JP2005528359A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005528359A5 JP2005528359A5 JP2003577780A JP2003577780A JP2005528359A5 JP 2005528359 A5 JP2005528359 A5 JP 2005528359A5 JP 2003577780 A JP2003577780 A JP 2003577780A JP 2003577780 A JP2003577780 A JP 2003577780A JP 2005528359 A5 JP2005528359 A5 JP 2005528359A5
- Authority
- JP
- Japan
- Prior art keywords
- transdermal
- depression
- dosage
- buprenorphine
- transdermal dosage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- RMRJXGBAOAMLHD-CTAPUXPBSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-CTAPUXPBSA-N 0.000 claims 3
- 229960001736 buprenorphine Drugs 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 2
- 239000006211 transdermal dosage form Substances 0.000 claims 2
- 229940100640 Transdermal System Drugs 0.000 claims 1
- 238000009792 diffusion process Methods 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 230000000699 topical Effects 0.000 claims 1
Claims (5)
- うつ病の治療方法であって、うつ病を患っている患者に、ブプレノルフィンを含んでいる経皮投薬形態を投与し、これによって患者におけるうつ病の１つもしくはそれ以上の症状を緩和することを含む方法。
- うつ病を患っている患者への、ブプレノルフィンを含んでいる第一、第二、および第三経皮投薬物の連続投与を含むうつ病の治療方法であって、第三投薬物が、第一および第二投薬物よりも高い投薬量のブプレノルフィンを含み、これによって患者におけるうつ病の１つもしくはそれ以上の症状を緩和する方法。
- この経皮投薬形態が、経皮投薬物および経皮投薬組成物からなる群から選択される、請求項１又は２に記載の方法。
- この経皮投薬物が、拡散駆動経皮系である、請求項３に記載の方法。
- この経皮投薬組成物は、局所ジェル、ローション、軟膏、経粘膜系、経粘膜器具、およびイオン導入送達系からなる群から選択される、請求項３に記載の方法。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36635802P | 2002-03-20 | 2002-03-20 | |
| PCT/US2003/008796 WO2003079945A1 (en) | 2002-03-20 | 2003-03-20 | Method of administering buprenorphine to treat depression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005528359A JP2005528359A (ja) | 2005-09-22 |
| JP2005528359A5 true JP2005528359A5 (ja) | 2006-05-11 |
Family
ID=28454789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003577780A Pending JP2005528359A (ja) | 2002-03-20 | 2003-03-20 | うつ病の治療のためのブプレノルフィンの投与方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20030181475A1 (ja) |
| EP (1) | EP1485051B1 (ja) |
| JP (1) | JP2005528359A (ja) |
| AT (1) | ATE394097T1 (ja) |
| AU (1) | AU2003224742A1 (ja) |
| CY (1) | CY1108217T1 (ja) |
| DE (1) | DE60320770D1 (ja) |
| DK (1) | DK1485051T3 (ja) |
| ES (1) | ES2305457T3 (ja) |
| PT (1) | PT1485051E (ja) |
| SI (1) | SI1485051T1 (ja) |
| WO (1) | WO2003079945A1 (ja) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| EP1913938A1 (en) * | 2002-12-13 | 2008-04-23 | Euro-Celtique S.A. | Transdermal buprenorphine dosage regimen for analgesia |
| ATE400258T1 (de) * | 2002-12-13 | 2008-07-15 | Euro Celtique Sa | Transdermales buprenorphin-dosierschema zwecks schmerzstillung |
| AR047936A1 (es) | 2003-04-30 | 2006-03-15 | Purdue Pharma Ltd | Forma de dosificacion transdermica resistente a la manipulacion |
| US8790689B2 (en) | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| ATE375149T1 (de) | 2003-07-25 | 2007-10-15 | Euro Celtique Sa | Behandlung von entzug |
| DE10340428B4 (de) * | 2003-09-02 | 2015-02-12 | Acino Ag | Opioides Analgetikum enthaltende transdermale Formulierung |
| FR2865650B1 (fr) * | 2004-01-30 | 2008-06-13 | Biocortech | Utilisation du 14,15 dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures et les desordres du cycle veille-sommeil |
| DE102004045599A1 (de) * | 2004-09-17 | 2006-03-23 | Grünenthal GmbH | System zur sequentiellen, transdermalen Verabreichung von systemisch wirksamen Substanzen |
| DE102005007859A1 (de) * | 2005-02-21 | 2006-08-24 | Lts Lohmann Therapie-Systeme Ag | Vefahren für eine medikamentöse Kombinations-Behandlung, sowie hierfür geeignete Arzneimittel-Kombinationen |
