JP2005529904A5 - - Google Patents
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- Publication number
- JP2005529904A5 JP2005529904A5 JP2004500865A JP2004500865A JP2005529904A5 JP 2005529904 A5 JP2005529904 A5 JP 2005529904A5 JP 2004500865 A JP2004500865 A JP 2004500865A JP 2004500865 A JP2004500865 A JP 2004500865A JP 2005529904 A5 JP2005529904 A5 JP 2005529904A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- ethylphenyl
- triazole
- methoxyphenyl
- uveitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- NAUNDFHXCIMBKS-UHFFFAOYSA-N 1-[3-(2-ethylphenyl)-5-methoxyphenyl]-1,2,4-triazole Chemical compound CCC1=CC=CC=C1C1=CC(OC)=CC(N2N=CN=C2)=C1 NAUNDFHXCIMBKS-UHFFFAOYSA-N 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 206010003816 Autoimmune disease Diseases 0.000 claims 1
- 206010039073 Rheumatoid arthritis Diseases 0.000 claims 1
- 210000001744 T-Lymphocytes Anatomy 0.000 claims 1
- 206010046851 Uveitis Diseases 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
Claims (4)
- （３−（２−エチルフェニル）−５−メトキシフェニル）−１Ｈ−［１，２，４］−トリアゾールを含む、多発性硬化症、全身性エリテマトーデス、関節リウマチおよびブドウ膜炎からなる群から選択される自己免疫疾患の治療のための医薬組成物。
- （３−（２−エチルフェニル）−５−メトキシフェニル）−１Ｈ−［１，２，４］−トリアゾールを含む、γδＴ細胞の阻害のための医薬組成物。
- 哺乳類のためのものである、請求項１または２のいずれかの医薬組成物。
- 該哺乳類がヒトである請求項３の医薬組成物。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/137,699 US6797722B2 (en) | 2002-05-03 | 2002-05-03 | Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases |
| PCT/IT2003/000237 WO2003092681A1 (en) | 2002-05-03 | 2003-04-15 | Use of (3-(2-ethylphenyl)-5-methoxyphenyl)-1h-[1,2,4]-triazole for the treatment of autoimmune diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005529904A JP2005529904A (ja) | 2005-10-06 |
| JP2005529904A5 true JP2005529904A5 (ja) | 2006-06-08 |
Family
ID=29269138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004500865A Pending JP2005529904A (ja) | 2002-05-03 | 2003-04-15 | 自己免疫疾患の治療のための（３−（２−エチルフェニル）−５−メトキシフェニル）−１ｈ−［１，２，４］−トリアゾールの使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6797722B2 (ja) |
| EP (1) | EP1501505B1 (ja) |
| JP (1) | JP2005529904A (ja) |
| KR (1) | KR20040111491A (ja) |
| AT (1) | ATE315935T1 (ja) |
| AU (1) | AU2003224453A1 (ja) |
| CA (1) | CA2483904A1 (ja) |
| DE (1) | DE60303296T2 (ja) |
| DK (1) | DK1501505T3 (ja) |
| ES (1) | ES2257666T3 (ja) |
| MX (1) | MXPA04010785A (ja) |
| PL (1) | PL374252A1 (ja) |
| PT (1) | PT1501505E (ja) |
| TW (1) | TWI284532B (ja) |
| WO (1) | WO2003092681A1 (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY142651A (en) * | 2003-03-18 | 2010-12-15 | Merck Sharp & Dohme | Biaryl substituted triazoles as sodium channel blockers |
| EP1720567A2 (en) * | 2004-02-10 | 2006-11-15 | Innate Pharma | Composition and method for the treatment of carcinoma |
| EP1921073A1 (en) | 2006-11-10 | 2008-05-14 | Laboratorios del Dr. Esteve S.A. | 1,2,4-Triazole derivatives as sigma receptor inhibitors |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4379155A (en) * | 1979-06-11 | 1983-04-05 | Gruppo Lepetit S.P.A. | 3,5-Disubstituted-1H-1,2,4-triazole derivatives |
