JP2006036763A - Water-in-oil emulsion composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a water-in-oil emulsion composition in which the constituent amphipathic lipid is stably emulsified with a low concentration of the surfactant, the constituent powder exhibits good stay on the skin and good water resistance and which gives excellent texture to the skin. <P>SOLUTION: The water-in-oil emulsion composition comprises 0.1 to 1 mass% (A) quaternary ammonium salt type cationic surfactant represented by formula (1) (wherein R<SP>1</SP>and R<SP>2</SP>are each independently a 16 to 22C hydrocarbon group; R<SP>3</SP>and R<SP>4</SP>are each independently a 1 to 3C alkyl or hydroxyalkyl group; and X is a salt-forming anion), (B) an amphipathic lipid, (C) a dihydric or trihydric alcohol, (D) a powder, and (E) water. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to an oil-in-water emulsified composition having excellent powder persistence and water resistance and excellent usability, and a method for producing the same.

  Oil-in-water emulsified cosmetics have a refreshing and smooth feeling of use, but the base is water-based, so it is easy to cause makeup collapse by sweating, and it is a powder for the purpose of feeling of use and UV protection. When the body component is used, it is difficult to maintain the effect by allowing the powder component to remain on the skin for a long time.

  On the other hand, in recent years, it has been shown that intercellular lipids present in the skin stratum corneum are deeply involved in retention of stratum corneum and barrier function. Therefore, in order to enhance the moisturizing effect, cosmetics containing amphiphilic lipids such as ceramide, which is a main component of intercellular lipids present in the skin stratum corneum, and similar substances have been proposed. However, these amphiphilic lipids have low solubility in water and remain solid up to a considerably high temperature, so that a large amount of surfactant is required especially for stable incorporation into an oil-in-water emulsion composition. The

  The human skin is usually covered with a weakly acidic sebum film, so that the pH of the skin can be controlled naturally against contact with an alkaline substance from the outside. For example, when washed with a fatty acid soap, the skin surface becomes weakly alkaline, but is naturally neutralized by free fatty acids from sebum. In addition, external preparations and cosmetics to be applied to the skin have a weak influence on the skin as much as possible, and are also preferable for people with sensitive skin. Therefore, the present inventors have studied to stably mix an intercellular lipid component with a small amount of surfactant in a weakly acidic cosmetic.

  Patent Document 1 discloses a stable emulsified composition by emulsifying an oil medium obtained by dissolving an amphiphilic lipid such as ceramide in a liquid oil having a melting point of less than 30 ° C. with an aqueous medium using a polyglycerol fatty acid ester. A method of obtaining an object is disclosed. However, in order to obtain a stable emulsion by this method, a large amount of polyglycerol fatty acid ester equivalent to that of the amphiphilic lipid is required, and in order to obtain a weakly acidic emulsion, an acid such as an organic acid is required. Substances must be added to adjust the pH.

Patent Document 2 describes an attempt to stabilize an amphiphilic lipid by using a nonionic surfactant and an ionic surfactant in combination. However, even in this combination, there is a problem that the amount of the surfactant to be used is large, and in the acidic region where the pH is 6 or less, the anionic surfactant becomes difficult to function as an emulsifier.
JP 2002-114631 A JP-A-4-193814

  The present invention is capable of stably emulsifying an oil phase containing an amphipathic lipid such as ceramide, which is generally difficult to mix in an aqueous medium, with a low-concentration surfactant, and the effect of the powder used in combination lasts for a long time. And it aims at providing the oil-in-water type emulsion composition excellent in the usability | use_condition, and its manufacturing method.

  The present inventor can stably emulsify the amphiphilic lipid with a low concentration of surfactant by combining the amphiphilic lipid with a specific cationic surfactant, divalent or trivalent alcohol and powder. The present inventors have found that an oil-in-water emulsified composition having excellent powder persistence and water resistance and excellent usability can be obtained.

