JP2005531391A - 薬剤放出ステント - Google Patents

薬剤放出ステント Download PDF

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Publication number
JP2005531391A
JP2005531391A JP2004548875A JP2004548875A JP2005531391A JP 2005531391 A JP2005531391 A JP 2005531391A JP 2004548875 A JP2004548875 A JP 2004548875A JP 2004548875 A JP2004548875 A JP 2004548875A JP 2005531391 A JP2005531391 A JP 2005531391A
Authority
JP
Japan
Prior art keywords
drug
eluting stent
stent according
layer
stent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004548875A
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English (en)
Japanese (ja)
Other versions
JP2005531391A5 (enExample
Inventor
一 張
建科 王
智榮 唐
水英 何
順華 周
潤霖 高
俊菲 李
鷹 張
七一 羅
Original Assignee
微創医療器械(上海)有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN 02146905 external-priority patent/CN100471469C/zh
Priority claimed from CNB021551383A external-priority patent/CN1306917C/zh
Priority claimed from CNB031155960A external-priority patent/CN100435880C/zh
Priority claimed from CNA031160638A external-priority patent/CN1533813A/zh
Priority claimed from CNB031289061A external-priority patent/CN100346850C/zh
Application filed by 微創医療器械(上海)有限公司 filed Critical 微創医療器械(上海)有限公司
Publication of JP2005531391A publication Critical patent/JP2005531391A/ja
Publication of JP2005531391A5 publication Critical patent/JP2005531391A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/048Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • A61F2002/075Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • A61L2300/608Coatings having two or more layers
    • A61L2300/61Coatings having two or more layers containing two or more active agents in different layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
JP2004548875A 2002-06-27 2003-06-25 薬剤放出ステント Pending JP2005531391A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CN02112242 2002-06-27
CN 02146905 CN100471469C (zh) 2002-06-27 2002-10-24 一种具有多层涂层的药物洗脱支架
CNB021551383A CN1306917C (zh) 2002-12-17 2002-12-17 一种通过复合作用机理预防/治疗血管内再狭窄的支架
CNB031155960A CN100435880C (zh) 2003-02-28 2003-02-28 一种药物洗脱介入医疗器械及其制备方法
CNA031160638A CN1533813A (zh) 2003-03-28 2003-03-28 预防/治疗皮腔内冠状动脉成形术后再狭窄的药物涂层支架
CNB031289061A CN100346850C (zh) 2003-05-28 2003-05-28 一种药物涂层支架
PCT/CN2003/000489 WO2004002367A1 (en) 2002-06-27 2003-06-25 Drug eluting stent

Publications (2)

Publication Number Publication Date
JP2005531391A true JP2005531391A (ja) 2005-10-20
JP2005531391A5 JP2005531391A5 (enExample) 2006-08-10

Family

ID=30004063

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004548875A Pending JP2005531391A (ja) 2002-06-27 2003-06-25 薬剤放出ステント

Country Status (5)

Country Link
US (2) US20050033414A1 (enExample)
EP (1) EP1516597A4 (enExample)
JP (1) JP2005531391A (enExample)
AU (1) AU2003280437A1 (enExample)
WO (1) WO2004002367A1 (enExample)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007117742A (ja) * 2005-10-27 2007-05-17 Cordis Corp 脈管の病気の治療のためのラパマイシンおよびシロスタゾールの組み合わせ物の局所的投与
JP2010522175A (ja) * 2007-03-20 2010-07-01 ボストン サイエンティフィック サイムド,インコーポレイテッド 治療薬を放出するための泌尿器科学的医療機器
WO2011024831A1 (ja) 2009-08-26 2011-03-03 国立大学法人九州大学 管腔内留置用医療デバイス及びその製造方法
JP2015078198A (ja) * 2006-09-26 2015-04-23 ノバルティス アーゲー S1p調節剤を含む医薬組成物
WO2019182003A1 (ja) * 2018-03-22 2019-09-26 株式会社日本医療機器技研 生体吸収性ステント
JPWO2021006291A1 (enExample) * 2019-07-09 2021-01-14
US11241322B2 (en) 2014-10-28 2022-02-08 Jimro Co., Ltd. Drug-eluting stent
US11248282B2 (en) 2017-01-10 2022-02-15 Fuji Light Metal Co., Ltd. Magnesium alloy
US11685975B2 (en) 2018-07-09 2023-06-27 Japan Medical Device Technology Co., Ltd. Magnesium alloy

