazole) being commonly used as the preservative ingredient of cosmetics is in increased trend.Chlorine
Miaow bar azoles is white crystalline powder, it is known that it is in the Environmental Studies non-profit organization EWG in U.S. Skin Deep grades
For 0 grade, stimulation degree or risk factor are low compared with other compositions, and have exclusiveness to avette nasal cavity fungi and trichophyta, tool
There is lasting bactericidal effect.But Climbazole is not soluble in water, it is known that has the harmful substance of genotoxic potential.
Therefore, present situation is that there is an urgent need to develop one kind to replace cetylpyridinium chloride, benzalkonium chloride and chlorine miaow
Bar azoles, preservative that antibacterial activity is excellent and harmless.
Chlorination dococylpyridinium (Laurylpyridinium chloride, LPC, dodecylpyridini um
Chloride antibacterial effect) is excellent and stimulation to skin is small.Further, since it is excellent to the solubility of water, for wet tissue
During fabric, the diffusivity in fabric is excellent, so as to be a kind of preservative for being suitable for wet tissue.
Therefore, chlorination dococylpyridinium is used as preservative by the present invention, during wet tissue composition is studied, is passed through
Confirming the wet tissue composition contained using chlorination dococylpyridinium as main component of the present invention, there is excellent antibacterial to live
Property, and the diffusivity in fabric is excellent, so as to complete the present invention.
As the chlorination 12 recorded in the Japanese granted patent the 4030633rd of prior art as fungi-proofing mould inhibitor
Alkyl pyridine, but the method for also describing the adsorption rate for reducing the fungi-proofing mould inhibitor on wet tissue fabric, and suitable for this
Fungi-proofing mould inhibitor cetylpyridinium chloride, therefore with the present invention have excellent antibacterial effect and it is diffusible, with chlorine
Changing the wet tissue composition that dococylpyridinium contains as main component has difference.In addition, Korean granted patent
The anticorrosive composite containing cetylpyridinium chloride is recorded in No. 1506185, therefore, contains chlorination 12 with of the invention
Alkyl pyridine is structurally different as the wet tissue composition of main component, is recorded in US granted patent the 9226882nd
With the bactericidal composition of wet tissue form generating, but the chlorination dococylpyridinium of the present invention is not recorded.
Prior art literature
Patent document
(patent document 0001) Japanese granted patent the 4030633rd, the reduction method of the adsorbance of fungi-proofing mould inhibitor,
2007.10.26. authorize.
(patent document 0002) Korean granted patent the 1506185th, hinder the anti-corrosion group of quaternary ammonium compoundses resistant bacterium
Compound, 2015.03.20. are authorized.
(patent document 0003) US granted patent the 9226882nd, Eco-friendly non-aqu eous
antimicrobial composition comprising tropolone with 1,3-proranediol a nd/or
Sorbitan caprylate, 2016.01.05. mandates.
Non-patent literature
(non-patent literature 0001) Moo S.C., Bacterial Contamination in Disposabl e Wet
Wipes from General Restaurants, Korean J.Clin.Lab.Sci., 48 (3), 237-241,2016.
(non-patent literature 0002) Seo J.H., et al., Studies on the antibacterial act
Ivity of wet-tissue saturated with electrolytic water of NaCl solution, Jour
Nal of Korea TAPPI, 47 (6), 147-153,2015.
The content of the invention
Contain chlorination dococylpyridinium carrying in high humidity as main component it is an object of the present invention to provide a kind of
Diffusible wet tissue composition in towel fabric.
It is further an object that, there is provided it is a kind of comprising chloride containing dococylpyridinium as main component can
Improve the wet tissue of the diffusible wet tissue composition in wet tissue fabric.
The diffusible wet tissue composition in wet tissue fabric is improved the present invention relates to a kind of, it contains a) chlorination dodecane
Yl pyridines (Laurylpyridinium chloride)；And b) it is selected from caprylyl hydroxamic acid (Capryl hydroxamic
Acid), xenyl hydroxamic acid (Biphenylhydroxamic acid), cinnamoyl hydroxamic acid
(Cinnamoylhydroxamic acid), ethohexadiol (Octanediol), hexylene glycol (Hexanediol), propane diols
(Propanediol), benzoic acid (Benzoic acid), sodium benzoate (Sodium benzoate), sorbic acid (Sorbic
Acid), potassium sorbate (Potassium sorbate), dehydroactic acid (Dehydroacetic acid), anhydrous sodium acetate
(Sodium dehydroacetic acid), propionic acid (Propionic acid), sodium propionate (Sodium propionate), first
Sour (Formic acid), sodium formate (Sodium formate), hexamidine disalt (Hexamidine diisethionate),
Decoyl glycine (Capryloyl glycine), endecatylene acyl glycine (Undecylenoyl glycine), C12-C14
Alkyl diamino ethyl glycines hydrogen chloride (C12-C14alkyl diaminoethyl glycine HCl), lauryl two are sub-
Second diaminourea glycine (Lauryl diethylene diamino glycine), lauryl aminopropyl glycine (Lauryl
Aminopropyl glycine), one kind in tropolone (Tropolone) and Chlorphenesin (Chlorphenesin)
Compound above.