The present invention includes the following components (A) to (E):
(A) The following general formula (1)

(In the formula, R ¹ and R ² each independently represent a hydrocarbon group having 16 to 22 carbon atoms, and R ³ and R ⁴ each independently represent an alkyl group or hydroxyalkyl group having 1 to 3 carbon atoms. , X represents a salt-forming anion)
A quaternary ammonium salt type cationic surfactant represented by 0.1-1% by mass,
(B) amphiphilic lipids,
(C) a divalent or trivalent alcohol,
(D) powder,
(E) An oil-in-water emulsion composition containing water is provided.

  The present invention also provides a quaternary ammonium salt type cationic surfactant represented by the general formula (1) and (C) a divalent or trivalent alcohol, and then (B) an amphiphilic lipid. An oily phase containing an aqueous medium, and then an aqueous medium and (D) a powder are added to provide a method for producing an oil-in-water emulsion composition.

  The oil-in-water emulsion composition of the present invention contains an amphipathic lipid such as ceramide, is excellent in emulsion stability during storage, and is excellent in use feeling. Furthermore, since the surfactant is in a low concentration, there is little irritation to the skin. Therefore, the oil-in-water emulsified composition of the present invention is useful as an external preparation or cosmetic, particularly a skin cosmetic, with less irritation to the skin.

  Moreover, the production method of the present invention is suitable for producing the oil-in-water emulsion composition, and the amphiphilic lipid can be stably emulsified with a small amount of a surfactant. This production method is advantageous in terms of productivity because a weakly acidic emulsion composition can be obtained without particularly adjusting the pH.

  The oil-in-water emulsion composition of the present invention is an aqueous continuous solution comprising (B) an oil phase containing amphiphilic lipids and (C) a divalent or trivalent alcohol (hereinafter referred to as polyhydric alcohols (C)). An oil-in-water emulsion composition in which the phase is emulsified with (A) a quaternary ammonium salt type cationic surfactant represented by the general formula (1) (hereinafter referred to as a cationic surfactant (A)) (D) containing powder.

  In the emulsified composition of the present invention, the cationic surfactant (A) and the amphiphilic lipid (B) associate with each other in an aqueous medium containing a polyhydric alcohol (C) to form a liquid crystal (or α-gel structure). It is considered that a thickened structure is formed. The thickening structure exhibits viscous behavior and can take a stable state against coalescence of oil droplets and creaming. Such a combination can form a highly stable liquid crystal structure even when the concentration of the cationic surfactant (A) is low, so that the amount of the surfactant used can be reduced. Here, since the thickened structure has optical anisotropy, it can be confirmed with a polarizing microscope or the like.

  The emulsified composition of the present invention preferably exhibits thixotropic properties, and the thickened structure maintains a stable liquid crystal structure in a stationary state, but the liquid crystal structure is easily broken at the time of application, and the application part is thin and thin. Since it spreads evenly, a refreshing and fresh feeling is obtained.

  The cationic surfactant (A) used in the present invention is represented by the general formula (1), and has a quaternary ammonium salt structure having two long-chain hydrocarbon groups in one molecule. Cationic surfactant.

In the formula, the hydrocarbon group represented by R ¹ and R ² is preferably an alkyl group or alkenyl group having 16 to 22 carbon atoms, and examples thereof include a cetyl group, a stearyl group, an aralkyl group, and a behenyl group. Examples of the hydrocarbon group represented by R ³ and R ⁴ include a methyl group, an ethyl group, and a propyl group.
Examples of the salt-forming anion represented by X include halogen ions, phosphate ions, acetate ions, lactate ions, monoalkyl sulfate ions, and the like.

  Specific examples of the cationic surfactant (A) include dicetyldimethylammonium chloride, distearyldimethylammonium chloride, diaralkyldimethylammonium chloride, dibehenyldimethylammonium chloride, and the like. Of these, dicetyldimethylammonium chloride and distearyldimethylammonium chloride are also commercially available, and Varisoft TA-432CG, Varisoft TA-100 (Goldschmidt), Quartamin D-86P (Kao), etc. are used. be able to.

  Of these cationic surfactants, dicetyldimethylammonium chloride, distearyldimethylammonium chloride and the like are preferable from the viewpoint of affinity for the skin.