| DE102006011340A1 (de) * | 2006-03-09 | 2007-09-20 | Grünenthal GmbH | Wirkstoffhaltige Pflaster mit verbesserter Handhabung |
| RS58894B1 (sr) | 2009-12-04 | 2019-08-30 | Alkermes Pharma Ireland Ltd | Derivati morfinana za lečenje predoziranja lekom |
| HUE041981T2 (hu) | 2010-08-23 | 2019-06-28 | Alkermes Pharma Ireland Ltd | Eljárások antipszichotikum által kiváltott súlygyarapodás kezelésére |
| WO2013042054A1 (en) * | 2011-09-19 | 2013-03-28 | Carmel - Haifa University Economic Corporation Ltd. | Buprenorphine for the treatment of acute suicidality |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| EP2790702B1 (en) * | 2011-12-15 | 2020-04-01 | Alkermes Pharma Ireland Limited | Compositions of buprenorphine and mu-opioid receptor antagonists |
| AU2012351805B2 (en) * | 2011-12-15 | 2016-04-21 | Alkermes Pharma Ireland Limited | Samidorphan (ALKS 33) in combination with opioid agonists |
| US10195191B2 (en) | 2011-12-15 | 2019-02-05 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| WO2014190270A1 (en) | 2013-05-24 | 2014-11-27 | Alkermes Pharma Ireland Limited | Morphan and morphinan analogues, and methods of use |
| US9656961B2 (en) | 2013-05-24 | 2017-05-23 | Alkermes Pharma Ireland Limited | Methods for treating depressive symptoms |
| ES2694352T3 (es) * | 2013-12-20 | 2018-12-20 | H. Lundbeck A/S | Uso de un antagonista del receptor opioide con actividad kappa, y vortioxetina para el tratamiento del trastorno depresivo con características melancólicas |
| WO2022101444A1 (en) | 2020-11-12 | 2022-05-19 | Alkermes Pharma Ireland Limited | Immediate release multilayer tablet |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806341A (en) * | 1985-02-25 | 1989-02-21 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration |
| US5026556A (en) * | 1988-11-10 | 1991-06-25 | Norwich Eaton Pharmaceuticals, Inc. | Compositions for the transdermal delivery of pharmaceutical actives |
| US4956171A (en) * | 1989-07-21 | 1990-09-11 | Paco Pharmaceutical Services, Inc. | Transdermal drug delivery using a dual permeation enhancer and method of performing the same |
| US5240711A (en) * | 1989-11-29 | 1993-08-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system comprising as active component buprenorphine |
| DE69115445T2 (de) * | 1990-04-24 | 1996-06-20 | Teijin Ltd | Pflaster |
| US5069909A (en) * | 1990-06-20 | 1991-12-03 | Cygnus Therapeutic Systems | Transdermal administration of buprenorphine |
| US5512593A (en) * | 1993-03-02 | 1996-04-30 | John S. Nagle | Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhibitor |
| US5613958A (en) * | 1993-05-12 | 1997-03-25 | Pp Holdings Inc. | Transdermal delivery systems for the modulated administration of drugs |
| US6165499A (en) * | 1996-03-25 | 2000-12-26 | Lts Lohmann Therapie-Systeme Gmbh | Transdermal therapeutic system with small application-area thickness and great flexibility, and production process |
| US6787149B1 (en) * | 1996-12-12 | 2004-09-07 | El Khoury And Stein Ltd. | Topical application of opioid analgesic drugs such as morphine |
| US5968547A (en) * | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US5900420A (en) * | 1997-06-19 | 1999-05-04 | Cole; William L. | Method for treating chronic fatigue syndrome and fibromyalgia with buprenorphine |
| DE19738855C2 (de) * | 1997-09-05 | 2001-01-04 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit haftklebender Reservoirschicht und unidirektional elastischer Rückschicht |
| DE19746191C2 (de) * | 1997-10-18 | 2000-05-18 | Lohmann Therapie Syst Lts | Verfahren zur Anwendung eines Wirkstoff enthaltenden Pflasters zur Bekämpfung oder Linderung einer Sucht |
