JP2005528175A - 血流同期mri - Google Patents
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- JP2005528175A JP2005528175A JP2004509446A JP2004509446A JP2005528175A JP 2005528175 A JP2005528175 A JP 2005528175A JP 2004509446 A JP2004509446 A JP 2004509446A JP 2004509446 A JP2004509446 A JP 2004509446A JP 2005528175 A JP2005528175 A JP 2005528175A
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- 230000017531 blood circulation Effects 0.000 title claims abstract description 46
- 230000000747 cardiac effect Effects 0.000 claims abstract description 72
- 238000000034 method Methods 0.000 claims abstract description 18
- 238000005259 measurement Methods 0.000 claims abstract description 11
- 238000013480 data collection Methods 0.000 claims abstract description 8
- 238000003384 imaging method Methods 0.000 claims description 38
- 239000008280 blood Substances 0.000 claims description 19
- 210000004369 blood Anatomy 0.000 claims description 19
- 238000002592 echocardiography Methods 0.000 claims description 7
- 210000004204 blood vessel Anatomy 0.000 claims description 2
- 230000006698 induction Effects 0.000 claims 3
- 230000001133 acceleration Effects 0.000 claims 2
- 238000013213 extrapolation Methods 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 238000004364 calculation method Methods 0.000 claims 1
- 238000001646 magnetic resonance method Methods 0.000 claims 1
- 238000002595 magnetic resonance imaging Methods 0.000 abstract description 6
- 230000005284 excitation Effects 0.000 abstract description 3
- 230000001360 synchronised effect Effects 0.000 abstract description 2
- 238000002583 angiography Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 210000005240 left ventricle Anatomy 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 238000002059 diagnostic imaging Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000005415 magnetization Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 206010002329 Aneurysm Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 230000000454 anti-cipatory effect Effects 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 230000008338 local blood flow Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000001208 nuclear magnetic resonance pulse sequence Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000000264 spin echo pulse sequence Methods 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7285—Specific aspects of physiological measurement analysis for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/567—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution gated by physiological signals, i.e. synchronization of acquired MR data with periodical motion of an object of interest, e.g. monitoring or triggering system for cardiac or respiratory gating
- G01R33/5676—Gating or triggering based on an MR signal, e.g. involving one or more navigator echoes for motion monitoring and correction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0263—Measuring blood flow using NMR
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7253—Details of waveform analysis characterised by using transforms
- A61B5/7257—Details of waveform analysis characterised by using transforms using Fourier transforms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7285—Specific aspects of physiological measurement analysis for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal
- A61B5/7289—Retrospective gating, i.e. associating measured signals or images with a physiological event after the actual measurement or image acquisition, e.g. by simultaneously recording an additional physiological signal during the measurement or image acquisition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7285—Specific aspects of physiological measurement analysis for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal
- A61B5/7292—Prospective gating, i.e. predicting the occurrence of a physiological event for use as a synchronisation signal
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
- G01R33/56308—Characterization of motion or flow; Dynamic imaging
- G01R33/56316—Characterization of motion or flow; Dynamic imaging involving phase contrast techniques
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Description
N=[血流を持つ信号]−[血流の無い基準信号]
N=[血流エンコード勾配を持つ信号]−[血流勾配の無い基準信号]
フーリエ変換は、前記血流の位相エンコードを速度分布に変換する。前記位相コントラスト・ナビゲータに対する選択された領域は、スライスに対して1次元であることができ、選択されたボリュームに対して2次元又は3次元であることができ、好ましくは前記選択された領域は、血流エンコード勾配にそろえられる。位相コントラストRFパルスシーケンスは、印加される場合に、血流を含む領域において共鳴を励起する。もし励起された領域が全体的に、血流内であるならば、前記RF信号の位相は、前記血流の速度に比例する。もし前記励起された領域に他の組織が存在するならば、基準スキャンが行われ、静的な組織背景を減算するために使用される。
Claims (16)
- 関心領域及び血流領域を主磁場内に配置するステップと、
ナビゲータ・エコーを生成するために少なくとも1つの位相コントラスト・ナビゲータ・シーケンスを前記血流領域に印加するステップと、
前記ナビゲータ・エコーから血液移動の測定値を決定するステップと、
前記血液移動の測定値に従って前記関心領域の撮像シーケンスをゲーティングするステップと、
を有する磁気共鳴の方法。 - 前記ナビゲータ・シーケンスが、血流速度を示すナビゲータ・エコーを生成する、請求項1に記載の方法。
- 前記血流領域が、非血液組織をも含み、前記方法が更に、
前記ナビゲータ・エコーに対する非血液組織の寄与を示すナビゲータ・ベースライン測定値を収集するステップ、
を含む、請求項1及び2の一項に記載の方法。 - 少なくとも1心周期にわたり位相コントラスト・ナビゲータを繰り返し印加し、前記心周期にわたり複数の血液移動の測定値を決定するステップと、
前記血液移動の測定値から前記心周期を示す時間対血液移動の心周期プロットを生成するステップと、
を更に含む、請求項1乃至3の何れか一項に記載の方法。 - 撮像されるべき前記心周期の一部を選択するように前記心周期プロットに対して血流測定値の閾値を設定するステップ、
を更に含む、請求項4に記載の方法。 - 前記心周期プロットと心電図信号とを相互に関連付けるステップ、
を更に含む、請求項4及び5の一項に記載の方法。 - 前記心周期プロットの一次導関数を得るステップ、
を更に含む、請求項4乃至6の何れか一項に記載の方法。 - 前記印加されたナビゲータ・シーケンスが、エンコードされた速度及び加速度であるナビゲータ・エコーを生成し、前記方法が更に、
前記心周期における時点を決定するために前記血流の前記速度及び加速度を前記心周期プロットの振幅及び導関数と比較するステップ、
を更に含む、請求項7に記載の方法。 - 前記心周期における前記決定された時点に応答して撮像シーケンス・データ収集を誘発するステップ、
を更に含む、請求項8に記載の方法。 - 誘発時間を決定するために前記心周期プロットの前記一次導関数に基づいて前記心周期プロットに対して少なくとも1つの外挿アルゴリズムを適用するステップと、
前記誘発時間において前記関心領域のデータ収集を誘発するステップと、
を更に含む、請求項7乃至9の何れか一項に記載の方法。 - 前記血流領域の配置を血管と調整するために前記ナビゲータ・シーケンスを調整するステップ、
を更に含む、請求項1乃至10の何れか一項に記載の方法。 - 関心領域及び血流領域が配置された撮像領域内に主磁場を生成する主磁場手段と、
ナビゲータ・エコーを生成するために前記血流領域に対して少なくとも1つの位相コントラスト・ナビゲータ・シーケンスを印加し、前記関心領域に対して撮像シーケンスを印加する手段と、
前記ナビゲータ・エコーから前記血流領域における血液移動を測定する手段と、
前記血液移動の測定値に従って前記撮像シーケンスをゲーティングするゲーティング手段と、
を有する磁気共鳴装置。 - 前記血液移動の測定値から心周期を示す時間対血液移動の心周期プロットを生成する手段、
を更に含む、請求項12に記載の磁気共鳴装置。 - 前記心周期プロットの一次導関数を得る導関数手段、
を更に含む、請求項13に記載の磁気共鳴装置。 - 血流速度を心電図と比較し、これらの間の類似性を見つける比較器手段、
を更に含む、請求項12、13及び14の何れか一項に記載の磁気共鳴装置。 - 外挿アルゴリズムを前記心周期プロットに適用し、
外挿されたデータを一次導関数基準と結合し、
誘発時間を計算し、
前記誘発時間において前記関心領域に対して前記撮像シーケンスを誘発する、
誘発時間計算手段、
を更に含む、請求項12乃至15の何れか一項に記載の磁気共鳴装置。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/162,379 US6922580B2 (en) | 2002-06-04 | 2002-06-04 | Blood flow gated MRI |
PCT/IB2003/002058 WO2003102618A1 (en) | 2002-06-04 | 2003-05-28 | Blood flow gated mri |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2005528175A true JP2005528175A (ja) | 2005-09-22 |
JP4376779B2 JP4376779B2 (ja) | 2009-12-02 |
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Application Number | Title | Priority Date | Filing Date |