  The content of the cationic surfactant (A) is the total composition of the oil-in-water emulsion composition from the viewpoint of forming a suitable liquid crystal structure together with the amphiphilic lipid (B) and polyhydric alcohol (C) described later. It is 0.1-1 mass% in inside, Preferably it is 0.5-1 mass%.

  The amphiphilic lipid (B) is a substance that has both a hydrophilic part and a hydrophobic part in the molecule and is solid at 25 ° C. Examples of the amphiphilic lipid (B) include cholesterols such as cholesterol, cholesterol fatty acid esters, and cholesterol sulfates; higher fatty acids such as stearic acid and palmitic acid; cetyl alcohol, stearyl alcohol, behenyl alcohol, batyl alcohol, and chimyl alcohol. Higher alcohols; glycerin fatty acid esters and the like.

  In addition, amide compounds represented by the following general formulas (2) to (4) may be mentioned as amphiphilic lipids that are particularly excellent in skin barrier function and moisturizing function and have an excellent effect of improving skin roughness.

(In the formula, R ¹¹ is a hydrocarbon group having 8 to 50 carbon atoms which may be substituted with one or more hydroxyl groups, or a group represented by R ¹³ —COO—R ¹⁴ — (R ¹³ is a group having 8 to 30 hydrocarbon group, R ¹⁴ is a divalent hydrocarbon group having 8 to 40 carbon atoms which may be substituted with one or more hydroxyl groups, and R ¹² is substituted with one or more hydroxyl groups. May represent a hydrocarbon group having 8 to 50 carbon atoms)

Wherein R ¹⁵ represents a hydrocarbon group having 7 to 25 carbon atoms which may be substituted with one or more hydroxyl groups, and R ¹⁶ represents 8 to carbon atoms which may be substituted with one or more hydroxyl groups. 26 represents a hydrocarbon group or an alkoxy group, R ¹⁷ represents a hydrogen atom, a 2-hydroxyethyl group or a 2,3-dihydroxypropyl group, and Y represents a hydrogen atom or a hydroxyl group)

(In the formula, each R ¹⁸ independently represents a hydrocarbon group having 1 to 22 carbon atoms which may be substituted with a hydroxyl group and / or an alkoxy group, and each R ¹⁹ independently represents 1 to 1 carbon atoms. 12 represents a divalent hydrocarbon group, and R ²⁰ represents a divalent hydrocarbon group having 1 to 42 carbon atoms)

In the general formula (2), R ¹¹ is preferably a hydrocarbon group having 8 to 30 carbon atoms which may be substituted with one or more hydroxyl groups, or a group represented by R ¹³ —COO—R ¹⁴ —. . Here, R ¹³ is preferably a hydrocarbon group having 8 to 30 carbon atoms, and R ¹⁴ is preferably a divalent hydrocarbon group having 8 to 30 carbon atoms which may be substituted with one or more hydroxyl groups. R ¹² is preferably a hydrocarbon group having 8 to 30 carbon atoms which may be substituted with one or more hydroxyl groups. In particular, R ¹¹ and R ¹³ are preferably linear alkyl groups having 8 to 30 carbon atoms, and R ¹⁴ is preferably a linear alkylene group having 8 to 30 carbon atoms.

  Specific examples of the amide compound represented by the general formula (2) include Robson KJ et al., J. Lipid Res., 35, 2060 (1994) and Wertz PW et al., J. Lipid Res., Examples include ceramides of types 1 to 7 described in 24,759 (1983). These can be produced by extraction and reaction modification from animals and plants, or total synthesis. Examples of commercially available ceramides include ceramide III, ceramide IIIB, ceramide IIIA, ceramide IV, phytoceramide I (degussa), ceramide II (cederma), ceramide TIC-001 (takasago fragrance). It is done.

In the general formula (3), R ¹⁵ is preferably a hydrocarbon group having 14 to 22 carbon atoms which may be substituted with one or more hydroxyl groups, and particularly preferably a linear alkyl group. Furthermore, a pentadecyl group and a trihydroxypentadecyl group are more preferable.

R ¹⁶ is preferably a linear alkyl group or alkoxy group having 8 to 24 carbon atoms, and more preferably a nonyl group or a hexadecyloxy group.