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2178541C (en) * 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
EP1516597A4 (en) * 2002-06-27 2010-11-10 Microport Medical Shanghai Co MEDICINES ELUTIONSSTENT
US7727153B2 (en) * 2003-04-07 2010-06-01 Sonosite, Inc. Ultrasonic blood vessel measurement apparatus and method
US8003122B2 (en) * 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
ES2663495T3 (es) * 2005-02-18 2018-04-13 Abraxis Bioscience, Llc Fármacos con hidrofobicidad mejorada para incorporación en dispositivos médicos
ES2691646T3 (es) 2005-07-15 2018-11-28 Micell Technologies, Inc. Revestimientos poliméricos que contienen polvo de fármaco de morfología controlada
US20090062909A1 (en) 2005-07-15 2009-03-05 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
US20070031611A1 (en) * 2005-08-04 2007-02-08 Babaev Eilaz P Ultrasound medical stent coating method and device
US9101949B2 (en) * 2005-08-04 2015-08-11 Eilaz Babaev Ultrasonic atomization and/or seperation system
US7896539B2 (en) * 2005-08-16 2011-03-01 Bacoustics, Llc Ultrasound apparatus and methods for mixing liquids and coating stents
US8852625B2 (en) 2006-04-26 2014-10-07 Micell Technologies, Inc. Coatings containing multiple drugs
US20070254003A1 (en) * 2006-05-01 2007-11-01 Pu Zhou Non-sticky coatings with therapeutic agents for medical devices
US20070259101A1 (en) * 2006-05-02 2007-11-08 Kleiner Lothar W Microporous coating on medical devices
US7731987B2 (en) * 2006-07-13 2010-06-08 Advanced Cardiovascular Systems, Inc. Implantable medical device comprising a pro-healing poly(ester-amide)
US20090181063A1 (en) * 2006-07-13 2009-07-16 Michael Huy Ngo Implantable medical device comprising a pro-healing poly(ester-amide)
US20080142616A1 (en) * 2006-12-15 2008-06-19 Bacoustics Llc Method of Producing a Directed Spray
US8147539B2 (en) * 2006-12-20 2012-04-03 Boston Scientific Scimed, Inc. Stent with a coating for delivering a therapeutic agent
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
CN101711137B (zh) 2007-01-08 2014-10-22 米歇尔技术公司 具有可生物降解层的支架
US8221496B2 (en) * 2007-02-01 2012-07-17 Cordis Corporation Antithrombotic and anti-restenotic drug eluting stent
US7753285B2 (en) 2007-07-13 2010-07-13 Bacoustics, Llc Echoing ultrasound atomization and/or mixing system
US7780095B2 (en) 2007-07-13 2010-08-24 Bacoustics, Llc Ultrasound pumping apparatus
US20090186068A1 (en) * 2008-01-18 2009-07-23 Chameleon Scientific Corporation Atomic plasma deposited coatings for drug release
EA020655B1 (ru) 2008-04-17 2014-12-30 Миселл Текнолоджиз, Инк. Стенты, имеющие биорассасывающиеся слои
CA2730995C (en) 2008-07-17 2016-11-22 Micell Technologies, Inc. Drug delivery medical device
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
US8642063B2 (en) * 2008-08-22 2014-02-04 Cook Medical Technologies Llc Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
CN102481195B (zh) 2009-04-01 2015-03-25 米歇尔技术公司 涂覆支架
EP3366326A1 (en) 2009-04-17 2018-08-29 Micell Technologies, Inc. Stents having controlled elution
US8709467B2 (en) 2009-06-26 2014-04-29 Cute Lovable Teddy Bear, Llc. Para-xylylene based microfilm elution devices
EP2531140B1 (en) 2010-02-02 2017-11-01 Micell Technologies, Inc. Stent and stent delivery system with improved deliverability
EP2560576B1 (en) 2010-04-22 2018-07-18 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
CA2805631C (en) 2010-07-16 2018-07-31 Micell Technologies, Inc. Drug delivery medical device
WO2013012689A1 (en) 2011-07-15 2013-01-24 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
US20130183435A1 (en) * 2012-01-13 2013-07-18 Hongmin Sun Low temperature plasma coating for anti-biofilm formation
US9718781B2 (en) 2012-04-17 2017-08-01 University College Dublin, National University Of Ireland, Dublin Methods and compounds for treating proliferative disorders and viral infections
EP2838520B1 (en) 2012-04-17 2017-12-13 University College Dublin National University Of Ireland, Dublin Thromboxane receptor antagonists
US11039943B2 (en) 2013-03-12 2021-06-22 Micell Technologies, Inc. Bioabsorbable biomedical implants
CA2912387C (en) 2013-05-15 2019-04-16 Micell Technologies, Inc. Bioabsorbable biomedical implants
TWI697337B (zh) 2013-08-07 2020-07-01 學校法人近畿大學 奈米粒子或奈米粒子組成物之製造方法,及支架或球囊導管之製造方法
ES2858551T3 (es) 2015-06-16 2021-09-30 Atxa Therapeutics Ltd Antagonistas del receptor de tromboxano
WO2022065942A1 (ko) * 2020-09-25 2022-03-31 가톨릭대학교 산학협력단 의료기기 코팅용 조성물