| US6242456B1 (en) * | 1998-03-09 | 2001-06-05 | Trustees Of Tufts College | Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors |
| DE19840758A1 (de) * | 1998-09-07 | 2000-03-09 | Liedtke Pharmed Gmbh | Systemische Therapie von Schmerz- und depressiver Befindlichkeit |
-
2003
- 2003-03-20 JP JP2003577780A patent/JP2005528359A/ja active Pending
- 2003-03-20 WO PCT/US2003/008796 patent/WO2003079945A1/en active Application Filing
- 2003-03-20 DK DK03721427T patent/DK1485051T3/da active
- 2003-03-20 ES ES03721427T patent/ES2305457T3/es not_active Expired - Lifetime
- 2003-03-20 PT PT03721427T patent/PT1485051E/pt unknown
- 2003-03-20 AU AU2003224742A patent/AU2003224742A1/en not_active Abandoned
- 2003-03-20 SI SI200331272T patent/SI1485051T1/sl unknown
- 2003-03-20 AT AT03721427T patent/ATE394097T1/de active
- 2003-03-20 EP EP03721427A patent/EP1485051B1/en not_active Expired - Lifetime
- 2003-03-20 DE DE60320770T patent/DE60320770D1/de not_active Expired - Lifetime
- 2003-03-20 US US10/394,425 patent/US20030181475A1/en not_active Abandoned
-
2008
- 2008-07-28 CY CY20081100780T patent/CY1108217T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005528359A5 (ja) | ||
| NO20060913L (no) | Behandling av avhengighetsabstinens | |
| DE69826644D1 (de) | Topische pharmazeutische zusammensetzung, enthaltend einen cholinergischen wirkstoff oder einen kalziumkanalblocker | |
| JP2011252020A5 (ja) | ||
| WO2001082914A3 (en) | Topical anesthetic/opioid formulations and uses thereof | |
| NO20001175L (no) | Smertestillende blandinger omfattende anti-epileptiske forbindelser og fremgangsmõter for anvendelse derav | |
| JP2009544619A5 (ja) | ||
| UA88464C2 (ru) | Способ дермального введения метадоновой композиции с обеспечением системного действия | |
| DE60034667D1 (de) | Pharmazeutische zusammensetzung aus komplexen kohlenhydraten deren anwendung | |
| WO2004080413A3 (en) | Uses and formulations for transdermal or transmucosal application of active agents | |
| CY1108217T1 (el) | Μεθοδος χορηγησης βουπρενορφινης για τη θεραπεια της καταθλιψης | |
| JP2007500134A5 (ja) | ||
| JP2006513184A5 (ja) | ||
| DK1572167T3 (da) | Transdermal buprenophindoseringsbehandlingsplan for analgesi | |
| PT1274429E (pt) | Formulações tópicas para administração transdérmica de prófármacos de niacina e métodos para tratar a hiperlipidemia | |
| IL167890A (en) | Use of a chorionic gonadotropin in the preparation of a medicament for treating a chronic pelvic pain syndrome | |
| BRPI0514600A (pt) | métodos para a fabricação de um composto, para a purificação de um composto, para o tratamento de um indivìduo tendo uma condição neoplástica, tendo carcinoma de célula escamosa, e tendo carcinoma de célula basal, para a redução ou prevenção da ocorrência de uma condição neoplástica em um indivìduo, e para a redução de triglicerìdeos no soro em um indivìduo, composto, e, composição farmacêutica | |
| CA2529983A1 (en) | Preoperative treatment of post operative pain | |
| RU2002103808A (ru) | Способ лечения болевого синдрома у онкологических больных | |
| WO2006117404A3 (de) | Topische verwendung von radikalfangenden substanzen zur antipyretischen behandlung | |
| WO2003068156A3 (en) | Methods for treating or inhibiting sick building syndrome, post-lyme disease syndrome, and/or chronic fatigue syndrome | |
| BR0313305A (pt) | Agente analgésico para indivìduos recém-nascidos ou fetais | |
| Giusti et al. | Alternative Routes for Systemic Opioid Delivery | |
| WO2003059284A3 (en) | Composition and method for inhibiting hypersensitivity | |
| DE60012575D1 (de) | Nsaid enthaltendes wasserfreies gel zur topischen anwendung in der mundhöhle |