Regarding the combination of R ¹⁶ and R ¹⁷ , when R ¹⁷ is a hydrogen atom or a 2-hydroxyethyl group, R ¹⁶ is preferably a straight-chain alkoxy group, and when R ¹⁷ is a 2,3-dihydroxypropyl group. In R, R ¹⁶ is preferably a linear alkyl group.

Regarding the combination of Y and R ¹⁷ , when R ¹⁷ is a hydrogen atom or a 2-hydroxyethyl group, Y is preferably a hydroxyl group, and when R ¹⁷ is a 2,3-dihydroxypropyl group, Y is A hydrogen atom is preferred.

  Specific examples of the amide compound represented by the general formula (3) include compounds represented by the following formulas (5), (6) and (7).

  The amide compound of formula (3) can be obtained by the method described in JP-A-62-228048, for example, acylating a reaction product obtained from glycidyl ether and ethanolamine, and then selectively hydrolyzing the ester group. It can manufacture by the method to do.

  Of these, the amide compound represented by the formula (5) is preferable, and Sofcare Ceramide SL-E (N- (3-hexadecyloxy-2-hydroxypropyl) -N-2-hydroxyethylhexadecanamide, Kao)).

In the amide compound represented by the general formula (4), R ¹⁸ may have 1 to 22 carbon atoms which may be substituted with 1 to 3 groups selected from a hydroxyl group and an alkoxy group having 1 to 6 carbon atoms. Are preferably substituted with a hydroxyl group and an alkoxy group at the same time.

For example, an alkyl group having 1 to 18 carbon atoms, a mono- or di-hydroxyalkyl group having 1 to 18 carbon atoms, an alkyl group having 1 to 18 carbon atoms substituted by an alkoxy group having 1 to 6 carbon atoms, a hydroxyl group and a carbon number The C1-C18 alkyl group which the 1-6 alkoxy group substituted is preferable. In particular, an alkyl group having 1 to 18 carbon atoms, a mono- or dihydroxyalkyl group having 2 to 12 carbon atoms, an alkyl group having 2 to 12 carbon atoms substituted by an alkoxy group having 1 to 6 carbon atoms, a hydroxyl group and carbon A C2-C12 alkyl group substituted by a C1-C6 alkoxy group is more preferred. Of these, R ¹⁸ is more preferably a 2-hydroxyethyl group, a methyl group, a dodecyl group, or a 2-methoxyethyl group.

R ¹⁹ is preferably a linear or branched alkylene group having 1 to 12 carbon atoms, particularly a linear or branched alkylene group having 2 to 6 carbon atoms. Furthermore, an ethylene group and a trimethylene group are more preferable.

R ²⁰ is preferably a divalent hydrocarbon group having 2 to 34 carbon atoms, more preferably an alkylene group having 2 to 34 carbon atoms or an alkenylene group having 1 to 4 double bonds, particularly 2 to 2 carbon atoms. Twenty-four linear or branched alkylene groups or alkenylene groups having 1 to 4 double bonds are preferred. Of these, 7,12-dimethyloctadecamethylene group, 7,12-dimethyl-7,11-octadecadienylene group, octadecamethylene group, octamethylene group, decamethylene group, undecamethylene group, tridecamethylene Groups are more preferred.

As the amide compound represented by the general formula (4), a compound in which R ¹⁸ , R ¹⁹ and R ²⁰ are each combined with groups in the above-described more preferable range is preferable.

  The amide compound of the general formula (4) is, for example, a corresponding dicarboxylic acid or a reactive derivative thereof (ester, acid halide, acid anhydride, etc.) as described in International Publication No. 00/61097 pamphlet or the like. And an amine can be condensed efficiently.

  The amphiphilic lipid (B) used in the oil-in-water emulsion composition of the present invention is particularly represented by the following formulas (8) to (14) belonging to the amide compound represented by the general formula (4). Are particularly preferred.

  (B) The content of the amphiphilic lipid is preferably 0.1% by mass or more in the total composition of the oil-in-water emulsion composition in order to sufficiently exhibit the barrier function and moisturizing function for the skin. Considering the balance with storage stability, it is more preferably 0.1 to 20% by mass, particularly 0.1 to 10% by mass in the total composition.