| JPS58126810A (ja) * | 1981-12-24 | 1983-07-28 | Kaken Pharmaceut Co Ltd | 抗炎症眼科用液剤およびその製法 |
| DE3808283A1 (de) * | 1988-03-12 | 1989-09-21 | Boehringer Ingelheim Kg | Neue 3,4,5-substituierte 4h-1,2,4-triazole, ihre herstellung und verwendung |
| US4895872A (en) * | 1989-03-15 | 1990-01-23 | Cetus Corporation | Immunosupressive analogues and derivatives of succinylacetone |
| US5273979A (en) * | 1991-08-01 | 1993-12-28 | Merck & Co., Inc. | C-31 desmethyl FR-900520 cyclic hemiketal immunosuppressant agent |
| US5189042A (en) * | 1991-08-22 | 1993-02-23 | Merck & Co. Inc. | Fluoromacrolides having immunosuppressive activity |
| US5484788A (en) * | 1993-03-26 | 1996-01-16 | Beth Israel Hospital Association | Buspirone as a systemic immunosuppressant |
| DE4320801A1 (de) * | 1993-06-23 | 1995-01-05 | Fahlberg List Pharma Gmbh | 2-Hydroxyphenylsubstituierte 1,2,4-Triazole und 1,2,4-Oxadiazole, ihre Verwendung als pharmazeutische Wirkstoffe und sie enthaltende Arzneimittel |
| WO1997026278A1 (en) * | 1996-01-18 | 1997-07-24 | Steeno Research Group A/S | Synthetic il-10 analogues |
| PT1002792E (pt) * | 1997-04-04 | 2004-12-31 | Mitsubishi Pharma Corp | Compostos de 2-aminopropano-1,3-diol, sua utilizacao medicinal e intermediariosda sintese dos mesmos |
| IT1292092B1 (it) * | 1997-06-05 | 1999-01-25 | Geange Ltd | Impiego di derivati eterociclici aromatici azotati nel trattamento topico di affezioni di tessuti epiteliali |
| EP1099695A1 (en) * | 1999-11-09 | 2001-05-16 | Laboratoire Theramex S.A. | 5-aryl-1H-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them |
-
2002
- 2002-05-03 US US10/137,699 patent/US6797722B2/en not_active Expired - Fee Related
-
2003
- 2003-04-15 EP EP03720879A patent/EP1501505B1/en not_active Expired - Lifetime
- 2003-04-15 JP JP2004500865A patent/JP2005529904A/ja active Pending
- 2003-04-15 PT PT03720879T patent/PT1501505E/pt unknown
- 2003-04-15 PL PL03374252A patent/PL374252A1/xx not_active Application Discontinuation
- 2003-04-15 ES ES03720879T patent/ES2257666T3/es not_active Expired - Lifetime
- 2003-04-15 CA CA002483904A patent/CA2483904A1/en not_active Abandoned
- 2003-04-15 MX MXPA04010785A patent/MXPA04010785A/es active IP Right Grant
- 2003-04-15 KR KR10-2004-7015884A patent/KR20040111491A/ko not_active Application Discontinuation
- 2003-04-15 AT AT03720879T patent/ATE315935T1/de not_active IP Right Cessation
- 2003-04-15 WO PCT/IT2003/000237 patent/WO2003092681A1/en active IP Right Grant
- 2003-04-15 AU AU2003224453A patent/AU2003224453A1/en not_active Abandoned
- 2003-04-15 DE DE60303296T patent/DE60303296T2/de not_active Expired - Fee Related
- 2003-04-15 DK DK03720879T patent/DK1501505T3/da active
- 2003-04-22 TW TW092109389A patent/TWI284532B/zh not_active IP Right Cessation
-
2004
- 2004-03-30 US US10/812,308 patent/US20050026980A1/en not_active Abandoned
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