JP2005534330A5 - - Google Patents
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- Publication number
- JP2005534330A5 JP2005534330A5 JP2004526896A JP2004526896A JP2005534330A5 JP 2005534330 A5 JP2005534330 A5 JP 2005534330A5 JP 2004526896 A JP2004526896 A JP 2004526896A JP 2004526896 A JP2004526896 A JP 2004526896A JP 2005534330 A5 JP2005534330 A5 JP 2005534330A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- biologically active
- active peptide
- albumin
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 31
- 102000004169 proteins and genes Human genes 0.000 claims 31
- 108090000623 proteins and genes Proteins 0.000 claims 31
- 238000000034 method Methods 0.000 claims 21
- 108010005939 Ciliary Neurotrophic Factor Proteins 0.000 claims 17
- 102100031614 Ciliary neurotrophic factor Human genes 0.000 claims 17
- 108020001507 fusion proteins Proteins 0.000 claims 16
- 102000037865 fusion proteins Human genes 0.000 claims 16
- 108010088751 Albumins Proteins 0.000 claims 11
- 102000009027 Albumins Human genes 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 11
- 239000012634 fragment Substances 0.000 claims 10
- 102000005962 receptors Human genes 0.000 claims 6
- 108020003175 receptors Proteins 0.000 claims 6
- 241000124008 Mammalia Species 0.000 claims 5
- 210000004962 mammalian cell Anatomy 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 230000004927 fusion Effects 0.000 claims 3
- 210000005260 human cell Anatomy 0.000 claims 3
- 102000016989 Ciliary Neurotrophic Factor Receptor Human genes 0.000 claims 2
- 108010000063 Ciliary Neurotrophic Factor Receptor Proteins 0.000 claims 2
- 208000008589 Obesity Diseases 0.000 claims 2
- 230000003213 activating effect Effects 0.000 claims 2
- 230000008499 blood brain barrier function Effects 0.000 claims 2
- 210000001218 blood-brain barrier Anatomy 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 238000001727 in vivo Methods 0.000 claims 2
- 235000020824 obesity Nutrition 0.000 claims 2
- 101710153593 Albumin A Proteins 0.000 claims 1
- 206010019233 Headaches Diseases 0.000 claims 1
- 206010060378 Hyperinsulinaemia Diseases 0.000 claims 1
- 206010028813 Nausea Diseases 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 108010014210 axokine Proteins 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 231100000869 headache Toxicity 0.000 claims 1
- 201000001421 hyperglycemia Diseases 0.000 claims 1
- 230000003451 hyperinsulinaemic effect Effects 0.000 claims 1
- 201000008980 hyperinsulinism Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000008693 nausea Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40183302P | 2002-08-07 | 2002-08-07 | |
| PCT/EP2003/008710 WO2004015113A2 (en) | 2002-08-07 | 2003-08-06 | Albumin-fused ciliary neurotrophic factor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010089560A Division JP2010213707A (ja) | 2002-08-07 | 2010-04-08 | アルブミン融合繊毛様神経栄養因子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005534330A JP2005534330A (ja) | 2005-11-17 |
| JP2005534330A5 true JP2005534330A5 (https=) | 2006-08-24 |
Family
ID=31715745
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004526896A Pending JP2005534330A (ja) | 2002-08-07 | 2003-08-06 | アルブミン融合繊毛様神経栄養因子 |
| JP2010089560A Withdrawn JP2010213707A (ja) | 2002-08-07 | 2010-04-08 | アルブミン融合繊毛様神経栄養因子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010089560A Withdrawn JP2010213707A (ja) | 2002-08-07 | 2010-04-08 | アルブミン融合繊毛様神経栄養因子 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1529108A2 (https=) |
| JP (2) | JP2005534330A (https=) |
| KR (1) | KR20050065519A (https=) |
| AU (1) | AU2003271043A1 (https=) |
| CA (1) | CA2496002A1 (https=) |
| WO (1) | WO2004015113A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0329681D0 (en) | 2003-12-23 | 2004-01-28 | Delta Biotechnology Ltd | Gene expression technique |
| GB0329722D0 (en) | 2003-12-23 | 2004-01-28 | Delta Biotechnology Ltd | Modified plasmid and use thereof |
| DK2330200T3 (en) | 2004-12-23 | 2017-07-24 | Albumedix As | GENE EXPRESSION TECHNIQUE |
| CN102462662A (zh) * | 2010-08-16 | 2012-05-23 | 重庆富进生物医药有限公司 | 脂质体包裹重组人睫状神经营养因子 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2719593B1 (fr) * | 1994-05-06 | 1996-05-31 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur préparation et composition pharmaceutique les contenant. |
| GB9526733D0 (en) * | 1995-12-30 | 1996-02-28 | Delta Biotechnology Ltd | Fusion proteins |
| EP2206720A1 (en) * | 2000-04-12 | 2010-07-14 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US6927040B2 (en) * | 2000-06-30 | 2005-08-09 | Zymogenetics, Inc. | Interferon-like protein Zcyto21 |
-
2003
- 2003-08-06 EP EP03750409A patent/EP1529108A2/en not_active Ceased
- 2003-08-06 AU AU2003271043A patent/AU2003271043A1/en not_active Abandoned
- 2003-08-06 KR KR1020057002155A patent/KR20050065519A/ko not_active Ceased
- 2003-08-06 JP JP2004526896A patent/JP2005534330A/ja active Pending
- 2003-08-06 CA CA002496002A patent/CA2496002A1/en not_active Abandoned
- 2003-08-06 WO PCT/EP2003/008710 patent/WO2004015113A2/en not_active Ceased
-
2010
- 2010-04-08 JP JP2010089560A patent/JP2010213707A/ja not_active Withdrawn
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