The wet tissue composition can a) the chlorination dococylpyridinium containing 0.01~30 weight %；And 0.001~
40 weight % b) selected from caprylyl hydroxamic acid, xenyl hydroxamic acid, cinnamoyl hydroxamic acid, ethohexadiol, hexylene glycol,
Propane diols, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, dehydroactic acid, anhydrous sodium acetate, propionic acid, sodium propionate, formic acid,
Sodium formate, hexamidine disalt, decoyl glycine, endecatylene acyl glycine, C12-C14 alkyl diamino ethyl glycines chlorinations
One kind in the sub- second diaminourea glycine of hydrogen, lauryl two, lauryl aminopropyl glycine, tropolone and Chlorphenesin
Compound above.
In the wet tissue composition, chlorination dococylpyridinium (Laurylpyridinium chloride)；And it is selected from
Caprylyl hydroxamic acid, xenyl hydroxamic acid, cinnamoyl hydroxamic acid, ethohexadiol, hexylene glycol, propane diols, benzoic acid, benzene
Sodium formate, sorbic acid, potassium sorbate, dehydroactic acid, anhydrous sodium acetate, propionic acid, sodium propionate, formic acid, sodium formate, hexamidine two
Salt, decoyl glycine, endecatylene acyl glycine, C12-C14 alkyl diamino ethyl glycines hydrogen chloride, two sub- second of lauryl
The compound of one or more of diaminourea glycine, lauryl aminopropyl glycine, tropolone and Chlorphenesin can
With with 1:10~10:1 part by weight mixing.
The compound is preferably caprylyl hydroxamic acid, xenyl hydroxamic acid, cinnamoyl hydroxamic acid, pungent two
Alcohol, hexylene glycol, propane diols, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, dehydroactic acid, anhydrous sodium acetate, propionic acid
(Propionic acid), sodium propionate, formic acid and sodium formate, more preferably caprylyl hydroxamic acid, xenyl hydroxamic acid and
Cinnamoyl hydroxamic acid.
The wet tissue composition can further contain NMF and pH adjusting agent.
The wet tissue composition can be to aurococcus (Staphylococcus aureus), large intestine bar
Bacterium (Escherichia coli), Pseudomonas aeruginosa (Pseudomonas aeruginosa), Xi Shi enterobacterias (Enterobacter
Hirae), Brazilian aspergillus niger (Aspergillus brasiliensis), Candida albicans (Candida albicans), soil
Mycobacterium (Mycobacterium terrae) and Burkholderia cepacia (Burkholderia cepacia), which have, to kill
Bacterium power.
According on the other hand, the present invention relates to the wet tissue containing the wet tissue composition.
Below, the present invention is described in detail.
The wet tissue composition can contain a) chlorination dococylpyridinium；And b) selected from caprylyl hydroxamic acid, connection
Benzohydroxamic acid, cinnamoyl hydroxamic acid, ethohexadiol, hexylene glycol, propane diols, benzoic acid, sodium benzoate, sorbic acid, mountain
Potassium sorbate, dehydroactic acid, anhydrous sodium acetate, propionic acid, sodium propionate, formic acid, sodium formate, hexamidine disalt, decoyl glycine, 11
Carbene acyl glycine, C12-C14 alkyl diamino ethyl glycines hydrogen chloride, the sub- second diaminourea glycine of lauryl two, bay
The compound of one or more of base aminopropyl glycine, tropolone and Chlorphenesin.
The wet tissue composition can be 0.01~30 weight % a) chlorination dodecane on the basis of composition total weight
Yl pyridines；And 0.001~40 weight % b) selected from caprylyl hydroxamic acid, xenyl hydroxamic acid, the different hydroxyl of cinnamoyl
Oxime acid, ethohexadiol, hexylene glycol, propane diols, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, dehydroactic acid, anhydrous acetic acid
Sodium, propionic acid, sodium propionate, formic acid, sodium formate, hexamidine disalt, decoyl glycine, endecatylene acyl glycine, C12-C14 alkyl
The sub- second diaminourea glycine of diamino ethyl glycine hydrogen chloride, lauryl two, lauryl aminopropyl glycine, cycloheptatriene phenol
The compound of one or more of ketone and Chlorphenesin mixes.Preferably, 0.01~5 weight % a) chlorination dodecyl
The ratio of pyridine and 0.005~5 weight % b) more than one the compound, more preferably 0.03~0.5 weight %'s
A) ratio of chlorination dococylpyridinium and 0.005~1 weight % b) more than one the compound.
