JP2005525352A5 - - Google Patents

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Publication number
JP2005525352A5
JP2005525352A5 JP2003570776A JP2003570776A JP2005525352A5 JP 2005525352 A5 JP2005525352 A5 JP 2005525352A5 JP 2003570776 A JP2003570776 A JP 2003570776A JP 2003570776 A JP2003570776 A JP 2003570776A JP 2005525352 A5 JP2005525352 A5 JP 2005525352A5
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JP
Japan
Prior art keywords
pharmaceutical composition
vegfr
composition according
inhibitor
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003570776A
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English (en)
Japanese (ja)
Other versions
JP2005525352A (ja
Filing date
Publication date
Priority claimed from US10/081,126 external-priority patent/US20030180294A1/en
Application filed filed Critical
Publication of JP2005525352A publication Critical patent/JP2005525352A/ja
Publication of JP2005525352A5 publication Critical patent/JP2005525352A5/ja
Pending legal-status Critical Current

Links

JP2003570776A 2002-02-22 2003-02-20 角膜移植片の生存を延長させる方法 Pending JP2005525352A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/081,126 US20030180294A1 (en) 2002-02-22 2002-02-22 Methods of extending corneal graft survival
PCT/US2003/005125 WO2003072029A2 (en) 2002-02-22 2003-02-20 Methods of extending corneal graft survival

Publications (2)

Publication Number Publication Date
JP2005525352A JP2005525352A (ja) 2005-08-25
JP2005525352A5 true JP2005525352A5 (https=) 2006-04-06

Family

ID=27765253

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003570776A Pending JP2005525352A (ja) 2002-02-22 2003-02-20 角膜移植片の生存を延長させる方法

Country Status (6)

Country Link
US (1) US20030180294A1 (https=)
EP (1) EP1476187A4 (https=)
JP (1) JP2005525352A (https=)
AU (1) AU2003215337B2 (https=)
CA (1) CA2476994A1 (https=)
WO (1) WO2003072029A2 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6824777B1 (en) 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
EP1353952B1 (en) 1994-11-14 2007-04-11 Ludwig Institute For Cancer Research Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy
US7125714B2 (en) 1997-02-05 2006-10-24 Licentia Ltd. Progenitor cell materials and methods
KR100402497B1 (ko) * 2000-11-30 2003-10-22 주식회사 엘지이아이 전자레인지의 가열장치
US7611711B2 (en) * 2001-01-17 2009-11-03 Vegenics Limited VEGFR-3 inhibitor materials and methods
US6709655B2 (en) 2001-02-28 2004-03-23 Instituto Bioclon, S.A. De C.V. Pharmaceutical composition of F(ab1)2 antibody fragments and a process for the preparation thereof
WO2003006104A2 (en) * 2001-07-12 2003-01-23 Ludwig Institute For Cancer Research Lymphatic endothelial cells materials and methods
US20040214766A1 (en) * 2001-10-01 2004-10-28 Kari Alitalo VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
US20030113324A1 (en) * 2001-10-01 2003-06-19 Kari Alitalo Neuropilin/VEGF-C/VEGFR-3 materials and methods
US20040248796A1 (en) * 2003-02-04 2004-12-09 Kari Alitalo VEGF-B and PDGF modulation of stem cells
AU2004242586C1 (en) * 2003-05-28 2011-02-24 Regeneron Pharmaceuticals, Inc. Method of treating corneal transplant rejection by using VEGF antagonists
EP1635860A2 (en) * 2003-06-12 2006-03-22 Ludwig Institute For Cancer Research Use of vegf-c or vegf-d in reconstructive surgery
WO2005016963A2 (en) * 2003-06-12 2005-02-24 Ludwig Institute For Cancer Research Heparin binding veger-3 ligands
US20060210563A1 (en) * 2003-07-25 2006-09-21 Juan Lopez De Silanes Administration of anti-cytokine f(ab')2 antibody fragments
US7771742B2 (en) * 2004-04-30 2010-08-10 Allergan, Inc. Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
US7303748B2 (en) 2005-02-02 2007-12-04 Regeneron Pharmaceuticals, Inc. Method of treating eye injury with local administration of a VEGF inhibitor
US20080070855A1 (en) * 2006-09-20 2008-03-20 James Pitzer Gills Treatment with anti-VEGF agents to prevent postoperative inflammation and angiogenesis in normal and diseased eyes
US9073997B2 (en) * 2007-02-02 2015-07-07 Vegenics Pty Limited Growth factor antagonists for organ transplant alloimmunity and arteriosclerosis
CN101815504B (zh) 2007-07-10 2013-11-20 加利福尼亚大学董事会 用于向所选择组织递送组合物的材料和方法
WO2009061830A1 (en) * 2007-11-06 2009-05-14 Massachusetts Eye & Ear Infirmary Methods and compositions for treating conditions associated with angiogenesis using a vascular adhesion protein-1 (vap-1) inhibitor
EP2538965B1 (en) * 2010-02-25 2017-04-12 Schepens Eye Research Institute Therapeutic compositions for the treatment of dry eye disease
JP6105838B2 (ja) * 2010-08-24 2017-03-29 国立大学法人 岡山大学 疼痛の治療剤
US9364535B2 (en) * 2012-08-15 2016-06-14 The Regents Of The University Of California Methods and compositions for modulating lymphangiogenesis, e.g., to treat transplant rejection, in a subject
PT2956476T (pt) 2013-02-18 2020-02-21 Vegenics Pty Ltd Moléculas de ligação e usos destas
JP2020503255A (ja) * 2016-10-27 2020-01-30 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア インテグリンアルファ9の遮断はリンパ弁形成を抑制し、移植片の生存を促進する
CN119055769B (zh) * 2023-08-17 2025-09-05 南方医科大学南方医院 抗血管生成药物在提高软组织移植物保留率中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443505A (en) * 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
US6331313B1 (en) * 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
AU2002236495B2 (en) * 2000-11-29 2006-05-11 Allergan, Inc. Intraocular implants for preventing transplant rejection in the eye
DE10134196B4 (de) * 2001-07-13 2005-08-18 Forschungszentrum Karlsruhe Gmbh Technik Und Umwelt Pharmazeutische Zusammensetzung zur Hemmung der unkontrollierten Vermehrung und/oder Induzierung der Apoptose von Zellen

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