JP2005532262A5 - - Google Patents

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Publication number
JP2005532262A5
JP2005532262A5 JP2003565315A JP2003565315A JP2005532262A5 JP 2005532262 A5 JP2005532262 A5 JP 2005532262A5 JP 2003565315 A JP2003565315 A JP 2003565315A JP 2003565315 A JP2003565315 A JP 2003565315A JP 2005532262 A5 JP2005532262 A5 JP 2005532262A5
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JP
Japan
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optionally substituted
ion
tri
salt
fluorobenzyl
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JP2003565315A
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English (en)
Japanese (ja)
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JP2005532262A (ja
JP4530665B2 (ja
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Priority claimed from PCT/US2003/003740 external-priority patent/WO2003065882A2/en
Publication of JP2005532262A publication Critical patent/JP2005532262A/ja
Publication of JP2005532262A5 publication Critical patent/JP2005532262A5/ja
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Publication of JP4530665B2 publication Critical patent/JP4530665B2/ja
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JP2003565315A 2002-02-06 2003-02-06 放射性標識された親油性の塩を使用することによる、ミトコンドリアのための非浸襲性の画像診断技術 Expired - Fee Related JP4530665B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35456302P 2002-02-06 2002-02-06
PCT/US2003/003740 WO2003065882A2 (en) 2002-02-06 2003-02-06 Non-invasive diagnostic imaging technology for mitochondria using radiolabeled lipophilic salts

Publications (3)

Publication Number Publication Date
JP2005532262A JP2005532262A (ja) 2005-10-27
JP2005532262A5 true JP2005532262A5 (https=) 2006-01-05
JP4530665B2 JP4530665B2 (ja) 2010-08-25

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ID=27734391

Family Applications (1)

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JP2003565315A Expired - Fee Related JP4530665B2 (ja) 2002-02-06 2003-02-06 放射性標識された親油性の塩を使用することによる、ミトコンドリアのための非浸襲性の画像診断技術

Country Status (9)

Country Link
US (2) US8524193B2 (https=)
EP (1) EP1474177A4 (https=)
JP (1) JP4530665B2 (https=)
CN (2) CN101838289A (https=)
AU (1) AU2003217349B2 (https=)
CA (1) CA2474142C (https=)
NZ (1) NZ534496A (https=)
TW (1) TWI266634B (https=)
WO (1) WO2003065882A2 (https=)