  In addition, the mass ratio (A: B) of the cationic surfactant (A) to the amphiphilic lipid (B) is 10: 1 to 1:20 from the viewpoint of expression of effects on the skin and formation of a suitable liquid crystal structure. Further, it is preferably 10: 1 to 1:10.

  In the present invention, the divalent or trivalent alcohol of component (C) is preferably one that can dissolve and disperse the cationic surfactant described above when blended in an emulsified cosmetic. A liquid crystal structure suitable for a low concentration of the cationic surfactant by mixing the cationic surfactant (A) with the polyhydric alcohol (C) and then mixing with the oil component containing the amphiphilic lipid (B). The body can be formed.

  Examples of such polyhydric alcohols (C) include ethylene glycol, polyethylene glycol (average molecular weight 200 to 400), propylene glycol, dipropylene glycol, 1,3-butanediol, glycerin, and polyglycerin (degree of polymerization 2 to 5). ) And the like. Of these, glycerin and ethylene glycol are particularly preferred.

  As the polyhydric alcohol (C), one or more kinds can be used, and the content thereof has a good feeling of use, forms a suitable liquid crystal structure, and obtains a stable emulsion. It is preferable that it is 5-40 mass% in the whole composition of an oil-type emulsion composition, especially 5-20 mass%.

The powder (D) used in the present invention is used in cosmetics for the purpose of improving the feeling of application and feeling of use and changing the appearance color. It can be classified into hydrophilic powder and hydrophobic powder. Examples of the hydrophilic powder include inorganic powder, natural fiber powder, starch, organic dye, pearlescent pigment, hydrophilic synthetic resin powder, and the like.
Inorganic powders include kaolin, phlogopite, aluminum silicate / magnesium, calcium silicate, synthetic aluminum silicate, sericite, talc, natural aluminum silicate, pyroferrite clay, bentonite, mica, anhydrous silicic acid, anhydrous Aluminum silicate, montmorillonite, vermiculite, hectorite, zeolite, hydrite, yellow iron oxide, ocher, black iron oxide, bengara, black titanium oxide, zinc oxide, aluminum oxide, aluminum cobalt oxide, chromium oxide, zirconium oxide, titanium dioxide , Titanium oxide sol, Sintered iron oxide / titanium dioxide, Cerium oxide, Magnesium oxide, Chromium hydroxide, Titanium / titanium dioxide sintered product, Cobalt titanate, Gunjo, Gunjo violet, Gunjo pink, Conju, Ma Gun Violet, Carbon Black, Calcium Carbonate, Magnesium Carbonate, Barium Sulfate, Bismuth Oxychloride, Calamine, Epoxy Treated Aluminum, Acrylic Resin Coated Aluminum Powder, Aluminum Powder, Copper Powder, Gold Colloid, Gold Foil, Sodium Rosinate Treated Magnesium Oxide, Silica Examples thereof include magnesium oxide, boron nitride, and the like, and two or more kinds of these composite powders and organic-inorganic composite powders such as titanium oxide-coated nylon powder.
Among these inorganic powders, titanium dioxide, zinc oxide, iron oxide and the like can be used as a UV scattering agent as described later.

Examples of the natural fiber powder include silk, wool, and cellulose, and examples of the starch include rice, corn, and potato.
Examples of organic dyes include carbon black, ultramarine blue, bitumen, tar dyes, and lakes, and examples of pearlescent pigments include mica titanium, iron oxide-coated mica titanium, titanium dioxide-coated mica, and fish scale foil.
Examples of the hydrophilic synthetic resin powder include (meth) acrylic ester resin powder containing (meth) acrylic acid or a salt thereof as a constituent monomer. Specific examples include crosslinked resin powders such as lauryl methacrylate / ethylene glycol / methacrylic acid / sodium methacrylate copolymer and butyl acrylate / diethyl methacrylate / sodium methacrylate copolymer.

  Also, as hydrophobic powder, polyamide resin powder (nylon powder), porous cellulose powder, porous nylon powder, polyethylene powder, tetrafluoropolyethylene powder, cross-linked polystyrene powder, silicone resin powder, cross-linked Examples thereof include synthetic resin powders such as type silicone powder, reticulated methylpolysiloxane powder, and polymethylmethacrylate powder.