The chlorination dococylpyridinium is excellent for the antibacterial effect of bacterium and mould, especially to golden yellow Niang Nong Portugals
Grape coccus (Staphylococcus aureus), Escherichia coli (Escherichia coli), Xi Shi enterobacterias
(Enterobacter hirae), Pseudomonas aeruginosa (Pseudomonas aeruginosa) show excellent antibacterial effect.This
Outside, because the stimulation to skin is small, it is adapted to prepare the wet tissue directly with skin contact, it is excellent for the solubility of water, so that
In wet tissue fabric in use, because the diffusivity in fabric is excellent, so as to can easily be used when preparing wet tissue.
The chlorination dococylpyridinium can replace now widely used preservative cetylpyridinium chloride
Compound, substantial amounts of foam can be produced in the characteristic of cetylpyridinium chloride, in order to prevent the generation of a large amount of foams, entered
In the process of one step addition defoamer, the phenomenon that pollution and wet and slippery sense, the adhesion of wet tissue are taken out of can be produced, and in wet tissue fabric
The problem of being inside difficult to diffusion, and the chlorination dococylpyridinium can overcome these problems.
Burkholderia cepacia energy of the chlorination dococylpyridinium for acquisition cetylpyridinium chloride patience
Antibacterial activity is enough shown, so as to instead of cetylpyridinium chloride.
The content ratio of the chlorination dococylpyridinium, can be 0.01~30 weight in terms of wet tissue composition total weight
Measure %.If the content ratio of the chlorination dococylpyridinium is less than 0.01 weight %, the sterilizing power of wet tissue composition is not
The sterilizing power standard value for preparing and being required during wet tissue can be reached, even more than 30 weight %, also without big in terms of sterilizing power
Difference, solubility is limited to during dissolving, it is necessary to extra additive and heating process, therefore do not have economy.
In order to increase the antibacterial effect of the chlorination dococylpyridinium, above-claimed cpd, the compound can be mixed
Can include hydroxamic acid and its esters (hydroxamic acid and its salts), alkanediol (alkanediol),
Organic acid, hexamidine and its esters (hexamidine and its salts), glycine class (glycine), cycloheptatriene phenol
Ketone (tropolone) and Chlorphenesin (chlorphenesin)
The hydroxamic acid and its esters can be caprylyl hydroxamic acid, xenyl hydroxamic acid, the different hydroxyl of cinnamoyl
Oxime acid, it is not limited to this.
The alkanediol can be ethohexadiol, hexylene glycol, propane diols, it is not limited to this.
The organic acid can be benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, dehydroactic acid, anhydrous sodium acetate,
Propionic acid (Propionic acid), sodium propionate, formic acid, sodium formate, it is not limited to this.
The hexamidine and its esters can be hexamidine disalts, but not limit and this.
The glycine class can be that decoyl glycine, endecatylene acyl glycine, C12-C14 alkyl diamino ethyls are sweet
The sub- second diaminourea glycine of propylhomoserin hydrogen chloride, lauryl two, lauryl aminopropyl glycine, but not limit and this.
In terms of wet tissue composition total weight, the content ratio of the compound can be 0.001~40 weight %, if small
In 0.001 weight %, then the sterilizing power of wet tissue composition can not reach the sterilizing power standard value for preparing and being required during wet tissue, even if
It is preferred without economy, therefore not also without big difference in terms of sterilizing power more than 40 weight %.
The wet tissue composition can be chlorination dococylpyridinium；It is and different selected from caprylyl hydroxamic acid, xenyl
Hydroximic acid, cinnamoyl hydroxamic acid, ethohexadiol, hexylene glycol, propane diols, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate,
Dehydroactic acid, anhydrous sodium acetate, propionic acid, sodium propionate, formic acid, sodium formate, hexamidine disalt, decoyl glycine, endecatylene acyl
Glycine, C12-C14 alkyl diamino ethyl glycines hydrogen chloride, the sub- second diaminourea glycine of lauryl two, lauryl ammonia third
The compound of one or more of base glycine, tropolone and Chlorphenesin is with 1:4000~10:1 part by weight mixes
Close, preferably with 1:100~10:1 part by weight mixing, more preferably 1:10~10:1 part by weight.
The diffusivity refers to that wet tissue composition is absorbed the degree spread in wet tissue fabric, if diffusivity is low,
Antiseptic composition can not be uniformly spread in wet tissue fabric, therefore can be given birth in the not part containing antiseptic composition
Long microorganism, so as to can because peculiar smell, discoloration, microorganism addition product cause it is allergic.