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JP2004509446A Expired - Lifetime JP4376779B2 (ja) | 2002-06-04 | 2003-05-28 | 血流同期mri |
Country Status (7)
Country | Link |
---|---|
US (1) | US6922580B2 (ja) |
EP (1) | EP1514129B1 (ja) |
JP (1) | JP4376779B2 (ja) |
AT (1) | ATE382870T1 (ja) |
AU (1) | AU2003232383A1 (ja) |
DE (1) | DE60318438T2 (ja) |
WO (1) | WO2003102618A1 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2011015951A (ja) * | 2009-06-08 | 2011-01-27 | Toshiba Corp | 磁気共鳴イメージング装置 |
JP2011183212A (ja) * | 2011-06-27 | 2011-09-22 | Tokai Univ | 磁気共鳴イメージング装置 |
JP2012254368A (ja) * | 2004-03-26 | 2012-12-27 | Toshiba Corp | 磁気共鳴イメージング装置 |
Families Citing this family (27)
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US7561909B1 (en) * | 2002-09-16 | 2009-07-14 | The United States Of America As Represented By The Department Of Health And Human Services | MRI navigator methods and systems |
DE10256209B4 (de) * | 2002-12-02 | 2007-06-21 | Siemens Ag | Verfahren zur automatischen Bestimmung des tatsächlichen Geschwindigkeitsintervalls eines fließenden Mediums bei Flussmessungen in der Magnetresonanz-Tomographie sowie Kernspintomographiegerät und Computersoftwareprodukt |
US6798199B2 (en) * | 2003-02-06 | 2004-09-28 | Siemens Medical Solutions Usa, Inc. | Method for synchronizing magnetic resonance imaging data to body motion |
JP4820567B2 (ja) * | 2004-03-26 | 2011-11-24 | 株式会社東芝 | 磁気共鳴イメージング装置及び磁気共鳴信号の収集方法 |
US7238027B2 (en) * | 2004-07-20 | 2007-07-03 | Cardiac Pacemakers, Inc. | Device functionality representation tool |
FR2880252A1 (fr) * | 2005-01-06 | 2006-07-07 | Yves Darlas | " nouvelle methode d'analyse et de mesure de la distribution ou de la reserve sanguine coronarienne " |
US8000768B2 (en) * | 2005-01-10 | 2011-08-16 | Vassol Inc. | Method and system for displaying blood flow |
DE102005027438B4 (de) * | 2005-06-14 | 2011-12-22 | Siemens Ag | Verfahren zur EKG-Triggerung einer Messsequenz eines Magnetresonanzgeräts |
US7613496B2 (en) * | 2005-09-22 | 2009-11-03 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging apparatus and magnetic resonance imaging method |
JP4702107B2 (ja) * | 2006-03-03 | 2011-06-15 | 株式会社日立製作所 | 生体光計測装置 |
US7693568B2 (en) * | 2006-03-30 | 2010-04-06 | Medtronic, Inc. | Medical device sensing and detection during MRI |
US8190244B2 (en) * | 2007-01-23 | 2012-05-29 | Case Western Reserve University | Gated optical coherence tomography (OCT) environmental chamber |
US8320647B2 (en) | 2007-11-20 | 2012-11-27 | Olea Medical | Method and system for processing multiple series of biological images obtained from a patient |
BRPI0907547B8 (pt) | 2008-02-28 | 2021-07-27 | Koninklijke Philips Electronics Nv | sistema de ressonância magnética, monitor seguro de pressão sanguínea para a mri, e, método para monitorar um objeto em um campo magnético |
JP2010063871A (ja) * | 2008-08-12 | 2010-03-25 | Toshiba Corp | 磁気共鳴イメージング装置 |
DE102008060049A1 (de) * | 2008-12-02 | 2010-06-17 | Siemens Aktiengesellschaft | Verfahren zur Bestimmung einer Kodierung für eine Flussmessung und Verfahren zur Flussmessung sowie entsprechend ausgestaltete Magnetresonanzanlage |
JP2011156078A (ja) * | 2010-01-29 | 2011-08-18 | Ge Medical Systems Global Technology Co Llc | 磁気共鳴イメージング装置およびプログラム |
US9271658B2 (en) | 2011-01-10 | 2016-03-01 | East Carolina University | Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling |
US9226673B2 (en) * | 2011-01-10 | 2016-01-05 | East Carolina University | Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling |
DE102012216248A1 (de) * | 2012-09-13 | 2014-03-13 | Siemens Aktiengesellschaft | Medizinische Bildgebungsvorrichtung mit einer Sensoreinheit zu einem Erfassen eines physiologischen Signals sowie ein Verfahren zu einem Erfassen eines Herzzyklus eines Patienten |
DE102014206724B4 (de) | 2014-04-08 | 2015-11-12 | Siemens Aktiengesellschaft | Dynamische Bildgebung mit variablem Kontrast |
CA2963866C (en) | 2014-10-14 | 2023-11-07 | East Carolina University | Methods, systems and computer program products for determining hemodynamic status parameters using signals derived from multispectral blood flow and perfusion imaging |
CN107405094A (zh) | 2014-10-14 | 2017-11-28 | 东卡罗莱娜大学 | 用于使用成像技术来可视化解剖结构以及血流和灌注生理机能的方法、系统和计算机程序产品 |
US11553844B2 (en) | 2014-10-14 | 2023-01-17 | East Carolina University | Methods, systems and computer program products for calculating MetaKG signals for regions having multiple sets of optical characteristics |
US10058256B2 (en) | 2015-03-20 | 2018-08-28 | East Carolina University | Multi-spectral laser imaging (MSLI) methods and systems for blood flow and perfusion imaging and quantification |
US10390718B2 (en) | 2015-03-20 | 2019-08-27 | East Carolina University | Multi-spectral physiologic visualization (MSPV) using laser imaging methods and systems for blood flow and perfusion imaging and quantification in an endoscopic design |
JP6996930B2 (ja) * | 2017-10-13 | 2022-01-17 | キヤノンメディカルシステムズ株式会社 | 磁気共鳴イメージング装置 |
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2002
- 2002-06-04 US US10/162,379 patent/US6922580B2/en not_active Expired - Fee Related
-
2003
- 2003-05-28 WO PCT/IB2003/002058 patent/WO2003102618A1/en active IP Right Grant
- 2003-05-28 AT AT03756077T patent/ATE382870T1/de not_active IP Right Cessation
- 2003-05-28 DE DE60318438T patent/DE60318438T2/de not_active Expired - Lifetime
- 2003-05-28 EP EP03756077A patent/EP1514129B1/en not_active Expired - Lifetime
- 2003-05-28 JP JP2004509446A patent/JP4376779B2/ja not_active Expired - Lifetime
- 2003-05-28 AU AU2003232383A patent/AU2003232383A1/en not_active Abandoned
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2012254368A (ja) * | 2004-03-26 | 2012-12-27 | Toshiba Corp | 磁気共鳴イメージング装置 |
JP2013255853A (ja) * | 2004-03-26 | 2013-12-26 | Toshiba Corp | 磁気共鳴イメージング装置 |
US9301704B2 (en) | 2004-03-26 | 2016-04-05 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging system for non-contrast MRA and magnetic resonance signal acquisition method employed by the same |
US9301706B2 (en) | 2004-03-26 | 2016-04-05 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging system for non-contrast MRA and magnetic resonance signal acquisition method employed by the same |
JP2011015951A (ja) * | 2009-06-08 | 2011-01-27 | Toshiba Corp | 磁気共鳴イメージング装置 |
JP2011183212A (ja) * | 2011-06-27 | 2011-09-22 | Tokai Univ | 磁気共鳴イメージング装置 |
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US20030225328A1 (en) | 2003-12-04 |
US6922580B2 (en) | 2005-07-26 |
JP4376779B2 (ja) | 2009-12-02 |
EP1514129A1 (en) | 2005-03-16 |
WO2003102618A1 (en) | 2003-12-11 |
DE60318438D1 (de) | 2008-02-14 |
DE60318438T2 (de) | 2008-12-18 |
EP1514129B1 (en) | 2008-01-02 |
ATE382870T1 (de) | 2008-01-15 |
AU2003232383A1 (en) | 2003-12-19 |
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