Moreover, what hydrophobized the said hydrophilic powder is also contained. As a method for hydrophobizing, for example, an oil or fat treatment method for making a powder lipophilic by causing fat or oil to be adsorbed on the powder surface or by using a functional group such as a hydroxyl group to cause esterification or etherification. Metal soap treatment method using fatty acid zinc salt, magnesium salt or aluminum salt; silicone treatment method using silicone compound such as dimethylsiloxane or methylhydrogensiloxane; method of treating with fluorine compound having perfluoroalkyl group, etc. Can be mentioned.
The amount of hydrophobization treatment is not limited as long as the powder is sufficiently hydrophobic when blended in a cosmetic, and is preferably 1% by mass or more with respect to the amount of hydrophilic powder serving as a base material. .

In addition, the powder of component (D) has an average particle diameter of 0.01 to 500 μm, but forms a uniform coating film containing the powder on the skin, and a high water resistance effect is obtained. And it is preferable at the point that a usability | use_condition is favorable.
One or more components (D) can be used, have a good feeling of use, form a suitable liquid crystal structure, and obtain a stable emulsion. It is preferable to contain 40% by mass, particularly 1 to 30% by mass, because sufficient water resistance and durability can be obtained, and stability and usability are excellent.

The content of water (E) that forms the aqueous phase continuous phase of the oil-in-water emulsion composition of the present invention is usually preferably 10 to 90% by mass, particularly preferably 40 to 90% by mass in the total composition.
As an aqueous phase component other than water, water-soluble components other than the polyhydric alcohols (C) such as ethyl alcohol, various water-soluble medicinal agents, antioxidants, preservatives, bactericides, salts, amino acids, saccharides, Chelating agents, thickeners, pigments, fragrances and the like can be included.

  The oil-in-water emulsion composition of the present invention includes, in addition to the amphiphilic lipid (B), synthetic, naturally-derived oily components such as hydrocarbon oils and ester oils that are liquid, semisolid or solid at 25 ° C. , Ether oil, silicone oil, fluorine oil and the like.

  Examples of liquid oil include vegetable oil such as jojoba oil; animal oil such as liquid lanolin; hydrocarbon oil such as liquid paraffin and squalane; diisostearyl malate, octyldodecyl lactate, isotridecyl isononanoate, isopropyl isostearate, octyl myristate Ester oils such as dodecyl and neopentyl glycol dicaprate; glycerin derivatives; amino acid derivatives; silicone oils such as dimethylpolysiloxane, dimethylcyclopolysiloxane, methylphenylpolysiloxane, methylhydrogenpolysiloxane, higher alcohol-modified organopolysiloxane; fluoro Fluorine oils such as polyether and perfluoroalkyl ether silicone are exemplified.

  Examples of solid or semi-solid oily components include vegetable waxes such as jojoba wax; alkyl glyceryl ethers such as glycerin monostearyl ether and glycerin monocetyl ether; petrolatum, lanolin, ceresin, microcrystalline wax, carnauba wax, candelilla wax, etc. Waxes.

  The content of the oil component other than these components (B) is usually 0.1 to 30% by mass, particularly 1 to 20% by mass in the whole composition.

  Moreover, when setting it as the emulsion composition which intends ultraviolet (UV) care cosmetics, the UV protective agent called a UV absorber or a UV scattering agent can be contained. As the UV absorber, compounds such as paramethoxycinnamic acid, benzophenone, urocanic acid, paraaminobenzoic acid, salicylic acid, benzoylmethane, triazine, anthranilic acid, and the like can be used. Powders such as titanium dioxide, zinc oxide, and iron oxide can be used.

  The content of such a UV protective agent is usually 1 to 40% by mass, preferably 1 to 20% by mass in the whole composition.

  Since such UV care cosmetics have high water resistance and are not easily removed by sweat or water, the UV protection effect has good durability while being an oil-in-water emulsion composition.