The wet tissue composition is excellent for the bactericidal effect of bacterium and mould, especially to aurococcus
(Staphylococcus aureus), Escherichia coli (Escherichia coli), Pseudomonas aeruginosa (Pseudomonas
Aeruginosa), Xi Shi enterobacterias (Enterobacter hirae), Brazilian aspergillus niger (Aspergillus
Brasiliensis), Candida albicans (Candida albicans), soil mycobacterium (Mycobacterium terrae)
And the bactericidal effect of Burkholderia cepacia (Burkholderia cepacia) is the most excellent.
The wet tissue composition directly can be used or be diluted in Purified Water and use.
The dilution of the wet tissue composition can dilute 1 times~1000 times on the basis of diluent gross weight, but according to this
The judgement of art personnel can be different.
The wet tissue composition is except the chlorination dococylpyridinium；And selected from caprylyl hydroxamic acid, xenyl
Hydroxamic acid, cinnamoyl hydroxamic acid, ethohexadiol, hexylene glycol, propane diols, benzoic acid, sodium benzoate, sorbic acid, sorbic acid
Potassium, dehydroactic acid, anhydrous sodium acetate, propionic acid, sodium propionate, formic acid, sodium formate, hexamidine disalt, decoyl glycine, endecatylene
Acyl glycine, C12-C14 alkyl diamino ethyl glycines hydrogen chloride, the sub- second diaminourea glycine of lauryl two, lauryl ammonia
Outside the compound of one or more of glycinate, tropolone and Chlorphenesin, additional add can also be contained
Add agent to prepare.
The additive can be NMF (moisturizer), pH adjusting agent (pH regulator), thickener
(thickener), stabilizer (stabilizer), steering wheel (perfume), dispersant (dispersant) and coloring material,
But it is preferred that NMF and pH adjusting agent.
The NMF can be propane diols (Propylene glycol), hexylene glycol (Hexylene glycol), fourth two
Alcohol (Butylene glycol), glycerine (Glycerin) and methyl propanediol (Methylpropanediol) etc., preferably third
Glycol, hexylene glycol and butanediol, but not limit and this.
The pH adjusting agent can be citric acid (Citric acid), sodium citrate (Sodium citrate), EDTA
(Ethylenediaminet etraacetic acid) -2NA, EDTA-4NA, KOH etc., optimization citric acid and EDTA-2NA, but
It is not limited to that.
In addition, the present invention relates to a kind of wet tissue containing the wet tissue composition.
The wet tissue can be by wet tissue fabric, impregnating the chlorination dodecyl pyrrole containing 0.01~30 weight %
Pyridine；And 0.001~40 weight % selected from caprylyl hydroxamic acid, xenyl hydroxamic acid, cinnamoyl hydroxamic acid, pungent
Glycol, hexylene glycol, propane diols, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, dehydroactic acid, anhydrous sodium acetate, propionic acid,
Sodium propionate, formic acid, sodium formate, hexamidine disalt, decoyl glycine, endecatylene acyl glycine, C12-C14 alkyl diaminourea second
The sub- second diaminourea glycine of base glycine hydrogen chloride, lauryl two, lauryl aminopropyl glycine, tropolone and chlorobenzene
Prepared by the wet tissue composition of the compound of one or more of sweet ether, it is preferable that can contain 0.01~5 weight by dipping
The wet tissue composition for measuring % chlorination dococylpyridinium and 0.005~5 weight % more than one the compound is made
It is standby, it is highly preferred that can be by impregnating the chlorination dococylpyridinium containing 0.03~0.5 weight % and 0.005~1 weight %
The wet tissue composition of more than one the compound prepare, but can according to the judgement of those skilled in the art without
Together.
The wet tissue containing above-mentioned wet tissue composition by having excellent bactericidal effect, it is possible to reduce wet tissue it is wet and slippery
The phenomenon that sense and adhesion are taken out of.
The wet tissue contains the wet tissue composition, can include being prepared by the known method of this area all wet
Towel.
The present invention relates to a kind of wet tissue for containing chlorination dococylpyridinium and being improved as the diffusivity of main component
Composition, in more detail, it is related to one kind and contains chlorination dococylpyridinium, and selected from hydroxamic acid and its esters, alkane two
The compound of one or more of alcohol, organic acid, hexamidine and its esters, glycine class, tropolone and Chlorphenesin
The wet tissue composition that is improved of diffusivity and wet tissue containing said composition.
Confirm that the wet tissue composition is excellent to the sterilizing power of bacterium and mould, because the diffusivity of wet tissue fabric is excellent,
So as to easily prepare wet tissue, and the excellent quality of the wet tissue prepared.
