JP2005532064A - 改変したｎｓ３ドメインを有するｈｃｖ融合タンパク質 - Google Patents
改変したｎｓ３ドメインを有するｈｃｖ融合タンパク質 Download PDFInfo
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- A61P31/12—Antivirals
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
- C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
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- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Peptides Or Proteins (AREA)
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| EP (1) | EP1539809A4 (enExample) |
| JP (2) | JP2005532064A (enExample) |
| CN (1) | CN1678630A (enExample) |
| AU (1) | AU2003248818A1 (enExample) |
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| PL (1) | PL374349A1 (enExample) |
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| WO (1) | WO2004005473A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2007537757A (ja) * | 2004-05-17 | 2007-12-27 | カイロン コーポレーション | 切断ｃ型肝炎ｎｓ５ドメインおよびこれを含む融合タンパク質 |
| JP2010501580A (ja) * | 2006-08-25 | 2010-01-21 | ノバルティス アーゲー | Ｈｃｖ融合ポリペプチド |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US7491808B2 (en) * | 2000-06-15 | 2009-02-17 | Novartis Vaccines And Diagnostics, Inc. | HCV non-structural protein mutants and uses thereof |
| WO2004039950A2 (en) * | 2002-10-25 | 2004-05-13 | Chiron Corporation | Activation of hcv-specific cells |
| US7439042B2 (en) | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| ES2377978T3 (es) * | 2004-08-27 | 2012-04-03 | Novartis Vaccines And Diagnostics, Inc. | Mutantes de proteínas no estructurales de VHC y usos de los mismos |
| AU2011254055B2 (en) * | 2004-10-18 | 2012-12-20 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| AU2005295317B2 (en) * | 2004-10-18 | 2011-10-13 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| EP1888751A2 (en) * | 2005-05-25 | 2008-02-20 | Tripep Ab | A hepatitis c virus non-structural ns3/4a fusion gene |
| WO2007041861A1 (en) * | 2005-10-13 | 2007-04-19 | Virexx Medical Corp. | Chimeric antigen containing hepatitis c virus polypeptide and fc fragment for eliciting an immune response |
| GB0524408D0 (en) * | 2005-11-30 | 2006-01-11 | Glaxosmithkline Biolog Sa | Vaccines |
| CA2646539A1 (en) | 2006-03-23 | 2007-09-27 | Novartis Ag | Imidazoquinoxaline compounds as immunomodulators |
| US8728489B2 (en) | 2008-09-19 | 2014-05-20 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis C virus infection |
| US9321847B2 (en) | 2010-09-20 | 2016-04-26 | Ramot At Tel Aviv University Ltd. | Activatable toxin complexes comprising a cleavable inhibitory peptide |
| CN107735499B (zh) * | 2015-03-27 | 2022-05-03 | 奥索临床诊断有限公司 | Hcv ns4a/经修饰的ns3多肽及其用途 |
| CN106749672B (zh) * | 2016-11-18 | 2020-06-30 | 江西农业大学 | 一种丙型肝炎病毒融合抗原蛋白及其应用 |
| CN111153963B (zh) * | 2020-01-19 | 2021-08-10 | 华南理工大学 | 抗炎五肽及其提取分离方法和在改善记忆中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2239819T3 (es) * | 1993-11-04 | 2005-10-01 | Innogenetics N.V. | Epitopos inmunodominantes de celulas t humanas del virus de la hepatitis c. |
| EP1233982B1 (en) * | 1999-11-24 | 2007-10-24 | Novartis Vaccines and Diagnostics, Inc. | Novel hcv non-structural polypeptide |
| WO2001090812A1 (en) * | 2000-05-23 | 2001-11-29 | Massachusetts Institute Of Technology | Ultraviolet fluoride nonlinear devices |
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2003
- 2003-07-02 CA CA002491508A patent/CA2491508A1/en not_active Abandoned
- 2003-07-02 EP EP03763172A patent/EP1539809A4/en not_active Withdrawn
- 2003-07-02 WO PCT/US2003/020996 patent/WO2004005473A2/en not_active Ceased
- 2003-07-02 RU RU2005102484/13A patent/RU2005102484A/ru not_active Application Discontinuation
- 2003-07-02 AU AU2003248818A patent/AU2003248818A1/en not_active Abandoned
- 2003-07-02 JP JP2004519849A patent/JP2005532064A/ja active Pending
- 2003-07-02 CN CNA038207192A patent/CN1678630A/zh active Pending
- 2003-07-02 PL PL03374349A patent/PL374349A1/xx not_active Application Discontinuation
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2006
- 2006-06-23 JP JP2006174595A patent/JP2006265267A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007537757A (ja) * | 2004-05-17 | 2007-12-27 | カイロン コーポレーション | 切断ｃ型肝炎ｎｓ５ドメインおよびこれを含む融合タンパク質 |
| JP2010501580A (ja) * | 2006-08-25 | 2010-01-21 | ノバルティス アーゲー | Ｈｃｖ融合ポリペプチド |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2491508A1 (en) | 2004-01-15 |
| JP2006265267A (ja) | 2006-10-05 |
| WO2004005473A2 (en) | 2004-01-15 |
| PL374349A1 (en) | 2005-10-17 |
| WO2004005473A3 (en) | 2004-04-01 |
| CN1678630A (zh) | 2005-10-05 |
| RU2005102484A (ru) | 2006-01-20 |
| AU2003248818A1 (en) | 2004-01-23 |
| EP1539809A2 (en) | 2005-06-15 |
| EP1539809A4 (en) | 2006-03-08 |
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