  The oil-in-water emulsion composition of the present invention is separately mixed with, for example, a first step of adding at least one cationic surfactant (A) to at least one polyhydric alcohol (C). A second step of adding an oil phase containing the amphiphilic lipid (B) placed to the mixture obtained in the first step, and a third step of adding an aqueous medium to the mixture obtained in the second step. And the fourth step of adding the powder (D) to the mixture obtained in the third step.

  After mixing the mixture obtained by adding the cationic surfactant (A) to the polyhydric alcohols (C) such as glycerin and the oil phase containing the amphiphilic lipid (B), aqueous components other than the alcohols By emulsifying by adding to the aqueous phase containing, a stable emulsified state is obtained without causing separation of the oil phase containing the amphiphilic lipid.

  By producing an oil-in-water emulsion composition by such a procedure, a cationic surfactant and an amphiphilic lipid form a liquid crystal structure in a polyhydric alcohol. In one, it can be stable against creaming. Here, when the amphiphilic lipid (B) is mixed with other components such as an oily component, it may be heated as necessary in order to improve the solubility or dispersibility.

  The oil-in-water emulsified composition of the present invention has an emulsion or cream-like appearance, and the viscosity at 25 ° C. is preferably about 1,000 to 100,000 mPa · s. The viscosity can be measured using a B-type viscometer.

  The oil-in-water emulsion composition of the present invention is preferably weakly acidic, specifically having a pH of 4 or more and less than 7, from the viewpoint of irritation to the skin and feeling of use. The pH of the composition is measured with a pH meter at 25 ° C. while keeping the stock solution.

  In the present invention, by combining the above components (A), (B), (C), (D) and (E), the pH is adjusted to acidic by adding a pH adjusting agent such as acid or alkali. Even if not, a weakly acidic emulsion composition can be obtained.

  The oil-in-water emulsified composition of the present invention is useful as an external preparation or a cosmetic, particularly a skin cosmetic, and depending on its use, any agent such as a lotion, gel, cream, UV care cosmetic, aerosol foam, etc. Can be a mold.

Examples 1-2 and Comparative Example 1
Oil-in-water emulsified cosmetics (UV care cosmetics) having the compositions shown in Table 1 were produced and evaluated for use feeling, durability of effects (water resistance of UV protection effect, durability of smooth feeling), and stability. The results are also shown in Table 1.
In addition, pH of each cosmetics was measured using the pH meter (F-22) made from HORIBA in 25 degreeC with the undiluted | stock solution.

(Manufacturing method)
(1) Examples 1 and 2:
Components (1) to (4) were uniformly dissolved and dispersed at 80 ° C. to obtain an oil phase. Separately, component (8) was added to component (9), dissolved uniformly at 80 ° C., and the above oil phase was added while maintaining the temperature. Furthermore, the water phase of component (10)-(11) was added, and it emulsified using the homogenizer, hold | maintaining at 80 degreeC, and obtained the emulsion. Thereafter, in Example 1, the powder (14) was dispersed in a part of purified water, and in Example 2, the powder (13) was dispersed in the component (5) and added to the emulsion. Furthermore, component (12) was added, and it cooled to room temperature (25 degreeC), stirring, and obtained UV care cosmetics.
(2) Comparative Example 1:
Components (1) to (4), (6) and (7) were uniformly dissolved and dispersed at 80 ° C. to obtain an oil phase. The aqueous phase of components (9) to (11) was added thereto, and the mixture was emulsified using a homogenizer while maintaining at 80 ° C. to obtain an emulsion. Thereafter, the powder (14) was dispersed in a part of purified water and added to the emulsion. Furthermore, component (12) was added, and it cooled to room temperature (25 degreeC), stirring, and obtained UV care cosmetics.

(Evaluation methods)
(1) Feeling of use:
Ten professional panelists sensoryly evaluate the feeling of use when using each cosmetic (comprehensive evaluation of moistness, freshness, good penetration, no stickiness, and nodding) Judged by criteria.
A: Seven or more people evaluated it as good (good).
(Triangle | delta): Four to six persons evaluated it as favorable (good).
X: Three or less evaluated as good (good).