Thus, it is possible to expect, the chlorination dococylpyridinium that contains by the use of the present invention obtains as the diffusivity of main component
Wet tissue composition to raising can substitute the existing antiseptic composition containing cetylpyridinium chloride.
Brief description of the drawings
Fig. 1 is to show the confirmation result of wet tissue composition of the invention to the antibacterial activity of bacterium, fungi and Burkholderia.
Embodiment
Below, to a preferred embodiment of the present invention will be described in detail.But the present invention be not limited to it is described herein
Embodiment, other forms can also be embodied as.Embodiment is in order that the content that must be introduced herein is very complete, to this area
Technical staff fully transmits the thought of the present invention and provided.
Embodiment 1：The preparation of wet tissue composition containing chlorination dococylpyridinium and a kind of compound
It is prepared for containing chlorination dococylpyridinium and a kind of compound, of the invention with chlorination dococylpyridinium making
For the wet tissue composition of main component, now, it will be equivalent to composition and the material of content in table 1 below and be added in Purified Water mix
Close to prepare.
Table 1
Embodiment 2：The preparation of wet tissue composition containing chlorination dococylpyridinium and 2 kinds of compounds
It is prepared for containing chlorination dococylpyridinium and 2 kinds of compounds, of the invention with chlorination dococylpyridinium making
For the wet tissue composition of main component, now, it will be equivalent to composition and the material of content in table 2 below and be added in Purified Water mix
Close to prepare.
Table 2
Embodiment 3：The preparation of wet tissue composition containing chlorination dococylpyridinium and 3 kinds of compounds
It is prepared for containing chlorination dococylpyridinium and more than 3 kinds compounds, of the invention with chlorination dodecyl pyrrole
Wet tissue composition of the pyridine as main component, now, it will be equivalent to composition and the material of content in Table 3 below and be added to Purified Water
It is middle to mix to prepare.
Table 3
Preparation of the 1~comparative example of comparative example 21 as the wet tissue composition of comparison other
It will be equivalent to composition and the material of content in table 4 below and be added to mix in Purified Water prepare as comparison other
Wet tissue composition.
Table 4
The antibacterial activity of the wet tissue composition of experimental example 1 confirms
Wet tissue composition using the 1~embodiment of embodiment 3 and comparative example confirms antibacterial activity, is confirming antibacterial
When active, bacterium, which uses, is mixed with aurococcus (Staphyloco ccus aureus), Escherichia coli
The bacterium of (Escherichia coli), Pseudomonas aeruginosa (Pseudomonas aer uginosa), fungi, which uses, to be mixed with bar
Western aspergillus niger (Aspergillus brasiliensis), the bacterium of Candida albicans (Candida albicans), and onion
Burkholderia (Burkholde ria cepacia).
The antibacterial activity test is implemented based on U.S.Pharmacopoeia benchmark.Specifically, in order to confirm subtracting for bacterium
Less and the death rate, tested using plating method, the wet tissue composition is inoculated into bacterium mixed liquor (bacterium 106
~107CFU/ml, fungi 105~106CFU/ml, Burkholderia 106~107CFU/ml in), it is applied to plating medium
On, then bacterium is cultivated 24 hours at 30~35 DEG C, fungi is cultivated 72 hours at 25 DEG C, and Burkholderia is at 30~35 DEG C
Lower culture 48 hours.Now, control group will be used as without the bacterium mixed liquor of wet tissue compositions-treated.After cultivating bacterium respectively,
The bacterium colony (colony) generated in plating medium is counted, the death rate of bacterium is then calculated using following formula 1, and will
The results are shown in table 5 and Fig. 1.
Formula 1
The death rate of bacterium=(the inoculation bacterium number of (bacterium number of residual in inoculation bacterium number-wet tissue of control group)/control group) ×
100
The benchmark that can act as the death rate of the bacterium of wet tissue composition is more than 99.9%, if during less than 99.9%, no
It is adapted to prepare wet tissue.
Table 5
As shown in Fig. 1 and above-mentioned table 5, the wet tissue composition of 1~embodiment of embodiment 3 is for bacterium, fungi and primary kirschner
The bacterium killing office of bacterium is more than 99.9%, on the other hand, as 1~comparative example of comparative example 8, chlorination dococylpyridinium and change
Compound contains a kind of situation, as comparative example 9 and comparative example 10, the content of chlorination dococylpyridinium and compound respectively
In the case of content less than the present invention, it is less than 99.9% for the bacterium death rate of bacterium, fungi and Burkholderia.
In addition, the present invention replaces the wet tissue group of the chlorination dococylpyridinium of the present invention containing cetylpyridinium chloride
In the case of compound (12~comparative example of comparative example 21), a part of composition (comparative example 12, comparative example 14, comparative example 16, ratio
Compared with example 17, comparative example 19) in for Burkholderia the bacterium death rate be less than 99.9%, exist and be not above as wet tissue composition
A reference value situation, even if the bacterium death rate more than a reference value, in the experiment of fabric diffusivity in following experimental examples 2, expands
Dissipate property it is low, so as to as wet tissue composition in use, limitation be present.