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS585196A (ja) * 1981-06-30 1983-01-12 Kyowa Hakko Kogyo Co Ltd 抗腫瘍性物質の製造法
WO2000032255A1 (en) * 1998-12-03 2000-06-08 Boston Scientific Limited Polymeric coatings with controlled delivery of active agents
WO2000045744A1 (en) * 1999-02-03 2000-08-10 Boston Scientific Limited Surface protection method for stents and balloon catheters for drug delivery
WO2001045763A1 (en) * 1999-12-23 2001-06-28 Advanced Cardiovascular Systems, Inc. Biocomptabible coating
JP2001190687A (ja) * 2000-01-07 2001-07-17 Kawasumi Lab Inc ステント及びステントグラフト
WO2002026281A1 (en) * 2000-09-29 2002-04-04 Cordis Corporation Coated medical devices
WO2002040000A2 (en) * 2000-11-15 2002-05-23 Wyeth Use of cci-779 as an antineoplastic agent
JP2003175058A (ja) * 2001-10-02 2003-06-24 Cordis Corp 冠状動脈の閉塞を治療するための手段および方法
JP2005508671A (ja) * 2001-07-26 2005-04-07 アバンテク バスキュラー コーポレーション 治療に有効な薬剤の送達

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991052A (en) * 1975-07-18 1976-11-09 Eli Lilly And Company Antibiotic A-30641
JPS5862152A (ja) * 1981-10-08 1983-04-13 Microbial Chem Res Found N−〔4−(3−アミノプロピル)アミノブチル〕−2−(ω−グアニジノ脂肪酸アミド)−2−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法
US4981792A (en) * 1988-06-29 1991-01-01 Merck & Co., Inc. Immunosuppressant compound
US5091205A (en) * 1989-01-17 1992-02-25 Union Carbide Chemicals & Plastics Technology Corporation Hydrophilic lubricious coatings
CN1037526C (zh) * 1991-03-01 1998-02-25 中国医学科学院医药生物技术研究所 康乐霉素c的生产方法
US5599352A (en) * 1992-03-19 1997-02-04 Medtronic, Inc. Method of making a drug eluting stent
US5283257A (en) * 1992-07-10 1994-02-01 The Board Of Trustees Of The Leland Stanford Junior University Method of treating hyperproliferative vascular disease
JP2617407B2 (ja) * 1992-09-14 1997-06-04 キッセイ薬品工業株式会社 血管内膜細胞過剰増殖疾患の予防および治療剤
US5464650A (en) * 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
EG20321A (en) * 1993-07-21 1998-10-31 Otsuka Pharma Co Ltd Medical material and process for producing the same
US6231600B1 (en) * 1995-02-22 2001-05-15 Scimed Life Systems, Inc. Stents with hybrid coating for medical devices
US5723219A (en) * 1995-12-19 1998-03-03 Talison Research Plasma deposited film networks
AU737078C (en) * 1996-05-24 2002-05-02 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating or preventing diseases of body passageways
US20020042645A1 (en) * 1996-07-03 2002-04-11 Shannon Donald T. Drug eluting radially expandable tubular stented grafts
US20030083461A1 (en) * 1997-06-16 2003-05-01 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6890546B2 (en) * 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US6024918A (en) * 1998-03-13 2000-02-15 Medtronic, Inc. Method for attachment of biomolecules to surfaces of medical devices