(2) Sustainability of effects:
(2-1) Water resistance of UV protection effect (Examples 1 and 2 and Comparative Example 1):
Each cosmetic is applied (2 μL / cm ² ) on the surface of a quartz plate with tape (3 MBlenderm), and the SPF initial value is measured with an SPF analyzer. The coated quartz plate is immersed in a water bath for 40 minutes with stirring and then dried well, and then the SPF value after water bath is measured. The water resistance was evaluated by the value of SPF value after water bath / initial SPF value × 100 (%).
○: 90% or more.
Δ: 60% or more and less than 90%.
X: Less than 60%.

(2-2) Smooth feeling (Examples 3 to 7 and Comparative Example 2):
Ten professional panelists performed sensory evaluation on the smooth feeling after 3 hours from the use of each cosmetic, and judged according to the following criteria.
A: Seven or more people evaluated it as good (good).
(Triangle | delta): Four to six persons evaluated it as favorable (good).
X: Three or less evaluated as good (good).

(3) Stability:
After each cosmetic was stored at 50 ° C. for 1 week, the appearance was visually evaluated according to the following criteria.
A: Good.
○: Slightly uneven.
Δ: Slight aggregation / sedimentation is observed.
X: Aggregation and sedimentation are clearly recognized.

Examples 3 to 7 and Comparative Example 2
Oil-in-water emulsified cosmetics having the compositions shown in Table 2 were produced. About the obtained cosmetics, it measured the pH similarly to Examples 1-2, and evaluated the usability | use_condition, the sustainability of the effect (sustainability of a smooth feeling), and stability. The results are also shown in Table 2. In Table 2, * 1, * 2 and * 3 are the same as Table 1.

(Manufacturing method)
(1) Examples 3-7:
Components (1) to (5) were uniformly dissolved and dispersed at 80 ° C. to obtain an oil phase. Separately, component (8) was added to component (9), dissolved uniformly at 80 ° C., and the above oil phase was added while maintaining the temperature. Furthermore, the water phase of component (10)-(11) was added, and it emulsified using the homogenizer, hold | maintaining at 80 degreeC, and obtained the emulsion. Thereafter, in Examples 3 and 4, the powder is dispersed in component (5), in Example 5, the powder is dispersed in component (13), and in Examples 6 and 7, the powder is dispersed in a portion of purified water. And added to the emulsion. Furthermore, component (12) was added, and it cooled to room temperature (25 degreeC), stirring, and obtained emulsified cosmetics.
(2) Comparative Example 2:
Components (1) to (4), (6) and (7) were uniformly dissolved and dispersed at 80 ° C. to obtain an oil phase. The aqueous phase of components (9) to (11) was added thereto, and the mixture was emulsified using a homogenizer while maintaining at 80 ° C. to obtain an emulsion. Thereafter, the powder was dispersed in component (5) and added to the emulsion. Furthermore, component (12) was added, and it cooled to room temperature (25 degreeC), stirring, and obtained emulsified cosmetics.

Claims (4)

The following components (A) to (E):
(A) The following general formula (1)
(In the formula, R ¹ and R ² each independently represent a hydrocarbon group having 16 to 22 carbon atoms, and R ³ and R ⁴ each independently represent an alkyl group or hydroxyalkyl group having 1 to 3 carbon atoms. , X represents a salt-forming anion)
A quaternary ammonium salt type cationic surfactant represented by 0.1-1% by mass,
(B) amphiphilic lipids,
(C) a divalent or trivalent alcohol,
(D) powder,
(E) An oil-in-water emulsion composition containing water.   (D) The oil-in-water emulsion composition of Claim 1 which contains 0.5-40 mass% of powder.   The oil-in-water emulsion composition according to claim 1 or 2, wherein the pH is 4 or more and less than 7. (A) The following general formula (1)
(In the formula, R ¹ and R ² each independently represent a hydrocarbon group having 16 to 22 carbon atoms, and R ³ and R ⁴ each independently represent an alkyl group or hydroxyalkyl group having 1 to 3 carbon atoms. , X represents a salt-forming anion)
And (C) a divalent or trivalent alcohol, and (B) an oil phase containing an amphiphilic lipid is added, and then an aqueous medium And (D) A method for producing an oil-in-water emulsion composition in which powder is added.