Pass through the above, it is known that the wet tissue composition of the invention for containing chlorination dococylpyridinium as main component
It is high to the bacterium death rate of bacterium, fungi and Burkholderia, especially compared with the cetylpyridinium chloride primarily now used,
It is excellent to the bacterium death rate of Burkholderia, therefore, it can expect to be used as the wet tissue group of alternative cetylpyridinium chloride
Compound.
The diffusible confirmation of fabric of the wet tissue composition of experimental example 2
When preparing wet tissue, the center section of wet tissue fabric can be sprayed wet tissue composition, in the situation that diffusivity reduces
Under, the marginal portion of fabric can cause the problem of can not impregnating wet tissue composition, and this can give microorganism to provide growing environment, so as to
The reason for being contaminated as wet tissue.Therefore, during the wet tissue composition low using diffusivity prepares wet tissue, exist
The worries that the both sides of wet tissue fabric further set nozzle to produce, this will increase the consumption of wet tissue composition.
Criterion to the diffusivity of wet tissue composition is to be instilled in a diameter of 10cm the middle of wet tissue fabric
0.5ml or 1ml wet tissue composition, after placing 1 hour, the size of the spread diameter of measure.Now, 0.5ml is being instilled
Wet tissue composition in the case of, wet tissue composition diffusion diameter more than size average out to 3.0cm, instill 1ml feelings
Under condition, during more than average out to 6.0cm, when preparing wet tissue, wet tissue composition could be fully impregnated to the marginal portion of wet tissue,
Therefore, it may determine that the diffusivity of wet tissue composition is excellent based on the standard.
Thus, confirmed using the wet tissue composition of the 1~embodiment of embodiment 3 and comparative example in wet tissue fabric
Diffusivity.
0.5ml or 1ml wet tissue composition is instilled respectively be mainly used as wet tissue raw material, with 6:4 ratio mixing
In the non-woven fabrics for having staple fibre and polyethylene, and the diameter of absorption is determined, and the results are shown in table 6.
Table 6
As shown in above-mentioned table 6, it is known that, contain cetylpyridinium chloride compared to such as 12~comparative example of comparative example 21
Wet tissue composition, the of the invention of such as described 1~embodiment of embodiment 3 contain chlorination dococylpyridinium as main component
Range of scatter of the wet tissue composition in fabric it is wide.
In addition, the gross weight % for confirming chlorination dococylpyridinium and compound is higher, chlorination dococylpyridinium and
How much the diffusivity that the high content of compound can be decreases, but with identical weight % cetylpyridinium chloride
To replace the situation of chlorination dococylpyridinium to compare, it is thus identified that the diffusion of the wet tissue composition containing chlorination dococylpyridinium
Property is some higher.
Further, in the case of the wet tissue composition of 2~comparative example of comparative example 10, although the diffusivity in fabric
Height, but in the antibacterial activity result of the wet tissue composition in the experimental example 1, the antibacterial with can act as wet tissue composition is lived
The a reference value of property is low, it may thus be appreciated that being not suitable as wet tissue composition.
It follows that the present invention's contains diffusivity of the chlorination dococylpyridinium as the wet tissue composition of main component
It is excellent, so as to be readily applied to the preparation of wet tissue.
By the result of the experimental example 1 and experimental example 2, of the invention contains chlorination dococylpyridinium as master
The wet tissue composition of composition is wanted compared with the cetylpyridinium chloride primarily now used, because of the death rate of bacterium and in wet tissue face
Diffusivity in material is excellent, so that a kind of wet tissue composition that can substitute cetylpyridinium chloride.
Experimental example 3 is according to the confirmation of the diffusible antibacterial activity of wet tissue composition
Implement the diffusible antibacterial activity of the wet tissue composition according to 1~embodiment of above-described embodiment 3 and comparative example
Comparative experiments.
By the embodiment 1-2, embodiment 2-1 and embodiment 3-1 wet tissue composition and use cetylpyridinium chloride
Come replace the wet tissue composition of the comparative example 13 of the chlorination dococylpyridinium of embodiment, comparative example 20 and comparative example 21 respectively with
2.5 times or so of weight of fabric weight is poured on the wet tissue fabric of 5 foldings (with 6:4 ratio is mixed with staple fibre and gathered
The non-woven fabrics of ethene) middle body after, be placed above the article of about 5kg weight, placing 1 hour.Afterwards, first is utilized
And last confirms antimicrbial power.