US6407244B1 (en) * 2000-01-26 2002-06-18 Gemin X Biotechnologies Inc. Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases
KR100860860B1 (ko) * 2000-03-15 2008-09-29 오르버스네이치 메디칼 인코포레이티드 내피 세포 부착을 촉진하는 코팅
US7470228B2 (en) * 2000-04-14 2008-12-30 Attenuex Technologies, Inc. Method of treating benign hypertrophy of the prostate
US6489314B1 (en) * 2001-04-03 2002-12-03 Kosan Biosciences, Inc. Epothilone derivatives and methods for making and using the same
AU2001266583A1 (en) * 2000-05-26 2001-12-11 Kosan Biosciences, Inc. Epothilone derivatives and methods for making and using the same
US20020051730A1 (en) * 2000-09-29 2002-05-02 Stanko Bodnar Coated medical devices and sterilization thereof
AU9486901A (en) * 2000-09-29 2002-04-08 Cordis Corp Coated medical devices
US20020111590A1 (en) * 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
US6534693B2 (en) * 2000-11-06 2003-03-18 Afmedica, Inc. Surgically implanted devices having reduced scar tissue formation
US7083642B2 (en) * 2000-12-22 2006-08-01 Avantec Vascular Corporation Delivery of therapeutic capable agents
US7077859B2 (en) * 2000-12-22 2006-07-18 Avantec Vascular Corporation Apparatus and methods for variably controlled substance delivery from implanted prostheses
US20020082679A1 (en) * 2000-12-22 2002-06-27 Avantec Vascular Corporation Delivery or therapeutic capable agents
CN1360951A (zh) * 2000-12-28 2002-07-31 微创医疗器械(上海)有限公司 一种具有防再狭窄涂层的血管支架
US20020120333A1 (en) * 2001-01-31 2002-08-29 Keogh James R. Method for coating medical device surfaces
US6893859B2 (en) * 2001-02-13 2005-05-17 Kosan Biosciences, Inc. Epothilone derivatives and methods for making and using the same
JP2005523416A (ja) * 2001-03-20 2005-08-04 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 哺乳動物組織の中のセリンパルミトイルトランスフェラーゼを測定する方法およびそれの使用
US20020146385A1 (en) * 2001-04-10 2002-10-10 Lin Tung Liang Ionic antimicrobial coating
US7195640B2 (en) * 2001-09-25 2007-03-27 Cordis Corporation Coated medical devices for the treatment of vulnerable plaque
US20030065345A1 (en) * 2001-09-28 2003-04-03 Kevin Weadock Anastomosis devices and methods for treating anastomotic sites
US7108701B2 (en) * 2001-09-28 2006-09-19 Ethicon, Inc. Drug releasing anastomosis devices and methods for treating anastomotic sites
US6939376B2 (en) * 2001-11-05 2005-09-06 Sun Biomedical, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US20030088307A1 (en) * 2001-11-05 2003-05-08 Shulze John E. Potent coatings for stents
AU2002360430A1 (en) * 2001-11-26 2003-06-10 Kosan Biosciences, Inc. 14-methyl-epothilones
CN1303947C (zh) * 2001-12-13 2007-03-14 华东理工大学 药物洗脱性心血管支架及其制备方法
EP1516597A4 (en) * 2002-06-27 2010-11-10 Microport Medical Shanghai Co MEDICINES ELUTIONSSTENT