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US8257680B1 (en) 2004-02-24 2012-09-04 The General Hospital Corporation Catalytic radiofluorination
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AU2011203177B2 (en) * 2004-02-24 2012-04-26 The General Hospital Corporation Catalytic radiofluorination
US7485283B2 (en) * 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
US7738096B2 (en) 2004-10-21 2010-06-15 University Of Georgia Research Foundation, Inc. Surface enhanced Raman spectroscopy (SERS) systems, substrates, fabrication thereof, and methods of use thereof
JP2006315958A (ja) * 2005-05-10 2006-11-24 Nihon Medi Physics Co Ltd 放射性ハロゲン標識有機化合物の製造方法
US7824659B2 (en) 2005-08-10 2010-11-02 Lantheus Medical Imaging, Inc. Methods of making radiolabeled tracers and precursors thereof
WO2008015392A1 (en) 2006-08-03 2008-02-07 Hammersmith Imanet Limited Fluoride drying method
WO2008098304A1 (en) * 2007-02-16 2008-08-21 The University Of Sydney Carborane-phosphonium compounds and their use in boron neutron capture therapy and imaging
EP1990310A1 (en) * 2007-04-23 2008-11-12 Trasis S.A. Method for the preparation of reactive 18F fluoride, and for the labeling of radiotracers, using a modified non-ionic solid support and without any evaporation step
EP2164524B1 (en) * 2007-05-30 2013-08-07 Children's Medical Center Corporation Fluorine-18 labeled rhodamine derivatives for myocardial perfusion imaging with positron emission tomography
US9717896B2 (en) 2007-12-18 2017-08-01 Gearbox, Llc Treatment indications informed by a priori implant information
US20090287120A1 (en) 2007-12-18 2009-11-19 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Circulatory monitoring systems and methods
US8636670B2 (en) 2008-05-13 2014-01-28 The Invention Science Fund I, Llc Circulatory monitoring systems and methods
US8388936B2 (en) * 2008-02-22 2013-03-05 Mcw Research Foundation, Inc. In vivo mitochondrial labeling using positively-charged nitroxide enhanced and gadolinium chelate enhanced magnetic resonance imaging
AU2009220244B2 (en) 2008-02-29 2014-10-09 Lantheus Medical Imaging, Inc. Contrast agents for applications including perfusion imaging
US8388931B2 (en) * 2008-02-29 2013-03-05 Marcos Lopez 99m Tc-labeled triphenylphosphonium derivative contrasting agents and molecular probes for early detection and imaging of breast tumors
CA2978149C (en) 2008-03-21 2019-02-12 The General Hospital Corporation Inositol derivatives for the detection and treatment of alzheimer's disease and related disorders
CA2722183C (en) 2008-04-25 2018-09-18 Northwestern University Nanostructures suitable for sequestering cholesterol and other molecules
JP5322527B2 (ja) * 2008-07-17 2013-10-23 浜松ホトニクス株式会社 アポトーシスの検出に適した化合物
KR101602992B1 (ko) 2009-04-15 2016-03-11 랜티우스 메디컬 이메징, 인크. 아스코르브산을 사용한 방사성 약제 조성물의 안정화
CA2767475A1 (en) 2009-07-10 2011-01-13 Bayer Pharma Aktiengesellschaft Usage of low to medium-pressure liquid chromatography for the purification of radiotracers
CN102858752B (zh) 2010-02-08 2018-10-16 兰休斯医疗成像公司 用于合成显像剂和其中间体的方法和装置
GB201005624D0 (en) * 2010-04-01 2010-05-19 Medical Res Council Probe
KR101172157B1 (ko) 2010-05-27 2012-08-07 전남대학교산학협력단 미토콘드리아 영상을 위한 방사성 약물의 제조 방법
US9205156B2 (en) 2010-05-27 2015-12-08 Hadasit Medical Research Services & Development Limited Molecular imaging agents
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CN102898470B (zh) * 2012-11-02 2014-12-10 北京师范大学 一类新型有机膦化合物及其制备方法和应用
JP6527516B2 (ja) 2013-12-03 2019-06-05 ノースウェスタン ユニバーシティ リポソーム粒子、前述のものを作製する方法及びその使用
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WO2016072104A1 (ja) * 2014-11-05 2016-05-12 国立大学法人東北大学 ホスホニウム化合物およびその製造方法
TWI611795B (zh) * 2016-07-18 2018-01-21 許百靈 多針孔單光子ｓｐｅｃｔ心肌血流絕對定量方法與用途
CN107233585B (zh) * 2017-06-09 2021-01-22 四川大学华西医院 黄连素或其衍生物在制备心肌灌注显像剂中的用途
JP2020526558A (ja) 2017-07-13 2020-08-31 ノースウェスタン ユニバーシティ オリゴヌクレオチド官能化金属有機構造体ナノ粒子を調製するための一般的かつ直接的な方法
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CN110577478A (zh) * 2018-10-25 2019-12-17 南方医科大学南方医院 一种正电子探针及其制备方法与应用
US20220347323A1 (en) * 2019-09-18 2022-11-03 The Regents Of The University Of California Positron Emission Tomography Guided Delivery of Mitochondral Complex I Inhibitors
US12319711B2 (en) 2019-09-20 2025-06-03 Northwestern University Spherical nucleic acids with tailored and active protein coronae
US12378560B2 (en) 2019-10-29 2025-08-05 Northwestern University Sequence multiplicity within spherical nucleic acids

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US6630125B2 (en) * 2000-04-28 2003-10-07 Duke University 18F-labeled choline analogs
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EP1474177A4 (en) * 2002-02-06 2010-07-21 Univ Johns Hopkins NONINVASIVE DIAGNOSTIC IMAGING TECHNOLOGY FOR MITOCHONDRIA USING LIPOPHILER SALTS
JP2006512109A (ja) * 2002-08-01 2006-04-13 ザ ジョンズ ホプキンズ ユニバーシティ 蛍光発光を用いた、分子構造の特定技術、および身体内腔の内側に並ぶ細胞種の治療技術

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