Described first and last wet tissue fabric are put into the 100ml physiological saline by sterilizing so that wet
After towel composition is fully dissolved out, wet tissue composition using dissolution according to being tested with the above-mentioned identical method of experimental example 2,
So as to confirm the death rate of bacterium, if the death rate of bacterium is more than 99.9%, it is judged as with antibacterial activity, if less than
99.9%, then it is judged as no antibacterial activity, and the results are shown in table 7.
Table 7
As knowable to above-mentioned table 7, in the situation of above-described embodiment 1-2, embodiment 2-1 and embodiment 3-1 wet tissue composition
Under, in first of wet tissue fabric and last, antibacterial effect has been above a reference value that wet tissue composition can use,
On the other hand, as the wet tissue composition of comparative example 13, comparative example 20 and comparative example 21, make containing cetylpyridinium chloride
In the case of wet tissue composition for main component, it is thus identified that last antibacterial effect of wet tissue fabric is not above wet tissue
The a reference value that composition can use, it is possible thereby to be contemplated to the wet tissue composition of comparative example 13, comparative example 20 and comparative example 21
Diffusivity in wet tissue fabric is low, so as to fail thoroughly to be impregnated into last.
It follows that the present invention's contains chlorination dococylpyridinium and can be substituted as the wet tissue composition of main component
The wet tissue composition containing cetylpyridinium chloride primarily now used.
The preparation of the wet tissue of wet tissue composition of the preparation example 1 containing the present invention
The wet tissue composition of the 1~embodiment of embodiment 3 and comparative example is impregnated into the wet tissue fabric of 80 mesh respectively,
So as to prepare wet tissue product.
The confirmation of the antibacterial activity of the wet tissue of experimental example 4
Confirm antibacterial activity using the wet tissue prepared in above-mentioned preparation example 1.
1 above-mentioned wet tissue is put into the 100ml physiological saline by sterilizing, so that wet tissue composition is fully molten
After going out, the wet tissue composition using dissolution is according to being tested with the above-mentioned identical method of experimental example 2, so as to confirm bacterium
The death rate, if the death rate of bacterium be more than 99.9%, be judged as with antibacterial activity, if less than 99.9%, then sentence
Break as no antibacterial activity, and the results are shown in table 8.
Table 8
As knowable to above-mentioned table 8, in the case of the wet tissue prepared using above-described embodiment 1-3 wet tissue composition, to thin
The antibacterial effect of bacterium, fungi and Burkholderia has been above a reference value, on the other hand, as 1~comparative example of comparative example 8, only
Situation containing chlorination dococylpyridinium and a kind of compound or as comparative example 9 and comparative example 10, chlorination dodecyl
In the case of content of the content of pyridine and compound less than the present invention, for the antibacterial effect of bacterium, fungi and Burkholderia
Less than a reference value.In addition, the present invention's replaces chlorination dococylpyridinium of the invention containing cetylpyridinium chloride
In the case of the wet tissue composition of 12~comparative example of comparative example 21, it is known that be not above benchmark for the bacterium death rate of Burkholderia
Value.
It follows that by the use of the present invention to contain chlorination dococylpyridinium made as the wet tissue composition of main component
Standby wet tissue has excellent antibacterial activity.
The confirmation of the physical characteristic of the wet tissue of experimental example 5
Using the wet tissue prepared in above-mentioned preparation example 1 come confirm the adhesive band of wet tissue occur as and it is wet and slippery wait physics spy
Property.
Adhesive band occurs as in the case of, wet tissue is extracted with identical strength and speed, during extraction, to continuous
The number for extracting the situation of more than two out is determined, and the results are shown in table 9.
Table 9
As shown in above-mentioned table 9, it is thus identified that as the 1~embodiment of embodiment 3, using containing chlorination dodecyl
Pyridine contains chlorine as the wet tissue prepared by the wet tissue composition of main component with being utilized as 13~comparative example of comparative example 21
Change cetyl pyridinium to compare as the wet tissue prepared by the wet tissue composition of main component, produce adhesive band and occur as few.
In addition, wet and slippery sense for wet tissue and in the case of produce foam, contains chlorination dodecyl pyrrole using the present invention
Pyridine as the wet tissue prepared by the wet tissue composition of main component with by the use of containing cetylpyridinium chloride as main component
Wet tissue composition prepared by wet tissue compare, occur that wet and slippery situation is few, and the situation for producing foam is few.
It follows that the present invention's is made as the wet tissue composition of main component by the use of chlorination dococylpyridinium is contained
The excellent quality of standby wet tissue.