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS585196A (ja) * 1981-06-30 1983-01-12 Kyowa Hakko Kogyo Co Ltd 抗腫瘍性物質の製造法
WO2000032255A1 (en) * 1998-12-03 2000-06-08 Boston Scientific Limited Polymeric coatings with controlled delivery of active agents
WO2000045744A1 (en) * 1999-02-03 2000-08-10 Boston Scientific Limited Surface protection method for stents and balloon catheters for drug delivery
WO2001045763A1 (en) * 1999-12-23 2001-06-28 Advanced Cardiovascular Systems, Inc. Biocomptabible coating
JP2001190687A (ja) * 2000-01-07 2001-07-17 Kawasumi Lab Inc ステント及びステントグラフト
WO2002026281A1 (en) * 2000-09-29 2002-04-04 Cordis Corporation Coated medical devices
WO2002040000A2 (en) * 2000-11-15 2002-05-23 Wyeth Use of cci-779 as an antineoplastic agent
JP2005508671A (ja) * 2001-07-26 2005-04-07 アバンテク バスキュラー コーポレーション 治療に有効な薬剤の送達
JP2003175058A (ja) * 2001-10-02 2003-06-24 Cordis Corp 冠状動脈の閉塞を治療するための手段および方法

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007117742A (ja) * 2005-10-27 2007-05-17 Cordis Corp 脈管の病気の治療のためのラパマイシンおよびシロスタゾールの組み合わせ物の局所的投与
JP2015078198A (ja) * 2006-09-26 2015-04-23 ノバルティス アーゲー S1p調節剤を含む医薬組成物
JP2010522175A (ja) * 2007-03-20 2010-07-01 ボストン サイエンティフィック サイムド,インコーポレイテッド 治療薬を放出するための泌尿器科学的医療機器
WO2011024831A1 (ja) 2009-08-26 2011-03-03 国立大学法人九州大学 管腔内留置用医療デバイス及びその製造方法
US11241322B2 (en) 2014-10-28 2022-02-08 Jimro Co., Ltd. Drug-eluting stent
US11248282B2 (en) 2017-01-10 2022-02-15 Fuji Light Metal Co., Ltd. Magnesium alloy
WO2019182003A1 (ja) * 2018-03-22 2019-09-26 株式会社日本医療機器技研 生体吸収性ステント
US12109333B2 (en) 2018-03-22 2024-10-08 Japan Medical Device Technology Co., Ltd. Bioabsorbable stent
US11685975B2 (en) 2018-07-09 2023-06-27 Japan Medical Device Technology Co., Ltd. Magnesium alloy
WO2021006291A1 (ja) * 2019-07-09 2021-01-14 大塚メディカルデバイス株式会社 薬剤溶出型ステント
JPWO2021006291A1 (enExample) * 2019-07-09 2021-01-14
JP7033694B2 (ja) 2019-07-09 2022-03-10 大塚メディカルデバイス株式会社 薬剤溶出型ステント
JP2022078154A (ja) * 2019-07-09 2022-05-24 大塚メディカルデバイス株式会社 薬剤溶出型ステント
US20220160525A1 (en) * 2019-07-09 2022-05-26 Otsuka Medical Devices Co., Ltd Drug-eluting stent
JP7200412B2 (ja) 2019-07-09 2023-01-06 大塚メディカルデバイス株式会社 薬剤溶出型ステント
US11806257B2 (en) * 2019-07-09 2023-11-07 Otsuka Medical Devices Co., Ltd. Drug-eluting stent including crystalline cilostazol
US12485026B2 (en) * 2019-07-09 2025-12-02 Otsuka Medical Devices Co., Ltd. Drug-eluting stent including crystalline cilostazol

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