Claims (8)
1. a kind of improve the diffusible wet tissue composition in wet tissue fabric, it is characterised in that it is included：
A, chlorination dococylpyridinium；And
B, selected from caprylyl hydroxamic acid, xenyl hydroxamic acid, cinnamoyl hydroxamic acid, ethohexadiol, hexylene glycol, the third two
Alcohol, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, dehydroactic acid, anhydrous sodium acetate, propionic acid, sodium propionate, formic acid, formic acid
Sodium, hexamidine disalt, decoyl glycine, endecatylene acyl glycine, C12-C14 alkyl diamino ethyl glycines hydrogen chloride,
In the sub- second diaminourea glycine of lauryl two, lauryl aminopropyl glycine, tropolone and Chlorphenesin it is a kind of with
On compound.
2. diffusible wet tissue composition of the raising according to claim 1 in wet tissue fabric, it is characterised in that described
Wet tissue composition contains 0.01~30 weight % a, chlorination dococylpyridinium；And
0.001~40 weight % b, selected from caprylyl hydroxamic acid, xenyl hydroxamic acid, cinnamoyl hydroxamic acid, pungent
Glycol, hexylene glycol, propane diols, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, dehydroactic acid, anhydrous sodium acetate, propionic acid,
Sodium propionate, formic acid, sodium formate, hexamidine disalt, decoyl glycine, endecatylene acyl glycine, C12-C14 alkyl diaminourea second
The sub- second diaminourea glycine of base glycine hydrogen chloride, lauryl two, lauryl aminopropyl glycine, tropolone and chlorobenzene
The compound of one or more of sweet ether.
3. diffusible wet tissue composition of the raising according to claim 1 or 2 in wet tissue fabric, it is characterised in that
In the wet tissue composition, chlorination dococylpyridinium；And selected from caprylyl hydroxamic acid, xenyl hydroxamic acid, Chinese cassia tree
Acylhydroxamic acids, ethohexadiol, hexylene glycol, propane diols, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, dehydroactic acid, nothing
Water sodium acetate, propionic acid, sodium propionate, formic acid, sodium formate, hexamidine disalt, decoyl glycine, endecatylene acyl glycine, C12-
The sub- second diaminourea glycine of C14 alkyl diamino ethyl glycines hydrogen chloride, lauryl two, lauryl aminopropyl glycine, ring
The compound of one or more of heptantriene phenolic ketone and Chlorphenesin is with 1:10~10:1 part by weight mixing.
4. diffusible wet tissue composition of the raising according to claim 1 or 2 in wet tissue fabric, it is characterised in that
The compound is caprylyl hydroxamic acid, xenyl hydroxamic acid, cinnamoyl hydroxamic acid, ethohexadiol, hexylene glycol, the third two
Alcohol, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, dehydroactic acid, anhydrous sodium acetate, propionic acid, sodium propionate, formic acid and formic acid
Sodium.
5. diffusible wet tissue composition of the raising according to claim 4 in wet tissue fabric, it is characterised in that described
Compound is caprylyl hydroxamic acid, xenyl hydroxamic acid and cinnamoyl hydroxamic acid.
6. diffusible wet tissue composition of the raising according to claim 1 or 2 in wet tissue fabric, it is characterised in that
The wet tissue composition further contains NMF and pH adjusting agent.
7. diffusible wet tissue composition of the raising according to claim 1 or 2 in wet tissue fabric, it is characterised in that
The wet tissue composition is to aurococcus, Escherichia coli, Pseudomonas aeruginosa, Xi Shi enterobacterias, Brazilian aspergillus niger, white
Color candida albicans, soil mycobacterium and Burkholderia cepacia have sterilizing power.
8. the wet tissue containing the wet tissue composition described in claim 1 or 2.
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| KR1020170031327A KR101798978B1 (en) | 2016-04-12 | 2017-03-13 | Wet wipes composition comprising Laurylpyridinium chloride for enhancing of diffusivity in wet wipe's fabric and wet wipes including thereof |
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| CN109172408A (en) * | 2018-09-12 | 2019-01-11 | 南六企业（平湖）有限公司 | A kind of pure water wet tissue |
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| KR102027939B1 (en) * | 2019-01-04 | 2019-10-04 | 주식회사 에스앤지 | Cosmetic composition and preparation method of the same |
| KR102005266B1 (en) * | 2019-03-08 | 2019-07-31 | 주식회사 명진뉴텍 | Wet wipes composition comprising laurylpyridinium chloride and organic acid, polyhydric alcohol or mixtures thereof and wet wipes containing the same |
| KR102430588B1 (en) * | 2021-10-27 | 2022-08-08 | 주식회사 다인소재 | Antiseptic composition and Wet tissue comprising the same. |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109172408A (en) * | 2018-09-12 | 2019-01-11 | 南六企业（平湖）有限公司 | A kind of pure water wet tissue |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20170116942A (en) | 2017-10-20 |
| KR101798978B1 (en) | 2017-11-20 |
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